This is a review about MLH1, based on 23 published articles (read how Labome selects the articles), using MLH1 antibody in experiments. It is aimed to help Labome visitors find the most suited MLH1 antibody.
MLH1 synonym: COCA2; FCC2; HNPCC; HNPCC2; hMLH1; DNA mismatch repair protein Mlh1; mutL homolog 1, colon cancer, nonpolyposis type 2

  • Santa Cruz Biotechnology anti-MLH1 antibody (sc-582) was used in western blot to study rapid alkylation-induced recruitment of DNA repair proteins to chromosomal DNA within synchronized populations of MMR proficient cells (HeLa MR) after MNNG treatment. (catalog: sc-582) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology4MLH1 antibodysc-582
    EMD Millipore2MLH1 antibody
    Novus Biologicals1MLH1 antibody
    BD Biosciences8MLH1 antibody
    Table 1. MLH1 antibody western blot.
  • Santa Cruz Biotechnology anti-MLH1 antibody was used for western blot in order to investigate the roles of MutSalpha and MutLalpha in the regulation of ATR-Chk1 pathway.ncbi, more
  • Santa Cruz Biotechnology anti-hMLH1 antibody was used in immunocytochemistry (1:25) to demonstrate that heparanase was expressed in lymphocytes of breast cancer PBMC.ncbi, more
  • Santa Cruz Biotechnology anti-Mlh1 antibody was used in western blot to study the role of MED1 in DNA damage response.ncbi, more
  • Santa Cruz Biotechnology anti-hMlh1 antibody was used in western blot to study the functional alterations of human exonuclease 1 mutants in atypical hereditary nonpolyposis colorectal cancer syndrome.ncbi, more
  • Calbiochem anti-MLH1 antibody (1:75) was used to perform western blot and immunoprecipitation in order to study the function of small ubiquitin-related modifier (SUMO) 1, SUMO-2/3 and SUMOylation.ncbi, more
  • suppliernumreagent link
    BD Biosciences7MLH1 antibody
    Table 2. MLH1 antibody immunohistochemistry.
  • Calbiochem anti-MLH1 (Ab-1) was used in western blot to study the role for the mismatch repair protein PMS2 in the regulation of apoptosis by interacting with the p53-related transcription factor p73.ncbi, more
  • Novus Biologicals hMTH antibody (1:1000) was used in western blot in order to compare the protective effects of the four main lesion-specific DNA glycosylase repair genes.ncbi, more
  • BD Biosciences anti-MLH1 antibody (554073) was used in immunocytochemistry to study rapid alkylation-induced recruitment of DNA repair proteins to chromosomal DNA within synchronized populations of MMR proficient cells (HeLa MR) after MNNG treatment.ncbi, more
  • BD Biosciences mouse anti-MLH1 antibody was used for western blot in order to investigate the role of Syce1 in the regulation of Synapsis and DNA Repair.ncbi, more
  • BD PharMingen monoclonal anti-hMLH1 antibody (clone G168-15) was used in immunohistochemistry to evaluate the association of MSI and MMR status with outcome and with thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) expression in colorectal cancerncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1MLH1 antibody
    BD Biosciences4MLH1 antibody
    Table 3. MLH1 antibody immunocytochemistry.
  • BD Pharmingen anti-human mouse MLH1 (clone G168-728) antibody was used to perform immunohistochemistry in order to show that women diagnosed with endometrial cancer before age 50 will have a mismatch repair deficiency.ncbi, more
  • PharMingen anti-hMLH1 antibody was used in immunocytochemistry to show the synergistic cytotoxicity of VPA and cisplatin in ovarian cancer cells.ncbi, more
  • Pharmingen mouse monoclonal anti-human MLH-1 (clone G168-15, 1:50) antibody was used to perform immunohistochemistry in order to study the frequency of additional mismatch repair protein MSH-6 mutation in sebaceous gland neoplasms.ncbi, more
  • Pharmingen monoclonal MLH1 antibody (SWE38) was used in immunocytochemistry to study the role of RAD51C and XRCC3 in genetic recombination and DNA repairncbi, more
  • BD Biosciences mouse anti-MLH1 monoclonal antibody was used in western blot and ELISA to study the interaction between RECQ1 helicase and human mismatch repair factorsncbi, more
  • suppliernumreagent link
    EMD Millipore1MLH1 antibody
    BD Biosciences1MLH1 antibody
    Table 4. MLH1 antibody immunoprecipitation.
