This is a review about HNF4A, based on 32 published articles (read how Labome selects the articles), using HNF4A antibody in all methods. It is aimed to help Labome visitors find the most suited HNF4A antibody.
HNF4A synonym: FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14; HNF4alpha10/11/12; TCF-14; hepatic nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; nuclear receptor subfamily 2 group A member 1; transcription factor 14; transcription factor HNF-4

Santa Cruz Biotechnology
goat polyclonal (C-19)
  • IHC-P; mouse
In order to elucidate the origin of hepatocellular carcinoma, Santa Cruz Biotechnology HNF4A antibody (Santa, sc-6556) was used in immunohistochemistry - paraffin section on mouse samples. J Clin Invest (2015) ncbi
goat polyclonal (C-19)
  • FC; human
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in flow cytometry on human samples. Stem Cell Res Ther (2015) ncbi
rabbit polyclonal (H-171)
  • IC; human; tbl 2
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-8987) was used in immunocytochemistry on human samples (tbl 2). Exp Cell Res (2015) ncbi
goat polyclonal (C-19)
  • IHC; mouse; 1:600; tbl 2
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in immunohistochemistry on mouse samples at 1:600 (tbl 2). Dev Biol (2015) ncbi
goat polyclonal (C-19)
  • IHC-P; mouse; 1:50
In order to investigate the role of transcription factors SOX4 and SOX9 during the development of bile ducts, Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. Dev Biol (2015) ncbi
rabbit polyclonal (H-171)
  • ChIP; mouse
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz Biotechnology, sc-8987) was used in chromatin immunoprecipitation on mouse samples. Biochim Biophys Acta (2015) ncbi
goat polyclonal (C-19)
  • WB; mouse; 1:500
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz Biotechnology, sc-6556) was used in western blot on mouse samples at 1:500. Biochim Biophys Acta (2015) ncbi
goat polyclonal (C-19)
  • IC; human; 1:600; tbl 1
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in immunocytochemistry on human samples at 1:600 (tbl 1). Methods Mol Biol (2016) ncbi
rabbit polyclonal (H-171)
  • ChIP-Seq; human
  • ChIP; human
  • IP; human
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz Biotechnology, sc-8987) was used in ChIP-Seq on human samples, in chromatin immunoprecipitation on human samples, and in immunoprecipitation on human samples. J Biol Chem (2015) ncbi
goat polyclonal (C-19)
  • IHC-P; mouse
  • WB; mouse
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, SC-6556) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples. PLoS ONE (2014) ncbi
rabbit polyclonal (H-171)
  • ChIP; rat
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz Biotechnology, sc-8987) was used in chromatin immunoprecipitation on rat samples. FASEB J (2014) ncbi
goat polyclonal (C-19)
  • IC; human
In order to study the effect of HNF4alpha on the chemosensitivity to oxaliplatin and 5-FU in renal cell carcinoma, Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in immunocytochemistry on human samples. J Pharm Sci (2014) ncbi
rabbit polyclonal (H-171)
  • IHC-P; mouse; 1:200
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, SC-8987) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. Springerplus (2014) ncbi
rabbit polyclonal (H-171)
  • IC; human; 1:50
Santa Cruz Biotechnology HNF4A antibody (Santa-Cruz, sc-8987) was used in immunocytochemistry on human samples at 1:50. Acta Naturae (2014) ncbi
rabbit polyclonal (H-171)
  • IC; mouse; 1:100
In order to investigate the role of fgfr/erk signalling in the formation of a polarised primitive endoderm layer in embryoid bodies, Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, H-171) was used in immunocytochemistry on mouse samples at 1:100. PLoS ONE (2014) ncbi
goat polyclonal (C-19)
  • IC; human; 1:100
In order to evaluate a culture method for the maturation of induced pluripotent stem cell derived hepatocytes, Santa Cruz Biotechnology HNF4A antibody (SantaCruz, sc6556) was used in immunocytochemistry on human samples at 1:100. PLoS ONE (2014) ncbi
goat polyclonal (C-19)
  • ChIP; human; fig 4
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz Biotechnology Inc, sc- 6556) was used in chromatin immunoprecipitation on human samples (fig 4). PLoS ONE (2014) ncbi
rabbit polyclonal (H-171)
  • WB; human
