This is a review about MEK1, based on 63 published articles (read how Labome selects the articles), using MEK1 antibody in all methods. It is aimed to help Labome visitors find the most suited MEK1 antibody.
MEK1 synonym: CFC3; MAPKK1; MEK1; MKK1; PRKMK1; ERK activator kinase 1; MAPK/ERK kinase 1; MAPKK 1; MEK 1; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)

Santa Cruz Biotechnology
rabbit polyclonal (Ser 218/Ser 222)
  • WB; rat; 1:1000
In order to investigate the role of p18, Rab4, Rab7, and Rab9 in vessel formation within the pulmonary vasculature, Santa Cruz Biotechnology MEK1 antibody (Santa Cruz Biotechnology, sc-7995-R) was used in western blot on rat samples at 1:1000. Am J Physiol Lung Cell Mol Physiol (2015) ncbi
rabbit polyclonal (12-B)
  • WB; rat; 1:1000
In order to investigate the role of p18, Rab4, Rab7, and Rab9 in vessel formation within the pulmonary vasculature, Santa Cruz Biotechnology MEK1 antibody (Santa Cruz Biotechnology, sc-436) was used in western blot on rat samples at 1:1000. Am J Physiol Lung Cell Mol Physiol (2015) ncbi
mouse monoclonal (B-4)
  • WB; human; fig 6
In order to test if celastrol inhibits formation of neutrophil extracellular traps induced by inflammatory stimuli associated with rheumatoid arthritis and systemic lupus erythematosus, Santa Cruz Biotechnology MEK1 antibody (Santa Cruz Biotechnology, sc-271914) was used in western blot on human samples (fig 6). Curr Mol Med (2015) ncbi
rabbit polyclonal (C-18)
  • WB; human
Santa Cruz Biotechnology MEK1 antibody (Santa Cruz Biotechnology, sc-219) was used in western blot on human samples. J Cell Physiol (2014) ncbi
not indicated
  • WB; human
  • FC; human
Santa Cruz Biotechnology anti-MEK1 antibody was used to perform western blot and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10.J Immunol (2010) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-human MEK-1 (H-8) monoclonal antibody was used to perform western blot in order to study the role of calmodulin kinase in ligand-independent EGFR degradation in pregnancy.Am J Physiol Cell Physiol (2008) ncbi
not indicated
  • WB; human
  • ELISA; human
Santa Cruz anti-phospho-MEK1/2 antibody (S217/221) and anti-MEK1/2 antibody (H8) were used in western blot and ELISA to study the potential binding partners to Cot and their region of association by separating proteins that were pulled-down with various Cot constructs following immunoprecipiation in human HEK293 cells and Hela cells.Mol Cells (2008) ncbi
not indicated
  • WB; human
  • IC; human
SCBT MEK1 polyclonal antibody was used to investigate the role of GIT1 in ERK1/2 activation during focal adhesionsJ Biol Chem (2005) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-MEK antibody was used in western blot to study the immortalization of bovine lens epithelial cells by human telomerase reverse transcriptaseJ Biol Chem (2005) ncbi
Invitrogen
rabbit monoclonal (22HCLC)
  • WB; human
In order to identify proviral and antiviral host factors in SARS viral replication, Invitrogen MEK1 antibody (Life Technlogies, 710446) was used in western blot on human samples. J Virol (2015) ncbi
mouse monoclonal (3D9)
  • PLA; human; 1:100; fig 8
In order to elucidate how protein tyrosine phosphatase interacting protein 51 modulates the NF-kappaB signaling pathway, Invitrogen MEK1 antibody (Life Technologies, 13-3500) was used in proximity ligation assay on human samples at 1:100 (fig 8). Biomolecules (2015) ncbi
rabbit polyclonal
  • WB; human; fig 4
In order to study the molecular mechanisms underlying malignant changes of meningioma cells, Invitrogen MEK1 antibody (Invitrogen, 44460G) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
R and D Systems
mouse monoclonal (239416)
  • IC; human; 1:50; fig 4
In order to describe the proxHCR method for the detection of protein interactions and posttranslational modifications in microscopy and flow cytometry, R and D Systems MEK1 antibody (RnD, mab2678) was used in immunocytochemistry on human samples at 1:50 (fig 4). Nat Commun (2015) ncbi
