This is a review about PDPK1, based on 9 published articles (read how Labome selects the articles), using PDPK1 antibody in all methods. It is aimed to help Labome visitors find the most suited PDPK1 antibody.
PDPK1 synonym: PDK1; PDPK2; PDPK2P; PRO0461; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; PkB kinase like gene 1

Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • IP; hamsters
  • WB; hamsters
Santa Cruz Biotechnology PDPK1 antibody (Santa Cruz Biotechnology, sc-17766) was used in immunoprecipitation on hamsters samples and in western blot on hamsters samples. Eur J Pharmacol (2014) ncbi
not indicated
  • IP; human
Santa Cruz Biotechnology anti-PDK1 antibody (E-3) was used in immunoprecipitation to study IKKB phosphorylationJ Biol Chem (2005) ncbi
Abcam
rabbit monoclonal (EPR336(2))
  • IHC-P; human; 1:250
  • WB; human
In order to evaluate the effect of NVP-BEZ235 and MEK inhibitor ADZ4266 on murine mismatch repair deficient tumors, Abcam PDPK1 antibody (Abcam, AB109460) was used in immunohistochemistry - paraffin section on human samples at 1:250 and in western blot on human samples. PLoS ONE (2013) ncbi
Bethyl
rabbit polyclonal
  • IHC-P; human; fig 1
  • IC; human; fig 3d
  • WB; human; fig 2a
Bethyl PDPK1 antibody (Bethyl, A302-130A) was used in immunohistochemistry - paraffin section on human samples (fig 1), in immunocytochemistry on human samples (fig 3d), and in western blot on human samples (fig 2a). Am J Physiol Gastrointest Liver Physiol (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (C49H2)
  • WB; rat
In order to examine the Nrf2-potentiating mechanism of morin and its possible role in intervening PHLPP2-regulated Akt/GSK3beta/Fyn kinase axis, Cell Signaling Technology PDPK1 antibody (Cell Signaling Technology, 3438) was used in western blot on rat samples. Redox Biol (2015) ncbi
rabbit polyclonal
  • WB; human; fig 10
  • WB; mouse; fig 10
Cell Signaling Technology PDPK1 antibody (Cell Signaling, 3061) was used in western blot on human samples (fig 10) and on mouse samples (fig 10). Mol Cell Biol (2015) ncbi
rabbit monoclonal (D37A7)
  • WB; human; fig 10
  • WB; mouse; fig 10
Cell Signaling Technology PDPK1 antibody (Cell Signaling, 5662) was used in western blot on human samples (fig 10) and on mouse samples (fig 10). Mol Cell Biol (2015) ncbi
rabbit polyclonal
  • WB; hamsters
  • IP; hamsters
Cell Signaling Technology PDPK1 antibody (Cell Signaling, 3061) was used in western blot on hamsters samples and in immunoprecipitation on hamsters samples. Eur J Pharmacol (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1:1,000
In order to study the phosphorylation and acetylation of PIMT targets in male and female mice deleted for PIMT, Cell Signaling Technology PDPK1 antibody (Cell Signaling, 3061) was used in western blot on mouse samples at 1:1,000. PLoS ONE (2013) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology PDPK1 antibody (Cell Signaling Technologies, 3061) was used in western blot on human samples. PLoS ONE (2013) ncbi
not indicated
  • IHC; human
Cell Signaling Technology rabbit polyclonal anti-phospho-PDK1 antibody was used in immunohistochemistry to detect phospho-PDK1 in paraffin sections of malignant and benign breast cancers specimens.BMC Cancer (2006) ncbi
BD Biosciences
not indicated
  • WB; human
BD Transduction Laboratories anti-PDK1 antibody was used in western blot to study IKKB phosphorylationJ Biol Chem (2005) ncbi
Articles Reviewed
  1. Fatima Rizvi et al. (2015). "Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes".PMID 26513344
  2. Shan Wang et al. (2015). "Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways".PMID 25582201
  3. Dmitri Kravtsov et al. (2014). "Myosin 5b loss of function leads to defects in polarized signaling: implication for microvillus inclusion disease pathogenesis and treatment".PMID 25258405
  4. Rocío Alcántara-Hernández et al. (2014). "The phosphoinositide-dependent protein kinase 1 inhibitor, UCN-01, induces fragmentation: possible role of metalloproteinases".PMID 25016091
  5. Zhenxia Qin et al. (2013). "Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent".PMID 24224061
  6. Melanie H Kucherlapati et al. (2013). "Genotype directed therapy in murine mismatch repair deficient tumors".PMID 23935891
  7. Simon Hauerslev et al. (2013). "Protein turnover and cellular stress in mildly and severely affected muscles from patients with limb girdle muscular dystrophy type 2I".PMID 23840556
  8. Zhihui Xie et al. (2006). "3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases".PMID 16551362
  9. Hiroshi Tanaka et al. (2005). "3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling".PMID 16207722