This is a review about Egr-1, based on 35 published articles (read how Labome selects the articles), using Egr-1 antibody in all methods. It is aimed to help Labome visitors find the most suited Egr-1 antibody.
Egr-1 synonym: AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225; EGR-1; nerve growth factor-induced protein A; transcription factor ETR103; transcription factor Zif268; zinc finger protein 225; zinc finger protein Krox-24

Santa Cruz Biotechnology
rabbit polyclonal (588)
  • WB; human
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-110) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal (588)
  • ChIP; mouse; fig 5
  • WB; human; fig 10
  • WB; mouse; fig 1
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-110) was used in chromatin immunoprecipitation on mouse samples (fig 5) and in western blot on human samples (fig 10) and on mouse samples (fig 1). Mol Cell Biol (2015) ncbi
rabbit polyclonal (C-19)
  • IHC; mouse; 1:5000; fig 3
In order to investigate how PSD-95 contributes to fear memory formation and retrieval, Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-189) was used in immunohistochemistry on mouse samples at 1:5000 (fig 3). Mol Psychiatry (2015) ncbi
rabbit polyclonal (588)
  • WB; human; 1:1000
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-110) was used in western blot on human samples at 1:1000. Biochem Pharmacol (2014) ncbi
rabbit polyclonal (C-19)
  • IHC-Free; prairie vole; 1:8000
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-189) was used in immunohistochemistry - free floating section on prairie vole samples at 1:8000. Neuropharmacology (2014) ncbi
mouse monoclonal (S-25)
  • IHC; human; 1:500
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, SC-101033) was used in immunohistochemistry on human samples at 1:500. Neuropsychopharmacology (2014) ncbi
rabbit polyclonal (C-19)
  • EMSA; mouse
  • EMSA; rat
In order to study the upregulation of pancreatic beta cell ARAP1 by a functional regulatory DNA variant at a type 2 diabetes locus, Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-189X) was used in EMSA on mouse samples and on rat samples. Am J Hum Genet (2014) ncbi
rabbit polyclonal (C-19)
  • IHC; rat; 1:2,000, 1:2,500
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz, sc-189) was used in immunohistochemistry on rat samples at 1:2,000, 1:2,500. Brain Struct Funct (2014) ncbi
rabbit polyclonal (588)
  • WB; mouse; 1:400
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-110) was used in western blot on mouse samples at 1:400. Mol Endocrinol (2013) ncbi
rabbit polyclonal (588)
  • WB; human
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-110) was used in western blot on human samples. Stem Cells (2012) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology rabbit anti-human Egr-1 antibody was used to perform immunoblotting in order to study the important role of ERK1/2 in mediating IL-13-induced monocyte 15-LO expression.J Immunol (2010) ncbi
rabbit polyclonal (C-19)
  • IHC-F; zebra finch; 1:1,000
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-189) was used in immunohistochemistry - frozen section on zebra finch samples at 1:1,000. J Comp Neurol (2009) ncbi
rabbit polyclonal (588)
  • WB; human
Santa Cruz anti-EGR1 rabbit antibody (1:1000) was used to perform western blot in order to study how to modulate gene expression and develop new drugs by short chain fatty acid (SCFA) hexosamine molecules.J Med Chem (2009) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-Egr1 antibody (1:500) was used to perform western blot in order to study the mechanism of posttranscriptional regulation of interleukin-10 by miR-106a.Proc Natl Acad Sci U S A (2009) ncbi
rabbit polyclonal (588)
  • IHC; human
Santa Cruz Biotechnology polyclonal rabbit anti-Egr-1 antibody was used in immunohistochemistry in order to investigate the role of Arc in the regulation of homeostatic synaptic plasticity.PLoS ONE (2009) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology clone C-19 rabbit polyclonal Egr-1 antibody was used to perform westn blot in order to investigate the relations between TGFbeta1 and TNFa.Mol Biol Cell (2009) ncbi
not indicated
  • IHC; human
Santa Cruz Biotechnology Egr-1 antibody was used in immunohistochemistry in order to investigate the role of PPAR-gamma in the regulation of bleomycin induced scleroderma.Am J Pathol (2009) ncbi
not indicated
  • WB; human
  • ChIP; human