rabbit polyclonal
  • IHC; human; 1:100; fig 6
  • WB; human; 1:1000; fig 4
In order to assess the role of the MEK1/2-ERK1/2 signaling pathway in the pathogenesis of chronic rhinosinusitis with nasal polyps, R and D Systems MEK1 antibody (R&D Systems Inc., AF2506) was used in immunohistochemistry on human samples at 1:100 (fig 6) and in western blot on human samples at 1:1000 (fig 4). Arch Immunol Ther Exp (Warsz) (2014) ncbi
mouse monoclonal (239416)
  • IHC; human; 1:50; fig 6
  • WB; human; 1:2000; fig 4
In order to assess the role of the MEK1/2-ERK1/2 signaling pathway in the pathogenesis of chronic rhinosinusitis with nasal polyps, R and D Systems MEK1 antibody (R&D Systems Inc., MAB2678) was used in immunohistochemistry on human samples at 1:50 (fig 6) and in western blot on human samples at 1:2000 (fig 4). Arch Immunol Ther Exp (Warsz) (2014) ncbi
Epitomics
rabbit monoclonal
  • WB; human
Epitomics MEK1 antibody (Epitomics, 1470-1) was used in western blot on human samples. Oncogene (2015) ncbi
EMD Millipore
rabbit polyclonal
  • WB; human
Millipore polyclonal anti-MEK1 antibody was used to carry out western blot assays in order to investigate the molecular mechanisms of GRASP55 and GRASP65 in Golgi cisternal stacking.J Cell Biol (2010) ncbi
not indicated
  • WB; human
Upstate Technologies MAPKK1 antibody was used in western blot in order to demonstrate that celastrol inhibits lethal toxin-induced death of RAW264.7 murine macrophagesPLoS ONE (2008) ncbi
Cell Signaling Technology
rabbit monoclonal (41G9)
  • WB; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology MEK1 antibody (Cell Signaling, 9154) was used in western blot on human samples. PLoS ONE (2015) ncbi
mouse monoclonal (61B12)
  • WB; human
Cell Signaling Technology MEK1 antibody (CST, 2352) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (CST, 9154) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit polyclonal
  • WB; human
In order to study the effect of using an ADAM17 inhibitory antibody, MEDI3622, in several EGFR-dependent tumor models, Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9121) was used in western blot on human samples. Mol Cancer Ther (2015) ncbi
rabbit monoclonal (41G9)
  • WB; mouse
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9154) was used in western blot on mouse samples. Basic Res Cardiol (2015) ncbi
rabbit monoclonal (30C8)
  • WB; human; 1:1000; fig  6
Cell Signaling Technology MEK1 antibody (Cell Signalling Technology, 9146) was used in western blot on human samples at 1:1000 (fig  6). Cell Signal (2015) ncbi
rabbit monoclonal (41G9)
  • WB; human; 1:1000; fig  6
Cell Signaling Technology MEK1 antibody (Cell Signalling Technology, 9154) was used in western blot on human samples at 1:1000 (fig  6). Cell Signal (2015) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9121) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 9121) was used in western blot on human samples. J Thyroid Res (2014) ncbi
rabbit polyclonal
  • WB; human; 1:1000; fig 4
In order to report that Koelreuteria formosana ethanolic extract inhibits the invasion and migration of renal cell carcinoma cells, Cell Signaling Technology MEK1 antibody (Cell Signaling, 9121) was used in western blot on human samples at 1:1000 (fig 4). Mol Med Rep (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1:100; fig 1
In order to investigate how BRAF/MAPK activity regulates intestinal stem cell populations and contributes to colon cancer, Cell Signaling Technology MEK1 antibody (Cell Signaling, 9121) was used in western blot on mouse samples at 1:100 (fig 1). Oncogene (2015) ncbi
rabbit monoclonal (41G9)
  • WB; rat
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9154) was used in western blot on rat samples. Int J Mol Med (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signalling, 9154) was used in western blot on human samples. Cell Microbiol (2014) ncbi
