This is a review about NR2B, based on 44 published articles (read how Labome selects the articles), using NR2B antibody in all methods. It is aimed to help Labome visitors find the most suited NR2B antibody.
NR2B synonym: EIEE27; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR3; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B

EMD Millipore
mouse monoclonal
  • WB; mouse; fig 2
EMD Millipore NR2B antibody (Millipore, 05-920) was used in western blot on mouse samples (fig 2). Nature (2016) ncbi
mouse monoclonal
  • WB; rat; 1:2000
In order to study how activation of mGluR2/3 affects NMDAR function, EMD Millipore NR2B antibody (Millipore, 05-920) was used in western blot on rat samples at 1:2000. Exp Neurol (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
In order to study how activation of mGluR2/3 affects NMDAR function, EMD Millipore NR2B antibody (Millipore, 07-398) was used in western blot on rat samples at 1:1000. Exp Neurol (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:500
In order to investigate the regulatory effect of voltage-gated calcium channels on CaMKII in the striatum, EMD Millipore NR2B antibody (Millipore, 07-398) was used in western blot on mouse samples at 1:500. Mol Cell Neurosci (2015) ncbi
mouse monoclonal (1C6.5C4)
  • WB; rat; 1:20
In order to characterize rat cerebellar, hippocampal and cortical postsynaptic densities, EMD Millipore NR2B antibody (EMD Millipore, MAB5778) was used in western blot on rat samples at 1:20. Neuroscience (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:500; fig  5
  • IHC; rat; fig  5
EMD Millipore NR2B antibody (Chemicon, AB1557P) was used in western blot on rat samples at 1:500 (fig  5) and in immunohistochemistry on rat samples (fig  5). Neurobiol Dis (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on rat samples at 1:1000. Mol Psychiatry (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
In order to study the organization of adult hippocampal excitatory and inhibitory circuits and the role played by the N-cadherin/beta-catenin complex, EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on mouse samples at 1:1000. Hippocampus (2014) ncbi
rabbit polyclonal
  • WB; human; 1:500
EMD Millipore NR2B antibody (EMD Millipore, AB1557P) was used in western blot on human samples at 1:500. Thromb Res (2014) ncbi
rabbit polyclonal
  • WB; domestic ferret; 1:500
EMD Millipore NR2B antibody (Millipore, AB1557P) was used in western blot on domestic ferret samples at 1:500. Neural Plast (2013) ncbi
mouse monoclonal
  • WB; rat
In order to study the distinct roles of different calpain isoforms in synaptic neuroprotection and extrasynaptic neurodegeneration mediated by the NMDA receptor, EMD Millipore NR2B antibody (Millipore, 05-920) was used in western blot on rat samples. J Neurosci (2013) ncbi
rabbit polyclonal
  • WB; mouse
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on mouse samples. J Neurosci (2013) ncbi
mouse monoclonal (13A11)
  • WB; mouse; 1:200
  • IP; mouse; 4 ug/time
EMD Millipore NR2B antibody (Chemicon, MAB5220) was used in western blot on mouse samples at 1:200 and in immunoprecipitation on mouse samples at 4 ug/time. Neurobiol Learn Mem (2014) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on rat samples at 1:1000. ASN Neuro (2013) ncbi
rabbit polyclonal
  • WB; rat; 1:500; fig 1
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on rat samples at 1:500 (fig 1). Mol Psychiatry (2014) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on rat samples at 1:1000. Eur J Neurosci (2013) ncbi
mouse monoclonal (1C6.5C4)
  • WB; mouse; 1:5,000
