This is a review about IL-18, based on 7 published articles (read how Labome selects the articles), using IL-18 antibody in all methods. It is aimed to help Labome visitors find the most suited IL-18 antibody.
IL-18 synonym: IGIF; IL-18; IL-1g; IL1F4; IFN-gamma-inducing factor; IL-1 gamma; iboctadekin; interleukin-1 gamma; interleukin-18

R and D SystemsR and D Systems IL-18 product
  • block or activateIn 2004, Bysani Chandrasekar et al. applied R and D Systems IL-18 antibody to study the proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death [ncbi , more ].
Life Technologies CorporationLife Technologies Corporation IL-18 product
  • ELISAIn 2005, Ozer Arican et al. applied Life Technologies Corporation IL-18 antibody to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology IL-18 product
  • immunoprecipitationIn 2002, P V Sivakumar et al. employed Santa Cruz Biotechnology IL-18 antibody to study the role of IL-18 in contributing to the pathology of IBD [ncbi , more ].
  • western blotP V Sivakumar et al. employed Santa Cruz Biotechnology IL-18 antibody to study the role of IL-18 in contributing to the pathology of IBD [ncbi , more ] in 2002 and Anne Corbaz et al. used Santa Cruz Biotechnology IL-18 antibody to study the expression of IL-18-binding protein in active Crohn s disease [ncbi , more ].
MBL International
  • immunocytochemistryIn 2007, Hitomi Seino et al. utilized MBL International IL-18 antibody to study the role of IL-18 in the formation of stress-induced, histamine-dependent gastric lesions [ncbi , more ].
  • western blotIn 2007, Hitomi Seino et al. utilized MBL International IL-18 antibody to study the role of IL-18 in the formation of stress-induced, histamine-dependent gastric lesions [ncbi , more ].
MD BIOSCIENCES
  • immunohistochemistryIn 2008, C A Wijbrandts et al. applied IL-18 antibody to determine whether the heterogeneous clinical response to tumour necrosis factor (TNF) alpha blocking therapy in rheumatoid arthritis (RA) can be predicted by TNFalpha expression in the synovium before initiation of treatment [ncbi , more ].
BioVision
  • western blotIn 2008, Sarah Chapelsky et al. applied BioVision IL-18 antibody to demonstrate that celastrol inhibits lethal toxin-induced death of RAW264.7 murine macrophages [ncbi , more ].
Articles Reviewed
  1. Sarah Chapelsky et al. (2008). "Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol".PMID 18183301
  2. C A Wijbrandts et al. (2008). "The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium".PMID 18055470
  3. Hitomi Seino et al. (2007). "IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions".PMID 16959946
  4. Ozer Arican et al. (2005). "Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity".PMID 16258194
  5. Bysani Chandrasekar et al. (2004). "Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death".PMID 14960579
  6. P V Sivakumar et al. (2002). "Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage".PMID 12010883
  7. Anne Corbaz et al. (2002). "IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease".PMID 11907126