mouse monoclonal (61B12)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 2352) was used in western blot on human samples. Mol Biol Cell (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 9154) was used in western blot on human samples. Mol Biol Cell (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9154) was used in western blot on human samples. Cell Death Dis (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human; 1:1000
Cell Signaling Technology MEK1 antibody (Cell Signaling, #9154P) was used in western blot on human samples at 1:1000. J Mol Histol (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 9154) was used in western blot on human samples. Pigment Cell Melanoma Res (2014) ncbi
rabbit monoclonal (41G9)
  • WB; mouse; 1:1000
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9154) was used in western blot on mouse samples at 1:1000. Biochim Biophys Acta (2014) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 9154) was used in western blot on human samples. Cancer Res (2013) ncbi
rabbit monoclonal (41G9)
  • WB; human
Cell Signaling Technology MEK1 antibody (Cell Signaling, 9154S) was used in western blot on human samples. J Biol Chem (2013) ncbi
rabbit polyclonal
  • WB; human; 1:1000
In order to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes, Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9121) was used in western blot on human samples at 1:1000. Arch Dermatol Res (2014) ncbi
rabbit monoclonal (41G9)
  • WB; mouse
Cell Signaling Technology MEK1 antibody (Cell Signaling Technology, 9154) was used in western blot on mouse samples. PLoS ONE (2013) ncbi
not indicated
  • FC; human
  • IHC; human
Cell Signaling Technology anti-MEK1 antibody was used to perform flow cytometry and immunochemistry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10.J Immunol (2010) ncbi
not indicated
  • WB; human
  • FC; human
Cell Signaling Technology anti-MEK1/2 antibody was used to perform western blot and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10.J Immunol (2010) ncbi
not indicated
  • WB; human
  • IP; human
Cell Signaling Technology anti-MEK1 and anti-phospho-MEK1 antibodies were used in western blot and immunoprecipitation in order to study the role of Beclin 1 in the regulation of autophagy.J Biol Chem (2009) ncbi
not indicated
  • WB; human
Cell Signaling anti-phospho-MEK antibody was used for western blot in order to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway.Proc Natl Acad Sci U S A (2009) ncbi
not indicated
  • WB; human
Cell Signaling anti-total MEK and anti-phospho-MEK antibodies were used in western blot to test the hypothesis that additional RAS mutations outside of codons 12, 13, and 61 may account for oncogenesis in myeloid malignancies.Blood (2009) ncbi
not indicated
  • WB; human
Cell Signaling anti-phospho-MEK1/2 was used to perform western blot in order to show that MEK1 or MEK2 activation is sufficient for metastatic tumor formation.BMC Cancer (2008) ncbi
not indicated
  • WB; human
Cell Signaling anti-p-MEK1 antibody was used in western blot to study the role for Hsp72 in suppression of the oncogene-induced senescence.Mol Cell Biol (2009) ncbi
not indicated
  • WB; human
Cell Signaling Technology MEK1/2 antibody was used in western blot in order to show that Hsp90 co-chaperone CDC37 can maintain the oncogenic protein kinase clients.Oncogene (2009) ncbi
not indicated
  • WB; human
Cell Signaling Technology anti-Mek1/2 antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation.Neoplasia (2008) ncbi
not indicated
  • WB; human
Cell Signaling Technology ERK phospho-MEK antibody was used in western blot in order to study the role of PAX4 in the beta-cell differentiation of human embryonic stem cellsPLoS ONE (2008) ncbi
not indicated
  • WB; human
Cell Signaling Technology anti-MEK1 and anti-phospho-MEK1 (Ser217/221) antibodies were used in human 1HAEo cell line and in western blot to study the link between the PI3K-Akt pathway and the cigarette smoke (CS) stimulated epidermal growth factor receptor-mediated FRA-1 induction in non-oncogenic HBE cells.J Biol Chem (2006) ncbi
