This is a review about IKK alpha, based on 41 published articles (read how Labome selects the articles), using IKK alpha antibody in experiments. It is aimed to help Labome visitors find the most suited IKK alpha antibody.
IKK alpha synonym: IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16; I-kappa-B kinase 1; I-kappa-B kinase-alpha; IKK-a kinase; IkB kinase alpha subunit; Nuclear factor NFkappaB inhibitor kinase alpha; TCF-16; inhibitor of nuclear factor kappa-B kinase subunit alpha; transcription factor 16

  • Santa Cruz Biotechnology anti-IKKalpha monoclonal antibody was used to perform western blot in order to study that cleveage of NIK leads to noncanonical NF- kB activation (catalog: sc-949) ncbi, more
  • suppliernumreagent linkcited catalog
    Santa Cruz Biotechnology26IKK alpha antibodySC-7182, sc-7606, SC-7184, sc-847, sc-949
    EMD Millipore1IKK alpha antibody
    WILEX Inc.1
    Cell Signaling Technology10IKK alpha antibody
    BD Biosciences4
    GE Healthcare Life Biosciences1
    Table 1. IKK alpha antibody western blot.
  • Santa Cruz anti-IKK alpha was used to perform western blot in order to show that Skp2 phosphorylation by Akt1 promotes Skp2 to localize in cytoplasm and impairs APCCdh1-mediated Skp2 destruction (catalog: SC-7184) ncbi, more
  • Santa Cruz Biotechnology IKKalpha antibody was used in western blot in order to demonstrate that CARD11 can recruit signaling cofactors independently of one another in a signal-inducible manner. (catalog: sc-7606) ncbi, more
  • Santa Cruz antibody against I kappa B alpha was used in western blot to study the inhibition effect of sphingosine-1-phosphate on nuclear factor kappa B activation and germ cell apoptosis in the human testis independently of its receptors (catalog: sc-847) ncbi, more
  • Santa Cruz Biotechnology IKKalpha antibody (SC-7182) was used in western blot to study the effect of human herpes virus 8-encoded viral FLICE inhibitory protein on Ikappa B kinase complex (catalog: SC-7182) ncbi, more
  • Santa Cruz Biotechnology IKKa/b antibody (H-470) was used to perform western blot in order to indicate an important role for the ubiquitin ligase activity of HOIP in CD40 signaling.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology5IKK alpha antibody
    Cell Signaling Technology1IKK alpha antibody
    Table 2. IKK alpha antibody immunoprecipitation.
  • Santa Cruz IKBKA antibody was used in chromatin immunoprecipitation in order to identify NF-kappaB target genes involved in thyroid cancerncbi, more
  • Santa Cruz Biotechnologies IKKalpha antibody was used in western blot in order to demonstrate that NF-kappaB dictates the degradation pathway of IkappaBalphancbi, more
  • Santa Cruz Biotechnology anti-IKKalphabeta and anti-phospho-IKKalphabeta antibodies were used in western blot to study the role of TLR2 in CCL5 secretion in response to M. bovis BCG.ncbi, more
  • Santa Cruz IkB antibody was used in western blot to investigate the effect of TA on early inflammation and vascular leakage in the retina of STZ-induced hyperglycemic rats.ncbi, more
  • Santa Cruz Biotechnology IKK alpha antibody was used in immunoprecipitation to study the K13-induced NF-B and JNK activation and re-examine the role of TRAFs in these processes.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology3IKK alpha antibody
    Table 3. IKK alpha antibody immunohistochemistry.
  • Santa Cruz rabbit anti-IKKalpha antibody was used in western blot to detect IKKalpha in the PAK4 knockdown cells treated with TNFalpha+CHX.ncbi, more
  • Santa Cruz Biotechnology IKK alpha antibody was used in western blot to study I{kappa}B kinase signaling regulated by PP2Ancbi, more
  • Santa Cruz Biotechnology I kappa B alpha antibody was used in western blot to study the role of endothelin-1 in increaseing total peripheral resistance (TPR) and decreaseing organ blood flow.ncbi, more
  • SCBT IKK alpha /beta antibody was used in western blot to characterize a NIK and IKKbeta binding proteinncbi, more
  • Santa Cruz Biotechnology antibody to I kappa B alpha was used in western blot to study the coactivators and corepressors of NF-kappa B in I kappa B alpha gene promoterncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1IKK alpha antibody
    Table 4. IKK alpha antibody ChIP assay.
  • Santa Cruz Biotechnology anti-IKK alpha antibody was used in immunoprecipitation to study tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cellsncbi, more
  • Santa Cruz Biotechnology anti-IKKalpha antibody was used in human cells and in western blot, immunoprecipitation to study the role for hTid-1 in the regulation of NF-kappaB activity and suppression of tumor growth.ncbi, more
  • Santa Cruz Biotechnology anti-IKKalpha antibody was used in western blot to study the effect of tumor necrosis factor alpha receptor complex-targeted MEKK3 on NF-kappaB in receptor-interacting protein-deficient cells.ncbi, more
  • Santa Cruz anti-IKKalpha antibody (H-744) was used in human HeLa cells, HEK293 IL-1R cells and in western blot, immunoprecipitation to study the effect of multiple protein kinases and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription on constitutive and interleukin-1-inducible phosphorylation of p65 NF- B at serine 536.ncbi, more
  • Santa Cruz Biotechnology IKK alpha antibody was used in western blot to study precise mechanism by which TGase 2 promotes inflammation.ncbi, more
  • suppliernumreagent link
    Santa Cruz Biotechnology1IKK alpha antibody
    Table 5. IKK alpha antibody immunocytochemistry.
