This is a review about ERK2, based on 396 published articles (read how Labome selects the articles), using ERK2 antibody in all methods. It is aimed to help Labome visitors find the most suited ERK2 antibody.
ERK2 synonym: ERK; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; ERK-2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 2; extracellular signal-regulated kinase 2; mitogen-activated protein kinase 2; p42-MAPK; protein tyrosine kinase ERK2

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  • flow cytometryIn 2010, Qiaoling Liang et al. utilized Santa Cruz Biotechnology ERK2 antibody to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10 [ncbi , more ].
  • immunocytochemistryLijun Xu et al. used Santa Cruz Biotechnology ERK2 antibody to study the role of NNK for lung cancer cell migration and invasion in a mechanism involving phosphorylation of calpains [ncbi , more ] in 2004 and Sunryeo Beom et al. used Santa Cruz Biotechnology ERK2 antibody to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ]. In 2003, Pramod P Naranatt et al. employed Santa Cruz Biotechnology ERK2 antibody to investigate the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway mediated by Kaposi's sarcoma-associated herpesvirus early during infection of target cells (catalog: sc-154) [ncbi , more ].
  • immunohistochemistryIn 2010, Qiaoling Liang et al. utilized Santa Cruz Biotechnology ERK2 antibody to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10 [ncbi , more ]. In 2009, Sam M Janes et al. used Santa Cruz Biotechnology ERK2 antibody to perform immunofluorescence and western blot in order to investigate the earliest events in the commitment of human epidermal keratinocytes to terminal differentiation [ncbi , more ]. In 2008, Hiroshi Honda et al. used Santa Cruz Biotechnology ERK2 antibody to perform immunohistochemistry in dilution 1:50 in order to show that AXL and SHC1 expression disregulation may be associated with pathogenesis of endometriosis [ncbi , more ]. In 2005, Laura Suomalainen et al. employed Santa Cruz Biotechnology ERK2 antibody to study the inhibition effect of sphingosine-1-phosphate on nuclear factor kappa B activation and germ cell apoptosis in the human testis independently of its receptors (catalog: sc-94) [ncbi , more ].
  • immunoprecipitationIn 2010, Sevdalina Nikolova et al. employed Santa Cruz Biotechnology ERK2 antibody to perform western blot in order to study the function of phosphodiesterase 6 subunits in idiopathic pulmonary fibrosis [ncbi , more ]. In 2005, Guoyong Yin et al. utilized Santa Cruz Biotechnology ERK2 antibody to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. In 2004, Mizuo Mifune et al. utilized Santa Cruz Biotechnology ERK2 antibody to study the molecular mechanisms downstream of BTC involved in mediating vascular remodeling [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was applied in 2003 to study that extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus [ncbi , more ], to investigate the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway mediated by Kaposi's sarcoma-associated herpesvirus early during infection of target cells (catalog: sc-154) [ncbi , more ]and to demonstrate RSK2 activity is regulated by its interaction with PEA-15 [ncbi , more ]. Elena Diaz-Rodriguez et al. employed Santa Cruz Biotechnology ERK2 antibody to study the effect of a dominant negative form of Erk2 on TACE phosphorylation at T735 [ncbi , more ] in 2002 and Marcus Buschbeck et al. used Santa Cruz Biotechnology ERK2 antibody to study the ERK5 signaling pathway regulation by PTP-SL [ncbi , more ]. In 2001, S Yamasaki et al. utilized Santa Cruz Biotechnology ERK2 antibody to study the T cell receptor signaling regulation by docking protein Gab2 [ncbi , more ]. In 2000, D L Persons et al. employed Santa Cruz Biotechnology ERK2 antibody to precipitate ERK1/2 complex to study the cisplatin-induced activation of ERK1/2 and inhibition of cisplatin-induced ERK1/2 activity by PD98059 [ncbi , more ].
  • western blotIn 2011, Carmine Settembre et al. employed Santa Cruz Biotechnology ERK2 antibody to perform western blot in order to show that lysosomal biogenesis could be induced by TFEB and lead to autophagy [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was applied in 2010 to perform western blot, immunohistochemistry and flow cytometry in order to study the signaling mechanism in the resistance of T cells from asthmatic patients against suppression by TGFbeta and IL-10 [ncbi , more ], to perform western blot in order to study the roles of RBBP9 as a tumor-associated serine hydrolase to pancreatic neoplasia [ncbi , more ]and to perform western blot in order to study the role of cdc6 in chromosomal segregation mediated by cdk1 and separase [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was utilized in 2009 to perform western blot in order to study the function of snail1 in controlling bone mass during osteoblast differentiation [ncbi , more ], to study the role for proepithelin in stimulating the migration, proliferation, and anchorage-independent growth of prostate cancer cells [ncbi , more ], to demonstrate that Cold-Inducible RNA-Binding Protein bypassed replicative senescence in primary cells through extracellular signal-regulated kinase 1 and 2 activation [ncbi , more ], to combine computational simulations, experimental testing of simulation results, and finally reverse engineering of a protein interaction network to define potential therapeutic strategies for de novo trastuzumab resistant breast cancer [ncbi , more ], to carry out western blot analysis in order to investigate the signal cross talk between ErbB2 and PR receptor and the effect on breast cancer growth [ncbi , more ], to study the role of F-BAR and SH2 domains of Fes protein tyrosine kinase in regulating FcRI Pathway [ncbi , more ], to perform western blot in order to show the role of S-glutathionylation of STAT3 in STAT3 signaling [ncbi , more ], to detect pERK in western blot in order to demonstrate that the MAPK/CREB cascade and the STAT-3 signaling pathway mediate H-IL-6-activated neurogenesis and gliogenesis [ncbi , more ], to perform immunofluorescence and western blot in order to investigate the earliest events in the commitment of human epidermal keratinocytes to terminal differentiation [ncbi , more ]and to investigate the role of sproutys in the regulation angiogenesis and ischemia in mice [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was utilized in 2008 to investigate molecular correlates of IA consolidation in the hippocampus and the basolateral amygdala structures and their relation to NMDA receptors (NMDArs) and beta-adrenergic receptors (beta-ADrs) [ncbi , more ], to study the pathogenesis of Joubert syndrome and the role of the Ahi1-Hap1 complex in early brain development [ncbi , more ], to study the role of MMP-2 inhibition in tumor cells by targeting angiogenic components of tumor growth [ncbi , more ], to perform western blot in order to investigate the relations between SOCS3 and migratory of lung cancer [ncbi , more ], to perform western blot in order to show that periodontal ligament fibroblasts can maintain an equilibrium of the plasminogen activator system in the presence of platelet-derived growth factor isoforms [ncbi , more ], to study the contribution of c-Jun to ccl2 transcriptional regulation in genetically modified mouse fibroblasts and in human cells (catalog: sc-6233) [ncbi , more ], to investigate ET receptor-mediated activation of the mitogen-activated protein kinase (MAPK) pathway in human choriocarcinoma [ncbi , more ], to demonstrate that Gq coupling of the AT1 receptor is essential for the EGFR transactivation and subsequent VSMC hypertrophy induced by AngII [ncbi , more ], to perform western blot in order to investigate the role of MT1-MMP-TIMP-2 interaction in controlling cell functions [ncbi , more ], to perform western blot in order to study the role of uPA binding in UPAR localization to lipid rafts and receptor microdomain composition [ncbi , more ]and to perform western blot in order to show that vascular integrity and angiogenesis are regulated by miR-126 [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was used in 2007 to examine the activity of different members of the phosphodiesterase (PDE) family in primary human lung fibroblasts [ncbi , more ], to identify p18 (Hamlet) as a new cell-fate regulator [ncbi , more ], to demonstrate that CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha [ncbi , more ], to study the essential involvement of the adaptor protein Act1 in IL-17 receptor (IL-17R) signaling and IL-17-dependent immune responses [ncbi , more ], to show that Mxi2 has profound effects on ERK1/2 nucleocytoplasmic distribution, promoting their accumulation in the nucleus [ncbi , more ], to study the role of MNAR in 17beta-estradiol (E2) induced activation of the phosphatidylinositol 3-kinase (PI3K) /Akt pathway [ncbi , more ]and to study the role of LIF in Stat3 activation in mouse mammary tumors [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was used in 2006 to study the antagonizing of the receptor-type protein tyrosine phosphatase J for effects of RET-derived oncoproteins [ncbi , more ], to demonstrate that NudC-like protein (NudCL) plays an essential role in mitosis and contributes to stabilization of the dynein complex [ncbi , more ], to study the roles for furin-, ADAM 10-, and gamma-secretase in cleavage of a receptor tyrosine phosphatase and regulation of beta-catenin's transcriptional activity in human cells [ncbi , more ], to study the effect of RET/PTC3 on the Erk8 mitogen-activated protein (MAP) kinase [ncbi , more ], to study the roles of ATF3 in both cell death and cell cycle regulation [ncbi , more ], to study heterogeneous de novo missense mutations in three genes within the mitogen-activated protein kinase (MAPK) pathway [ncbi , more ], to study the interaction