This is a review about FANCD2, based on 20 published articles (read how Labome selects the articles), using FANCD2 antibody in all methods. It is aimed to help Labome visitors find the most suited FANCD2 antibody.
FANCD2 synonym: FA-D2; FA4; FACD; FAD; FAD2; FANCD; Fanconi anemia, complementation group D2

Abcam
rabbit polyclonal
  • WB (knockdown); human; fig 1
Abcam FANCD2 antibody (Abcam, ab2187) was used in western blot (knockdown) on human samples (fig 1). Oncoscience (2014) ncbi
rabbit monoclonal (EPR2302)
  • WB; human; 1:1000
Abcam FANCD2 antibody (Abcam, EPR2302) was used in western blot on human samples at 1:1000. DNA Repair (Amst) (2014) ncbi
rabbit polyclonal
  • WB; human
Abcam FANCD2 antibody (Abcam, ab2187) was used in western blot on human samples. Cell Rep (2014) ncbi
rabbit polyclonal
  • WB; human
Abcam FANCD2 antibody (Abcam, ab2187) was used in western blot on human samples. Nucleic Acids Res (2014) ncbi
rabbit polyclonal
  • IC; human; 1:4000
Abcam FANCD2 antibody (Abcam, ab2187) was used in immunocytochemistry on human samples at 1:4000. Hum Mol Genet (2014) ncbi
rabbit polyclonal
  • IC; human; fig 4
Abcam FANCD2 antibody (Abcam, ab2187) was used in immunocytochemistry on human samples (fig 4). Cell (2014) ncbi
rabbit polyclonal
  • IC; mouse
  • WB; mouse
Abcam FANCD2 antibody (Abcam, ab2187) was used in immunocytochemistry on mouse samples and in western blot on mouse samples. Nucleic Acids Res (2013) ncbi
rabbit monoclonal (EPR2302)
  • IC; mouse
  • WB; mouse
Abcam FANCD2 antibody (Abcam, ab108928) was used in immunocytochemistry on mouse samples and in western blot on mouse samples. Nucleic Acids Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (FI17)
  • WB; human; 1:500; fig 2
Santa Cruz Biotechnology FANCD2 antibody (Santa Cruz, sc-20022) was used in western blot on human samples at 1:500 (fig 2). Cancer Res (2015) ncbi
mouse monoclonal (FI17)
  • WB; human; 1:1000; fig 2, 3
Santa Cruz Biotechnology FANCD2 antibody (Santa Cruz, sc-20022) was used in western blot on human samples at 1:1000 (fig 2, 3). Cell Cycle (2015) ncbi
mouse monoclonal (FI17)
  • WB; human; 1:500; fig 5
Santa Cruz Biotechnology FANCD2 antibody (Santa Cruz Biotechnologies, sc-20022) was used in western blot on human samples at 1:500 (fig 5). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (FI17)
  • WB; human
Santa Cruz Biotechnology FANCD2 antibody (Santa, SC-20022) was used in western blot on human samples. Cell Rep (2014) ncbi
mouse monoclonal (FI17)
  • WB; human; 1:750; fig s5
  • IC; human; 1:400
Santa Cruz Biotechnology FANCD2 antibody (Santa, sc-20022) was used in western blot on human samples at 1:750 (fig s5) and in immunocytochemistry on human samples at 1:400. Nat Chem Biol (2014) ncbi
mouse monoclonal (FI17)
  • WB; human
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, Santa Cruz Biotechnology FANCD2 antibody (Santa Cruz, sc20022) was used in western blot on human samples. Nat Genet (2011) ncbi
not indicated
  • WB; human
  • IC; human
Santa Cruz Biotechnology anti-FANCD2 monoclonal antibody was used to carry out western blot analysis and immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex.Science (2010) ncbi
not indicated
  • WB; human
  • IC; human
Santa Cruz monoclonal mouse anti-human FANCD2 antibody was used in western blot to assess the efficiency of siRNA-mediated depletion of FANCD2 protein in human colorectal adenocarcinoma RKO cells and in immunocytochemistry to detect FANCD2 nuclear focus formation in human DLD1 colorectal adenocarcinoma cells.Cancer Biol Ther (2007) ncbi
not indicated
  • IP; human
Santa Cruz Biotechnology goat anti-FANCD2 antibody was used in immunoprecipitation to study the ternary complex of FANCC, FANCE, and FANCD2J Biol Chem (2005) ncbi
not indicated
  • WB; human
  • IC; human
Santa Cruz Biotechnology anti-FANCD2 antibody was used in western blot and immunocytochemistry to study to DNA damage responseJ Biol Chem (2005) ncbi
Novus Biologicals
rabbit polyclonal
  • IC; human; 1:200; fig 2
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples at 1:200 (fig 2). Cancer Res (2015) ncbi
rabbit polyclonal
  • IC; human; 1:200; fig 5
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples at 1:200 (fig 5). DNA Repair (Amst) (2015) ncbi
rabbit polyclonal
  • WB; human
