This is a review about COX-1, based on 20 published articles (read how Labome selects the articles), using COX-1 antibody in all methods. It is aimed to help Labome visitors find the most suited COX-1 antibody.
COX-1 synonym: COI; MTCO1

Abcam
mouse monoclonal (1D6E1A8)
  • WB; rat; 1:500
In order to test if mitochondrial energetics of large cerebral arteries are sex dependent, Abcam COX-1 antibody (Abcam, Ab14705) was used in western blot on rat samples at 1:500. Am J Physiol Heart Circ Physiol (2015) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human
In order to demonstrate that altered/impaired expression of mtDNA induces CHOP-10 expression dependent on the eIF2alpha/ATF4 axis of the integrated stress response, Abcam COX-1 antibody (Abcam, Ab14705) was used in western blot on human samples. Mitochondrion (2015) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human; 1:1000
In order to discuss the known phenotypes related to AIFM1 mutations and further study a single patient, Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on human samples at 1:1000. Mitochondrion (2015) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human
In order to present a case of a patient with isolated mitochondrial complex IV (cytochrome c oxidase) deficiency, Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on human samples. Eur J Hum Genet (2015) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human; 1:2000; fig s1
In order to describe mitochondrial biogenesis during hepatogenic differentiation of bone marrow-mesenchymal stem cells, Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on human samples at 1:2000 (fig s1). Int J Biochem Cell Biol (2014) ncbi
mouse monoclonal (1D6E1A8)
  • WB; rat; 1:1000
Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on rat samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (1D6E1A8)
  • IHC-P; human; 1:100
Abcam COX-1 antibody (Abcam, ab14705) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Neurosci Methods (2014) ncbi
mouse monoclonal (1D6E1A8)
  • WB; mouse
Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on mouse samples. FASEB J (2014) ncbi
rabbit polyclonal
  • IHC; human
Abcam COX-1 antibody (Abcam, ab45918) was used in immunohistochemistry on human samples. Kidney Int (2014) ncbi
mouse monoclonal (1D6E1A8)
  • IP; human; 1:1000
Abcam COX-1 antibody (Abcam, ab14705) was used in immunoprecipitation on human samples at 1:1000. Am J Hum Genet (2013) ncbi
mouse monoclonal (1D6E1A8)
  • IC; human
Abcam mouse anti-MTCO1 antibody was used to perform immunocytochemistry in order to investigate the functional property of the MCU gene.elife (2013) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human
Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on human samples. Neurobiol Dis (2013) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human
Abcam COX-1 antibody (Abcam, ab14705) was used in western blot on human samples. Cell Res (2013) ncbi
mouse monoclonal (1D6E1A8)
  • WB; human; 1:1000
Abcam COX-1 antibody (Abcam, AB14705) was used in western blot on human samples at 1:1000. Mitochondrion (2013) ncbi
mouse monoclonal (1D6E1A8)
  • IC; mouse; 1:100
  • WB; mouse
Abcam COX-1 antibody (Abcam, ab14705) was used in immunocytochemistry on mouse samples at 1:100 and in western blot on mouse samples. PLoS ONE (2012) ncbi
Santa Cruz Biotechnology
goat polyclonal (C-20)
  • WB; human; 1:100-400
  • WB; rat; 1:100-400
In order to investigate apelin signaling in brown adipocyte tissue, Santa Cruz Biotechnology COX-1 antibody (Santa Cruz Biotechnology, sc-23982) was used in western blot on human samples at 1:100-400 and on rat samples at 1:100-400. J Biol Chem (2015) ncbi
not indicated
  • IP; human
Santa Cruz Biotechnology goat polyclonal anti-COX-1 antibody was used in immunoprecipitation to study the expression of mRNA, protein, and catalytic activities of human cyclo-oxygenase-1 and an alternative splice variant.Biochem J (2005) ncbi
Invitrogen
not indicated
  • WB; human
Molecular Probes Cox I antibody was used in western blot to investigate the effect of mitochondrial stress on p21 expression and cell apoptosisJ Biol Chem (2005) ncbi
EMD Millipore
not indicated
  • IHC; human
Dr. S Kargman (Merck Frosst) COX-1 (1:500) antibody was used in immunohistochemistry (1:1000) to study the early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptorNeoplasia (2007) ncbi
Cayman Chemical
not indicated
  • WB; human
Cayman Chemical anti-COX-1 monoclonal antibody (1:300) was used in western blot in order to investigate the dysfunction of vascular smooth muscle in streptozotocin-induced diabetic ratsBr J Pharmacol (2008) ncbi
not indicated
  • WB; human
Cayman Chemical ovine monoclonal anti-COX-1 antibody was used in western blot to study the expression of mRNA, protein, and catalytic activities of human cyclo-oxygenase-1 and an alternative splice variant.Biochem J (2005) ncbi
Articles Reviewed
  1. Ibolya Rutkai et al. (2015). "Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries".PMID 26276815
  2. Aung Than et al. (2015). "Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes".PMID 25931124
  3. Sébastien Michel et al. (2015). "Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response".PMID 25643991
  4. Matthias Kettwig et al. (2015). "From ventriculomegaly to severe muscular atrophy: expansion of the clinical spectrum related to mutations in AIFM1".PMID 25583628
  5. Monika Oláhová et al. (2015). "A truncating PET100 variant causing fatal infantile lactic acidosis and isolated cytochrome c oxidase deficiency".PMID 25293719
  6. Anaïs Wanet et al. (2014). "Mitochondrial remodeling in hepatic differentiation and dedifferentiation".PMID 25084555
  7. Matthew W Rice et al. (2014). "Assessment of cytochrome C oxidase dysfunction in the substantia nigra/ventral tegmental area in schizophrenia".PMID 24941246
  8. Anne Grünewald et al. (2014). "Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue".PMID 24880043
  9. Marcin Buler et al. (2014). "SIRT5 is under the control of PGC-1α and AMPK and is involved in regulation of mitochondrial energy metabolism".PMID 24687991
  10. Pawaree Saisawat et al. (2014). "Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association".PMID 24152966
  11. Tobias B Haack et al. (2013). "ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy".PMID 23849775
  12. Dipayan Chaudhuri et al. (2013). "MCU encodes the pore conducting mitochondrial calcium currents".PMID 23755363
  13. Julia S Schlehe et al. (2013). "The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress".PMID 23702311
  14. Seungil Ro et al. (2013). "The mitochondrial genome encodes abundant small noncoding RNAs".PMID 23478297
  15. Nor Azian Abdul Murad et al. (2013). "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia".PMID 23178371
  16. Marcin Buler et al. (2012). "Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism".PMID 23166782
  17. Y Shi et al. (2008). "Oxidative stress and COX cause hyper-responsiveness in vascular smooth muscle of the femoral artery from diabetic rats".PMID 18414395
  18. Xinlei Chen et al. (2007). "Early alterations in ovarian surface epithelial cells and induction of ovarian epithelial tumors triggered by loss of FSH receptor".PMID 17603635
  19. Ching Hao Li et al. (2005). "Chloramphenicol-induced mitochondrial stress increases p21 expression and prevents cell apoptosis through a p21-dependent pathway".PMID 15905168
  20. Claus Schneider et al. (2005). "Human cyclo-oxygenase-1 and an alternative splice variant: contrasts in expression of mRNA, protein and catalytic activities".PMID 15361066