This is a review about GSK3, based on 19 published articles (read how Labome selects the articles), using GSK3 antibody in all methods. It is aimed to help Labome visitors find the most suited GSK3 antibody.
GSK3 synonym: GSK-3 alpha; glycogen synthase kinase-3 alpha; serine/threonine-protein kinase GSK3A

EMD MilliporeEMD Millipore GSK3 product
  • western blotIn 2009, Michel Varrin-Doyer et al. applied EMD Millipore GSK3 antibody to perform western blot in order to investigate the molecular mechanisms underlying CRMP2 function in CXCL12-induced T lymphocyte migration [ncbi , more ]. In 2002, Russell D Klein et al. used EMD Millipore GSK3 antibody to study the effects of black tea polyphenols on IGF-I signal transduction pathways in normal prostate epithelial cells and Du145 prostate carcinoma cells [ncbi , more ].
Cell Signaling TechnologyCell Signaling Technology GSK3 product
  • immunoprecipitationIn 2002, Marianne O Price et al. used Cell Signaling Technology GSK3 antibody to study the role of Rac NADPH oxidase activation [ncbi , more ].
  • western blotIn 2010, Saurabh Sahar et al. employed Cell Signaling Technology GSK3 antibody to investigate the role of CDC5 in the regulation of the checkpoint kinase Rad53 hyperphosphorylation [ncbi , more ]. In 2009, Byoung Kwon Yoo et al. utilized Cell Signaling Technology GSK3 antibody to carry out western blot analysis in order to investigate the role for AEG1 in regulating Hepatocellular carcinoma pathogenesis [ncbi , more ]. Mei Hua Gao et al. utilized Cell Signaling Technology GSK3 antibody to perform immunoblot in order to study the Akt activity and phospholamban phosphorylation increased by adenylyl cyclase type VI [ncbi , more ] in 2008 and Min Huei Liang et al. used Cell Signaling Technology GSK3 antibody to demonstrate that lithium suppresses Smad3/4-dependent TGF-beta-responsive gene transactivation [ncbi , more ]. In 2007, James G Greger et al. applied Cell Signaling Technology GSK3 antibody to study the role of MNAR in 17beta-estradiol (E2) induced activation of the phosphatidylinositol 3-kinase (PI3K) /Akt pathway [ncbi , more ]. Cell Signaling Technology GSK3 antibody was employed in 2005 to study transcriptional stimulation in colon cancer by prostaglandin E2 [ncbi , more ], to evaluate the role of NF-kappa B- and C/EBP beta-driven interleukin-1 beta gene expression and PAK1-mediated caspase-1 activation in interleukin-1 beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages [ncbi , more ]and to study whether SCH66336 inhibits angiogenesis of aerodigestive tract cancer cells [ncbi , more ]. Holger Buss et al. employed Cell Signaling Technology GSK3 antibody to detect phospho-GSK-3alpha in HeLa cells treated with or without calyculin A [ncbi , more ] in 2004 and Saveria Aquila et al. used Cell Signaling Technology GSK3 antibody to detect phospho-GSK-3 in human ejaculate spermatozoa [ncbi , more ]. Kohjiro Ueki et al. used Cell Signaling Technology GSK3 antibody to demonstrate that p85 alpha and p85 beta modulate PI 3-kinase-dependent signaling by multiple mechanisms and transmit signals independent of PI 3-kinase activation [ncbi , more ] in 2003 and Yu Li et al. used Cell Signaling Technology GSK3 antibody to detect phospho-gsk3 in CHO cell expressing the IR and IRS-1 transfected with MOR [ncbi , more ]. Cell Signaling Technology GSK3 antibody was used in 2002 to study the effect of VIIa/tissue factor interaction [ncbi , more ], to study cell survival by GLP-2R signaling [ncbi , more ], to study the role of Rac NADPH oxidase activation [ncbi , more ]and to study the mechanism by which IGF-I induces the activation of the cyclin D1-CDK4 complex [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology GSK3 product
  • western blotIn 2012, Shu Yong Lin et al. utilized Santa Cruz Biotechnology GSK3 antibody to perform western blot in order to investigate the role of GSK3-TIP60-ULK1 signaling pathway in autophagy [ncbi , more ]. In 2008, Min Huei Liang et al. used Santa Cruz Biotechnology GSK3 antibody to demonstrate that lithium suppresses Smad3/4-dependent TGF-beta-responsive gene transactivation [ncbi , more ]. In 2002, Henri H Versteeg et al. utilized Santa Cruz Biotechnology GSK3 antibody to study the effect of VIIa/tissue factor interaction [ncbi , more ].
BD Biosciences
  • western blotIn 2010, Saurabh Sahar et al. employed BD Biosciences GSK3 antibody to investigate the role of CDC5 in the regulation of the checkpoint kinase Rad53 hyperphosphorylation [ncbi , more ].
Articles Reviewed
  1. Shu Yong Lin et al. (2012). "GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy".PMID 22539723
  2. Saurabh Sahar et al. (2010). "Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation".PMID 20049328
  3. Michel Varrin-Doyer et al. (2009). "Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration".PMID 19276087
  4. Byoung Kwon Yoo et al. (2009). "Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression".PMID 19221438
  5. Mei Hua Gao et al. (2008). "Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes".PMID 18838385
  6. Min Huei Liang et al. (2008). "Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling".PMID 18077182
  7. James G Greger et al. (2007). "Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase".PMID 17194752
  8. Ji-Youn Han et al. (2005). "Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer".PMID 16145048
  9. Jinyi Shao et al. (2005). "Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer".PMID 15899904
  10. Chaitali Basak et al. (2005). "NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages".PMID 15561713
  11. Holger Buss et al. (2004). "Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity".PMID 15465828
  12. Saveria Aquila et al. (2004). "Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway".PMID 15001646
  13. Kohjiro Ueki et al. (2003). "Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling".PMID 14504291
  14. Yu Li et al. (2003). "Morphine induces desensitization of insulin receptor signaling".PMID 12917346
  15. Irene H L Hamelers et al. (2002). "Insulin-like growth factor I triggers nuclear accumulation of cyclin D1 in MCF-7S breast cancer cells".PMID 12364325
  16. Henri H Versteeg et al. (2002). "VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation".PMID 12019261
  17. Bernardo Yusta et al. (2002). "Glucagon-like peptide-2 receptor activation engages bad and glycogen synthase kinase-3 in a protein kinase A-dependent manner and prevents apoptosis following inhibition of phosphatidylinositol 3-kinase".PMID 11978789
  18. Marianne O Price et al. (2002). "Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent".PMID 11896053
  19. Russell D Klein et al. (2002). "Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells".PMID 11756245