This is a review about MMP-3, based on 17 published articles (read how Labome selects the articles), using MMP-3 antibody in all methods. It is aimed to help Labome visitors find the most suited MMP-3 antibody.
MMP-3 synonym: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1; matrix metalloproteinase 3 (stromelysin 1, progelatinase); proteoglycanase; transin-1

EMD Millipore
rabbit polyclonal
  • WB; African green monkey
EMD Millipore MMP-3 antibody (Millipore, AB2963) was used in western blot on African green monkey samples. Osteoarthritis Cartilage (2015) ncbi
mouse monoclonal (SL-1 IID4)
  • IHC; human; 1:100
EMD Millipore MMP-3 antibody (Millipore, SL-1 IID4) was used in immunohistochemistry on human samples at 1:100. Acta Derm Venereol (2015) ncbi
mouse monoclonal (SL-1 IID4)
  • WB; human
EMD Millipore MMP-3 antibody (Millipore, MAB3369) was used in western blot on human samples. J Periodontal Res (2015) ncbi
not indicated
  • IHC; human
Calbiochem mouse monoclonal antihuman anti-MMP-3 antibody was used in immunohistochemistry at 1:10 dilution in order to demonstrate that IL-1beta and TNF-alpha induce MMP-1 and MMP-3 activity to promote PTD by degrading decidual and fetal membranesJ Clin Endocrinol Metab (2008) ncbi
not indicated
  • IHC; human
Chemicon mouse monoclonal anti-MMP-3 antibody was used in immunohistochemistry to study the role for activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammation and extracellular matrix degradation in inflammatory acne lesions in vivo in skin cryosections from patients.Am J Pathol (2005) ncbi
Santa Cruz Biotechnology
goat polyclonal (C-19)
  • WB; hamsters
Santa Cruz Biotechnology MMP-3 antibody (Santa Cruz Biotechnology, sc-6839) was used in western blot on hamsters samples. Eur J Pharmacol (2014) ncbi
goat polyclonal (C-19)
  • WB; mouse
Santa Cruz Biotechnology MMP-3 antibody (Santa Cruz, sc-6839) was used in western blot on mouse samples. Exp Cell Res (2014) ncbi
rabbit polyclonal (C-19)
  • ELISA; rat
In order to evaluate the neuroprotective effect of the lipoxin A4 receptor agonist, BML-111, in a rat model of ischemic stroke, Santa Cruz Biotechnology MMP-3 antibody (Santa Cruz, sc-6839-R) was used in ELISA on rat samples. J Neurochem (2014) ncbi
goat polyclonal (C-19)
  • IHC-P; human; 1:100
  • WB; human; 1:1000
Santa Cruz Biotechnology MMP-3 antibody (Santa Cruz Biotechnology, sc-6839) was used in immunohistochemistry - paraffin section on human samples at 1:100 and in western blot on human samples at 1:1000. Arthritis Res Ther (2013) ncbi
not indicated
  • WB; human
Santa Cruze Biotechnology anti-human MMP-3 polyclonal antibody was used for western blot in order to investigate the role of PGE2 on matrix metalloproteinase synthesis in chondrocytes.J Immunol (2010) ncbi
not indicated
  • IHC; human
Santa Cruz goat anti-human MMP-3 IgG was used in immunohistochemistry to measure the TNF-alpha level in monocyte/macrophage cultures cultures in order to study regulation of MMPs, IL-1, and TNF level by IL-17 in periodontitisJ Dent Res (2007) ncbi
R and D Systems
goat polyclonal
  • FC; human
  • IC; human
In order to investigate the effect of TNF and IL-10 on synovial fibroblasts, R and D Systems MMP-3 antibody (R & D Systems, AF513) was used in flow cytometry on human samples and in immunocytochemistry on human samples. Cell Tissue Res (2014) ncbi
mouse monoclonal (10D6)
  • IHC-P; human; 1:50
R and D Systems MMP-3 antibody (R&D Systems, 10D6) was used in immunohistochemistry - paraffin section on human samples at 1:50. Ann Diagn Pathol (2014) ncbi
not indicated
  • WB; human
R/D Systems MMP-3 antibody was used to perform immunoblots in order to study the role of matrix metalloproteinase in pediatric acute lung injury.Int J Med Sci (2009) ncbi
not indicated
  • ELISA; human
