This is a review about Flt-1, based on 16 published articles (read how Labome selects the articles), using Flt-1 antibody in all methods. It is aimed to help Labome visitors find the most suited Flt-1 antibody.
Flt-1 synonym: FLT; FLT-1; VEGFR-1; VEGFR1; fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; vascular permeability factor receptor

R and D SystemsR and D Systems Flt-1 product
  • immunohistochemistryIn 2008, Kaili Mao et al. applied R and D Systems Flt-1 antibody to perform immunochemistry assays in order to demonstrate that VEGFR-1 expression is not related to the risk of cancer progression following radical prostatectomy (catalog: AF321) [ncbi , more ].
  • western blotIn 2003, Ida Casella et al. used R and D Systems Flt-1 antibody to provide evidence that autocrine-paracrine VEGF loops may functionally operate in the maturation of megakaryocytic precursors through Flt1 receptor [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology Flt-1 product
  • immunohistochemistryChristina Magkou et al. used Santa Cruz Biotechnology Flt-1 antibody to investigate the expressions of EGFR and pEGFR and their correlation with overall and disease-free survival, clinicopathological parameters and biological markers of invasion and angiogenesis [ncbi , more ] in 2008 and Akihiro Kakehashi et al. used Santa Cruz Biotechnology Flt-1 antibody to perform immunohistochemistry in order to study the functions and relations of vascular endothelial growth factor (VEGF), advanced glycation end products (AGEs), VEGF receptor (flt-1), and macrophages in the progress of proliferative diabetic retinopathy [ncbi , more ]. In 2007, Alice P Taylor et al. used Santa Cruz Biotechnology Flt-1 antibody to study the role of placenta growth factor in malignancy [ncbi , more ]. In 2003, J Sato et al. employed Santa Cruz Biotechnology Flt-1 antibody to study its expression in synovial tissues [ncbi , more ]. Hua Zhang et al. used Santa Cruz Biotechnology Flt-1 antibody to detect the expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt-1 in gastric carcinoma cell lines [ncbi , more ] in 2002 and Kumi Yasukawa et al. used Santa Cruz Biotechnology Flt-1 antibody to provide evidence that there is systemic production of VEGF and flt-1 in acute Kawasaki disease [ncbi , more ]. In 2001, B Moller et al. applied Santa Cruz Biotechnology Flt-1 antibody to detect VEGFR-1 in biopsies from both the anterior and posterior walls of the patients uterus (catalog: sc-316) [ncbi , more ].
  • immunoprecipitationIn 2006, Rosana D Meyer et al. applied Santa Cruz Biotechnology Flt-1 antibody to detect FLT-1 in serum-starved PAE cells expressing FLT-1 and VEGFR-2 [ncbi , more ]. In 2005, Sophia Ran et al. utilized Santa Cruz Biotechnology Flt-1 antibody to isolate FLT-1 from human breast cancer cell lines BT474, MDA-MB-231, MDA-MB-435, and SK-BR3, and in western blot to detect FLT-1 expression in human breast carcinoma MDA-MB-231 cells [ncbi , more ].
  • western blotIn 2007, Alice P Taylor et al. used Santa Cruz Biotechnology Flt-1 antibody to study the role of placenta growth factor in malignancy [ncbi , more ]. In 2006, Rosana D Meyer et al. applied Santa Cruz Biotechnology Flt-1 antibody to detect FLT-1 in serum-starved PAE cells expressing FLT-1 and VEGFR-2 [ncbi , more ]. Santa Cruz Biotechnology Flt-1 antibody was applied in 2005 to investigate the regulatoin of VEGFR2/KDR by KLF2 [ncbi , more ], to isolate FLT-1 from human breast cancer cell lines BT474, MDA-MB-231, MDA-MB-435, and SK-BR3, and in western blot to detect FLT-1 expression in human breast carcinoma MDA-MB-231 cells [ncbi , more ]and to study the role for dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling in human umbilical vein endothelial cells (HUVECs) [ncbi , more ]. In 2003, Tomowaki Nakagawa et al. employed Santa Cruz Biotechnology Flt-1 antibody to study the negative regulation of angiogenesis by HEX [ncbi , more ]. In 2001, B Moller et al. applied Santa Cruz Biotechnology Flt-1 antibody to detect VEGFR-1 in biopsies from both the anterior and posterior walls of the patients uterus (catalog: sc-316) [ncbi , more ].
EMD MilliporeEMD Millipore Flt-1 product
  • immunocytochemistryIn 2002, Maria Chiara Deregibus et al. utilized EMD Millipore Flt-1 antibody to study the molecular mechanisms through which HIV-1-Tat protein inhibits vincristine-induced apoptosis of KS cells [ncbi , more ].
WILEX Inc.
  • immunohistochemistryIn 2008, Toshio Kuwai et al. used WILEX Inc. Flt-1 antibody to study whether the expression of tyrosine kinase growth factor receptors is constant or varies between and within individual colon cancer neoplasms [ncbi , more ].
Articles Reviewed
  1. Christina Magkou et al. (2008). "Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas".PMID 18522728
  2. Toshio Kuwai et al. (2008). "Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors".PMID 18202197
  3. Kaili Mao et al. (2008). "The association of vascular endothelial growth factor receptor-1 with the risk of cancer progression following radical prostatectomy".PMID 18097592
  4. Akihiro Kakehashi et al. (2008). "Relationship among VEGF, VEGF receptor, AGEs, and macrophages in proliferative diabetic retinopathy".PMID 18053608
  5. Alice P Taylor et al. (2007). "Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts".PMID 17308051
  6. Rosana D Meyer et al. (2006). "A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1".PMID 16286478
  7. Resham Bhattacharya et al. (2005). "Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling".PMID 16049137
  8. Resham Bhattacharya et al. (2005). "Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2".PMID 15980434
  9. Sophia Ran et al. (2005). "The vascular-ablative agent VEGF(121)/rGel inhibits pulmonary metastases of MDA-MB-231 breast tumors".PMID 15967101
  10. J Sato et al. (2003). "Correlations of the expression of fibroblast growth factor-2, vascular endothelial growth factor, and their receptors with angiogenesis in synovial tissues from patients with internal derangement of the temporomandibular joint".PMID 12651930
  11. Tomowaki Nakagawa et al. (2003). "HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro".PMID 12588764
  12. Hua Zhang et al. (2002). "Expression of vascular endothelial growth factor and its receptors KDR and Flt-1 in gastric cancer cells".PMID 12439912
  13. Ida Casella et al. (2003). "Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor".PMID 12406876
  14. Maria Chiara Deregibus et al. (2002). "HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells".PMID 11994280
  15. Kumi Yasukawa et al. (2002). "Systemic production of vascular endothelial growth factor and fms-like tyrosine kinase-1 receptor in acute Kawasaki disease".PMID 11839635
  16. B Moller et al. (2001). "Expression of the angiogenic growth factors VEGF, FGF-2, EGF and their receptors in normal human endometrium during the menstrual cycle".PMID 11134362