between the receptor protein-tyrosine phosphatase PTP and IQGAP1 [ncbi , more ], to investigate whether the signals generated by Ras proteins were affected by microlocalization and its important biological outcomes [ncbi , more ]and to demonstrate that arrestin-2 and GRK5 (G protein-coupled receptor kinase 5) play a negative role in TLR4 signaling in Raw264.7 macrophages [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was used in 2005 to study the role of CCN in ovarian carcinomas [ncbi , more ], to detect total ERK2 in PAK4 knockdown (RNAi) cells untreated or treated with TNFalpha+CHX [ncbi , more ], to study the cellular and molecular function of a novel interferon- and LPS-inducible gene designated FLN29 that acts as a negative regulator in TLR signaling [ncbi , more ], to study a novel link between GILZ and regulation of epithelial sodium transport through modulation of ERK signaling [ncbi , more ], to demonstrate the opposing roles of SphK1 and SphK2 in the regulation of ceramide biosynthesis [ncbi , more ], to demonstrate that HNE increases HO-1 mRNA, protein, and activity in pulmonary epithelial cells through ERK pathway [ncbi , more ], to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ], to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection [ncbi , more ], to study the role of uPAR in cross-talk between FPR and alphavbeta5 [ncbi , more ], to study the inhibition of matrix metalloproteinase-9 expression by ascochlorin [ncbi , more ], to study ERK2 and p38 involvement in platelet adhesion to collagen [ncbi , more ], to study the immortalization of bovine lens epithelial cells by human telomerase reverse transcriptase [ncbi , more ], to study the direct interaction between human CNK1 and Raf-1 [ncbi , more ], to investigate the consequences of Xrcc3 overexpression in terms of cell cycle progression, Rad51-related homologous recombinational repair, and cell survival after cisplatin treatment in the breast cancer cell line MCF-7 [ncbi , more ], to study COLO-357 cell growth inhibition by TGF beta1 [ncbi , more ], to study the effect of enhanced p38 MAPK activity on endothelial cell function [ncbi , more ], to explore mechanisms for leptin activity in the heart [ncbi , more ], to study the biological function of TRAIL induced apoptosis in human colon cells (catalog: sc-7383,sc-1647) [ncbi , more ], to demonstrate that deletion of MEF GnT-V resulted in enhanced integrin clustering and activation of alpha5beta1 transcription by protein kinase C signaling [ncbi , more ], to study tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells [ncbi , more ], to study the role of Dmp1 in Ras-Raf-Arf signaling [ncbi , more ], to study the role for the interleukins 2 and 15 in regulating Ets1 expression in human natural killer cells [ncbi , more ], to study the physiological role of ER palmitoylation in the receptor localization to the cell membrane and in the regulation of the E2-induced cell proliferation [ncbi , more ]and to study the effect of receptor-type protein-tyrosine phosphatase-kappa on epidermal growth factor receptor function [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was used in 2004 to study the physical interaction between Runx2 and Stat3beta enhanced by GH and downregulateing the transcriptional properties of this key osteogenic regulator (catalog: sc-154) [ncbi , more ], to study the function of Gs-coupled receptors to induce activation of H-Ras and the ERK1/2 MAP kinases by an Epac- and Ca2+-controlled pathway [ncbi , more ], to study the role of Raf-1 activation during cell stress [ncbi , more ], to demonstrate that IGF-1 and its receptor in regulate post-translational changes in RUNX2 to activate DNA binding in proliferating EC [ncbi , more ], to detect ERK2 in NIH 3T3 cells transiently transfected with vector, RACK1, or mutant RACK1, and HEK 293 cells transfected with RACK1 siRNAs [ncbi , more ], to study the molecular mechanisms downstream of BTC involved in mediating vascular remodeling [ncbi , more ], to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ], to detect extracellular signal-regulated kinase 2 in Panc-1 cells [ncbi , more ], to study a novel BASH N terminus-associated protein (BNAS2) [ncbi , more ], to study the effect of Pyk2 on epidermal growth factor and c-Src-induced Stat3 activation in HeLa cell [ncbi , more ], to detect Erk2 as a loading control in LNCaP cells with FKHR transfection [ncbi , more ], to detect the phospho-p42 MAPK in differentiated and non-differentiated N1E-115-NT1-EGFP cells stimulated with no agonist or JMV 449 [ncbi , more ]and to study the effect of multiple protein kinases and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription on constitutive and interleukin-1-inducible phosphorylation of p65 NF- B at serine 536 [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was used in 2003 to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells [ncbi , more ], to study the roles of Janus kinase 2 and calcium for angiotensin II-dependent activation of steroidogenic acute regulatory protein transcription in H295R human adrenocortical cells [ncbi , more ], to study the effect of N-acetylglucosaminyltransferase V expression levels on cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways in HT1080 human fibrosarcoma cells [ncbi , more ], to study the Initiation of CD38 signaling in T Cells within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor [ncbi , more ], to study the protective role of SCP and SRP against hypoxia/rexygenation injury in rat neonatal cardiomyocytes [ncbi , more ], to demonstrate that ERK1/2 are the Raf effectors for suppression of integrin activation [ncbi , more ], to study the interaction of calcium/calmodulin-dependent protein kinase II with Raf-1 and the effect of it on integrin-stimulated ERK activation [ncbi , more ], to study the effects of TL1A-induced NF- B and c-IAP2 on DR3-mediated apoptosis in TF-1 cells [ncbi , more ], to investigate the activation of ERK1/2 in primary human melanocytes isolated from neonatal foreskins and in the human melanoma SK-MEL-24 and SK-MEL-28 cell lines [ncbi , more ], to study the function of pancreatic bile salt-dependent lipase to induce smooth muscle cells proliferation [ncbi , more ], to study whether RKIP functions as a suppressor of prostate cancer metastasis in human prostate cancer cells [ncbi , more ], to study the interaction of Bcr kinase and AF-6 and the effects of them on Ras signaling [ncbi , more ], to study the expression, function, and signaling pathways of PCDGF in human MM [ncbi , more ], to detect ERK and phosphorylated ERK in HepG2 cells expressing CYP2E1 or CYP3A4 [ncbi , more ], to study the effect of leukocyte-endothelium interaction on SDF-1-dependent polarization of CXCR4 [ncbi , more ], to study the GIPC interaction with beta1-adrenergic receptor and its regulation on beta1-adrenergic receptor-mediated ERK activation [ncbi , more ], to study the role of Lipocalin-type prostaglandin D2 synthase (L-PGDS) in maintaining the proper equilibrium between proliferation and apoptosis [ncbi , more ], to study the pathway for platelet-derived growth factor to induce the beta-gamma-secretase-mediated cleavage of alzheimer's amyloid precursor protein [ncbi , more ], to study the role of Raf-1 and Bcl-2 in breast cancer drug resistance [ncbi , more ], to study that extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus [ncbi , more ], to investigate the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway mediated by Kaposi's sarcoma-associated herpesvirus early during infection of target cells (catalog: sc-154) [ncbi , more ], to study the contributions of the different downstream pathways of IGF-IR to IGF-IR-mediated radioresistance [ncbi , more ]and to detect the protein levels of Erk-2 in human Jurkat E6-1 T cells [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was employed in 2002 to study the role of SAP in murine CD150 (SLAM) mediated T-cell proliferation and interferon gamma production [ncbi , more ], to determine if IGFBP-3 might enhance IGF action by influencing intracellular signaling events downstream of the IGF receptor [ncbi , more ], to detect ERK1/2 in A2780 and OVCAR5 ovarian cancer cell lines and human HEK293 cells [ncbi , more ], to further elucidate the activation mechanism for intracellular signaling mediated by interaction between Dok1 and phosphorylated RET [ncbi , more ], to study the ERK5 signaling pathway regulation by PTP-SL [ncbi , more ], to detect total and phospho-ERK2 in human B lymphoma cell line ramos 2G6 incubated with anti-CD45, following stimulation by IL-4 and anti-CD40 [ncbi , more ], to detect ERK2 expression levels in human HepG2 cells [ncbi , more ], to study the effects of insulin-like growth factor-binding protein-3 on the IGF-I signaling pathway [ncbi , more ], to detect ERK2 in D5 and vector HEK293 cells untreated or treated with insulin [ncbi , more ], to detect ERK2 in A549 cells [ncbi , more ], to detect ERK in human orbital fibroblasts [ncbi , more ]and to exploit EphA2 as a therapeutic target of cancer [ncbi , more ]. Santa Cruz Biotechnology ERK2 antibody was applied in 2001 to study the T cell receptor signaling regulation by docking protein Gab2 [ncbi , more ], to demonstrate the causal relationship between PTEN loss and overexpression of Bcl-2 in prostate cancer [ncbi , more ], to study the expression, regulation, and tumor suppressor properties of BTG2 in prostate cells [ncbi , more ], to study activation of nuclear factor-kappa B by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein in the MEEKK1/p38 MAP kinase pathway [ncbi , more ]and to study migration and signal transduction in corneal epithelial cells [ncbi , more ]. In 2000, D L Persons et al. employed Santa Cruz Biotechnology ERK2 antibody to precipitate ERK1/2 complex to study the cisplatin-induced activation of ERK1/2 and inhibition of cisplatin-induced ERK1/2 activity by PD98059 [ncbi , more ].
