This is a review about Notch1, based on 14 published articles (read how Labome selects the articles), using Notch1 antibody in all methods. It is aimed to help Labome visitors find the most suited Notch1 antibody.
Notch1 synonym: TAN1; hN1; Notch homolog 1, translocation-associated; neurogenic locus notch homolog protein 1; translocation-associated notch protein TAN-1

Santa Cruz BiotechnologySanta Cruz Biotechnology Notch1 product
  • immunocytochemistryIn 2004, Salvatore Pece et al. used Santa Cruz Biotechnology Notch1 antibody to study the relevation of human breast carcinogenesis to the loss of negative regulation by numb over notch [ncbi , more ].
  • immunohistochemistryIn 2008, A R Djalilian et al. utilized Santa Cruz Biotechnology Notch1 antibody to study Notch signaling in the corneal epithelium [ncbi , more ]. In 2002, Darren B Taichman et al. applied Santa Cruz Biotechnology Notch1 antibody to study the role of Notch1 and Jagged1 during lung development and vascular morphogenesis [ncbi , more ].
  • western blotIn 2002, Qi Chen et al. applied Santa Cruz Biotechnology Notch1 antibody to study a novel mechanism for the regulation of amyloid precursor protein metabolism (catalog: sc-6014) [ncbi , more ].
Cell Signaling TechnologyCell Signaling Technology Notch1 product
  • immunohistochemistryIn 2008, A R Djalilian et al. utilized Cell Signaling Technology Notch1 antibody to study Notch signaling in the corneal epithelium [ncbi , more ].
  • western blotIn 2010, Julien Moretti et al. utilized Cell Signaling Technology Notch1 antibody to perform western blot in order to study the Notch activation regulated by deubiquitinase activity of eIF3f [ncbi , more ]. Lan Hsin Kuo et al. utilized Cell Signaling Technology Notch1 antibody to perform western blot in order to study the effect of TNF-alpha on gamma-secretase [ncbi , more ] in 2008 and Patricia Chastagner et al. used Cell Signaling Technology Notch1 antibody to perform western blot at 1:2000 dilution in order to show that Notch receptor degradation is regulated by AIP4/Itch in the absence of ligand activation [ncbi , more ]. Yung Feng Liao et al. applied Cell Signaling Technology Notch1 antibody to study amyloid precursor protein cleavage through a JNK-dependent MAPK pathway [ncbi , more ] in 2004 and Neetu Gupta-Rossi et al. used Cell Signaling Technology Notch1 antibody to study the gamma-secretase cleavage of activated Notch receptor directed by monoubiquitination and endocytosis [ncbi , more ].
EMD MilliporeEMD Millipore Notch1 product
  • western blotIn 2003, Matthew J LaVoie et al. utilized EMD Millipore Notch1 antibody to demonstrate that the Notch ligands, Delta and Jagged, undergo ADAM-mediated ectodomain processing followed by PS-mediated intramembrane proteolysis to release signaling fragments [ncbi , more ].
EpitomicsEpitomics Notch1 product
  • western blotIn 2010, Jianhui Ma et al. applied Epitomics Notch1 antibody to carry out western blot analysis in order to investigate the regulation of Notch signaling and cell differentiation by mTOR signaling [ncbi , more ]. In 2009, Helenia Ansuini et al. employed Epitomics Notch1 antibody to generate monoclonal antibodies to evaluate therapeutic potential of targeting EphA2 in pancreatic tumor [ncbi , more ].
AbcamAbcam Notch1 product
  • immunohistochemistryIn 2008, A R Djalilian et al. utilized Abcam Notch1 antibody to study Notch signaling in the corneal epithelium [ncbi , more ].
Developmental Studies Hybridoma BankDevelopmental Studies Hybridoma Bank Notch1 product
  • immunohistochemistryIn 2008, A R Djalilian et al. utilized Developmental Studies Hybridoma Bank Notch1 antibody to study Notch signaling in the corneal epithelium [ncbi , more ].
BD Biosciences
  • flow cytometryIn 2005, Eri Ishiko et al. employed BD Biosciences Notch1 antibody to study that notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1 [ncbi , more ].
S ARTAVANIS-TSAKONAS
  • immunohistochemistryIn 2007, Takeshi Sasamura et al. utilized Notch1 antibody to study the role of O-fut1 in the endocytic transportation of Notch [ncbi , more ].
Articles Reviewed
  1. Julien Moretti et al. (2010). "The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation".PMID 21124883
  2. Helenia Ansuini et al. (2009). "Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer".PMID 20130824
  3. Jianhui Ma et al. (2010). "Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade".PMID 20038814
  4. Lan Hsin Kuo et al. (2008). "Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin".PMID 18667537
  5. Patricia Chastagner et al. (2008). "AIP4/Itch regulates Notch receptor degradation in the absence of ligand".PMID 18628966
  6. A R Djalilian et al. (2008). "Down-regulation of Notch signaling during corneal epithelial proliferation".PMID 18552977
  7. Takeshi Sasamura et al. (2007). "The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila".PMID 17329366
  8. Eri Ishiko et al. (2005). "Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1".PMID 15563463
  9. Salvatore Pece et al. (2004). "Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis".PMID 15492044
  10. Yung Feng Liao et al. (2004). "Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway".PMID 15347683
  11. Neetu Gupta-Rossi et al. (2004). "Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor".PMID 15240571
  12. Matthew J LaVoie et al. (2003). "The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments".PMID 12826675
  13. Darren B Taichman et al. (2002). "Notch1 and Jagged1 expression by the developing pulmonary vasculature".PMID 12242716
  14. Qi Chen et al. (2002). "A novel mechanism for the regulation of amyloid precursor protein metabolism".PMID 12093789