This is a review about COX-2, based on 24 published articles (read how Labome selects the articles), using COX-2 antibody in all methods. It is aimed to help Labome visitors find the most suited COX-2 antibody.
COX-2 synonym: COII; MTCO2

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Enzo Life SciencesEnzo Life Sciences COX-2 product
  • western blotIn 2005, Nastiti Wijayanti et al. applied Enzo Life Sciences COX-2 antibody to study its activation by the NAD (P) H oxidase inhibitor 4- (2-aminoethyl) benzenesulfonyl fluoride [ncbi , more ].
Life Technologies CorporationLife Technologies Corporation COX-2 product
  • immunohistochemistryIn 2001, M Jaksch et al. utilized Life Technologies Corporation COX-2 antibody to study that cytochrome c oxidase deficiency due to mutations in SCO2 can berescued by copper in human myoblasts [ncbi , more ].
  • western blotIn 2006, Aditi Chatterjee et al. utilized Life Technologies Corporation COX-2 antibody to perform western blot in order to show that hogg1 mutation in mammalian mitochondria leads to cell death under oxidative stress [ncbi , more , fig ]. In 2005, Katharine M Hardy et al. applied Life Technologies Corporation COX-2 antibody to study extracellular trafficking of myocilin in human trabecular meshwork cells [ncbi , more ]. Life Technologies Corporation COX-2 antibody was applied in 2004 to study the function of Tim50 to regulate mitochondrial integrity and cell death as a component of the mitochondrial translocator [ncbi , more ], to detect cytochrome oxidase subunit II (CO II) was used as a control in human HEK293 cells [ncbi , more ]and to study apoptotic association of active caspase 8 with the mitochondrial membrane [ncbi , more ]. In 2003, Congxiao Zhang et al. applied Life Technologies Corporation COX-2 antibody to investigate the oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor [ncbi , more ]. In 2002, Yin Guo et al. employed Life Technologies Corporation COX-2 antibody to illuminate that caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria [ncbi , more ]. M Jaksch et al. utilized Life Technologies Corporation COX-2 antibody to study that cytochrome c oxidase deficiency due to mutations in SCO2 can berescued by copper in human myoblasts [ncbi , more ] in 2001 and R Sundararajan et al. used Life Technologies Corporation COX-2 antibody to detect COXII in heLa cells infected with mock, Ad5dl309, or Ad5dl337 and then untreated or treated with TNF/CHX [ncbi , more ].
Thermo Scientific Pierce ProductsThermo Scientific Pierce Products COX-2 product
  • immunocytochemistryIn 2011, Ronald A Merrill et al. used Thermo Scientific Pierce Products COX-2 antibody to perform immunohistochemistry in order to investigate the role of the PKA/AKAP1 complex in the maintenance of mitochondrial integrity and the protection from neuronal injury [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology COX-2 product
  • immunocytochemistryIn 2002, Daizo Korita et al. employed Santa Cruz Biotechnology COX-2 antibody to study prostacyclin production in cultured human uterine myometrial cells from pregnant women [ncbi , more ].
  • immunohistochemistryIn 2005, Vaneeta Marwaha et al. used Santa Cruz Biotechnology COX-2 antibody to investigate the decrease of COX-2 Levels through p53 and NFkB by T-oligo [ncbi , more ]. Christian Maihofner et al. applied Santa Cruz Biotechnology COX-2 antibody to study cyclooxygenase-2, interleukin-1beta, interleukin-6, and NF-kappaB expression in human colorectal cancer [ncbi , more ] in 2003 and Daisuke Kamei et al. used Santa Cruz Biotechnology COX-2 antibody to study the role of microsomal prostaglandin E synthase-1 in tumorigenesis [ncbi , more ].
  • western blotIn 2005, Vaneeta Marwaha et al. used Santa Cruz Biotechnology COX-2 antibody to investigate the decrease of COX-2 Levels through p53 and NFkB by T-oligo [ncbi , more ]. Christian Maihofner et al. applied Santa Cruz Biotechnology COX-2 antibody to study cyclooxygenase-2, interleukin-1beta, interleukin-6, and NF-kappaB expression in human colorectal cancer [ncbi , more ] in 2003 and Daisuke Kamei et al. used Santa Cruz Biotechnology COX-2 antibody to study the role of microsomal prostaglandin E synthase-1 in tumorigenesis [ncbi , more ]. In 2002, Daizo Korita et al. employed Santa Cruz Biotechnology COX-2 antibody to study prostacyclin production in cultured human uterine myometrial cells from pregnant women [ncbi , more ].
AbD Serotec
  • western blotIn 2002, Seijiro Taniura et al. used AbD Serotec COX-2 antibody to study the effect of histone deacetylase inhibitors on cyclooxygenase-1 in normal human astrocyte cells [ncbi , more ].