not indicated
  • WB; human
Cell Signaling Technology anti-phospho-MEK antibody was used in western blot to study heterogeneous de novo missense mutations in three genes within the mitogen-activated protein kinase (MAPK) pathway.Science (2006) ncbi
not indicated
  • WB; human
Cell Signaling anti-MEK1/2 was used in western blot to detect MEK expression and MEK phosphorylation status in human A549 lung adenocarcinoma cells.J Biol Chem (2006) ncbi
not indicated
  • WB; human
Cell Signaling anti-phospho-MEK1 antibody was used in western blot to detect phospho-MEK1 in HT-29 cells treated with NMT1-1 siRNA or NMT2-4 siRNA.Mol Cancer Res (2005) ncbi
not indicated
  • EMSA; human
Cell Signaling anti-phospho-MEK1/2 (Ser-217/221) antibody was used to investigate the activation of Erk1/2 by intracellular M. lepraeProc Natl Acad Sci U S A (2005) ncbi
not indicated
  • WB; human
  • IC; human
Cell Signaling pMEK1/2 polyclonal antibody was used to investigate the role of GIT1 in ERK1/2 activation during focal adhesionsJ Biol Chem (2005) ncbi
not indicated
  • WB; human
Cell Signaling Technology polyclonal anti-phospho-MEK1/2 and anti-MEK1/2 antibodies were used in human umbilical vein endothelial cells (HUVECs) and in western blot to study the effect of enhanced p38 MAPK activity on endothelial cell function.J Biol Chem (2005) ncbi
not indicated
  • WB; human
Cell Signaling anti-p-MEK1/2 (no. 9121S) antibody was used in Western blot to study the biological function of TRAIL induced apoptosis in human colon cells.J Biol Chem (2005) ncbi
Promega
rabbit polyclonal
  • WB; rat; 1:500
Promega MEK1 antibody (Promega, V803A) was used in western blot on rat samples at 1:500. Cell Death Dis (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:2000
Promega MEK1 antibody (Promega, V8031) was used in western blot on mouse samples at 1:2000. J Cell Physiol (2015) ncbi
rabbit polyclonal
  • WB; mouse
Promega MEK1 antibody (Promega, V8031) was used in western blot on mouse samples. Am J Physiol Gastrointest Liver Physiol (2015) ncbi
rabbit polyclonal
  • WB; rat
Promega MEK1 antibody (Promega, V803A) was used in western blot on rat samples. PLoS ONE (2014) ncbi
rabbit polyclonal
  • WB; mouse
Promega MEK1 antibody (Promega, V8031) was used in western blot on mouse samples. PLoS ONE (2014) ncbi
rabbit polyclonal
  • WB; human
Promega MEK1 antibody (Promega Biotech AB, V803A) was used in western blot on human samples. J Biol Chem (2014) ncbi
rabbit polyclonal
  • IHC; mouse
In order to , Promega MEK1 antibody (Promega, V8031) was used in immunohistochemistry on mouse samples. J Biol Chem (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse
Promega MEK1 antibody (Promega, V803A) was used in immunohistochemistry - frozen section on mouse samples. Neurobiol Dis (2013) ncbi
Dako
not indicated
  • WB; human
Cell Signaling Technology rabbit polyclonal anti-MAP kinase p44/p42 antibody was used to perform westn blot in order to investigate the relations between TGFbeta1 and TNFa.Mol Biol Cell (2009) ncbi
BD Biosciences
mouse monoclonal (25/MEK1)
  • WB; human
BD mouse anti-MEK1 antibody (catalog no:610122) was used in western blot to combine computational simulations, experimental testing of simulation results, and finally reverse engineering of a protein interaction network to define potential therapeutic strategies for de novo trastuzumab resistant breast cancerBMC Syst Biol (2009) ncbi
not indicated
  • WB; human
Transduction Laboratories anti-MEK1 was used to perform western blot in order to show that MEK1 or MEK2 activation is sufficient for metastatic tumor formation.BMC Cancer (2008) ncbi
Sigma-Aldrich
not indicatedSigma PD98959 (mitogen activated protein kinase kinase 1 [MEK1] inhibitor) was used to treat cells in order to investigate the relationship between TGF-beta1 and IL-6 in human trabecular meshwork cells.Mol Vis (2009) ncbi