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, Sc-8987X) was used in western blot on human samples. J Virol (2014) ncbi
goat polyclonal (C-19)
  • IHC; mouse; 1:100
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc6556) was used in immunohistochemistry on mouse samples at 1:100. PLoS ONE (2013) ncbi
goat polyclonal (C-19)
  • EMSA; human
  • ChIP; human
  • WB; human
Santa Cruz Biotechnology HNF4A antibody (Santa Cruz, sc-6556) was used in EMSA on human samples, in chromatin immunoprecipitation on human samples, and in western blot on human samples. Biochim Biophys Acta (2013) ncbi
rabbit polyclonal (H-171)
  • ChIP; human
Santa Cruz anti-HNF4 alpha antibody was used to perform ChIP assays in order to study the roles of PXR in the regulations of CYP4F12 and the coactivation and corepression to a broad range of promoters.Nucleic Acids Res (2009) ncbi
goat polyclonal (C-19)
  • IHC; human
Santa Cruz anti-HNF4alpha antibody (1:500) was used in immunohistochemistry in order to study roles of GATA4 and GATA6 in controlling the onset of cardiac myocyte differentiationDev Biol (2008) ncbi
not indicated
  • WB; human
  • IHC; human
Santa Cruz Biotechnology HNF4alpha antibody (1:500) was used in western blot in order to study the role of HNF4alpha in the gut and in the pathogenesis of inflammatory bowel disease (IBD)Inflamm Bowel Dis (2008) ncbi
not indicated
  • WB; human
  • IP; human
  • ChIP; human
Santa Cruz Biotechnology anti-HNF4alpha antibody was used in immunoprecipitation to isolate HNF4alpha from primary human hepatocytes, in western blot to detect HNF4alpha in primary human hepatocytes, and in CHIP assay to investigate the binding of Prox1 to the human CYP7A1 gene in human HepG2 cells.J Biol Chem (2006) ncbi
goat polyclonal (C-19)
  • ChIP; human
Santa Cruz Biotechnology goat anti-HNF4alpha (C-19) antibody was used in ChIP assay to study the role of PXR crosstalk with HNF4alpha and co-activators, and suppression of SHP gene expression in the rifampicin induction of CYP3A4.Drug Metab Dispos (2006) ncbi
not indicated
  • EMSA; human
  • ChIP; human
Santa Cruz anti-HNF-4 alpha antibody was used in EMSA and ChIP assay to study transcriptional regulation of human microsomal triglyceride transfer proteinJ Lipid Res (2005) ncbi
R and D Systems
mouse monoclonal (H1415)
  • IHC-P; mouse
In order to elucidate the origin of hepatocellular carcinoma, R and D Systems HNF4A antibody (R&D Systems, PP-H1415) was used in immunohistochemistry - paraffin section on mouse samples. J Clin Invest (2015) ncbi
mouse monoclonal (H1415)
  • WB; mouse; 1:10000
R and D Systems HNF4A antibody (R&D Systems, PP-H1415-00) was used in western blot on mouse samples at 1:10000. Biochim Biophys Acta (2015) ncbi
mouse monoclonal (H1415)
  • IP; human
R and D Systems HNF4A antibody (R&D Systems, PP-H1415-00) was used in immunoprecipitation on human samples. Nucleic Acids Res (2014) ncbi
mouse monoclonal (H1415)
  • WB; human
R and D Systems HNF4A antibody (Perseus Proteomics, PP-H1415-00) was used in western blot on human samples. J Biol Chem (2015) ncbi
Abcam
mouse monoclonal (K9218)
  • IHC-P; human; 1:70
Abcam HNF4A antibody (Abcam, ab41898) was used in immunohistochemistry - paraffin section on human samples at 1:70. PLoS ONE (2014) ncbi
mouse monoclonal (K9218)
  • ChIP; mouse
Abcam HNF4A antibody (Abcam, ab41898) was used in chromatin immunoprecipitation on mouse samples. J Biol Chem (2013) ncbi
mouse monoclonal (K9218)
  • ChIP; human
  • ChIP; mouse
Abcam HNF4A antibody (Abcam, ab41898) was used in chromatin immunoprecipitation on human samples and on mouse samples. PLoS ONE (2013) ncbi
Invitrogen
mouse monoclonal (H1415)
  • IC; African green monkey; 1:25; fig 1
  • WB; African green monkey; 1:250; fig 1
In order to develop a cell culture system for fetal baboon hepatocytes and study phosphoenolpyruvate carboxykinase-1, Invitrogen HNF4A antibody (Invitrogen, 417700) was used in immunocytochemistry on African green monkey samples at 1:25 (fig 1) and in western blot on African green monkey samples at 1:250 (fig 1). J Med Primatol (2013) ncbi
Cell Signaling Technology
rabbit monoclonal (C11F12)
  • IC; rat
In order to study the effect of bile acids on mesenchymal stem cells in liver, Cell Signaling Technology HNF4A antibody (Cell Signaling, 3113S) was used in immunocytochemistry on rat samples. Sci Rep (2015) ncbi
rabbit monoclonal (C11F12)
  • IC; human; 1:100
