This is a review about HLA-DRB1, based on 34 published articles (read how Labome selects the articles), using HLA-DRB1 antibody in all methods. It is aimed to help Labome visitors find the most suited HLA-DRB1 antibody.
HLA-DRB1 synonym: DRB1; DRw10; HLA-DR1B; HLA-DRB; SS1; DW2.2/DR2.2; HLA class II histocompatibility antigen, DR-1 beta chain; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class II antigen; human leucocyte antigen DRB1; lymphocyte antigen DRB1

BioLegend
mouse monoclonal (L243)
  • FC; human; fig 1
BioLegend HLA-DRB1 antibody (Biolegend, 307628) was used in flow cytometry on human samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in flow cytometry on human samples. Clin Cancer Res (2016) ncbi
mouse monoclonal (LN3)
  • FC; human; fig 1
In order to assess the CD4/CD8 ratio as a marker for CD4+ T cell dysfunction in chronic HIV infection, BioLegend HLA-DRB1 antibody (Biolegend, clone LN3) was used in flow cytometry on human samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (L243)
  • FC; human
In order to identify the cell surface markers in synovial mesenchymal stem cells, BioLegend HLA-DRB1 antibody (Biolegend, 307604) was used in flow cytometry on human samples. Cytometry A (2015) ncbi
mouse monoclonal (L243)
  • FC; human; fig 3
In order to investigate the dynamics and characteristics of natural killer cell types in the human ocular mucosal surface in situ during infection with group D human adenoviruses, BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples (fig 3). Mucosal Immunol (2016) ncbi
mouse monoclonal (Tü39)
  • FC; human
BioLegend HLA-DRB1 antibody (Biolegend, #361703) was used in flow cytometry on human samples. Am J Transplant (2015) ncbi
mouse monoclonal (L243)
  • FC; human; 1:1000
In order to compared leukocyte proportions and absolute counts using reference real-time methods with a novel assay that allows long-term cryopreservation of fixed leukocytes for later counting, BioLegend HLA-DRB1 antibody (BioLegend, 307626) was used in flow cytometry on human samples at 1:1000. Cytometry A (2015) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. J Infect Dis (2015) ncbi
mouse monoclonal (L243)
  • FC; human
In order to discuss how inflammation contributes to pulmonary arterial hypertension, BioLegend HLA-DRB1 antibody (BioLegend, clone L243) was used in flow cytometry on human samples. Chest (2015) ncbi
mouse monoclonal (L243)
  • IHC-P; human
BioLegend HLA-DRB1 antibody (BioLegend, clone L243) was used in immunohistochemistry - paraffin section on human samples. Exp Dermatol (2014) ncbi
mouse monoclonal (L243)
  • FC; human
In order to identify the role of GammaDelta T cells in acute HIV infection, BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. PLoS ONE (2014) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in flow cytometry on human samples. J Leukoc Biol (2014) ncbi
mouse monoclonal (L243)
  • FC; human
In order to examine the effect of lytic EBV antigen-specific CD8+ T cells on EBV infection in humanized mice, BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. PLoS Pathog (2014) ncbi
mouse monoclonal (L243)
  • FC; Rhesus monkey
In order to examine the diagnostic value of mannose receptor CD206 in HIV and simian immunodeficiency virus encephalitis, BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in flow cytometry on Rhesus monkey samples. J Neuroimmune Pharmacol (2014) ncbi
mouse monoclonal (L243)
  • FC; human; fig 1
In order to study the role of plasmacytoid dendritic cells in human immunodeficiency virus type 1 infection and pathogenesis, BioLegend HLA-DRB1 antibody (Biolegend, 307604) was used in flow cytometry on human samples (fig 1). PLoS Pathog (2014) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in flow cytometry on human samples. Clin Cancer Res (2014) ncbi
mouse monoclonal (L243)
  • WB; human
BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in western blot on human samples. Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (BioLegend, L243) was used in flow cytometry on human samples. J Immunol (2014) ncbi
mouse monoclonal (L243)
  • FC; human