not indicatedSigma mitogen-activated protein kinase 1 (MEK1) was used to treat cells in order to study the role for protein kinase signaling in HCV infectionJ Virol (2008) ncbi
Articles Reviewed
  1. Rodica P Bunaciu et al. (2015). "6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells".PMID 26287494
  2. Havovi Chichger et al. (2015). "Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling".PMID 26254426
  3. Björn Koos et al. (2015). "Proximity-dependent initiation of hybridization chain reaction".PMID 26065580
  4. Adriaan H de Wilde et al. (2015). "A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins".PMID 26041291
  5. Xun Tang et al. (2015). "CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells".PMID 26004137
  6. Jonathan Rios-Doria et al. (2015). "A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways".PMID 25948294
  7. Y Yu et al. (2015). "Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation".PMID 25941817
  8. Alexander Brobeil et al. (2015). "PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway".PMID 25893721
  9. Ming wei Bao et al. (2015). "Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction".PMID 25840773
  10. Toshiaki Tanaka et al. (2015). "Sec8 regulates cytokeratin8 phosphorylation and cell migration by controlling the ERK and p38 MAPK signalling pathways".PMID 25725287
  11. Artur Wnorowski et al. (2015). "Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells".PMID 25703025
  12. M Curcio et al. (2015). "Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons".PMID 25675305
  13. Jicui Chen et al. (2015). "TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes".PMID 25655684
  14. Hoi Yee Chow et al. (2015). "Group I Paks as therapeutic targets in NF2-deficient meningioma".PMID 25596744
  15. Lawrence A Scheving et al. (2015). "Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice".PMID 25414100
  16. Osamu Tohyama et al. (2014). "Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models".PMID 25295214
  17. Chin Yin Lin et al. (2014). "Inhibition of the invasion and migration of renal carcinoma 786‑o‑si3 cells in vitro and in vivo by Koelreuteria formosana extract".PMID 25241754
  18. P Riemer et al. (2015). "Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity".PMID 25109331
  19. Xin Yi et al. (2014). "Hepatocyte growth factor regulates the TGF-β1-induced proliferation, differentiation and secretory function of cardiac fibroblasts".PMID 24840640
  20. Vernat Exil et al. (2014). "Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures".PMID 24787138
  21. Tyson P Eucker et al. (2014). "The focal complex of epithelial cells provides a signalling platform for interleukin-8 induction in response to bacterial pathogens".PMID 24779413
  22. Q Wang et al. (2015). "Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis".PMID 24632605
  23. Douglas A Chapnick et al. (2014). "Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets".PMID 24623725
  24. Robert Linke et al. (2014). "The MEK1/2-ERK1/2 pathway is activated in chronic rhinosinusitis with nasal polyps".PMID 24609540
  25. Dov B Ballak et al. (2014). "MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice".PMID 24586913
  26. Jean Philippe Guegan et al. (2014). "MEK1/2 overactivation can promote growth arrest by mediating ERK1/2-dependent phosphorylation of p70S6K".PMID 24501087
  27. John R Grünberg et al. (2014). "The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT".PMID 24451367
  28. Y Sun et al. (2014). "Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells".PMID 24384722
  29. Subhasree Basu et al. (2014). "α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation".PMID 24381169
  30. Zhiwei Wang et al. (2014). "Angiotensin-II induces phosphorylation of ERK1/2 and promotes aortic adventitial fibroblasts differentiating into myofibroblasts during aortic dissection formation".PMID 24343777