  • immunocytochemistryIn 2001, Y Mazaki et al. utilized EMD Millipore ERK2 antibody to investigate the function of the ARFGAP (ADP-ribosylation factor GTPase-activating protein) Git2-short/KIAA0148 associated with paxillin during integrin signaling [ncbi , more ].
  • immunohistochemistryIn 2009, Catherine W Morgans et al. employed EMD Millipore ERK2 antibody to immunohistochemistry in order to research reduced neurotransmission and altered synaptic vesicle protein expression in the retina for loss of synaptic vesicle protein SV2B [ncbi , more ].
  • western blotIn 2010, Mary Kay Lobo et al. utilized EMD Millipore ERK2 antibody to carry out western blot assays in order to investigate the effect of lossing BDNF receptor in different neurons on control of cocaine reward [ncbi , more ]. EMD Millipore ERK2 antibody was applied in 2009 to perform western blot in order to show that rapamycin treatment can lead to the transactivation of the EGFR [ncbi , more ], to detect ERK in western blot in order to demonstrate that the MAPK/CREB cascade and the STAT-3 signaling pathway mediate H-IL-6-activated neurogenesis and gliogenesis [ncbi , more ], to perform western blot in order to study the oncogenic behavior of the RON receptor tyrosine kinase in breast epithelial cells [ncbi , more ]and to carry out immunoblotting assays in order to investigate the mechanism of ERK-dependent transactivation of the EGFR by G protein-dependent and beta-arrestin-dependent pathways in vascular smooth muscle cells [ncbi , more ]. Xinjing Luo et al. utilized EMD Millipore ERK2 antibody to investigate the effects of extracellular HSP70 on the production of RA-associated cytokines in fibroblast-like synoviocytes from patients with RA [ncbi , more ] in 2008 and Glenn E Schafe et al. used EMD Millipore ERK2 antibody to demonstrate that ERK/MAPK activation is required for LTP in anatomically defined regions of the LA, in vivo [ncbi , more ]. In 2006, Anna Moshnikova et al. utilized EMD Millipore ERK2 antibody to detect ERK expression in human A549 lung adenocarcinoma cells [ncbi , more ]. In 2005, Ken L Chambliss et al. employed EMD Millipore ERK2 antibody to dissect the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol [ncbi , more ]. In 2004, Mireille Toy-Miou-Leong et al. employed EMD Millipore ERK2 antibody to detect the total p42 MAPK in differentiated and non-differentiated N1E-115-NT1-EGFP cells stimulated with no agonist or JMV 449 [ncbi , more ]. C J Grill et al. used EMD Millipore ERK2 antibody to determine if IGFBP-3 might enhance IGF action by influencing intracellular signaling events downstream of the IGF receptor [ncbi , more ] in 2002 and Patrick A Kiely et al. used EMD Millipore ERK2 antibody to study the role for the interaction between RACK1 and insulin-like growth factor 1 (IGF-1) receptor in regulating IGF-1-mediated Akt activation and protection from cell death [ncbi , more ]. C Wu et al. used EMD Millipore ERK2 antibody to study Rap1 signaling activation in endosomes by nerve growth factor [ncbi , more ] in 2001 and E L Deszo et al. used EMD Millipore ERK2 antibody to study the role of CD45 in monocytic cells (catalog: 06-182) [ncbi , more ].
  • western blotIn 2009, Ozgur Sahin et al. utilized R and D Systems ERK2 antibody to combine computational simulations, experimental testing of simulation results, and finally reverse engineering of a protein interaction network to define potential therapeutic strategies for de novo trastuzumab resistant breast cancer (catalog: AF1018) [ncbi , more ].
  • immunohistochemistryIn 2010, Mehrnoosh Saghizadeh et al. used Abcam ERK2 antibody to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas (catalog: ab4819) [ncbi , more ].
  • western blotIn 2009, Emma E Frost et al. used Abcam ERK2 antibody to carry out western blot analysis in order to investigate the role for PDGF-A activated ERK signaling pathway in the regulation of oligodendrocyte progenitor cell migration [ncbi , more ].
  • ChIP assayIn 2008, E Lecona et al. utilized Cell Signaling Technology ERK2 antibody to demonstrate that annexin A1 promoter activity is controlled by a functional cooperation between p53 and factors binding to the proximal CCAAT box [ncbi , more ].
  • EMSAIn 2005, Nikos Tapinos et al. utilized Cell Signaling Technology ERK2 antibody to investigate the activation of Erk1/2 by intracellular M. leprae [ncbi , more ].
  • flow cytometryIn 2005, Carolyn J Broccardo et al. applied Cell Signaling Technology ERK2 antibody to probe the control elements of the CYP1A1 switching module in H4IIE hepatoma cells [ncbi , more ]. In 2003, Jeroen P Roose et al. applied Cell Signaling Technology ERK2 antibody to detect the protein levels of phosphorylated Erk-2, and in flow cytometry to analyze for phospho-p44/42 MAP kinase (Thr204/Tyr204) in human Jurkat E6-1 T cells [ncbi , more ].
  • immunocytochemistryIn 2012, Devendra Singh et al. used Cell Signaling Technology ERK2 antibody to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients [ncbi , more ]. In 2005, Guoyong Yin et al. utilized Cell Signaling Technology ERK2 antibody to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. In 2004, Sunryeo Beom et al. employed Cell Signaling Technology ERK2 antibody to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ]. J Albanell et al. utilized Cell Signaling Technology ERK2 antibody to study the expression of activated ERK1/2 in head and neck squamous carcinoma and their relationship with EGF receptor/TGF-alpha expression [ncbi , more ] in 2001 and M J Marinissen et al. used Cell Signaling Technology ERK2 antibody to study Rho-ERK6 gene expression regulation pathway [ncbi , more ].
  • immunohistochemistryIn 2012, Devendra Singh et al. used Cell Signaling Technology ERK2 antibody to perform immunohistochemistry and immunocytochemistry in order to show that FGFR-TACC fusion happened in specific GBM patients [ncbi , more ]. In 2010, Mehrnoosh Saghizadeh et al. utilized Cell Signaling Technology ERK2 antibody to perform immunohistochemistry in order to study the roles of MMP-10 and CTSF in impaired wound healing in diabetic corneas [ncbi , more ]. Cell Signaling Technology ERK2 antibody was used in 2009 to incubate the sections of the pancreas in order to confirm the Hh pathway was activate in human pancreatic and metastatic cancer [ncbi , more ], to perform immunohistochemistry and western blot in order to find out the new function of HDAC3 in shuttling phosphorylated TR2 to PML [ncbi , more ], to perform immunohistochemistry in order to study the function of the fixative in the immunohistochemical detection of phosphoproteins [ncbi , more ]and to demonstrate that FGF18 provided both directional and proliferative cues to chondrocytes in the developing upper respiratory tract by up-regulating Sox9 expression [ncbi , more ]. Aida Maddahi et al. applied Cell Signaling Technology ERK2 antibody to study the role of the MEK/ERK pathway in receptor expression following ischemic brain injury using the specific MEK1 inhibitor U0126 [ncbi , more ] in 2008 and Xing Yun Song et al. used Cell Signaling Technology ERK2 antibody to study the role of BDNF in the regeneration of central axons of ascending sensory [ncbi , more ]. Ye Zhou et al. applied Cell Signaling Technology ERK2 antibody to study the relationship between FPR expression and the biologic behavior of glioma cells [ncbi , more ] in 2005 and Laura Suomalainen et al. used Cell Signaling Technology ERK2 antibody to study the inhibition effect of sphingosine-1-phosphate on nuclear factor kappa B activation and germ cell apoptosis in the human testis independently of its receptors [ncbi , more ]. Shinji Yamamoto et al. used Cell Signaling Technology ERK2 antibody to study the role of activated Akt expression in prognosis of pancreatic ductal adenocarcinoma [ncbi , more ] in 2004 and Timothy J King et al. used Cell Signaling Technology ERK2 antibody to study the role of Cx32/GJIC in radiation-induced tumorigenesis of the liver [ncbi , more ]. In 2003, Yuichi Oike et al. employed Cell Signaling Technology ERK2 antibody to study the role of AGF in epidermal keratinocytes [ncbi , more ]. In 2002, Shazli N Malik et al. used Cell Signaling Technology ERK2 antibody to study the expression of phospho-specific Akt in human prostate cancer [ncbi , more ]. In 2001, J Albanell et al. utilized Cell Signaling Technology ERK2 antibody to study the expression of activated ERK1/2 in head and neck squamous carcinoma and their relationship with EGF receptor/TGF-alpha expression [ncbi , more ].