  • Santa Cruz Biotech IkappaB-alpha polyclonal antibody (PAb-sc-371) was used in immunohistochemistry to study the expression pattern of NFkappaB family members in human melanocytic cells of normal skin, benign intradermal naevus, and metastatic melanoma tissues.ncbi, more
  • Santa Cruz Biotechnology anti-IKKalpha/beta antibody sc-7607 was used in western blot to study the role of RelB serine 368 for dimerization and p100 stabilization.ncbi, more
  • Santa Cruz Biotechnologies anti-IKKalpha antibody (H-744) was used in HeLa (A) cells and in western blot to study the regulatory mechanisms for the phosphorylation of p65 on Ser-536 under physiological conditions.ncbi, more
  • Santa Cruz Biotechnology antibody against human I-kappa-B-alpha that contains the phosphorylated Ser-32 amino acid was used in western blot to study the induction of ICAM-1 expression in human aortic endothelial cells by Chlamydophila pneumoniae via protein kinase C dependent activation of nuclear factor-kappa Bncbi, more
  • Santa Cruz Biotechnology polyclonal IKK alpha antibody was used in western blot to study the role of IKK alpha in mitogenic signalingncbi, more
  • Santa Cruz Biotechnology anti-IKK1 antibody (sc-7182) was used in human HepG2 cells and in western blot, immunoprecipitation to study the effect of inhibitor kappaB kinase complex on insulin receptor substrate 1.ncbi, more
  • Santa Cruz mouse monoclonal anti-IKKalpha antibody B-8 was used in cultured human cells and biopsied lymph nodes and in immunohistochemistry, immunocytochemistry to study the intracellular localization of tumor necrosis factor (TNF) receptor associated factor (TRAF) proteins in H-RS cells.ncbi, more
  • Santa Cruz polyclonal anti-IKK antibody (H-744) was used in western blot to study the formation of the TRAF6-TAB2-TAK1 complex.ncbi, more
  • Santa Cruz Biotechnology anti-IKKalpha antibody was used in western blot to study the role of TRAF2 and TRAF5 in tumor necrosis factor-induced NF- B activation and protection from cell death.ncbi, more
  • Santa Cruz Biotechnology anti IkappaBalpha antibody was used in western blot to study the function of FLASH in NF-kappaB Activity.ncbi, more
  • Upstate Biotechnology anti-phospho-IKKalpha antibody was used in western blot to study the phosphorylation of IKKalpha.ncbi, more
WILEX Inc.
  • Oncogene monoclonal Anti-IKK was used to perform western blot in order to prove that the catalytic activity of IKK modified with O-GlcNAc in p53-deficient cells is enhanced.ncbi, more
  • Cell Signaling rabbit anti-pIKKalpha antibody was used to perform western blot in order to study the role of F.n. induced MiR-155 in enhanced pro-inflammatory cytokine response and SHIP down-regulation.ncbi, more , figure 1
  • Figure 1
    IKK alpha antibody western blot Cell Signaling Technology
    IKK alpha antibody western blot Cell Signaling Technology
    Cell lysates from WT and TLR2 macrophage mutants infected with F. tularensis novicida for various time were analyzed by Western blotting for pIKKalpha, pNFkappaBp65, and actin.