EMD Millipore NR2B antibody (Millipore, MAB5778) was used in western blot on mouse samples at 1:5,000. J Neurosci (2013) ncbi
rabbit polyclonal
  • WB; mouse
EMD Millipore NR2B antibody (Millipore, 06-600) was used in western blot on mouse samples. Eur J Pharmacol (2013) ncbi
rabbit polyclonal
  • WB; mouse; 1:500
EMD Millipore NR2B antibody (Millipore, AB1557P) was used in western blot on mouse samples at 1:500. J Neurochem (2013) ncbi
mouse monoclonal (1C6.5C4)
  • WB; rat; 1:1000
  • IC; rat; 1:20
In order to study the structure and composition of post-synaptic densities during development, EMD Millipore NR2B antibody (Millipore, MAB5778) was used in western blot on rat samples at 1:1000 and in immunocytochemistry on rat samples at 1:20. J Comp Neurol (2010) ncbi
not indicated
  • WB; human
  • IP; human
Chemicon rabbit anti-NR2B antibody was used in western blot and immunoprecipitation to investigate the role of dorsal horn GluR2 internalization in the regulation of NMDA receptor/PKC-dependent nociceptive hypersensitivity.J Neurosci (2009) ncbi
rabbit polyclonal
  • IHC-F; rat; 2 ug/ml
EMD Millipore NR2B antibody (Upstate Biotechnology, 06-600) was used in immunohistochemistry - frozen section on rat samples at 2 ug/ml. J Comp Neurol (2008) ncbi
rabbit polyclonal
  • IHC-F; rat; 1:300
EMD Millipore NR2B antibody (Chemicon, AB1557P) was used in immunohistochemistry - frozen section on rat samples at 1:300. J Comp Neurol (2006) ncbi
rabbit polyclonal
  • IC; rat; 1:200
EMD Millipore NR2B antibody (Chemicon, AB1557P) was used in immunocytochemistry on rat samples at 1:200. J Comp Neurol (2006) ncbi
not indicated
  • WB; human
Upstate Biotechnology NR2B antibody was used in western blot to study cell-autonomous role of TrkB in the establishment of hippocampal Schaffer collateral synapses.J Neurosci (2005) ncbi
Invitrogen
rabbit polyclonal
  • IP; mouse; 1:500
In order to investigate the role of Fbxo2 in regulating NMDAR subunits in the brain, Invitrogen NR2B antibody (Invitrogen, A16629) was used in immunoprecipitation on mouse samples at 1:500. J Neurosci (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:200
In order to study the effect of copper exposure on memory, Invitrogen NR2B antibody (Molecular Probes/Invitrogen, A-6474) was used in western blot on mouse samples at 1:200. J Alzheimers Dis (2015) ncbi
mouse monoclonal (NR2B)
  • WB; rat; 1:1000
In order to study the effect of environment enrichment on maternal immune activation, Invitrogen NR2B antibody (Pierce, MA1-2014) was used in western blot on rat samples at 1:1000. Brain Behav Immun (2014) ncbi
rabbit polyclonal
  • IC; rat; 1:250
  • WB; rat; 1:500
In order to study the roles of the NR2A and NR2B subunits, and of their scaffolding proteins, in remodeling the dendritic architecture of developing hippocampal neurons, Invitrogen NR2B antibody (Life technologies, A-6474) was used in immunocytochemistry on rat samples at 1:250 and in western blot on rat samples at 1:500. PLoS ONE (2014) ncbi
rabbit polyclonal
  • IHC; rat; fig 2
In order to determine the subcellular localization of N-methyl-D-aspartate type of glutamate receptors subunits in the hippocampal mossy fibre-CA3 pyramidal neuron synapses, Invitrogen NR2B antibody (Molecular Probes, A-6474) was used in immunohistochemistry on rat samples (fig 2). Neuroscience (2013) ncbi
mouse monoclonal (B3-13B11)
  • IC; rat
In order to study the LRP1-mediated pathway in retinal ganglion cells, Invitrogen NR2B antibody (Invitrogen, 32-0700) was used in immunocytochemistry on rat samples. J Biol Chem (2012) ncbi
rabbit polyclonal
  • WB; mouse; tbl 1.
