This is a review about Daxx, based on 16 published articles (read how Labome selects the articles), using Daxx antibody in all methods. It is aimed to help Labome visitors find the most suited Daxx antibody.
Daxx synonym: BING2; DAP6; EAP1; CENP-C binding protein; ETS1-associated protein 1; Fas-binding protein; death-associated protein 6; fas death domain-associated protein

Santa Cruz Biotechnology
rabbit polyclonal (M-112)
  • IC; human; fig 5
Santa Cruz Biotechnology Daxx antibody (Santa Cruz Biotechnology, sc-7152) was used in immunocytochemistry on human samples (fig 5). Mol Syst Biol (2015) ncbi
rabbit polyclonal (M-112)
  • WB; human; fig 1
  • IC; human; 1:200; fig 3
Santa Cruz Biotechnology Daxx antibody (Santa, sc-7152) was used in western blot on human samples (fig 1) and in immunocytochemistry on human samples at 1:200 (fig 3). J Cell Sci (2015) ncbi
goat polyclonal (C-20)
  • IC; human; fig 6c
Santa Cruz Biotechnology Daxx antibody (Santa, sc-7000) was used in immunocytochemistry on human samples (fig 6c). PLoS Pathog (2014) ncbi
rabbit polyclonal (M-112)
  • WB; mouse
Santa Cruz Biotechnology Daxx antibody (Santa Cruz Biotechnology, sc-7152) was used in western blot on mouse samples. Genome Res (2014) ncbi
goat polyclonal (S-20)
  • WB; mouse
Santa Cruz Biotechnology Daxx antibody (Santa Cruz Biotechnology, sc-7001) was used in western blot on mouse samples. Genome Res (2014) ncbi
rabbit polyclonal (M-112)
  • WB; human; 1:500
In order to study the effect of ASF1 depletion on the alternative lengthening of telomeres, Santa Cruz Biotechnology Daxx antibody (Santa, sc-7152) was used in western blot on human samples at 1:500. Nat Struct Mol Biol (2014) ncbi
rabbit polyclonal (M-112)
  • WB; human
  • IP; human
Santa Cruz Biotechnology anti-DAXX was used to perform western-blot and immunoprecipitation in order to demonstrate that DAXX functions as a histone chaperone involved in the replication-independent deposition of H3.3.Genes Dev (2010) ncbi
rabbit polyclonal (M-112)
  • WB; human
  • IC; human
Santa Cruz anti-Daxx antibody was used to perform Western blot and immunofluorescence in order to indicate that the two functions of herpes simplex virus 1 ICP0, the degradation of PML and the blocking of silencing by the CoREST/REST/HDAC complex, are interdependent.J Virol (2009) ncbi
not indicated
  • WB; human
Santa Cruz rabbit polyclonal hDaxx antibody was used in western blot in order to demonstrate that nuclear domain 10 components PML and hDaxx independently contribute to the silencing of human cytomegalovirus (HCMV) IE gene expression.J Virol (2008) ncbi
Epitomics
not indicated
  • WB; human
Epitomics rabbit monoclonal anti-DAXX antibody was used for western blot in order to show that vasoactive intestinal peptide can promote HCMV MIE gene expression in human NT2 cells.J Virol (2009) ncbi
not indicated
  • WB; human
Epitomics rabbit monoclonal hDaxx antibody was used in western blot in order to demonstrate that nuclear domain 10 components PML and hDaxx independently contribute to the silencing of human cytomegalovirus (HCMV) IE gene expression.J Virol (2008) ncbi
Bethyl
rabbit polyclonal
  • IC; human; fig 3
Bethyl Daxx antibody (Bethyl Labs, A301-353A) was used in immunocytochemistry on human samples (fig 3). J Neurooncol (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • WB; human
Sigma-Aldrich Daxx antibody (Sigma-Aldrich, D7810) was used in western blot on human samples. J Virol (2013) ncbi
rabbit polyclonal
  • IHC; human
Sigma-Aldrich anti-DAXX was used in 1:150 to perform immunohistochemistry and FISH in order to show that telomere alternation is associated with ATRX and DAXX dysfunction in tumor patients.Science (2011) ncbi
rabbit polyclonal
  • WB; human
  • IP; human
Sigma anti-Daxx antibody was used in westrn blot and immunoprecipitation to study the role of Daxx in quiescent HCMV infections in vitro in human foreskin fibroblast (HF), N-Tera2 (NT2), HEK 293, and U-2 OS cellsJ Virol (2007) ncbi
not indicated
  • WB; human
  • IP; human
  • ChIP; human
Sigma Daxx antibody was used in western blot, immunoprecipitation, and ChIP assay to study transcriptional repression of smad4J Biol Chem (2005) ncbi
Cell Signaling Technology
rabbit monoclonal (25C12)
  • WB; human
Cell Signaling Technology Daxx antibody (Cell Signaling, 25C12) was used in western blot on human samples. Genes Dev (2012) ncbi
BD Biosciences
not indicated
  • IC; human
BD Pharmingen anti-DAXX antibody was used to perform immunocytochemistry in order to study the regulation of Fas-induced apoptosis by SUMO-1Proc Natl Acad Sci U S A (2007) ncbi
Exbio
not indicated
  • WB; human
Exbio anti-DAXX was used to perform western blot in order to study the regulation of Fas-induced apoptosis by SUMO-1Proc Natl Acad Sci U S A (2007) ncbi
Articles Reviewed
  1. Benjamin A Diner et al. (2015). "The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA".PMID 25665578
  2. Mengfan Tang et al. (2015). "Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance".PMID 25416818
  3. Myriam Scherer et al. (2014). "Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions".PMID 25412268
  4. Kristina Ivanauskiene et al. (2014). "The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity".PMID 25049225
  5. Ahsan S Farooqi et al. (2014). "Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations".PMID 24792489
  6. Roderick J O'Sullivan et al. (2014). "Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1".PMID 24413054
  7. Mandy Glass et al. (2013). "Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection".PMID 23221561
  8. Kajan Ratnakumar et al. (2012). "ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression".PMID 22391447
  9. Christopher M Heaphy et al. (2011). "Altered telomeres in tumors with ATRX and DAXX mutations".PMID 21719641
  10. Pascal Drané et al. (2010). "The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3".PMID 20504901
  11. Jinxiang Yuan et al. (2009). "Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells".PMID 19369332
  12. Haidong Gu et al. (2009). "The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem".PMID 18945770
  13. Nina Tavalai et al. (2008). "Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection".PMID 17942542
  14. Ryan T Saffert et al. (2007). "Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro".PMID 17596307
  15. Ingmar Meinecke et al. (2007). "Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts".PMID 17360386
  16. Che Chang Chang et al. (2005). "Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4".PMID 15637079