    Thomas J Cremer et al. (2009). "MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response".PMID 20041145
  • Cell Signaling rabbit anti-phospho-IKK-alpha/beta was used to perform western blotting in order to determine the role of NRAGE in regulating NF-kappaB activity.ncbi, more
  • Cell Signaling Biotechnology IKKalpha antibody was used in western blot to study the regulation of aromatase transcription and estrogen biosynthesis in adipose stromal cells (ASCs).ncbi, more
  • Cell Signaling Technology anti-IKBKA antibody was used to carry out western blot analysis in order to examine whether insulin-resistant patients have abnormal TLR4 expression and TLR4-driven signaling in skeletal muscle.ncbi, more
  • Cell Signaling anti-phospho-IkappaB antibody was used in western blot to study inhibition of MAPK and NFkappaB signaling pathways through preventing activation of the family of MAPK kinases (MAPKK).ncbi, more
  • Cell Signaling Technology phospho-specific IKK alpha (Ser-180) antibody was used in western blot to study I{kappa}B kinase signaling regulated by PP2Ancbi, more
  • Cell Signaling phospho-IKK alpha /beta antibody was used in western blot to characterize a NIK and IKKbeta binding proteinncbi, more
  • Cell Signaling Technology anti-IKKalpha and anti-Phospho-IKKalpha (Ser180) /IKKbeta (Ser181) were used in western blot to detect total IKKalpha and activated IKKalpha/beta in human Reh and HEK 293 cells.ncbi, more
  • Cell Signaling Technologies I-kappa B alpha antibody was used in western blot to study precise mechanism by which TGase 2 promotes inflammation.ncbi, more
  • Cell Signaling Technology anti-IKKalpha antibody was used in immunoprecipitation to study the phosphorylation of IKKalpha.ncbi, more
  • Cell Signaling anti-phospho-IKK antibody was used in western blot to study the phosphorylation of IKK.ncbi, more
BD Biosciences
  • Pharmingen IKK alpha antibody (1:1000) was used to perform western blot in order to study the funtion of phosphorylation of gamma-binding domain of IkB kinase beta.ncbi, more
  • Pharmingen IKK alpha antibody was used in western blot to study I{kappa}B kinase signaling regulated by PP2Ancbi, more
  • Pharmingen mouse anti-IKK alpha antibody was used in western blot to study tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cellsncbi, more
  • PharMingen monoclonal IKK alpha antibody was used in western blot to study the role of IKK alpha in mitogenic signalingncbi, more
GE Healthcare Life Biosciences
  • Amersham Biosciences anti-IKKalpha and anti-Phospho-IKKalpha (Ser180) /IKKbeta (Ser181) were used in western blot to detect total IKKalpha and activated IKKalpha/beta in human Reh and HEK 293 cells.ncbi, more
Articles Reviewed
  1. Shaun Rosebeck et al. (2011). "Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation".PMID 21273489
  2. Bruce S Hostager et al. (2010). "HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex".PMID 20614026
  3. Nicholas Matluk et al. (2010). "A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway".PMID 20100315
  4. Thomas J Cremer et al. (2009). "MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response".PMID 20041145
  5. DaMing Gao et al. (2009). "Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction".PMID 19270695
  6. Sagar Ghosh et al. (2009). "IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells".PMID 19221050
  7. Keiko Kawauchi et al. (2009). "Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification".PMID 19202066
  8. Tomoyasu Higashimoto et al. (2008). "Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1".PMID 18957422
  9. Alessio Iannetti et al. (2008). "The neutrophil gelatinase-associated lipocalin (NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells".PMID 18768801
  10. Sara M Reyna et al. (2008). "Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects".PMID 18633101
  11. Ryan R McCully et al. (2008). "The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association".PMID 18625728
  12. Erika Mathes et al. (2008). "NF-kappaB dictates the degradation pathway of IkappaBalpha".PMID 18401342
  13. Patricia Méndez-Samperio et al. (2008). "Mycobacterium bovis bacillus Calmette-Guerin induces CCL5 secretion via the Toll-like receptor 2-NF-kappaB and -Jun N-terminal kinase signaling pathways".PMID 17989335
  14. Y H Kim et al. (2007). "Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage".PMID 17881007
  15. Hittu Matta et al. (2007). "Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation".PMID 17597077
  16. Sohini Mukherjee et al. (2006). "Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation".PMID 16728640
  17. Xiaofan Li et al. (2005). "PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor".PMID 16227624
  18. Arlene E Kray et al. (2005). "Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A".PMID 16126728
  19. Rongqian Wu et al. (2005). "Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1".PMID 16018991
  20. Wen Hui Hu et al. (2005). "NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation".PMID 15951441
  21. Zhanguo Gao et al. (2005). "Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter".PMID 15811852
  22. Laura Suomalainen et al. (2005). "Sphingosine-1-phosphate inhibits nuclear factor kappaB activation and germ cell apoptosis in the human testis independently of its receptors".PMID 15743789
  23. Ling Chi Wang et al. (2005). "Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK".PMID 15611081
  24. Hua Cheng et al. (2005). "Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth".PMID 15601829
  25. Marzenna Blonska et al. (2004). "Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells".PMID 15572679
  26. Holger Buss et al. (2004). "Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK".PMID 15489227
  27. Andrew M F Liu et al. (2004). "G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling".PMID 15485865
  28. Jongmin Lee et al. (2004). "Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia".PMID 15471861
  29. Susan E McNulty et al. (2004). "Comparative expression of NFkappaB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies".PMID 15016307
  30. Harald Jakob Maier et al. (2003). "Critical role of RelB serine 368 for dimerization and p100 stabilization".PMID 12874295
  31. Hiroaki Sakurai et al. (2003). "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway".PMID 12842894
  32. Silvana A Vielma et al. (2003). "Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB".PMID 12714566
  33. Chris Albanese et al. (2003). "IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf".PMID 12589056
  34. Zhanguo Gao et al. (2002). "Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex".PMID 12351658
  35. Kaoru Saijo et al. (2002). "Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha".PMID 12070292
  36. Christopher J Howe et al. (2002). "Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytes".PMID 12063265
  37. Ryouichi Horie et al. (2002). "Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells".PMID 12000717
  38. Li Liu et al. (2002). "The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex".PMID 11830587
  39. Junko Mizukami et al. (2002). "Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6".PMID 11809792
  40. K Tada et al. (2001). "Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death".PMID 11479302
  41. Y H Choi et al. (2001). "FLASH coordinates NF-kappa B activity via TRAF2".PMID 11340079