This is a review about PINK1, based on 20 published articles (read how Labome selects the articles), using PINK1 antibody in all methods. It is aimed to help Labome visitors find the most suited PINK1 antibody.
PINK1 synonym: BRPK; PARK6; PTEN-induced putative kinase protein 1; protein kinase BRPK

Novus Biologicals
rabbit polyclonal
  • WB; human
Novus Biologicals PINK1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit polyclonal
  • IHC-P; mouse; 1:50
Novus Biologicals PINK1 antibody (Novus Biologicals, BC100-494) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. PLoS Genet (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1:1,000
In order to examine the involvement of lysine 63-linked polyubiquitin during Parkin-mediated mitophagy, Novus Biologicals PINK1 antibody (Novus Biologicals, BC100-494) was used in western blot on mouse samples at 1:1,000. J Biol Chem (2014) ncbi
rabbit polyclonal
  • WB; human; 1:500
In order to identify E2s that regulate the activation, translocation, and enzymatic functions of Parkin during mitochondrial quality control, Novus Biologicals PINK1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples at 1:500. J Cell Sci (2014) ncbi
rabbit polyclonal
  • WB; human; 1:300
In order to report and characterize the interaction between BECN1 and PARK2, Novus Biologicals PINK1 antibody (Novus, BC100-494) was used in western blot on human samples at 1:300. Autophagy (2014) ncbi
rabbit polyclonal
  • WB; human
  • IC; human
Novus Biologicals PINK1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples and in immunocytochemistry on human samples. Neurobiol Dis (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
Novus Biologicals PINK1 antibody (Novus, BC100-494) was used in western blot on mouse samples at 1:1000. J Biol Chem (2013) ncbi
rabbit polyclonal
  • WB; human
Novus Biologicals polyclonal anti-PINK1 antibody was used to perform immunoblotting in order to study the influence of PINK1, parkin and DJ-1 on alpha-synuclein-mediated inhibition of mitochondrial fusion.EMBO J (2010) ncbi
not indicated
  • WB; human
Novus Biologicals anti-PINK1 antibody was used to carry out western blot analysis in order to investigate the role for CHBP protein from Burkholderia pseudomallei as a potent inhibitor of the eukaryotic ubiquitination pathway.Science (2010) ncbi
not indicated
  • WB; human
Novus Biologicals polyclonal rabbit anti-Pink1 antibody was used for western blot in order to investigate the role of Pink1 in the regulation of mitochondrial trafficking.Biochemistry (2009) ncbi
not indicated
  • WB; human
  • IC; human
Novus anti-PINK1 antibody was used in western blot and immunocytochemistry in order to study the role of PINK1 in Parkinson's diseasePLoS ONE (2008) ncbi
Santa Cruz Biotechnology
rabbit polyclonal (H-300)
  • WB; human
Santa Cruz Biotechnology PINK1 antibody (Santa Cruz, sc-33796) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit polyclonal (H-300)
  • WB; human
Santa Cruz Biotechnology PINK1 antibody (Santa Cruz Biotechnology, sc-33796) was used in western blot on human samples. J Biol Chem (2015) ncbi
rabbit polyclonal (H-300)
  • WB; mouse
  • IP; mouse
Santa Cruz Biotechnology PINK1 antibody (Santa Cruz Biotechnology, sc33796) was used in western blot on mouse samples and in immunoprecipitation on mouse samples. J Cell Mol Med (2015) ncbi
rabbit polyclonal (H-300)
  • WB; mouse
  • WB; rat
In order to study autophagy in the cardiac tissue of mice with a focus on obesity, Santa Cruz Biotechnology PINK1 antibody (Santa Cruz, sc-33796) was used in western blot on mouse samples and on rat samples. J Lipid Res (2015) ncbi
Abcam
rabbit polyclonal
  • IHC; pig
Abcam PINK1 antibody (Abcam, ab23707) was used in immunohistochemistry on pig samples. Cell Mol Life Sci (2015) ncbi
rabbit polyclonal
  • WB; mouse; fig 1
Abcam PINK1 antibody (Abcam, ab23707) was used in western blot on mouse samples (fig 1). Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • WB; human
Abcam PINK1 antibody (abcam, ab23707) was used in western blot on human samples. PLoS ONE (2014) ncbi
Abnova
mouse polyclonal
  • WB; mouse; fig s3
Abnova PINK1 antibody (Abnova, H00065018-A01) was used in western blot on mouse samples (fig s3). Autophagy (2015) ncbi
EMD Millipore
mouse monoclonal (N4/15)
  • IHC-P; mouse; 1:200
  • WB; mouse
EMD Millipore PINK1 antibody (Millipore, N4/15) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 and in western blot on mouse samples. J Immunol (2014) ncbi
LifeSpan Biosciences
mouse monoclonal (38CT20.8.5)
  • WB; mouse
LifeSpan Biosciences PINK1 antibody (LSBio, LS-B3384) was used in western blot on mouse samples. Biochem Biophys Res Commun (2013) ncbi
Everest Biotech
goat polyclonal
  • WB; human; 1:300
In order to report and characterize the interaction between BECN1 and PARK2, Everest Biotech PINK1 antibody (Everest, EB07940) was used in western blot on human samples at 1:300. Autophagy (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • WB; human; 1:300
In order to report and characterize the interaction between BECN1 and PARK2, Sigma-Aldrich PINK1 antibody (Sigma, HPA001931) was used in western blot on human samples at 1:300. Autophagy (2014) ncbi
Articles Reviewed
  1. Sungwoo Park et al. (2015). "Pyruvate stimulates mitophagy via PINK1 stabilization".PMID 26071202
  2. Paul Hsu et al. (2015). "Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy".PMID 25919711
  3. Vasily D Antonenkov et al. (2015). "The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential".PMID 25861990
  4. Nikolai V Gorbunov et al. (2015). "Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis".PMID 25721260
  5. Bharat Jaishy et al. (2015). "Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity".PMID 25529920
  6. Panojot Bifsha et al. (2014). "Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra".PMID 25501001
  7. Kahori Shiba-Fukushima et al. (2014). "Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy".PMID 25336644
  8. Xiaoqing Zhou et al. (2015). "Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer".PMID 25274063
  9. Nathan D Roe et al. (2015). "Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy".PMID 25229693
  10. Fabienne C Fiesel et al. (2014). "A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently".PMID 24928900
  11. Vinay Choubey et al. (2014). "BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria".PMID 24879156
  12. Yi Zhang et al. (2014). "Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury".PMID 24778451
  13. Jing Zou et al. (2014). "Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin".PMID 24722279
  14. Rubén Gómez-Sánchez et al. (2014). "Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression".PMID 24184327
  15. Masahiro Iguchi et al. (2013). "Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation".PMID 23754282
  16. Joungil Choi et al. (2013). "A novel PGC-1α isoform in brain localizes to mitochondria and associates with PINK1 and VDAC".PMID 23688429
  17. Frits Kamp et al. (2010). "Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1".PMID 20842103
  18. Jixin Cui et al. (2010). "Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family".PMID 20688984
  19. Andreas Weihofen et al. (2009). "Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking".PMID 19152501
  20. Alison Wood-Kaczmar et al. (2008). "PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons".PMID 18560593