This is a review about F2, based on 6 published articles (read how Labome selects the articles), using F2 antibody in all methods. It is aimed to help Labome visitors find the most suited F2 antibody.
F2 synonym: RPRGL2; THPH1; coagulation factor II (thrombin); prepro-coagulation factor II; prothrombin B-chain; serine protease

Santa Cruz Biotechnology
goat polyclonal (K-20)
  • IHC; human; 1:50
Santa Cruz Biotechnology F2 antibody (Santa Cruz Biotechnology, Sc-16972) was used in immunohistochemistry on human samples at 1:50. Am J Pathol (2010) ncbi
Invitrogen
not indicatedThermo Fisher Scientific biotinylated thrombin was used to perform protein purification to evaluate a novel screening method for the discovery of next-generation drugs against Plasmodium liver stages.Science (2011) ncbi
Roche Applied Science
not indicatedRoche thrombin was used to activate samples in order to study the effects of the lack of CD63 on renal function and lysosomal function.Mol Cell Biol (2009) ncbi
Sigma-Aldrich
not indicatedSigma-Aldrich thrombin was used to induce the anaphylactic reactions in order to investigate the role of endothelial Gq/G11-mediated signaling in regulating anaphylactic reactions.J Exp Med (2009) ncbi
not indicatedSigma human thrombin was used to prepare fibrin standards in order to develop a mouse model of HUS by administering endotoxin-free Stx2 and study the role of anti-Stx2 antibody in protection from lethal outcome.Infect Immun (2008) ncbi
Enzyme Research Laboratories
not indicatedEnzyme Research Laboratories human alpha-thrombin was used to perform fibrin clots formation in order to show that obstructed blood vessels could be targeted by shear-activated nanotherapeutics.Science (2012) ncbi
Articles Reviewed
  1. Netanel Korin et al. (2012). "Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels".PMID 22767894
  2. Stephan Meister et al. (2011). "Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery".PMID 22096101
  3. Xiangling Yin et al. (2010). "Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease".PMID 20150433
  4. Hanna Korhonen et al. (2009). "Anaphylactic shock depends on endothelial Gq/G11".PMID 19171764
  5. Jenny Schröder et al. (2009). "Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function".PMID 19075008
  6. Kristin A D Sauter et al. (2008). "Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody".PMID 18694970