In order to study two pluripotent stem cell populations in regards to a neural precurson cell population, Cell Signaling Technology HNF4A antibody (Cell Signaling Technologies, 3113S) was used in immunocytochemistry on human samples at 1:100. Stem Cell Res (2014) ncbi
rabbit monoclonal (C11F12)
  • WB; human
Cell Signaling Technology HNF4A antibody (Cell Signaling, 3113S) was used in western blot on human samples. J Virol (2014) ncbi
Articles Reviewed
  1. Xueru Mu et al. (2015). "Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment".PMID 26348897
  2. Xiao Ming Wang et al. (2015). "Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities".PMID 26319495
  3. Iris Sawitza et al. (2015). "Bile acids induce hepatic differentiation of mesenchymal stem cells".PMID 26304833
  4. Jing Liu et al. (2015). "Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism".PMID 26256888
  5. Ayaka Yanagida et al. (2015). "Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner".PMID 26165599
  6. Alexis Poncy et al. (2015). "Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts".PMID 26033091
  7. Carla Cicchini et al. (2015). "Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29".PMID 26003733
  8. Ayaka Yanagida et al. (2016). "Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells".PMID 25697415
  9. Luke Norton et al. (2014). "The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells".PMID 25414334
  10. Neal A Englert et al. (2015). "Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9".PMID 25391650
  11. Yuhong Zou et al. (2014). "Nrf2 is involved in maintaining hepatocyte identity during liver regeneration".PMID 25222179
  12. Thomas J Velenosi et al. (2014). "Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease".PMID 25208844
  13. Yohannes Hagos et al. (2014). "HNF4α induced chemosensitivity to oxaliplatin and 5-FU mediated by OCT1 and CNT3 in renal cell carcinoma".PMID 25175346
  14. Pasquale Simeone et al. (2014). "A unique four-hub protein cluster associates to glioblastoma progression".PMID 25050814
  15. Olga S Petrakova et al. (2014). "Comparative analysis reveals similarities between cultured submandibular salivary gland cells and liver progenitor cells".PMID 24790827
  16. I A Muchkaeva et al. (2014). "Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells".PMID 24772326
  17. Gail Doughton et al. (2014). "Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling".PMID 24752320
  18. Richard L Gieseck et al. (2014). "Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture".PMID 24466060
  19. Rafael Simo et al. (2014). "Thyroid hormone upregulates zinc-α2-glycoprotein production in the liver but not in adipose tissue".PMID 24465683
  20. Barbara S Mallon et al. (2014). "Comparison of the molecular profiles of human embryonic and induced pluripotent stem cells of isogenic origin".PMID 24374290
  21. Xinlei Li et al. (2014). "Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus".PMID 24173221
  22. Emrah Tümer et al. (2013). "Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks".PMID 24121511
  23. Huafang Ouyang et al. (2013). "Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription".PMID 23626788
  24. Cun Li et al. (2013). "Effects of maternal nutrient restriction, intrauterine growth restriction, and glucocorticoid exposure on phosphoenolpyruvate carboxykinase-1 expression in fetal baboon hepatocytes in vitro".PMID 23600855
  25. Siyeon Rhee et al. (2013). "Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development".PMID 23554936
  26. Zhongyan Wang et al. (2013). "The role of microRNAs in hepatocyte nuclear factor-4alpha expression and transactivation".PMID 23298640
  27. Niresh Hariparsad et al. (2009). "Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes".PMID 19129222
  28. Roong Zhao et al. (2008). "Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice".PMID 18400219
  29. Sung Hoon Ahn et al. (2008). "Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease".PMID 18338782
  30. Kwang Hoon Song et al. (2006). "A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene".PMID 16488887
  31. Tiangang Li et al. (2006). "Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression".PMID 16455805
  32. Vered Sheena et al. (2005). "Transcriptional regulation of human microsomal triglyceride transfer protein by hepatocyte nuclear factor-4alpha".PMID 15547294