  • immunoprecipitationJianrong Wang et al. used Cell Signaling Technology ERK2 antibody to study the role of Beclin 1 in the regulation of autophagy [ncbi , more ] in 2009 and Jean Philippe Couture et al. used Cell Signaling Technology ERK2 antibody to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation [ncbi , more ]. In 2008, Jiaxu Wang et al. used Cell Signaling Technology ERK2 antibody to study the role of Jab1 in mediating EGFR signaling [ncbi , more ]. In 2006, Soon Young Choi et al. employed Cell Signaling Technology ERK2 antibody to detect MAPK and phospho-MAPK in NCI-H1299 cells [ncbi , more ]. Alex C Minella et al. applied Cell Signaling Technology ERK2 antibody to investigate the regulatoin of Fbw7-mediated cyclin E proteolysis by Ras [ncbi , more ] in 2005 and Scott K Kuwada et al. used Cell Signaling Technology ERK2 antibody to study HER-2 down-regulation in colon cancer cells [ncbi , more ]. In 2004, Mizuo Mifune et al. utilized Cell Signaling Technology ERK2 antibody to study the molecular mechanisms downstream of BTC involved in mediating vascular remodeling [ncbi , more ]. In 2002, John K G Crean et al. utilized Cell Signaling Technology ERK2 antibody to study the role of p42/44 MAPK and protein kinase B in CTGF induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells [ncbi , more ]. Cell Signaling Technology ERK2 antibody was used in 2001 to study the role of 7 nicotinic receptor in transduing signals to phosphatidylinositol 3-kinase to block a-amyloid-induced neurotoxicity [ncbi , more ], to study p38 MAP kinase activation in keratinocytes [ncbi , more ]and to study the effect of SNT1 on ERK activation and neuronal differentiation in PC12 cells [ncbi , more ].
  • western blotIn 2013, Uma Karthika Rajarajacholan et al. employed Cell Signaling Technology ERK2 antibody to perform western blot in order to study how ING1a induced senescence [ncbi , more ]. In 2012, Jesse G Zalatan et al. utilized Cell Signaling Technology ERK2 antibody to perform western blot in order to show that MAPK misactivation could be Insulated by Ste5 conformational changes [ncbi , more ]. Cell Signaling Technology ERK2 antibody was used in 2011 to perform western blot in order to investigate ubiquitin signaling mechanism that orchestrates in Golgi morphogenesis and dendrite elaboration [ncbi , more ], to perform western blot in order to study the interaction between dehydroepiandrosterone and nerve growth factor (NGF) receptors [ncbi , more ]and to perform western blot in order to show that lysosomal biogenesis could be induced by TFEB and lead to autophagy [ncbi , more ]. Cell Signaling Technology ERK2 antibody was used in 2010 to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells [ncbi , more ], to carry out western blot analysis in order to investigate the precise contribution of 4E-BPs to mTORC1 signaling [ncbi , more ]and to perform western blot in order to study the role of microRNA-7 in tongue squamous cell carcinoma cells [ncbi , more ]. Cell Signaling Technology ERK2 antibody was utilized in 2009 to characterize the role of ERBB4 mutations in melanoma [ncbi , more ], to perform western blot in order to study the important role of GRK4 in D3 receptor's signaling in human proximal tubule cells [ncbi , more ], to study the role of Beclin 1 in the regulation of autophagy [ncbi , more ], to investigate the role of DLK in the regulation of 3T3-L1 adipocyte differentiation [ncbi , more ], to investigate the role of BRAF in the regulation of RAF-MEK signaling pathway [ncbi , more ], to study the role for prostate specific membrane antigen in regulating the expression of IL-6 and CCL5 in prostate tumour cells [ncbi , more ], to perform western blot in order to study cytosolic PLA2 in CTL-mediated immunopathology of celiac disease [ncbi , more ], to study the effect of Lipocalin 2 on breast cancer progression [ncbi , more ], to study the role of pro-inflammatory peptide LL-37 in the ovarian tumor progression [ncbi , more ], to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis [ncbi , more ], to carry out western blot analysis in order to investigate the role for AEG1 in regulating Hepatocellular carcinoma pathogenesis [ncbi , more ], to perform immunohistochemistry and western blot in order to find out the new function of HDAC3 in shuttling phosphorylated TR2 to PML [ncbi , more ], to study the effect of calcitonin gene-related peptide on proliferation of alveolar epithelial cells [ncbi , more ], to perform immunoblotting in order to study the regulation of BAD phosphorylation involved in beta-arrestin-2 mediated anti-apoptotic effects [ncbi , more ], to analyze the early events that are specifically induced by the apical supply of PPM and to determine the molecular mechanisms of PPM sensing in enterocytes [ncbi , more ], to perform western blot in order to show that rapamycin treatment can lead to the transactivation of the EGFR [ncbi , more ], to carry out western blot analysis in order to investigate the regulation of adipocyte glucose transport by ClipR-59 mediated Akt cellular compartmentalization [ncbi , more ], to study the role for bone morphogenetic protein 2 in inducing pulmonary angiogenesis and its mechanism [ncbi , more ], to test the hypothesis that additional RAS mutations outside of codons 12, 13, and 61 may account for oncogenesis in myeloid malignancies [ncbi , more ], to study how ubiquitination and ubiquitin sensing proteins regulate cellular and organismal survival [ncbi , more ], to perform western blot in order to show the role of CK2B in apoptosis resistance and cell proliferation in endometrial carcinoma [ncbi , more ], to perform western blot in order to prove that the mGluR2 activation plays an important role in signal transduction pathways and neuronal cell survival [ncbi , more ], to indicate that SUMOylation is mediated through reduced CDK7-induced phosphorylation of SF-1 [ncbi , more ], to study the role for Hsp72 in suppression of the oncogene-induced senescence [ncbi , more ], to investigate potential links between decreased BRCA1 levels and responses to Tam in ER-positive human breast cancer cell lines (T47D and ZR-75-1) [ncbi , more ], to show that Hsp90 co-chaperone CDC37 can maintain the oncogenic protein kinase clients [ncbi , more ], to study the role for RhoE in keratinocyte differentiation and stratification [ncbi , more ]and to perform western blot in order to show that autophagy is induced by stent-eluting drugs sirolimus and paclitaxel to suppress healing of the endothelium [ncbi , more ]. Cell Signaling Technology ERK2 antibody was employed in 2008 to investigate the effect of a C-terminally tethered G protein alpha-subunit on the recycling rate and post-endocytic fate of the beta2AR receptor [ncbi , more ], to demonstrate that IL-19 can be induced by inflammatory cytokines and inflammatory stimuli [ncbi , more ], to study the efficacy of lapatinib for preventing the outgrowth of breast cancer cells in the brain in a mouse xenograft model of brain metastasis [ncbi , more ], to study the pathogenesis of Joubert syndrome and the role of the Ahi1-Hap1 complex in early brain development [ncbi , more ], to perform western blot in order to study the role of calmodulin kinase in ligand-independent EGFR degradation in pregnancy [ncbi , more ], to demonstrate that annexin A1 promoter activity is controlled by a functional cooperation between p53 and factors binding to the proximal CCAAT box [ncbi , more ], to study the role of Jab1 in mediating EGFR signaling [ncbi , more ], to study the effect of Helicobacter pylori infection on plasminogen activator inhibitor 1 production [ncbi , more ], to determine the effects of the NO-releasing prodrug O2- (2, 4-dinitrophenyl) 1- [ (4-ethoxycarbonyl) piperazin-1-yl]diazen-1-ium-1, 2-diolate (JS-K) on breast cancer invasion [ncbi , more ], to perform western blot in order to study the role of Raf-1 in glioma formation [ncbi , more ], to perform western blot in order to show that neovessel development can be regulated by fibronectin fibrillogenesis [ncbi , more ], to perform western blot in order to show that periodontal ligament fibroblasts can maintain an equilibrium of the plasminogen activator system in the presence of platelet-derived growth factor isoforms [ncbi , more ], to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines [ncbi , more ], to investigate the mechanism of how insulin signaling pathway and glucose metabolism were affected by the inhibitor of nuclear factor-kappa B kinase (IKK) in human skeletal muscl [ncbi , more ], to study the effect of human herpesvirus 8 chemokines on endothelial survival and virus replication [ncbi , more ], to perform western blot in order to study the signification of the expression of Sdpr and Fhl1 in tumors of the breast,kidney and prostate [ncbi , more ], to determine whether the key elements of the endocannabinoid signalling system are expressed in the synovia of patients with osteoarthritis (OA) or RA [ncbi , more ], to investigate the effects of Inmunoferon-active principle (AM3) on human monocyte-derived DCs (MDDCs) [ncbi , more ], to study the regulation and the role of NAG-1 expression in VES-treated PC-3 human prostate carcinoma cells [ncbi , more ], to study the mechanisms by which GH and/or IGF-1 regulate sodium and water balance remain [ncbi , more ], to investigate ET receptor-mediated activation of the mitogen-activated protein kinase (MAPK) pathway in human choriocarcinoma [ncbi , more ], to examine the effects of dynamic compression on levels of expression of iNOS and COX-2 and involvement of the p38 mitogen-activated protein kinase (MAPK) pathway [ncbi , more ], to study the role of PAX4 in the beta-cell differentiation of human embryonic stem cells [ncbi , more ], to demonstrate that ERK/MAPK activation is required for LTP in anatomically defined regions of the LA, in vivo [ncbi , more ], to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation [ncbi , more ], to study the roles for mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells [ncbi , more ], to demonstrate that lithium suppresses Smad3/4-dependent TGF-beta-responsive gene transactivation [ncbi , more ], to perform immunoblotting in order to study the molecular mechanisms of autoactivation happened in the catalytic domain of anaplastic lymphoma kinase [ncbi , more ], to investigate the effects of CB2 receptor agonists on TNF-alpha-induced proliferation, migration, and signal transduction [ncbi , more ], to perform western blot in order to investigate the role of MT1-MMP-TIMP-2 interaction in controlling cell functions [ncbi , more ], to perform western blot in order to study the role of uPA binding in UPAR localization to lipid rafts and receptor microdomain composition [ncbi , more ]and to perform western blot in order to show that thioredoxin is an IFN-gamma-induced factor and plays a role for cytokine production [ncbi , more , fig ]. Cell Signaling Technology ERK2 antibody was utilized in 2007 to study the role of glycosylation in the NK1R in human colonic epithelial cell line [ncbi , more ], to phosphorylated ERK1/2 in platelets from patients during AMI [ncbi , more ], to assesse the effects of cryptotanshinone on macrophage chemotaxis [ncbi , more ], to study the role of Ubc13 in TNF receptor-associated factor (TRAF) mediated inflammatory responses [ncbi , more ], to identify p18 (Hamlet) as a new cell-fate regulator [ncbi , more ], to study the role of OSBP in regulating of hepatic TG metabolism and insulin signaling pathways [ncbi , more ], to perform western blot in order to show that the Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling can activate the transcription factor Elk-1 [ncbi , more ]and to study the role of acetylation, one of the main post-translational regulatory mechanisms, in regulating Fli1 activity in human dermal fibroblast [ncbi , more ]. Cell Signaling Technology ERK2 antibody was employed in 2006 to examine ERK1/2 phosphorylation in human breast cancer cell lines MDA-MB231 and MCF-7 [ncbi , more ], to investigate the activation of ERK1/2 by FGF19 promoter in human CE cells [ncbi , more ], to detect phosphorylated ERK protein in human HT-29 colon cells [ncbi , more ], to develop an assay for monitoring Trk activation in response to their cognate ligands [ncbi , more ], to study the antagonizing of the receptor-type protein tyrosine phosphatase J for effects of RET-derived oncoproteins [ncbi , more ], to study selective modulation of Gbetagamma subunit functions by small molecules [ncbi , more ], to detect Erk2 and phosphorylated Erk2 in human HeLa cells [ncbi , more ], to detect ERK and phosphorylated ERK in RAW264.7 and CL-2 cells activated with IFN-gamma or LPS [ncbi , more ], to study the effect of RET/PTC3 on the Erk8 mitogen-activated protein (MAP) kinase [ncbi , more ], to detect the phosphorylation of p42/44 MAPK in primary neonatal human melanocytes [ncbi , more ], to verify that exercise training and calorie restriction increase SREBP-1 expression [ncbi , more ], to perform western blot in order to study the mechanism of anti-HCV by TLR7 [ncbi , more ], to study heterogeneous de novo missense mutations in three genes within the mitogen-activated protein kinase (MAPK) pathway [ncbi , more ], to characterize the antiangiogenic and antitumor activity of the hydroxamic derivative LBH589 [ncbi , more ], to detect ERK and activation of ERK in human renal carcinoma ACHN cells [ncbi , more ], to study the role of epidermal growth factor in transforming growth factor beta signaling and growth suppression [ncbi , more ], to detect MAPK and phospho-MAPK in NCI-H1299 cells [ncbi , more ], to study the interaction between the receptor protein-tyrosine phosphatase PTP and IQGAP1 [ncbi , more ], to study the role for the effect of HER-2/neu on RECK expression in promoting cell invasion [ncbi , more ], to determine whether individuals make antibodies to study the roles of Raf kinases in L&M and plasticity [ncbi , more ], to domenstrate that proline 326 in the C terminus of murine CX3CR1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of Akt and extracellular signal-regulated kinase in Chinese hamster ovary cells [ncbi , more ]and to study the expression and role of Nrdp1 in cancer [ncbi , more ]. Cell Signaling Technology ERK2 antibody was used in 2005 to detect phospho-ERK2 in PAK4 knockdown (RNAi) cells untreated or treated with TNFalpha+CHX [ncbi , more ], to study the cellular and molecular function of a novel interferon- and LPS-inducible gene designated FLN29 that acts as a negative regulator in TLR signaling [ncbi , more ], to study a novel link between GILZ and regulation of epithelial sodium transport through modulation of ERK signaling [ncbi , more ], to study the HSulf-1 and HSulf-2 [ncbi , more ], to study whether KGF provided these same protective effects to cultured human retinal pigmented epithelial (RPE) cells (ARPE-19) [ncbi , more ], to detect phospho-p42 MAPK in HT-29 cells treated with NMT1-1 siRNA or NMT2-4 siRNA [ncbi , more ], to probe the control elements of the CYP1A1 switching module in H4IIE hepatoma cells [ncbi , more ], to detect ERK2 and phospho-ERK2 in HEK cells subject to knockdown of either PDE4D or PDE4B [ncbi , more ], to study the changes of retinal gene expression in proliferative vitreoretinopathy [ncbi , more ], to investigate the regulatoin of Fbw7-mediated cyclin E proteolysis by Ras [ncbi , more ], to define the components in cyclic AMP-dependent UCP1 expression pathway in adipocytes [ncbi , more ], to study the inhibition of activator protein-1, NF-{kappa}B, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid [ncbi , more ], to study the association of PDGFRB and LRP [ncbi , more ], to study the relationship between FPR expression and the biologic behavior of glioma cells [ncbi , more ], to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ], to study the CDX1 as an important molecular mediator of Barrett's metaplasia [ncbi , more ], to study the Multifunctional Protein CAD which is phosphorylized by nuclear localization and mitogen-activated protein kinase [ncbi , more ], to study the inhibition of matrix metalloproteinase-9 expression by ascochlorin [ncbi , more ], to study the effect on BAD phosphorylation and Bcl-2 association by Raf-1 phosphorylation [ncbi , more ], to study the role of Ciliary neurotrophic factor (CNTF) to induce the dedifferenciation of adult human myoblasts via p44/p42 MAPK pathway in vitro [ncbi , more ], to demonstrate that Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L [ncbi , more ], to demonstrate that MAPK signaling pathway regulates GADD45beta expression during acute inflammation [ncbi , more ], to characterize heparin affin regulatory peptide signaling in human endothelial cells [ncbi , more ], to study the effect of enhanced p38 MAPK activity on endothelial cell function [ncbi , more ], to study the regulation of inducible cyclooxygenase-2 and prostaglandin E2 synthesis by Clostridium difficile toxin A via reactive oxygen species and activation of p38 MAPK [ncbi , more ], to study the inhibitory effects of galanin receptor 1 on proliferation in oral squamous cell carcinoma [ncbi , more ], to study the mitogenic activity of urokinase-type plasminogen activator which is determined by the dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex [ncbi , more ], to study the function of the mitogen-activated protein kinase kinase kinase DLK as a key regulator of keratinocyte terminal differentiation [ncbi , more ], to study the biological function of Rac-MKK3/6-p38 pathway [ncbi , more ], to study the effect of signal transducers and activators of transcription 3 on the transcriptional activity of CCAAT/enhancer-binding protein beta in granulocyte colony-stimulating factor signaling pathway [ncbi , more ], to study the central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptors [ncbi , more ], to study VEGF mRNA stability in DU145 prostate carcinoma [ncbi , more ], to study the role of macrophage surface phospholipases in GPI-induced innate immune responses and malaria pathogenesis [ncbi , more ], to study the biological function of estrogen receptors in the rapid effects of resveratrol and estradiol [ncbi , more ], to study cells with mutant IGF-I receptor at tyrosines 1250 and 1251 [ncbi , more ], to study glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression [ncbi , more ], to study the effects of hric3 on alpha7 receptors [ncbi , more ]and to study the effect of receptor-type protein-tyrosine phosphatase-kappa on epidermal growth factor receptor function [ncbi , more ]. Cell Signaling Technology ERK2 antibody was utilized in 2004 to study the role of KSR1 in regulating intestinal cell fate during cytokine-mediated inflammation [ncbi , more ], to evaluate therapeutic potential of the combination of IGFBP-3 and SCH66336 [ncbi , more ], to detect ERK and phosphorylated ERK in human HEK 293 cells [ncbi , more ], to study interleukin 7 effects on T cell acute lymphoblastic leukemia cells [ncbi , more ], to examine the levels of ERK1/ERK2 in human melanoma cell line A375 [ncbi , more ], to study the function of Gs-coupled receptors to induce activation of H-Ras and the ERK1/2 MAP kinases by an Epac- and Ca2+-controlled pathway [ncbi , more ], to study the role of Raf-1 activation during cell stress [ncbi , more ], to detect Erk2 and phospho-Erk2 in human coronary artery endothelial cells (HCAEC) treated with VEGF or HGF [ncbi , more ], to detect phospho-p42MAPK in NIH 3T3 cells transiently transfected with vector, RACK1, or mutant RACK1, and HEK 293 cells transfected with RACK1 siRNAs [ncbi , more ], to detect phospho-Erk2 in HeLa cells with FTI treatment [ncbi , more ], to study the role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis [ncbi , more ], to study the roles of the phosphatidylinositol (PI) 3-kinase and mitogen-activated protein (MAP) kinase-dependent pathways in the effect of mediating insulin on SREBP-1 in L-6 skeletal muscle cells and 3T3 L1 adipocytes [ncbi , more ], to study the overexpression of mitogen-activated protein kinase phosphatase-1 which is an independent predictor of outcome in patients in non-small cell lung cancer [ncbi , more ], to study the molecular mechanisms downstream of BTC involved in mediating vascular remodeling [ncbi , more ], to detect dually phosphorylated ERK in mouse 308 cells and human MCF10A cells [ncbi , more ], to determine if PDE4 is involved in MEK/ERK signaling-mediated memory [ncbi , more ], to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ], to detect phospho-ERK2 in human differentiated myotubes stimulated with insulin [ncbi , more ], to study the role of PPARgamma and EGFR signalling.

    Feedback from the author

    Clone/Cat no (supplier): #9101 (New Englanot done Biolabs); Host: rabbity (poly); western blot: we are happy with it; immunoprecipitation: not done; IF: we are happy with it; IHC: not done [ncbi , more ], to detect Akt and phospho-Akt in ET-1-treated lung fibroblasts from open lung biopsy specimens from SSc patients [ncbi , more ], to detect the presence of phosphorylated MAPK in porcine aortic endothelial (PAE) cells [ncbi , more ], to detect ERK2 and phospho-ERK2 in human ejaculate spermatozoa [ncbi , more ], to study the proangiogenic activity of AFP in the fetomaternal unit and its possible role during pregnancy in the present study [ncbi , more ], to demonstrate that MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts [ncbi , more ], to study the effect of Pyk2 on epidermal growth factor and c-Src-induced Stat3 activation in HeLa cell [ncbi , more ], to detect phospho-p42 ERK in NR6 WT cells and NR6 c'973 cells [ncbi , more ], to detect phospho-p42 MAPK in rat cardiac myocytes infected with recombinant adenoviruses containing human wild type or mutant cDNA of RasGAP, Akt or ILK [ncbi , more ], to detect phospho-ERK2 in 3T3-L1 cells infected with a retrovirus carrying the gene for C/EBPalpha [ncbi , more ], to study tumor necrosis factor-alpha signaling pathways [ncbi , more ], to study the role of CRHR2 in the control fo myometrial contractility [ncbi , more ], to study the function of RNase L and c-Jun NH2-terminal kinase in the interferon antiviral response [ncbi , more ], to study the role of adiponectin in angiogenesis [ncbi , more ]and to examined the Ser/Thr phosphorylation status of ERK in control HUVECs and HeLa cells [ncbi , more ]. Cell Signaling Technology ERK2 antibody was applied in 2003 to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells [ncbi , more ], to detect phosphorylated ERK in A549 cells infected with RSV [ncbi , more ], to detect p42 MAPK and phopho-p42 MAPK in SK-LMS-1 cells and MDA-MB-231 cells with human TSP1 transfection [ncbi , more ], to study the Initiation of CD38 signaling in T Cells within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor [ncbi , more ], to study the protective role of SCP and SRP against hypoxia/rexygenation injury in rat neonatal cardiomyocytes [ncbi , more ], to detect P42 MAPK and phospho-P42 MAPK in fibroblasts containing wild type Cas, CasY253F, or Cas118423 [ncbi , more ], to detect ERK2 and phospho-ERK2 in baculovirus infected with different versions of human Itk [ncbi , more ], to investigate the activation of ERK1/2 in primary human melanocytes isolated from neonatal foreskins and in the human melanoma SK-MEL-24 and SK-MEL-28 cell lines [ncbi , more ], to detect ERK2 and phospho-ERK2 in mutant and normal lymphocytes from patients [ncbi , more ], to study the interaction of Bcr kinase and AF-6 and the effects of them on Ras signaling [ncbi , more ], to study the expression, function, and signaling pathways of PCDGF in human MM [ncbi , more ], to determine whether differences in the activation of p38 by phosphorylation (p38-P) might contribute to the sex-dimorphic immune response following T-H [ncbi , more ], to identify two substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5 [ncbi , more ], to study the GIPC interaction with beta1-adrenergic receptor and its regulation on beta1-adrenergic receptor-mediated ERK activation [ncbi , more ], to study the role of Rit in human neuroblastoma cells for MEK-independent neurite branching [ncbi , more ], to study that resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells [ncbi , more ], to study the effect of ERK and p38 on 4E-BP1 expression [ncbi , more ], to study ras activation by acute hyperglycemia [ncbi , more ], to study the expression of hypertonicity-induced aquaporin-1 (AQP1) which is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene [ncbi , more ], to identify a putative G protein-coupled receptors (GPCR) as an intermediary in meiotic maturation of fish oocytes [ncbi , more ], to demonstrate that Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway [ncbi , more ], to study the role of EWS/FLI-1 in the alteration of mesodermal cell differentiation [ncbi , more ], to study the role for PI 3-kinase in HHV-8 entry into the target cells and the role for PKC-zeta, MEK, and ERK at a post-viral entry stage of infection [ncbi , more ], to study the regulation of activity of the human tissue factor pathway inhibitor-2 promoter by the ERK/MAPK pathway [ncbi , more ], to study the interaction between TAB1 isoform and p38alpha [ncbi , more ]and to detect the protein levels of phosphorylated Erk-2, and in flow cytometry to analyze for phospho-p44/42 MAP kinase (Thr204/Tyr204) in human Jurkat E6-1 T cells [ncbi , more ]. Cell Signaling Technology ERK2 antibody was applied in 2002 to study the role for Leptin in normal mammary gland development and in normal and malignant breast cells from human [ncbi , more ], to study the function of beta-arrestin2 as a mediator of stromal cell-derived factor 1alpha-induced chemotaxis via the ASK1/p38 MAPK pathway [ncbi , more ], to investigate the phosphorylation of ERK1/2 in human microvascular endothelial cells isolated by enzymatic digestion of blood vessels taken from the mesentery of