This is a review about MK2, based on 15 published articles (read how Labome selects the articles), using MK2 antibody in experiments. It is aimed to help Labome visitors find the most suited MK2 antibody.
MK2 synonym: MAPKAP-K2; MK-2; MK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2

  • Assay Designs anti-MK2 antibody was used to carry out western blot analysis in order to investigate the role for p38 MAPKAPK2 kinase cascade in yolk cell movement process by regulating the activity of F-actin.ncbi, more
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    Enzo Life Sciences1MK2 antibody
    EMD Millipore1MK2 antibody
    Cell Signaling Technology11MK2 antibody
    Table 1. MK2 antibody western blot.
  • Upstate polyclonal anti-MAPKAP kinase 2 (MK2) antibody was used in human HeLa cells and in western blot to study the role for the effects of MK2 on the regulation of HSF1 in inhibiting transcriptional activity and promotes HSP90 binding.ncbi, more
  • Upstate Biotechnology polyclonal anti-MAPKAP-2-kinase antibody was used in immunoprecipitation to study activation of the Rac1/p38 MAP kinase pathway in response to all-trans-retinoic acid.ncbi, more
Cell Signaling TechnologyCell Signaling Technology MK2 product
  • Cell Signaling Technology anti-MAPKAPK 2 (pT334) was used in 1ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry.ncbi, more
  • Cell Signaling Technology anti-phospho-MK2 (Thr334) and anti-MK2 antibodies were used to carry out western blot analysis in order to investigate the mechanism for vaccinia virus double-stranded RNA binding protein E3 inhibiting the expression of cytokines.ncbi, more
  • Cell Signaling Technology antibodies against MK2 were used to investigate the role of p38alpha MAPK in the regulation of macrophage apoptosis.ncbi, more
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    Cell Signaling Technology2MK2 antibody
    Table 2. MK2 antibody immunocytochemistry.
  • Cell Signaling anti-phospho-MK2 antibody was used to carry out western blot analysis in order to investigate the role for p38 MAPKAPK2 kinase cascade in yolk cell movement process by regulating the activity of F-actin.ncbi, more
  • Cell Signaling anti-phospho-MK2 antibody was used for western blot in order to investigate the role of MK2 in the regulation of actin polymerization and vascular leakncbi, more
  • Cell Signaling Technology anti-MK2 and anti-phospho-MK2 antibodies were used in western blot to demonstrate the critical role of hypoxia in activating p38 MAPK and androgen independent androgen receptor stabilization and activity, causing increased aggressiveness of LNCaP cells.ncbi, more
  • Cell Signaling Technology anti-phospho-MK2 antibody was used for western blot in order to investigate the role of Ser326 phosphorylation of Plk1 in the regulation of its functions during mitotic progression.ncbi, more
  • Cell Signaling rabbit polyclonal anti-MAPKAPK-2 antibody (1:1000) was used in western blot in order to demonstrate that human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) induces cell cycle G2 arrest through a Srk1/MK2-mediated mechanism.ncbi, more
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    Cell Signaling Technology1MK2 antibody
    Table 3. MK2 antibody ELISA.
  • Cell Signaling Technologies rabbit phospho-MAPKAPK2 (Thr334) antibody was used in immunocytochemistry at a dilution of 1:100 to investigate whether CCM2 is expressed during mouse preimplantation development and to determine whether this scaffolding protein is associated with p38 MAPK activation following exposure of preimplantation embryos to hyperosmotic environments.ncbi, more
  • Cell Signaling polyclonal anti-phospho-MK2 (Thr-334) antibody was used in human HeLa cells and in western blot to study the role for the effects of MK2 on the regulation of HSF1 in inhibiting transcriptional activity and promotes HSP90 binding.ncbi, more
  • Cell Signaling phospho-MAPKAPK2 antibody was used in western blot to investigate regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation.ncbi, more
  • Cell Signaling Technology phospho-MAPKAPK-2 antibody was used in western blot to study IL-1 beta-inducd MAPKAPK-2 phosphorylation in rat ATII cells.ncbi, more
  • Cell Signaling phosphospecific MK2 antibody (Thr 334) was used in western blot to demonstrate a role for HuR and MK2 in regulating the expression of uPA and uPAR genes at the posttranscriptional level.ncbi, more
  • suppliernumreagent link
    EMD Millipore1MK2 antibody
    Table 4. MK2 antibody immunoprecipitation.
RESEARCH BIOCHEMICALS INTERNATIONAL
  • Research Biochemicals International anti-MK2 antibody was used in immunoprecipitation to study activation of p38-dependent MK2 in human neutrophils.ncbi, more
GENEX BIOSCIENCE
  • Genex Bioscience rabbit polyclonal anti-MK2 antibody was used in immunoprecipitation and western blot to demonstrate a role for HuR and MK2 in regulating the expression of uPA and uPAR genes at the posttranscriptional level.ncbi, more
Articles Reviewed
  1. Sean C Bendall et al. (2011). "Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum".PMID 21551058
  2. Chad Myskiw et al. (2009). "Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways".PMID 19369349
  3. Tracie A Seimon et al. (2009). "Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice".PMID 19287091
  4. Beth A Holloway et al. (2009). "A novel role for MAPKAPK2 in morphogenesis during zebrafish development".PMID 19282986
  5. Mahendra Damarla et al. (2009). "Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury".PMID 19240800
  6. L Khandrika et al. (2009). "Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer".PMID 19151763
  7. J Tang et al. (2008). "Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression".PMID 18695677
  8. Sylvain Huard et al. (2008). "Human immunodeficiency virus type 1 Vpr induces cell cycle G2 arrest through Srk1/MK2-mediated phosphorylation of Cdc25".PMID 18160429
  9. Barry Fong et al. (2007). "Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation".PMID 17214902
  10. XiaoZhe Wang et al. (2006). "Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding".PMID 16278218
  11. Guillaume Bossis et al. (2005). "Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation".PMID 16055710
  12. Jeremie Roux et al. (2005). "Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway".PMID 15755725
  13. Hoanh Tran et al. (2003). "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2".PMID 14517288
  14. Y Alsayed et al. (2001). "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid".PMID 11060298
  15. M J Rane et al. (2001). "p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils".PMID 11042204