Immuno-Biological Laboratories
  • immunohistochemistryIn 2006, Takako Imada et al. used Immuno-Biological Laboratories COX-2 antibody to study the role for heparanase in COX-2 mediated tumor angiogenesis in breast-cancer progression in paraffin sections from human breast cancer [ncbi , more ].
S KARGMAN (MERCK FROSST)
  • immunohistochemistryIn 2007, Xinlei Chen et al. applied COX-2 antibody to study the early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptor [ncbi , more ].
MERCK FROSST CANADA
  • immunohistochemistryIn 2003, Eric T T L Tjwa et al. utilized COX-2 antibody to study activation of enteric neurons and enteric glia in the guinea pig ileum and colon by IL1B [ncbi , more ].
MOLECULAR PROBES INC
  • western blotIn 2002, Marion MacFarlane et al. employed COX-2 antibody to study the role of proteasome in degradation of Smac during apoptosis [ncbi , more ].
Cayman Chemical
  • immunohistochemistryIn 2007, Sandra Donnini et al. used Cayman Chemical COX-2 antibody to study the promotion of squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways by EP2 prostanoid receptor [ncbi , more ]. In 2005, Chang Han et al. employed Cayman Chemical COX-2 antibody to study the activation of EGFR and Akt by Cox2-derived prostaglandin E2 [ncbi , more ].
  • immunoprecipitationIn 2005, Chang Han et al. employed Cayman Chemical COX-2 antibody to study the activation of EGFR and Akt by Cox2-derived prostaglandin E2 [ncbi , more ].
  • western blotP C Lin et al. utilized Cayman Chemical COX-2 antibody to study luteinizing hormone/human chorionic gonadotropin receptor in human cervix [ncbi , more ] in 2003 and Wangsheng Yu et al. used Cayman Chemical COX-2 antibody to study the role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis [ncbi , more ].
Figure
Molecular Probes anti-Cox II was used to perform western blot in order to show that hogg1 mutation in mammalian mitochondria leads to cell death under oxidative stress.
COX-2 antibody western blot Life Technologies Corporation
HeLa cells were transfected with empty vector, MTS-hOGG1, MTS-mutant-hogg1.Mitochondrial, nuclear and total cellular extracts were isolated and analyzed by Western blot analysis using anti-OGG1 antiserum. Twenty microgram of mitochondrial, nuclear and total cellular extract for each indicated transfection was loaded into each lane
Aditi Chatterjee et al. (2006). "Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress".PMID 17018150
Articles Reviewed
  1. Ronald A Merrill et al. (2011). "Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1".PMID 21526220
  2. Xinlei Chen et al. (2007). "Early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptor".PMID 17603635
  3. Sandra Donnini et al. (2007). "EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways".PMID 17384145
  4. Aditi Chatterjee et al. (2006). "Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress".PMID 17018150
  5. Takako Imada et al. (2006). "COX-2 induction by heparanase in the progression of breast cancer".PMID 16391819
  6. Vaneeta Marwaha et al. (2005). "T-oligo treatment decreases constitutive and UVB-induced COX-2 levels through p53- and NFkappaB-dependent repression of the COX-2 promoter".PMID 16046401
  7. Katharine M Hardy et al. (2005). "Extracellular trafficking of myocilin in human trabecular meshwork cells".PMID 15944158
  8. Chang Han et al. (2005). "Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt".PMID 15855163
  9. Nastiti Wijayanti et al. (2005). "Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes".PMID 15833736
  10. Dhyan Chandra et al. (2004). "Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death".PMID 15254227
  11. Yin Guo et al. (2004). "Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death".PMID 15044455
  12. Ulrike Reiss et al. (2004). "Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis".PMID 14570870
  13. Eric T T L Tjwa et al. (2003). "Interleukin-1beta activates specific populations of enteric neurons and enteric glia in the guinea pig ileum and colon".PMID 12881225
  14. P C Lin et al. (2003). "Human cervix contains functional luteinizing hormone/human chorionic gonadotropin receptors".PMID 12843195
  15. Christian Maihofner et al. (2003). "Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer".PMID 12727794
  16. Congxiao Zhang et al. (2003). "Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor".PMID 12668724
  17. Daisuke Kamei et al. (2003). "Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis".PMID 12626523
  18. Wangsheng Yu et al. (2003). "Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis".PMID 12480928
  19. Daizo Korita et al. (2002). "Cyclic mechanical stretch augments prostacyclin production in cultured human uterine myometrial cells from pregnant women: possible involvement of up-regulation of prostacyclin synthase expression".PMID 12414894
  20. Marion MacFarlane et al. (2002). "Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro".PMID 12121969
  21. Seijiro Taniura et al. (2002). "Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells".PMID 11877441
  22. Yin Guo et al. (2002). "Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria".PMID 11832478
  23. M Jaksch et al. (2001). "Cytochrome c oxidase deficiency due to mutations in SCO2, encoding a mitochondrial copper-binding protein, is rescued by copper in human myoblasts".PMID 11751685
  24. R Sundararajan et al. (2001). "Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K".PMID 11571294