  • Pharmingen monoclonal hMLH1 antibody was used in immunohistochemistry to study the biological features of hereditary nonpolyposis colorectal cancer (HNPCC) in Chinese population.ncbi, more
  • Becton-Dickinson mouse monoclonal anti-MLH-1 antibody was used in immunohistochemistry to study expression of secreted frizzled receptor protein 1 in patients with hyperplastic polyposis coli syndrome..ncbi, more
  • PharMingen anti-MLH1 antibodies were used in western blot to study the association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2ncbi, more
  • Pharmingen mouse monoclonal MLH1 antibody (G168-15) was used in immunohistochemistry and Western blot to study the biological features of MLH1 mutation originating from northern Italy.ncbi, more
  • Pharmingen MLH1 antibody (G168-15) was used in immunohistochemistry and Western blot to study the biological features of MLH1 expression during CDDP-based chemotherapy.ncbi, more
  • suppliernumreagent link
    BD Biosciences1MLH1 antibody
    Table 5. MLH1 antibody ELISA.
  • Pharmingen hMLH1 antibody (G168-15) was used in Western blot to study the biological function of hMutS alpha on DNA binding.ncbi, more
  • Pharmingen monoclonal anti-hMLH1 antibodies G168-15 and G168-728 were used in Western blot, immunoprecipitation, and immunocytochemistry to study the biological function of hMLH1 BLM interaction.ncbi, more
  • PharMingen anti-MLH1 antibody was used in western blot to study the role of PCNA in mismatch repair by interaction with hMSH3 and hMSH6.ncbi, more
Articles Reviewed
  1. Yiyong Liu et al. (2010). "Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway".PMID 20029092
  2. Ewelina Bolcun-Filas et al. (2009). "Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair".PMID 19247432
  3. Søren A Jensen et al. (2009). "Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression".PMID 19154585
  4. Petrice W Brown et al. (2008). "Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men".PMID 18694876
  5. Allen G Schroering et al. (2008). "Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment".PMID 18468964
  6. Kellie S Matthews et al. (2008). "Lynch syndrome in women less than 50 years of age with endometrial cancer".PMID 18448750
  7. Ching Tai Lin et al. (2008). "Valproic acid resensitizes cisplatin-resistant ovarian cancer cells".PMID 18429963
  8. Vishes Chhibber et al. (2008). "MSH-6: extending the reliability of immunohistochemistry as a screening tool in Muir-Torre syndrome".PMID 18065960
  9. Thérèse Rachell Theodoro et al. (2007). "Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis".PMID 17603633
  10. Yilun Liu et al. (2007). "Role of RAD51C and XRCC3 in genetic recombination and DNA repair".PMID 17114795
  11. Kevin M Doherty et al. (2005). "RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination".PMID 15886194
  12. Ding Cun Luo et al. (2005). "Clinicopathological and molecular genetic analysis of HNPCC in China".PMID 15786548
  13. Ted M Kremer et al. (2004). "Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase".PMID 15450125
  14. Barbara I Oberschmid et al. (2004). "Distinct secreted Frizzled receptor protein 1 staining pattern in patients with hyperplastic polyposis coli syndrome".PMID 15335268
  15. Kate Lillard-Wetherell et al. (2004). "Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2".PMID 15229185
  16. O Caluseriu et al. (2004). "A founder MLH1 mutation in families from the districts of Modena and Reggio-Emilia in northern Italy with hereditary non-polyposis colorectal cancer associated with protein elongation and instability".PMID 14985405
  17. Salvatore Cortellino et al. (2003). "The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity".PMID 14614141
  18. Kentaro Kishi et al. (2003). "Reduced MLH1 expression after chemotherapy is an indicator for poor prognosis in esophageal cancers".PMID 14555508
  19. Hideki Shimodaira et al. (2003). "Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin".PMID 12601175
  20. Xuemin Sun et al. (2002). "Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome".PMID 12414623
  21. Guido Plotz et al. (2002). "hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA".PMID 11809883
  22. G Pedrazzi et al. (2001). "Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1".PMID 11691925
  23. H E Kleczkowska et al. (2001). "hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci".PMID 11274057