the small bowel (designated MM1 cells) [ncbi , more ], to study the regulation and the functional consequences after the extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease [ncbi , more ], to study the role of p42/44 MAPK and protein kinase B in CTGF induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells [ncbi , more ], to study the significance of the dimerization function associated with the BTB/POZ domain of Keap1 for sequestration of Nrf2 in the cytoplasm [ncbi , more ], to study the coupling of human 5-HT1A, 5-HT1B, and 5-HT1D receptors to the MAP kinase ERK [ncbi , more ], to study the regulation of heterodimerization beta1/beta2-adrenergic receptor for beta2-adrenergic receptor internalization and ERK signaling efficacy [ncbi , more ], to examine the levels of activated ERK in A2780 and OVCAR5 ovarian cancer cell lines and human HEK293 cells [ncbi , more ], to study the regulation of the phosphorylation of MAP kinases by UVB [ncbi , more ], to further elucidate the activation mechanism for intracellular signaling mediated by interaction between Dok1 and phosphorylated RET [ncbi , more ], to investigate ERK activity in A549 human lung cancer cells [ncbi , more ], to study the regulatory role of protein kinase A anchoring protein (AKAP) related protein in the modulation of SPHK1 activity in human HEK 293 cells [ncbi , more ], to study stress-induced ATF6 phosphorylation [ncbi , more ], to study the ERK5 signaling pathway regulation by PTP-SL [ncbi , more ], to detect phosphorylated p42 MAPK in chlorate-treated Rama 27 fibroblasts [ncbi , more ], to study cell survival by GLP-2R signaling [ncbi , more ], to study a potential role for tyrosine phosphatases [ncbi , more ], to study the role for the interaction between RACK1 and insulin-like growth factor 1 (IGF-1) receptor in regulating IGF-1-mediated Akt activation and protection from cell death [ncbi , more ], to study the role of CD147 as a cell surface receptor for CyPA and an essential component in the CyPA-initiated signaling cascade that culminates in ERK activation [ncbi , more ], to detect Erk-2 in HUVEC [ncbi , more ], to study expression of p53, ErbB1, ErbB2, and Raf-1 in lung cancer [ncbi , more ], to detect phospho-ERK2 in D5 and vector HEK293 cells untreated or treated with insulin [ncbi , more ], to study the role of Ng in neural function using a strain of Ng knockout mouse [ncbi , more ], to study the role of RSK in signaling chemokine responses and synthesis in astrocytes [ncbi , more ], to detect phospho-ERK2 in A549 cells [ncbi , more ], to study the frequent co-Localization of cox-2 and laminin-5 2 chain at the invasive front of early-stage lung adenocarcinomas [ncbi , more ], to investigate a novel mechanism for the regulation of Rac activity and lamellipodia formation by RET tyrosine kinase [ncbi , more ], to study the role for Q227L-Galpha in inhibiting growth of established tumors of later-stage human breast cancer cells in athymic mice [ncbi , more ], to study the interactions between pharmacological MEK1/2 inhibitors and STI571 in Bcr/Abl-positive human leukemia cells [ncbi , more ], to study the role of KSR in the Raf/MEK/ERK kinase cascade [ncbi , more ]and to study IL-1 mediated MUC2 gene expression and mucin secretion in NCI-H292 cells via zctivation of PKC-MEK/ERK, and PI3K in human airway epithelial cells [ncbi , more ]. Cell Signaling Technology ERK2 antibody was employed in 2001 to study migration and signal transduction in corneal epithelial cells [ncbi , more ], to study the role of IG20 in TNF--induced apoptosis and activation of caspase-8 and 3 [ncbi , more ], to study the expression of activated ERK1/2 in head and neck squamous carcinoma and their relationship with EGF receptor/TGF-alpha expression [ncbi , more ], to study the role of PDEgamma in regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells [ncbi , more ], to study the novel mitogen-activated protein kinase phosphatase, MKP-7 [ncbi , more ], to study the regulation of Ca2+/Calmodulin-dependent eNOS activity by the phosphorylation of eNOS Thr495 [ncbi , more ], to identify a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-Cell receptor-mediated activation of PLC-1 and NFAT [ncbi , more ], to study the role of docking protein FRS2 in mitogen-activated protein kinase signaling cascade [ncbi , more ], to study the role of filamin-A in participating in CaR-mediated activation of mitogen-activated protein kinaseas by binding to the CaR's carboxyl-terminal tail [ncbi , more ], to investigate the inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade [ncbi , more ], to study the transcriptional program induced by Raf in epithelial cells [ncbi , more ], to study growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors [ncbi , more ], to study the effects of flavopiridol on PMA-induced differentiation and CDKI expression in human myeloid leukemia cells [ncbi , more ], to study the effect of SNT1 on ERK activation and neuronal differentiation in PC12 cells [ncbi , more ], to study the role of 7 nicotinic receptor in transduing signals to phosphatidylinositol 3-kinase to block a-amyloid-induced neurotoxicity [ncbi , more ], to Smad, ERK1/2, and p38 mitogen-activated protein kinase pathway cross-talka in chondrogenic ATDC5 cells [ncbi , more ], to study the mechanisms of Raf-1 activation [ncbi , more ], to study ERK2 nuclear shuttling in RBL-2H3 cells [ncbi , more ], to study Rho-ERK6 gene expression regulation pathway [ncbi , more ], to study the interactions between a purine analogue and kinase inhibitor UCN-01 in human leukemia and lymphoma cells [ncbi , more ], to study the role of CD45 in monocytic cells [ncbi , more ], to study a novel mechanism of cooperation between c-Kit and erythropoietin receptor [ncbi , more ]and to detect phospho-ERK2 in NIH-3T3 fibroblasts transfected with expression vector for GFP and C-terminal-truncated STAT3 [ncbi , more ].

Life Technologies CorporationLife Technologies Corporation ERK2 product
  • immunocytochemistryIn 2005, Guoyong Yin et al. utilized Life Technologies Corporation ERK2 antibody to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. In 2003, Sean R Conner et al. employed Life Technologies Corporation ERK2 antibody to detect the localization of activated ERK1/2 in human melanoma SK-MEL-28 cells [ncbi , more ].
  • western blotLife Technologies Corporation ERK2 antibody was used in 2005 to study the mitogenic activity of urokinase-type plasminogen activator which is determined by the dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex [ncbi , more ], to characterize lymphangiogenic vascular endothelial growth factors VEGF-C and D [ncbi , more ]and to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. Susana Castro-Obregon et al. employed Life Technologies Corporation ERK2 antibody to study SP/NK1R-induced cell death mediated by a MAP kinase activation pathway involving Raf-1, MEK2, and extracellular signal-regulated protein kinase 2 (ERK2) [ncbi , more ] in 2004 and Ana Maria Salicioni et al. used Life Technologies Corporation ERK2 antibody to study the role of LRP-1 in beta1 integrin maturation and transportation to the cell surface [ncbi , more ]. In 2001, D Yablonski et al. used Life Technologies Corporation ERK2 antibody to identify a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-Cell receptor-mediated activation of PLC-1 and NFAT [ncbi , more ].
Thermo Scientific Pierce ProductsThermo Scientific Pierce Products ERK2 product
  • western blotIn 2008, Francesco J Conti et al. applied Thermo Scientific Pierce Products ERK2 antibody to study the role of talin 1 in the development and function of skeletal muscle [ncbi , more ]. In 2004, Zhibo Yang et al. used Thermo Scientific Pierce Products ERK2 antibody to study estrogen receptor alpha modulation in breast cancer cells [ncbi , more ].
Active Motif
  • ELISAIn 2010, Weihua Li et al. used Active Motif ERK2 antibody to perform ELISA in order to study the role of HBx in regulation of c-Myc expression by activation of Ras/Raf/ERK1/2 cascades [ncbi , more ].
Novus Biologicals
  • western blotIn 2005, Ji-Youn Han et al. applied Novus Biologicals ERK2 antibody to study whether SCH66336 inhibits angiogenesis of aerodigestive tract cancer cells [ncbi , more ].
BD Biosciences
  • immunocytochemistryIn 2004, Zhibo Yang et al. used BD Biosciences ERK2 antibody to study estrogen receptor alpha modulation in breast cancer cells [ncbi , more ].
  • immunohistochemistryIn 2008, Xiu Yu Cui et al. employed BD Biosciences ERK2 antibody to study the role of mitogen-activated protein kinase (MAPK) in the generation of BV-induced pain hypersensitivity [ncbi , more ].