In order to identify D1R ligands that directly modulate NMDARs, Invitrogen NR2B antibody (Invitrogen, A-6474) was used in western blot on mouse samples (tbl 1.). Neurochem Int (2012) ncbi
not indicated
  • WB; human
Zymed Laboratories anti-NR2B antibody (1:500) was used for western blot in order to investigate the role of Estradiol in the regulation of nitric oxide formation in primary neuronal cultures.J Neurochem (2009) ncbi
Santa Cruz Biotechnology
goat polyclonal (C-20)
  • WB; human; fig 8
In order to investigate the effect of phosphorylation on the function of phosphodiesterase 10A, Santa Cruz Biotechnology NR2B antibody (Santa Cruz, sc-1469) was used in western blot on human samples (fig 8). J Biol Chem (2015) ncbi
rabbit polyclonal (H-50)
  • WB; rat; 1:200
Santa Cruz Biotechnology NR2B antibody (Santa Cruz, sc-9057) was used in western blot on rat samples at 1:200. Neuroscience (2015) ncbi
goat polyclonal (C-20)
  • WB; rat; 1:500
In order to study the effects of methyl beta-cyclodextrin on GluA1-dependent synaptic potentiation, Santa Cruz Biotechnology NR2B antibody (Santa Cruz Biotechnology, sc-1469) was used in western blot on rat samples at 1:500. J Neurochem (2015) ncbi
rabbit polyclonal (H-50)
  • WB; rat
  • IP; rat
In order to study the relationship between Na/K-ATPase and NMDA receptor in cerebellar neurons, Santa Cruz Biotechnology NR2B antibody (Santa Cruz Biotechnology, sc-9057) was used in western blot on rat samples and in immunoprecipitation on rat samples. Mol Neurobiol (2015) ncbi
goat polyclonal (C-20)
  • WB; mouse; fig 5
In order to delineate the composition of PCDH-gamma complexes and its role in neural development, Santa Cruz Biotechnology NR2B antibody (Santa, sc-1469) was used in western blot on mouse samples (fig 5). Mol Cell Proteomics (2010) ncbi
not indicated
  • IC; human
Santa Cruz Biotechnology anti-NR1 subunit of NMDA receptors antibody was used in immunocytochemistry to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands.Proc Natl Acad Sci U S A (2009) ncbi
BD Biosciences
mouse monoclonal (13/NMDAR2B)
  • WB; human; 1:500
In order to present data from the first donated Lothian Birth Cohort of 1936 and compare it with other aged and diseased samples, BD Biosciences NR2B antibody (BD Biosciences, 610416) was used in western blot on human samples at 1:500. Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (13/NMDAR2B)
  • WB; mouse; 1:1000
In order to investigate the regulatory effect of voltage-gated calcium channels on CaMKII in the striatum, BD Biosciences NR2B antibody (BD Transduction, 610417) was used in western blot on mouse samples at 1:1000. Mol Cell Neurosci (2015) ncbi
mouse monoclonal (13/NMDAR2B)
  • WB; mouse; 1:1000
In order to assess the Src family kinase inhibitor, AZD0530, for treatment of Alzheimer's disease, BD Biosciences NR2B antibody (BD Transduction Laboratories, 610416) was used in western blot on mouse samples at 1:1000. Ann Neurol (2015) ncbi
mouse monoclonal (13/NMDAR2B)
  • WB; rat
BD Biosciences NR2B antibody (BD Biosciences, 610417) was used in western blot on rat samples. PLoS ONE (2014) ncbi
mouse monoclonal (13/NMDAR2B)
  • WB; mouse
BD Biosciences NR2B antibody (BD Transduction Labs, 610417) was used in western blot on mouse samples. J Neuroinflammation (2014) ncbi
not indicated
  • WB; human
BD Transduction Laboratories mouse anti-NR2B antibody was used in western blot to show that CaMKIIalpha is associated with the CaMKII-binding proteins densin-180.J Biol Chem (2005) ncbi
Cell Signaling Technology
rabbit polyclonal
  • WB; rat; 1:200
Cell Signaling Technology NR2B antibody (Cell Signaling, 4208S) was used in western blot on rat samples at 1:200. Neuroscience (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:500
Cell Signaling Technology NR2B antibody (CST, 4208) was used in western blot on rat samples at 1:500. Brain Res Bull (2014) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
Cell Signaling Technology NR2B antibody (CST, 4207) was used in western blot on rat samples at 1:1000. Brain Res Bull (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • WB; mouse; 1:100
In order to assess the Src family kinase inhibitor, AZD0530, for treatment of Alzheimer's disease, Sigma-Aldrich NR2B antibody (Sigma, M2442) was used in western blot on mouse samples at 1:100. Ann Neurol (2015) ncbi
Articles Reviewed
  1. Yuan Mei et al. (2016). "Adult restoration of Shank3 expression rescues selective autistic-like phenotypes".PMID 26886798
  2. Meng Lin Li et al. (2015). "LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment".PMID 26341392
  3. Christopher M Henstridge et al. (2015). "Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse".PMID 26335101
  4. Johanna G Pasek et al. (2015). "Differential CaMKII regulation by voltage-gated calcium channels in the striatum".PMID 26255006
  5. M M Farley et al. (2015). "Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities".PMID 26215919
  6. Graham Atkin et al. (2015). "Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity".PMID 25878288