  31. Jaehyuk Choi et al. (2014). "Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors".PMID 24283590
  32. Yan Zhang et al. (2014). "Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction".PMID 24275554
  33. Barbara S Paugh et al. (2013). "Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas".PMID 23970477
  34. Yanping Li et al. (2013). "Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation".PMID 23893412
  35. Elina Siljamäki et al. (2014). "p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes".PMID 23856837
  36. Yan Ping Zhang et al. (2013). "Diabetic neuropathic pain development in type 2 diabetic mouse model and the prophylactic and therapeutic effects of coenzyme Q10".PMID 23684663
  37. Jia Dai et al. (2013). "IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis".PMID 23349709
  38. Qiaoling Liang et al. (2010). "IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma".PMID 20926789
  39. Yi Xiang et al. (2010). "GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking".PMID 20083603
  40. Jianrong Wang et al. (2009). "A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1".PMID 19520853
  41. Xiaoying Liu et al. (2009). "Transforming growth factor beta1-mediated activation of the smooth muscle alpha-actin gene in human pulmonary myofibroblasts is inhibited by tumor necrosis factor-alpha via mitogen-activated protein kinase kinase 1-dependent induction of the Egr-1 transcr".PMID 19261809
  42. Christine A Pratilas et al. (2009). "(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway".PMID 19251651
  43. Paloma B Liton et al. (2009). "Cross-talk between TGF-beta1 and IL-6 in human trabecular meshwork cells".PMID 19209241
  44. Ozgur Sahin et al. (2009). "Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance".PMID 19118495
  45. Jeffrey W Tyner et al. (2009). "High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients".PMID 19075190
  46. Laure Voisin et al. (2008). "Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors".PMID 19014680
  47. Vladimir L Gabai et al. (2009). "Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells".PMID 19001088
  48. J R Smith et al. (2009). "Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors".PMID 18931700
  49. Michelle J Farquhar et al. (2008). "Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity".PMID 18579596
  50. Tushar B Deb et al. (2008). "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation".PMID 18562482
  51. Yelena Lyustikman et al. (2008). "Constitutive activation of Raf-1 induces glioma formation in mice".PMID 18472967
  52. Takashi Nakakuki et al. (2008). "Topological analysis of MAPK cascade for kinetic ErbB signaling".PMID 18335053
  53. Binhui Wu et al. (2008). "Proteomics analysis of immunoprecipitated proteins associated with the oncogenic kinase cot".PMID 18319612
  54. Sarah Chapelsky et al. (2008). "Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol".PMID 18183301
  55. Qin Zhang et al. (2006). "A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression".PMID 16490785
  56. Pablo Rodriguez-Viciana et al. (2006). "Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome".PMID 16439621
  57. Anna Moshnikova et al. (2006). "The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway".PMID 16421102
  58. Charles E Ducker et al. (2005). "Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis".PMID 16123142
  59. Nikos Tapinos et al. (2005). "Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli".PMID 15967991
  60. Guoyong Yin et al. (2005). "GIT1 is a scaffold for ERK1/2 activation in focal adhesions".PMID 15923189
  61. Juan Wang et al. (2005). "Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway".PMID 15849192
  62. Meghan E McMullen et al. (2005). "Activation of p38 has opposing effects on the proliferation and migration of endothelial cells".PMID 15790570
  63. Konstantinos G Drosopoulos et al. (2005). "Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway".PMID 15757891