This is a review about MK2, based on 14 published articles (read how Labome selects the articles), using MK2 antibody in all methods. It is aimed to help Labome visitors find the most suited MK2 antibody.
MK2 synonym: MAPKAP-K2; MK-2; MK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2

Cell Signaling TechnologyCell Signaling Technology MK2 product
  • ELISAIn 2005, Jeremie Roux et al. utilized Cell Signaling Technology MK2 antibody to study IL-1 beta-inducd MAPKAPK-2 phosphorylation in rat ATII cells [ncbi , more ].
  • immunocytochemistryIn 2009, Tracie A Seimon et al. employed Cell Signaling Technology MK2 antibody to investigate the role of p38alpha MAPK in the regulation of macrophage apoptosis [ncbi , more ]. In 2007, Barry Fong et al. used Cell Signaling Technology MK2 antibody to investigate whether CCM2 is expressed during mouse preimplantation development and to determine whether this scaffolding protein is associated with p38 MAPK activation following exposure of preimplantation embryos to hyperosmotic environments [ncbi , more ].
  • western blotCell Signaling Technology MK2 antibody was employed in 2009 to investigate the role of p38alpha MAPK in the regulation of macrophage apoptosis [ncbi , more ], to carry out western blot analysis in order to investigate the role for p38 MAPKAPK2 kinase cascade in yolk cell movement process by regulating the activity of F-actin [ncbi , more ], to investigate the role of MK2 in the regulation of actin polymerization and vascular leak [ncbi , more ], to demonstrate the critical role of hypoxia in activating p38 MAPK and androgen independent androgen receptor stabilization and activity, causing increased aggressiveness of LNCaP cells [ncbi , more ]and to carry out western blot analysis in order to investigate the mechanism for vaccinia virus double-stranded RNA binding protein E3 inhibiting the expression of cytokines [ncbi , more ]. J Tang et al. applied Cell Signaling Technology MK2 antibody to investigate the role of Ser326 phosphorylation of Plk1 in the regulation of its functions during mitotic progression [ncbi , more ] in 2008 and Sylvain Huard et al. used Cell Signaling Technology MK2 antibody to demonstrate that human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) induces cell cycle G2 arrest through a Srk1/MK2-mediated mechanism [ncbi , more ]. In 2006, XiaoZhe Wang et al. utilized Cell Signaling Technology MK2 antibody to study the role for the effects of MK2 on the regulation of HSF1 in inhibiting transcriptional activity and promotes HSP90 binding [ncbi , more ]. Guillaume Bossis et al. employed Cell Signaling Technology MK2 antibody to investigate regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation [ncbi , more ] in 2005 and Jeremie Roux et al. used Cell Signaling Technology MK2 antibody to study IL-1 beta-inducd MAPKAPK-2 phosphorylation in rat ATII cells [ncbi , more ]. In 2003, Hoanh Tran et al. utilized Cell Signaling Technology MK2 antibody to demonstrate a role for HuR and MK2 in regulating the expression of uPA and uPAR genes at the posttranscriptional level [ncbi , more ].
Enzo Life SciencesEnzo Life Sciences MK2 product
  • western blotIn 2009, Beth A Holloway et al. employed Enzo Life Sciences MK2 antibody to carry out western blot analysis in order to investigate the role for p38 MAPKAPK2 kinase cascade in yolk cell movement process by regulating the activity of F-actin [ncbi , more ].
EMD MilliporeEMD Millipore MK2 product
  • immunoprecipitationIn 2001, Y Alsayed et al. utilized EMD Millipore MK2 antibody to study activation of the Rac1/p38 MAP kinase pathway in response to all-trans-retinoic acid [ncbi , more ].
  • western blotIn 2006, XiaoZhe Wang et al. utilized EMD Millipore MK2 antibody to study the role for the effects of MK2 on the regulation of HSF1 in inhibiting transcriptional activity and promotes HSP90 binding [ncbi , more ].
RESEARCH BIOCHEMICALS INTERNATIONAL
  • immunoprecipitationIn 2001, M J Rane et al. utilized MK2 antibody to study activation of p38-dependent MK2 in human neutrophils [ncbi , more ].
GENEX BIOSCIENCE
  • immunoprecipitationIn 2003, Hoanh Tran et al. utilized MK2 antibody to demonstrate a role for HuR and MK2 in regulating the expression of uPA and uPAR genes at the posttranscriptional level [ncbi , more ].
  • western blotIn 2003, Hoanh Tran et al. utilized MK2 antibody to demonstrate a role for HuR and MK2 in regulating the expression of uPA and uPAR genes at the posttranscriptional level [ncbi , more ].
Articles Reviewed
  1. Chad Myskiw et al. (2009). "Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways".PMID 19369349
  2. Tracie A Seimon et al. (2009). "Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice".PMID 19287091
  3. Beth A Holloway et al. (2009). "A novel role for MAPKAPK2 in morphogenesis during zebrafish development".PMID 19282986
  4. Mahendra Damarla et al. (2009). "Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury".PMID 19240800
  5. L Khandrika et al. (2009). "Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer".PMID 19151763
  6. J Tang et al. (2008). "Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression".PMID 18695677
  7. Sylvain Huard et al. (2008). "Human immunodeficiency virus type 1 Vpr induces cell cycle G2 arrest through Srk1/MK2-mediated phosphorylation of Cdc25".PMID 18160429
  8. Barry Fong et al. (2007). "Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation".PMID 17214902
  9. XiaoZhe Wang et al. (2006). "Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding".PMID 16278218
  10. Guillaume Bossis et al. (2005). "Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation".PMID 16055710
  11. Jeremie Roux et al. (2005). "Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway".PMID 15755725
  12. Hoanh Tran et al. (2003). "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2".PMID 14517288
  13. Y Alsayed et al. (2001). "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid".PMID 11060298
  14. M J Rane et al. (2001). "p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils".PMID 11042204