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in western blot on human samples. Cell Rep (2014) ncbi
rabbit polyclonal
  • WB; human
  • IC; human
In order to study the role of an amino terminal FANCD2 nuclear localization signal in the coordinated nuclear localization of both FANCD2 and FANCI, Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples and in immunocytochemistry on human samples. PLoS ONE (2013) ncbi
rabbit polyclonal
  • IC; human; 1:200
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in immunocytochemistry on human samples at 1:200. Nat Genet (2011) ncbi
not indicated
  • IC; human
Novus Biological anti-FANCD2 polyclonal antibody was used to carry out immunofluorescence assays in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex.Science (2010) ncbi
Epitomics
rabbit monoclonal
  • WB; mouse
Epitomics FANCD2 antibody (Epitomics, 2986-1) was used in western blot on mouse samples. Nucleic Acids Res (2013) ncbi
LifeSpan Biosciences
rabbit polyclonal
  • WB; chicken
  • WB; human
LifeSpan Biosciences FANCD2 antibody (LS Bio, LS-B493) was used in western blot on chicken samples and on human samples. PLoS ONE (2013) ncbi
GeneTex
rabbit polyclonal
  • IC; Rhesus monkey; fig 6
GeneTex FANCD2 antibody (Genetex, GTX30142) was used in immunocytochemistry on Rhesus monkey samples (fig 6). J Virol (2010) ncbi
not indicated
  • IC; human
Genetex FANCD2 was used in immunocytochemistry in order to study the role for FA pathways in the maintenance of differentiation-dependent cell cycle exitOncogene (2009) ncbi
GE Healthcare Life Biosciences
not indicatedDharmacon Research FANCD2 siRNA duplexes were used to silence the expression of FANCD2 in order to investigate the role for FAN1 in promoting DNA interstrand cross-link repair by mono-ubiquitylating FANCI-FANCD2 complex.Science (2010) ncbi
Sigma-Aldrich
not indicated
  • IC; human
Sigma-Aldrich anti-FANCD2 antibody was used in immunocytochemistry in order to study the role for FA pathways in the maintenance of differentiation-dependent cell cycle exitOncogene (2009) ncbi
Articles Reviewed
  1. Chantal Stoepker et al. (2015). "Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer".PMID 26122845
  2. Maya Raghunandan et al. (2015). "FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex".PMID 25659033
  3. Chantal Stoepker et al. (2015). "DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity".PMID 25583207
  4. Keffy R M Kehrli et al. (2014). "Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells".PMID 25580447
  5. Luisa Schmidt et al. (2014). "ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress".PMID 25262557
  6. Yaling Huang et al. (2014). "Modularized functions of the Fanconi anemia core complex".PMID 24910428
  7. Meilen C Munoz et al. (2014). "An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells".PMID 24829461
  8. Jung Eun Yeo et al. (2014). "CtIP mediates replication fork recovery in a FANCD2-regulated manner".PMID 24556218
  9. Qin Liang et al. (2014). "A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses".PMID 24531842
  10. Nadine Laguette et al. (2014). "Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing".PMID 24412650
  11. Rebecca A Boisvert et al. (2013). "Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal".PMID 24278431
  12. Spencer W Luebben et al. (2013). "Helq acts in parallel to Fancc to suppress replication-associated genome instability".PMID 24005041
  13. Munkhbold Tuul et al. (2013). "Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance".PMID 23383325
  14. Chantal Stoepker et al. (2011). "SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype".PMID 21240277
  15. Ting Liu et al. (2010). "FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair".PMID 20671156
  16. Sergei Boichuk et al. (2010). "Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen".PMID 20519379
  17. E E Hoskins et al. (2009). "Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture".PMID 19015634
  18. Eike Gallmeier et al. (2007). "Gene-specific selection against experimental fanconi anemia gene inactivation in human cancer".PMID 17387268
  19. Susan M Gordon et al. (2005). "FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway".PMID 16127171
  20. Akihiro Ohashi et al. (2005). "Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage".PMID 15671039