This is a review about BMI1, based on 26 published articles (read how Labome selects the articles), using BMI1 antibody in all methods. It is aimed to help Labome visitors find the most suited BMI1 antibody.
BMI1 synonym: FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1; B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; murine leukemia viral (bmi-1) oncogene homolog; polycomb group RING finger protein 4; polycomb group protein Bmi1; ring finger protein 51

Abcam
mouse monoclonal (1.T.21)
  • WB; human; 1:1000
Abcam BMI1 antibody (Abcam, ab14389) was used in western blot on human samples at 1:1000. Carcinogenesis (2015) ncbi
mouse monoclonal (1.T.21)
  • ChIP; human; fig 3f
Abcam BMI1 antibody (Abcam, ab14389) was used in chromatin immunoprecipitation on human samples (fig 3f). Nature (2014) ncbi
mouse monoclonal (1.T.21)
  • ChIP-Seq; human
  • ChIP; human
Abcam BMI1 antibody (Abcam, ab14389) was used in ChIP-Seq on human samples and in chromatin immunoprecipitation on human samples. J Biol Chem (2015) ncbi
mouse monoclonal (1.T.21)
  • IHC-P; human
Abcam BMI1 antibody (Abcam, ab14389) was used in immunohistochemistry - paraffin section on human samples. PLoS ONE (2014) ncbi
mouse monoclonal (1.T.21)
  • ChIP; human
Abcam BMI1 antibody (Abcam, ab14389) was used in chromatin immunoprecipitation on human samples. J Cell Mol Med (2014) ncbi
mouse monoclonal (1.T.21)
  • IHC-P; human; 1:100
Abcam BMI1 antibody (Abcam, ab14389) was used in immunohistochemistry - paraffin section on human samples at 1:100. Cancer Med (2014) ncbi
mouse monoclonal (1.T.21)
  • WB; human; 1:1000
Abcam BMI1 antibody (Abcam, ab14389) was used in western blot on human samples at 1:1000. PLoS ONE (2013) ncbi
rabbit monoclonal (EPR3745(2))
  • FC; human
Abcam BMI1 antibody (Abcam, ab126783) was used in flow cytometry on human samples. Cell Death Dis (2013) ncbi
mouse monoclonal (1.T.21)
  • IC; human
Abcam BMI1 antibody (Abcam, ab14389) was used in immunocytochemistry on human samples. EMBO J (2013) ncbi
R and D Systems
mouse monoclonal (384515)
  • WB; human
R and D Systems BMI1 antibody (R&D Systems, MAB33341) was used in western blot on human samples. J Cell Mol Med (2014) ncbi
mouse monoclonal (384515)
  • FC; human; 5 ul
R and D Systems BMI1 antibody (R&D Systems, IC33341F) was used in flow cytometry on human samples at 5 ul. Cancer Med (2014) ncbi
EMD Millipore
mouse monoclonal
  • ChIP; human
EMD Millipore BMI1 antibody (Millipore, 17-664) was used in chromatin immunoprecipitation on human samples. Nucleic Acids Res (2014) ncbi
mouse monoclonal (AF27)
  • WB; human
EMD Millipore BMI1 antibody (Millipore, 05-1321) was used in western blot on human samples. J Biol Chem (2013) ncbi
not indicated
  • WB; human
Upstate Biotechnology anti-Bmi-1 antibody was used to perform western blot in order to study the role of LMP2A in the nasopharyngeal carcinoma progression.PLoS Pathog (2010) ncbi
not indicated
  • WB; human
  • IC; human
  • ChIP; human
Upstate anti-Bmi1 antibody was used in western blot, immunocytochemistry, and ChIP assay to study the effect of expression of the SYT-SSX2 oncogene on polycomb function in human U2OS osteosarcoma cell line.PLoS ONE (2009) ncbi
not indicated
  • WB; human
  • IHC; human
Upstate Biotechnology rabbit polyclonal anti-Bmi-1 antibody and mouse monoclonal anti-Bmi-1 antibody were used in western blot and immunohistochemistry to analyze the expression of Bmi-1 protein and its clinical significance in human bladder cancer.BMC Cancer (2009) ncbi
not indicated
  • WB; human
  • IC; human
  • ChIP; human
Upstate mouse anti-BMI1 antibody was used in western blot, immunocytochemistry, and ChIP assay to demonstrate that CBX8 is part of one of the PRC1 complexes and regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.EMBO J (2007) ncbi
not indicated
  • WB; human
Upstate Cell Signaling Solutions F6 mouse monoclonal Bmi-1 antibody was used in western blot on to study the regulation of cell proliferation and senescence by Mel-18 via transcriptional repression of Bmi-1 and c-Myc oncoproteinsMol Biol Cell (2007) ncbi
not indicated
  • WB; human
Upstate Biotechnology anti-BMI1 antibody was used in western blot to study the role of PRC1 complex and CULLIN3/SPOP ligase complex in X inactivation.Proc Natl Acad Sci U S A (2005) ncbi
GeneTex
rabbit polyclonal
  • WB; human
GeneTex BMI1 antibody (GeneTex, GTX114008) was used in western blot on human samples. Cell Death Dis (2015) ncbi
Santa Cruz Biotechnology
rabbit polyclonal (H-99)
  • WB; human
In order to study the molecular basis for cisplatin chemoresistance in oral tongue squamous cell carcinoma, Santa Cruz Biotechnology BMI1 antibody (Santa Cruz Biotechnology, sc-10745) was used in western blot on human samples. PLoS ONE (2015) ncbi
Invitrogen
not indicated
  • WB; human
Zymed mouse monoclonal Bmi-1 antibody 1H6B10G7 was used in western blot on to study the regulation of cell proliferation and senescence by Mel-18 via transcriptional repression of Bmi-1 and c-Myc oncoproteinsMol Biol Cell (2007) ncbi