R&D Systems MMP-3 elisa kit was used in order to demonstrate that IL-1beta and TNF-alpha induce MMP-1 and MMP-3 activity to promote PTD by degrading decidual and fetal membranesJ Clin Endocrinol Metab (2008) ncbi
not indicated
  • ELISA; human
R&D Systems Quantikine MMP-3 sandwich ELISA kit was used to measure the level of total (pro- and active) MMP-3 in gingival fibroblast cultures in order to study regulation of MMPs, IL-1, and TNF level by IL-17 in periodontitisJ Dent Res (2007) ncbi
Abcam
mouse monoclonal (SPM293)
  • WB; human; 1:1000
Abcam MMP-3 antibody (Abcam, ab17790) was used in western blot on human samples at 1:1000. Mol Cell Biochem (2015) ncbi
BD Biosciences
not indicated
  • WB; human
  • IHC; human
BD Transduction Laboratory anti-MMP-3 antibody was used in western blot and immunohistochemistry to the proteolytic cleavage of extracellularly secreted alpha-synuclein via the activation of MMP-3 in a selective manner.J Biol Chem (2005) ncbi
GE Healthcare Life Biosciences
not indicated
  • ELISA; human
GE Healthcare human biotrak assays were used in ELISA to determin MMP3 level in order to study whether the PTCH1+/- genotype of healthy NBCCS fibroblasts is associated with basal cell carcinoma (BCC).PLoS ONE (2009) ncbi
Articles Reviewed
  1. A V Stone et al. (2015). "Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion".PMID 26033163
  2. Akihiko Uchiyama et al. (2015). "Cutaneous marginal zone B-cell lymphoma evolving into anetoderma: a role of matrix metalloproteinases?".PMID 25350822
  3. Jingjing Zhang et al. (2015). "Effects of p75 neurotrophin receptor on regulating hypoxia-induced angiogenic factors in retinal pigment epithelial cells".PMID 25200140
  4. A Romero et al. (2015). "Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts".PMID 25073540
  5. Rocío Alcántara-Hernández et al. (2014). "The phosphoinositide-dependent protein kinase 1 inhibitor, UCN-01, induces fragmentation: possible role of metalloproteinases".PMID 25016091
  6. Nobuaki Ozeki et al. (2014). "IL-1β-induced, matrix metalloproteinase-3-regulated proliferation of embryonic stem cell-derived odontoblastic cells is mediated by the Wnt5 signaling pathway".PMID 24851717
  7. I Mrosewski et al. (2014). "Regulation of osteoarthritis-associated key mediators by TNFα and IL-10: effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line".PMID 24816983
  8. Rodolfo Villarreal-Calderon et al. (2014). "Antral atrophy, intestinal metaplasia, and preneoplastic markers in Mexican children with Helicobacter pylori-positive and Helicobacter pylori-negative gastritis".PMID 24656654
  9. Kimberly E Hawkins et al. (2014). "Neurovascular protection by post-ischemic intravenous injections of the lipoxin A4 receptor agonist, BML-111, in a rat model of ischemic stroke".PMID 24225006
  10. Akihiko Hasegawa et al. (2013). "Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis".PMID 23406989
  11. Marjolaine Gosset et al. (2010). "Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1".PMID 20943996
  12. Alexandre Valin et al. (2009). "PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts".PMID 19287498
  13. Michele Y F Kong et al. (2009). "Matrix metalloproteinase activity in pediatric acute lung injury".PMID 19159011
  14. Ceyda Oner et al. (2008). "Progestin-inflammatory cytokine interactions affect matrix metalloproteinase-1 and -3 expression in term decidual cells: implications for treatment of chorioamnionitis-induced preterm delivery".PMID 17940116
  15. A Beklen et al. (2007). "MMPs, IL-1, and TNF are regulated by IL-17 in periodontitis".PMID 17384030
  16. Sewon Kang et al. (2005). "Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo".PMID 15920154
  17. Jee Young Sung et al. (2005). "Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases".PMID 15863497