In order to determine the presence, frequency, association to other immune parameters, and functional properties of circulating CD14(+) cells lacking HLA-DR expression in patients with untreated chronic lymphocytic leukemia, BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. Blood (2014) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. Front Immunol (2014) ncbi
mouse monoclonal (L243)
  • FC; human
BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. Front Immunol (2014) ncbi
mouse monoclonal (L243)
  • FC; human
In order to investigate the progression of innate responses to mycobacteria in infants, BioLegend HLA-DRB1 antibody (Biolegend, L243) was used in flow cytometry on human samples. J Immunol (2014) ncbi
not indicated
  • FC; human
Biolegend anti-HLADR was used in 2ug/ml to perform mass cytometry in order to show that different stimulation effect of human hematopoietic cells could be analysized by single-cell mass cytometry.Science (2011) ncbi
Invitrogen
mouse monoclonal (CR3/43)
  • IHC; human; tbl 1
In order to study the recognition of tumor mutations by T-cells during the transition from primary to recurrent ovarian cancer, Invitrogen HLA-DRB1 antibody (Affinity Bioreagents, MAI-25914) was used in immunohistochemistry on human samples (tbl 1). Clin Cancer Res (2014) ncbi
mouse monoclonal (LN-3)
  • IHC-P; Rhesus monkey; 1:200; tbl 2
  • FC; Rhesus monkey; fig 7
In order to study the host inflammatory granulomatous response that controls cutaneous leishmaniasis using a macaque model, Invitrogen HLA-DRB1 antibody (Zymed Laboratory, clone LN-3) was used in immunohistochemistry - paraffin section on Rhesus monkey samples at 1:200 (tbl 2) and in flow cytometry on Rhesus monkey samples (fig 7). J Pathol (2008) ncbi
mouse monoclonal (LN-3)
  • IHC-F; human; fig 6
  • FC; human; fig 4
In order to determine the expression of a human macrophage lectin specific for galactose/N-acetylgalactosamine during macrophage differentiation, Invitrogen HLA-DRB1 antibody (Zymed, LN-3) was used in immunohistochemistry - frozen section on human samples (fig 6) and in flow cytometry on human samples (fig 4). Int Immunol (2002) ncbi
mouse monoclonal (HL-38)
  • FC; human; 4 ug/ml
In order to characterize human splenic dendritic cells, Invitrogen HLA-DRB1 antibody (Caltag, HL38) was used in flow cytometry on human samples at 4 ug/ml. Blood (2001) ncbi
mouse monoclonal (HL-38)
  • FC; human; fig 3
In order to test if recombinant human interferon-gamma enhancing clearance of microbes in patients with chronic granulomatous disease, Invitrogen HLA-DRB1 antibody (Caltag, HL38) was used in flow cytometry on human samples (fig 3). Blood (1997) ncbi
mouse monoclonal (HL-38)
  • FC; human
In order to describe the cellular changes that IFN beta-1b treatment induced in the experimental autoimmune encephalomyelitis model, Invitrogen HLA-DRB1 antibody (Caltag, HL38) was used in flow cytometry on human samples. J Clin Invest (1997) ncbi
Santa Cruz Biotechnology
mouse monoclonal (TAL 14.1)
  • IP; mouse
In order to assess the impact of the different HLA-DR15 haplotype alleles on disease susceptibility in a new humanized multiple sclerosis model, Santa Cruz Biotechnology HLA-DRB1 antibody (Santa Cruz Biotechnology, TAL 14.1) was used in immunoprecipitation on mouse samples. J Biol Chem (2015) ncbi
Abcam
not indicated
  • WB; human
  • IHC; human
  • IC; human
  • FC; human
Abcam anti-HLA-DRB (ab20183) antibody was used to perform western blot, flow cytometry, and immunohistochemistry/immunocytochemistry in order to study the altered expression levels of metastasis-related plasma membrane proteins of human breast cancer cells.Mol Cell Proteomics (2009) ncbi
BD Biosciences
not indicated
  • FC; human
Becton Dickinson anti-HLA-DR-PE-Cy7 antibody was used to perform flow cytometry in order to study the role of the EPEC protein NleE in inhibiting NF-kappa B signaling in human dendritic cells.J Immunol (2010) ncbi
not indicated
  • FC; human
BD Biosciences anti-HLA antibody was used to perform flow cytometric analysis in order to study the determinants ofthe level of viremia in naturally SIV-infected SMs.J Clin Invest (2008) ncbi
not indicated
  • FC; human
BD Biosciences anti-HLA class II monoclonal antibody was used to perform flow cytometry in order to study the role of human BM-derived MSCs expressed TLR3 and TLR4 in inhibiting their T-Cell modulatory activity.Stem Cells (2008) ncbi