  • western blotLingyun Zhu et al. used BD Biosciences ERK2 antibody to examine the role of PGC-1alpha in vascular smooth muscle cell function [ncbi , more ] in 2009 and K J Feres et al. used BD Biosciences ERK2 antibody to perform western blot in order to study the oncogenic behavior of the RON receptor tyrosine kinase in breast epithelial cells [ncbi , more ]. In 2008, Sara Panigone et al. used BD Biosciences ERK2 antibody to study the role of luteinizing hormone signaling in the early activation of the EGF network [ncbi , more ]. BD Biosciences ERK2 antibody was applied in 2005 to study the convergence of cell cycle regulation and growth factor signals on GRASP65 [ncbi , more ], to characterize lymphangiogenic vascular endothelial growth factors VEGF-C and D [ncbi , more ]and to study SHPS-1 in the regulation of insulin-like growth factor I which stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells [ncbi , more ]. Zhibo Yang et al. used BD Biosciences ERK2 antibody to study estrogen receptor alpha modulation in breast cancer cells [ncbi , more ] in 2004 and Claire L Varley et al. used BD Biosciences ERK2 antibody to study the role of PPARgamma and EGFR signalling.

    Feedback from the author

    Clone/Cat no (supplier): clone 16 (BD transduction); Host: mouse; western blot: we are happy with it; immunoprecipitation: not done; IF: we are happy with it; IHC: not done [ncbi , more ]. Martin K Angele et al. utilized BD Biosciences ERK2 antibody to determine whether differences in the activation of p38 by phosphorylation (p38-P) might contribute to the sex-dimorphic immune response following T-H [ncbi , more ] in 2003 and Toru Furukawa et al. used BD Biosciences ERK2 antibody to identify DUSP6 as one of the key players in the tumor suppressive pathway and as a promising molecular target for curing patients with pancreatic cancer [ncbi , more ]. Christine Guntermann et al. employed BD Biosciences ERK2 antibody to study a potential role for tyrosine phosphatases [ncbi , more ] in 2002 and Veronique Bereziat et al. used BD Biosciences ERK2 antibody to study insulin receptor catalytic activity inhibition [ncbi , more ]. BD Biosciences ERK2 antibody was employed in 2001 to study the role of PDEgamma in regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells [ncbi , more ], to study the transcriptional program induced by Raf in epithelial cells [ncbi , more ]and to study the downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase [ncbi , more ].

  • immunocytochemistryIn 2005, Guoyong Yin et al. utilized Sigma-Aldrich ERK2 antibody to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. In 2004, Sunryeo Beom et al. employed Sigma-Aldrich ERK2 antibody to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ].
  • western blotIn 2009, Selwyn A Williams et al. used Sigma-Aldrich ERK2 antibody to demonstrate that fibulin-1 inhibits fibroblast spreading and cell-mediated contraction of a fibrin-FN matrix [ncbi , more ]. Sigma-Aldrich ERK2 antibody was used in 2008 to perform western blot in order to study the role of PICOT in FcepsilonRI-mediated mast cell activation [ncbi , more ], to show the activation of MAPK pathway caused by disulfide 1 in HCT116 cells [ncbi , more ]and to perform western blot in order to show that VHL tumor supppressor gene has endothelial function through fibroblast growth factor receptor signaling [ncbi , more ]. In 2006, Alessandra Spaziani et al. employed Sigma-Aldrich ERK2 antibody to detect ERK2 and activated-ERK2 in total cell extracts from HCV core-positive HepG2 cells transfected or not with siRNA core [ncbi , more ]. Sigma-Aldrich ERK2 antibody was utilized in 2005 to study galectin-8 signalling pathway [ncbi , more ], to study the inducing of platelet-derived growth factor C to liver fibrosis, steatosis, and hepatocellular carcinoma [ncbi , more ], to study the MMP-1 expression downregulation by Cdc42 inhibiting the ERK1/2 pathway [ncbi , more ], to study L1 expression in colon cancers [ncbi , more ], to study the biological function of 15 (S) hydroxyeicosatetraenoic acid in PKCaplpha translocation [ncbi , more ]and to investigate the role of GIT1 in ERK1/2 activation during focal adhesions [ncbi , more ]. Endre Kiss-Toth et al. applied Sigma-Aldrich ERK2 antibody to study the role of human tribbles protein family in controlling of mitogen-activated protein kinase cascades [ncbi , more ] in 2004 and Sunryeo Beom et al. used Sigma-Aldrich ERK2 antibody to study the molecular mechanism by which D2R and D3R activates ERK1/2 [ncbi , more ]. Gudiseva Chandrasekher et al. used Sigma-Aldrich ERK2 antibody to study the differential activation of phosphatidylinositol 3-kinase signaling during proliferation and differentiation of lens epithelial cells [ncbi , more ] in 2003 and Toru Furukawa et al. used Sigma-Aldrich ERK2 antibody to identify DUSP6 as one of the key players in the tumor suppressive pathway and as a promising molecular target for curing patients with pancreatic cancer [ncbi , more ]. Armelle Yart et al. applied Sigma-Aldrich ERK2 antibody to study the role of phosphoinositide 3-kinase beta lipid products in LPA-induced Ras activation [ncbi , more ] in 2002 and Haikun Shi et al. used Sigma-Aldrich ERK2 antibody to study the effect of ERK-mediated phosphorylation on the interactions of beta and gamma ENaC with Nedd4 [ncbi , more ].
NEW ENGLAND BIOLABORATORIES
  • western blotIn 2002, Thirupandiyur S Udayakumar et al. utilized ERK2 antibody to show that the fibroblast growth factor-1 induced promatrilysin expression [ncbi , more ].
Promega
  • western blotIn 2009, Angela J Sievert et al. applied Promega ERK2 antibody to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis [ncbi , more ]. Pablo Rodriguez-Viciana et al. applied Promega ERK2 antibody to study heterogeneous de novo missense mutations in three genes within the mitogen-activated protein kinase (MAPK) pathway [ncbi , more ] in 2006 and Anna Moshnikova et al. used Promega ERK2 antibody to detect ERK phosphorylation status in human A549 lung adenocarcinoma cells [ncbi , more ]. Promega ERK2 antibody was applied in 2005 to study ERK2 and p38 involvement in platelet adhesion to collagen [ncbi , more ], to study the convergence of cell cycle regulation and growth factor signals on GRASP65 [ncbi , more ], to study the role of PYK2 in the regulation SERCA2 gene expression in neonatal rat ventricular myocytes [ncbi , more ], to study COLO-357 cell growth inhibition by TGF beta1 [ncbi , more ], to study the inhibitory effects of galanin receptor 1 on proliferation in oral squamous cell carcinoma [ncbi , more ], to dissect the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol [ncbi , more ]and to study the induction of neuroblastoma cell apoptosis by TrkA [ncbi , more ]. Promega ERK2 antibody was employed in 2004 to detect phospho-extracellular signal-regulated kinase 2 in Panc-1 cells [ncbi , more ], to detect ERK2 in 3T3-L1 cells infected with a retrovirus carrying the gene for C/EBPalpha [ncbi , more ]and to detect total and phosphorylated p42/p44 MAPKs in primary human foreskin fibroblasts [ncbi , more ]. In 2003, Leng Wen et al. used Promega ERK2 antibody to study the effects of TL1A-induced NF- B and c-IAP2 on DR3-mediated apoptosis in TF-1 cells [ncbi , more ]. H Awata et al. utilized Promega ERK2 antibody to study the interaction between the CaR and filamin which is a potential scaffolding protein [ncbi , more ] in 2001 and C C Chen et al. used Promega ERK2 antibody to study the induction of adhesive signaling in primary human skin fibroblasts [ncbi , more ].
GE Healthcare Life Biosciences
  • western blotIn 2004, Andrew M F Liu et al. applied GE Healthcare Life Biosciences ERK2 antibody to detect ERK and phosphorylated ERK in human HEK 293 cells [ncbi , more ].
Figure
Cell Signaling anti-Erk and anti-p-Erk were used to perform western blot in order to show that thioredoxin is an IFN-gamma-induced factor and plays a role for cytokine production.
ERK2 antibody western blot Cell Signaling Technology
Analysis of Jak, Akt, and MAPK pathways during IFN-gamma signal transduction in THP1 cells. THP1 cells (1 x 106) were treated with media alone or IFN-gamma under serum-free conditions for the indicated times. The total cell lysates were then prepared and analyzed by Western blot to determine the activation status of Jak1/Stat1, Akt, and MAPKs as described in the text.
Seol Hee Kim et al. (2008). "Identification of human thioredoxin as a novel IFN-gamma-induced factor: mechanism of induction and its role in cytokine production".PMID 18983687
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