This is a review about PTN, based on 4 published articles (read how Labome selects the articles), using PTN antibody in all methods. It is aimed to help Labome visitors find the most suited PTN antibody.
PTN synonym: HARP; HBGF8; HBNF; NEGF1; HB-GAM; HBBM; HBGF-8; HBNF-1; OSF-1; heparin affin regulatory protein; heparin binding growth factor 8; heparin-binding brain mitogen; heparin-binding growth factor 8; heparin-binding growth-associated molecule; heparin-binding neurite outgrowth-promoting factor 1; neurite growth-promoting factor 1; osteoblast-specific factor 1; pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)

R and D Systems
goat polyclonal
  • WB; rat; 1:400
  • IC; rat; 1:400
R and D Systems PTN antibody (Cell Signaling, AF-252-PB) was used in western blot on rat samples at 1:400 and in immunocytochemistry on rat samples at 1:400. Int J Neuropsychopharmacol (2015) ncbi
not indicated
  • IC; human
R&D Systems anti-PTN antibody was used in immunocytochemistry in order to demonstrate that vasculogenesis in human MM may develop from tumoral production of pleiotrophin, which induces the transdifferentiation of monocytes into VECs.Blood (2009) ncbi
Santa Cruz Biotechnology
not indicated
  • WB; human
  • IP; human
Santa Cruz Biotechnology HARP antibodies (sc-1394 and sc-1395) were used in western blot and immunoprecipitation to characterize heparin affin regulatory peptide signaling in human endothelial cellsJ Biol Chem (2005) ncbi
not indicated
  • IHC; human
Santa Cruz Biotechnology goat anti-human PTN antibody was used in immunohistochemistry (1:400) to study PTN expression in melanocytic lesions and its association with metastatic potential.J Cutan Pathol (2005) ncbi
Articles Reviewed
  1. Daniel García-Pérez et al. (2015). "Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration".PMID 26164717
  2. Haiming Chen et al. (2009). "Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis".PMID 19060246
  3. Apostolos Polykratis et al. (2005). "Characterization of heparin affin regulatory peptide signaling in human endothelial cells".PMID 15797857
  4. H Wu et al. (2005). "Pleiotrophin expression correlates with melanocytic tumor progression and metastatic potential".PMID 15606670