Articles Reviewed
  1. Marie R McCausland et al. (2015). "Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy".PMID 26430882
  2. Maximillian Rosario et al. (2016). "The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas".PMID 26423796
  3. Juliet Frederiksen et al. (2015). "Multidimensional Clusters of CD4+ T Cell Dysfunction Are Primarily Associated with the CD4/CD8 Ratio in Chronic HIV Infection".PMID 26402620
  4. Jaroslav Denkovskij et al. (2015). "Cell surface markers and exogenously induced PpIX in synovial mesenchymal stem cells".PMID 26355501
  5. N Yawata et al. (2016). "Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection".PMID 26080707
  6. Nathali Kaushansky et al. (2015). "Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease".PMID 25911099
  7. K A Thomas et al. (2015). "An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA".PMID 25904443
  8. Elisa Nemes et al. (2015). "Differential leukocyte counting and immunophenotyping in cryopreserved ex vivo whole blood".PMID 25515205
  9. Kateena Addae Konadu et al. (2015). "Association of Cytokines With Exosomes in the Plasma of HIV-1-Seropositive Individuals".PMID 25512626
  10. Aur lie Hautefort et al. (2015). "T-helper 17 cell polarization in pulmonary arterial hypertension".PMID 25429518
  11. Patrizia Stoitzner et al. (2014). "Human skin dendritic cells can be targeted in situ by intradermal injection of antibodies against lectin receptors".PMID 25346475
  12. Zhen Li et al. (2014). "γδ T cells are involved in acute HIV infection and associated with AIDS progression".PMID 25188438
  13. Yinxia Chao et al. (2014). "Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα".PMID 25170117
  14. Olga Antsiferova et al. (2014). "Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice".PMID 25165855
  15. Gerard E Holder et al. (2014). "Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection".PMID 25146376
  16. Guangming Li et al. (2014). "Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice".PMID 25077616
  17. Shigeo Koido et al. (2014). "Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer".PMID 25056373
  18. Janna Schneppenheim et al. (2014). "Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells".PMID 25035924
  19. Norihito Kawasaki et al. (2014). "Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation".PMID 25000981
  20. Regina Jitschin et al. (2014). "CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs".PMID 24850760
  21. Maria E Moreno-Fernandez et al. (2014). "Regulatory T Cells Diminish HIV Infection in Dendritic Cells - Conventional CD4(+) T Cell Clusters".PMID 24847325
  22. Matthew W Klinker et al. (2014). "Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes".PMID 24765093
  23. Muki S Shey et al. (2014). "Maturation of innate responses to mycobacteria over the first nine months of life".PMID 24733845
  24. Darin A Wick et al. (2014). "Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer".PMID 24323902
  25. Sean C Bendall et al. (2011). "Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum".PMID 21551058
  26. Anna Vossenkamper et al. (2010). "Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE".PMID 20833837
  27. Rikke Leth-Larsen et al. (2009). "Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry".PMID 19321434
  28. C Souza-Lemos et al. (2008). "Dynamics of immune granuloma formation in a Leishmania braziliensis-induced self-limiting cutaneous infection in the primate Macaca mulatta".PMID 18702174
  29. Nichole R Klatt et al. (2008). "Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys".PMID 18497876
  30. Francesco Liotta et al. (2008). "Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling".PMID 17962701
  31. Nobuaki Higashi et al. (2002). "Human macrophage lectin specific for galactose/N-acetylgalactosamine is a marker for cells at an intermediate stage in their differentiation from monocytes into macrophages".PMID 12039906
  32. D McIlroy et al. (2001). "Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors".PMID 11369639
  33. D E Schiff et al. (1997). "Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects".PMID 9376602
  34. K Genc et al. (1997). "Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy".PMID 9169496