Santa Cruz anti-Egr-1 was used to perform western blot and ChIP assays in order to show that autophagy in cigarette smoke-induced chronic obstructive pulmonary disease is promoted by Egr-1.PLoS ONE (2008) ncbi
rabbit polyclonal (C-19)
  • IHC; Zonotrichia albicollis
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, Sc-189) was used in immunohistochemistry on Zonotrichia albicollis samples. J Comp Neurol (2008) ncbi
not indicatedSanta Cruz Biotechnology Egr-1 consensus binding oligonucleotides were used in EMSA in order to ascertain whether the downstream signaling pathways mediated by TGF-beta vary in different liver injury models.Am J Pathol (2008) ncbi
not indicated
  • WB; human
  • EMSA; human
Santa Cruz Biotechnology anti-Egr-1 antibody was used in western blot and EMSA to ascertain whether the downstream signaling pathways mediated by TGF-beta vary in different liver injury models.Am J Pathol (2008) ncbi
rabbit polyclonal (588)
  • IHC-F; mouse
Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-110) was used in immunohistochemistry - frozen section on mouse samples. J Comp Neurol (2007) ncbi
not indicated
  • ChIP; human
Santa Cruz Biotechnology anti-Egr-1 antibody was used to perform ChIP assays in order to investigate the molecular mechanisms of HGF-induced cell scattering.EMBO J (2006) ncbi
rabbit polyclonal (C-19) Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-189) was used . J Comp Neurol (2006) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology Egr-1 antibody was used in western blot to study the mechanisms involved in the transcriptional regulation of NHE2 and NHE3.Am J Physiol Gastrointest Liver Physiol (2005) ncbi
not indicated
  • EMSA; human
SCBT EGR-1 (588) antibody was used in EMSA assays to investigate the regulation of VEGF by PGE2J Biol Chem (2005) ncbi
rabbit polyclonal (C-19) Santa Cruz Biotechnology Egr-1 antibody (Santa Cruz Biotechnology, sc-189) was used . J Comp Neurol (2005) ncbi
not indicated
  • WB; human
  • IP; human
  • EMSA; human
  • IC; human
  • ChIP; human
Santa Cruz Biotechnology rabbit polyclonal anti-Egr-1 antibody was used in western blot, immunoprecipitation, EMSA, immunocytochemistry, and ChIP assay to study the effect of Egr-1 on glucagon gene expression in pancreatic alpha cellJ Biol Chem (2005) ncbi
not indicated
  • EMSA; human
  • ChIP; human
Santa Cruz Biotechnology anti-Egr-1 was used in EMSA to detect the interaction between Egr-1 and the SOCS promoter sequences in mouse RAW cells, and in ChIP assay to detect the binding of Egr-1 to the human SOCS-1 promoter in THP-1 human monocytic leukemia cell lineJ Biol Chem (2005) ncbi
Rockland Immunochemicals
rabbit polyclonal
  • ChIP; rat
Rockland Immunochemicals Egr-1 antibody (Rockland Immunochemicals, 600-401-693) was used in chromatin immunoprecipitation on rat samples. Philos Trans R Soc Lond B Biol Sci (2014) ncbi
Invitrogen
rabbit monoclonal (T.160.5)
  • IHC-P; human; 1:50
Invitrogen Egr-1 antibody (ThermoFisher Scientific, T.160.5) was used in immunohistochemistry - paraffin section on human samples at 1:50. Diagn Pathol (2014) ncbi
R and D Systems
goat polyclonal
  • IHC; chicken; 1:1000
R and D Systems Egr-1 antibody (R&D Systems, AF2818) was used in immunohistochemistry on chicken samples at 1:1000. Glia (2014) ncbi
Abnova
not indicated
  • IC; human
Abnova Egr-1 antibody was used in immunocytochemistry in order to demonstrate that self-assembling peptide nanofiber scaffolds accelerate wound healingMol Endocrinol (2008) ncbi
Cell Signaling Technology
rabbit monoclonal (15F7)
  • IHC-P; rat; 1:200
Cell Signaling Technology Egr-1 antibody (Cell Signaling, #4153) was used in immunohistochemistry - paraffin section on rat samples at 1:200. Neuroscience (2015) ncbi
rabbit monoclonal (15F7)
  • WB; human; fig  3
Cell Signaling Technology Egr-1 antibody (Cell Signaling, 4153) was used in western blot on human samples (fig  3). J Biol Chem (2015) ncbi
rabbit monoclonal (15F7)
  • IHC; rat; 1:250
Cell Signaling Technology Egr-1 antibody (Cell Signalling Technology, 15F7) was used in immunohistochemistry on rat samples at 1:250. J Chem Neuroanat (2014) ncbi
not indicated
  • WB; human
Cell Signaling Technology clone 44D5 rabbit monoclonal Egr-1 antibody was used to perform westn blot in order to investigate the relations between TGFbeta1 and TNFa.Mol Biol Cell (2009) ncbi
Articles Reviewed
  1. Peggy Prickaerts et al. (2015). "MK3 modulation affects BMI1-dependent and independent cell cycle check-points".PMID 25853770
  2. W Liu et al. (2015). "Adolescent intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat".PMID 25727639