  7. Corina Russwurm et al. (2015). "Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum".PMID 25762721
  8. Adam C Kaufman et al. (2015). "Fyn inhibition rescues established memory and synapse loss in Alzheimer mice".PMID 25707991
  9. M H Galinato et al. (2015). "Methamphetamine differentially affects BDNF and cell death factors in anatomically defined regions of the hippocampus".PMID 25463524
  10. Roberto Di Maio et al. (2015). "Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats".PMID 25447228
  11. Tae Yong Choi et al. (2015). "Low levels of methyl β-cyclodextrin disrupt GluA1-dependent synaptic potentiation but not synaptic depression".PMID 25418874
  12. Evgeny E Akkuratov et al. (2015). "Functional Interaction Between Na/K-ATPase and NMDA Receptor in Cerebellar Neurons".PMID 25381029
  13. A Ledonne et al. (2015). "Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons".PMID 25266126
  14. Quan Ma et al. (2015). "Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice".PMID 25159668
  15. E J Connors et al. (2014). "Environmental enrichment mitigates the sex-specific effects of gestational inflammation on social engagement and the hypothalamic pituitary adrenal axis-feedback system".PMID 25011058
  16. Joana Fernandes et al. (2014). "In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons".PMID 24960035
  17. Xiaojie Liu et al. (2014). "Intrathecal administration of roscovitine prevents remifentanil-induced postoperative hyperalgesia and decreases the phosphorylation of N-methyl-D-aspartate receptor and metabotropic glutamate receptor 5 in spinal cord".PMID 24769228
  18. Jessica S Nikitczuk et al. (2014). "N-cadherin regulates molecular organization of excitatory and inhibitory synaptic circuits in adult hippocampus in vivo".PMID 24753442
  19. Fernando J Bustos et al. (2014). "PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors".PMID 24705401
  20. Ingrid R Niesman et al. (2014). "Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice".PMID 24593993
  21. Maggie L Kalev-Zylinska et al. (2014). "N-methyl-D-aspartate receptors amplify activation and aggregation of human platelets".PMID 24593912
  22. Yu Ting Mao et al. (2013). "Cross-modal plasticity results in increased inhibition in primary auditory cortical areas".PMID 24288625
  23. Yubin Wang et al. (2013). "Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration".PMID 24285894
  24. Justin Trotter et al. (2013). "Dab1 is required for synaptic plasticity and associative learning".PMID 24068831
  25. Katherine Leaderbrand et al. (2014). "Co-activation of NR2A and NR2B subunits induces resistance to fear extinction".PMID 24055686
  26. Hui Wang et al. (2013). "The GluN3A subunit exerts a neuroprotective effect in brain ischemia and the hypoxia process".PMID 23883441
  27. J Wei et al. (2014). "Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition".PMID 23835908
  28. Subhash C Gupta et al. (2013). "Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat".PMID 23551217
  29. Karina Possa Abrahao et al. (2013). "Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration".PMID 23486954
  30. Akira Nagakura et al. (2013). "Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine".PMID 23276665
  31. L K Berg et al. (2013). "Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses".PMID 23159309
  32. Antoine G Almonte et al. (2013). "Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity".PMID 23113835
  33. Hideki Hayashi et al. (2012). "A potential neuroprotective role of apolipoprotein E-containing lipoproteins through low density lipoprotein receptor-related protein 1 in normal tension glaucoma".PMID 22674573
  34. Mattis B Wigestrand et al. (2012). "Subunit-specific modulation of [(3)H]MK-801 binding to NMDA receptors mediated by dopamine receptor ligands in rodent brain".PMID 22561101
  35. Matthew T Swulius et al. (2010). "Structure and composition of the postsynaptic density during development".PMID 20878786
  36. Meng Hsuan Han et al. (2010). "Proteomics analysis reveals overlapping functions of clustered protocadherins".PMID 19843561
  37. Jang Su Park et al. (2009). "Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons".PMID 19279258
  38. Fernanda G De Felice et al. (2009). "Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers".PMID 19188609
  39. Xavier d'Anglemont de Tassigny et al. (2009). "Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures".PMID 19187438
  40. Yiu Chung Tse et al. (2008). "Developmental expression of NMDA and AMPA receptor subunits in vestibular nuclear neurons that encode gravity-related horizontal orientations".PMID 18335497
  41. Jun Zhang et al. (2006). "Distinct perisynaptic and synaptic localization of NMDA and AMPA receptors on ganglion cells in rat retina".PMID 16927255
  42. A E King et al. (2006). "Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity".PMID 16856139
  43. A J Robison et al. (2005). "Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2".PMID 16120608
  44. Bryan W Luikart et al. (2005). "TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses".PMID 15829629