  3. AiWen Dong et al. (2015). "Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface".PMID 25666625
  4. Jacqueline Salotti et al. (2015). "An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer".PMID 25535333
  5. P J Fitzgerald et al. (2015). "Durable fear memories require PSD-95".PMID 25510511
  6. Rob J C Vogels et al. (2014). "Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases".PMID 25432794
  7. Sarah Hoefflin et al. (2014). "Neuronal expression of SOX2 is enriched in specific hypothalamic cell groups".PMID 25263324
  8. Ian C G Weaver et al. (2014). "The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor".PMID 25135974
  9. Chong Liu et al. (2014). "15d-PGJ₂ decreases PGE₂ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter".PMID 25108236
  10. Catherine E Barrett et al. (2014). "Neonatal melanocortin receptor agonist treatment reduces play fighting and promotes adult attachment in prairie voles in a sex-dependent manner".PMID 24923239
  11. Andy J Fischer et al. (2014). "Reactive microglia and macrophage facilitate the formation of Müller glia-derived retinal progenitors".PMID 24916856
  12. Michael J Bannon et al. (2014). "A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype".PMID 24642598
  13. Jennifer R Kulzer et al. (2014). "A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell".PMID 24439111
  14. Cristina Martinez-Gonzalez et al. (2014). "Divergent motor projections from the pedunculopontine nucleus are differentially regulated in Parkinsonism".PMID 23708060
  15. Anne Laure Schang et al. (2013). "GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene".PMID 23211524
  16. Dasa Dolezalova et al. (2012). "MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells".PMID 22511267
  17. Ashish Bhattacharjee et al. (2010). "Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity".PMID 20861348
  18. Sharon M H Gobes et al. (2009). "Differential responsiveness in brain and behavior to sexually dimorphic long calls in male and female zebra finches".PMID 19637285
  19. Noha Elmouelhi et al. (2009). "Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery".PMID 19326913
  20. Amit Sharma et al. (2009). "Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a".PMID 19307576
  21. Sjoukje D Kuipers et al. (2009). "Selective survival and maturation of adult-born dentate granule cells expressing the immediate early gene Arc/Arg3.1".PMID 19290048
  22. Xiaoying Liu et al. (2009). "Transforming growth factor beta1-mediated activation of the smooth muscle alpha-actin gene in human pulmonary myofibroblasts is inhibited by tumor necrosis factor-alpha via mitogen-activated protein kinase kinase 1-dependent induction of the Egr-1 transcr".PMID 19261809
  23. Minghua Wu et al. (2009). "Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma".PMID 19147827
  24. Zhi Hua Chen et al. (2008). "Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease".PMID 18830406
  25. Donna L Maney et al. (2008). "Estradiol modulates neural responses to song in a seasonal songbird".PMID 18770869
  26. Al Karim Khimji et al. (2008). "Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation".PMID 18753413
  27. Aveline Hewetson et al. (2008). "Progesterone-dependent deoxyribonucleic acid looping between RUSH/SMARCA3 and Egr-1 mediates repression by c-Rel".PMID 18174357
  28. Seigo Suzuki et al. (2007). "Opposing functions of CREB and MKK1 synergistically regulate the geometry of dendritic spines in visual cortex".PMID 17559089
  29. Stefan Grotegut et al. (2006). "Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail".PMID 16858414
  30. Nienke J Terpstra et al. (2006). "Localized brain activation specific to auditory memory in a female songbird".PMID 16374807
  31. Jaleh Malakooti et al. (2005). "Zinc finger transcription factor Egr-1 is involved in stimulation of NHE2 gene expression by phorbol 12-myristate 13-acetate".PMID 15976391
  32. Dawn Bradbury et al. (2005). "Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP2/EP4 receptors and SP-1 transcription factor binding sites".PMID 15970595
  33. Nienke J Terpstra et al. (2005). "Neuronal activation related to auditory perception in the brain of a non-songbird, the ring dove".PMID 15952168
  34. Stéphane Leung-Theung-Long et al. (2005). "Essential interaction of Egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic alpha-cells".PMID 15611055
  35. Justin Mostecki et al. (2005). "Early growth response-1 regulates lipopolysaccharide-induced suppressor of cytokine signaling-1 transcription".PMID 15545275