Bethyl
rabbit polyclonal
  • WB; human; fig 3a
Bethyl BMI1 antibody (Bethyl, A301-694A) was used in western blot on human samples (fig 3a). Nature (2014) ncbi
rabbit polyclonal
  • ChIP; human; fig 4e
  • IP; human; fig 4b
Bethyl BMI1 antibody (Bethyl, A301-694A) was used in chromatin immunoprecipitation on human samples (fig 4e) and in immunoprecipitation on human samples (fig 4b). elife (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (D20B7)
  • WB; human
Cell Signaling Technology BMI1 antibody (Cell signaling, D20B7) was used in western blot on human samples. Biochem Biophys Res Commun (2015) ncbi
not indicated
  • ChIP; human
Cell Signalling anti-aBmi1 antiboby was used to perform ChIP in order to study mitosis facilitate somatic cell nuclear reprogramming. PLoS Biol (2014) ncbi
rabbit monoclonal (D20B7)
  • ChIP; human; 1:100
  • IP; human; 1:1000
  • WB; human; 1:1000
In order to study the Involvement of EED in the organization of polycomb group complexes, Cell Signaling Technology BMI1 antibody (Cell Signaling, 6964) was used in chromatin immunoprecipitation on human samples at 1:100, in immunoprecipitation on human samples at 1:1000, and in western blot on human samples at 1:1000. Nat Commun (2014) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology BMI1 antibody (Cell Signaling Technology, 2830) was used in western blot on human samples. Oncol Rep (2013) ncbi
BD Biosciences
mouse monoclonal (P51-311)
  • FC; human
In order to correlate the expression of CD200 in various types of cancer with the responses to chemotherapy and radiation, BD Biosciences BMI1 antibody (BD Bioscience, 562528) was used in flow cytometry on human samples. Head Neck (2015) ncbi
Individual Researcher
not indicated
  • WB; human
  • ChIP; human
Dr. Kristian Helin (University of Copenhagen) mouse monoclonal BMI1 antibodies against full-length human BMI1 fused to the maltose-binding protein were used in western blot (Clone DC9) and in ChIP assay (Clone AF27) to study the binding of polycomb group proteins throughout the INK4A-ARF locus and their disassociation in senescent cellsGenes Dev (2007) ncbi
Articles Reviewed
  1. S Y Ju et al. (2015). "Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells".PMID 26136074
  2. Gautam Adhikary et al. (2015). "Survival of skin cancer stem cells requires the Ezh2 polycomb group protein".PMID 25969142
  3. Yueying Zhou et al. (2015). "Bmi1 essentially mediates podocalyxin-enhanced Cisplatin chemoresistance in oral tongue squamous cell carcinoma".PMID 25915207
  4. Kazuhiro Murata et al. (2015). "Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis".PMID 25660450
  5. Sanchita Bhatnagar et al. (2014). "TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein".PMID 25470042
  6. Neal A Englert et al. (2015). "Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9".PMID 25391650
  7. Anne Benard et al. (2014). "Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer".PMID 25243792
  8. Richard P Halley-Stott et al. (2014). "Mitosis gives a brief window of opportunity for a change in gene transcription".PMID 25072650
  9. Roberto Bonasio et al. (2014). "Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes".PMID 24986859
  10. Yuh Seog Jung et al. (2015). "CD200: association with cancer stem cell features and response to chemoradiation in head and neck squamous cell carcinoma".PMID 24700450
  11. Hongjie Shen et al. (2014). "BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression".PMID 24571310
  12. Qi Cao et al. (2014). "The central role of EED in the orchestration of polycomb group complexes".PMID 24457600
  13. Andrew J Dalley et al. (2014). "Expression of ABCG2 and Bmi-1 in oral potentially malignant lesions and oral squamous cell carcinoma".PMID 24415717
  14. Gautam Adhikary et al. (2013). "Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation".PMID 24376802
  15. Arindam Basu et al. (2014). "YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment".PMID 24285299
  16. Hsan Au Wu et al. (2013). "Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7".PMID 24194518
  17. H Liu et al. (2013). "Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells".PMID 24136221
  18. Yu Syuan Chen et al. (2013). "Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model".PMID 24100418
  19. Nadine Martin et al. (2013). "Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation".PMID 23455154
  20. Qing Li Kong et al. (2010). "Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma".PMID 20532215
  21. Roy Barco et al. (2009). "The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1".PMID 19337376
  22. Zi Ke Qin et al. (2009). "Expression of Bmi-1 is a prognostic marker in bladder cancer".PMID 19228380
  23. Adrian P Bracken et al. (2007). "The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells".PMID 17344414
  24. Nikolaj Dietrich et al. (2007). "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus".PMID 17332741
  25. Wei jian Guo et al. (2007). "Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins".PMID 17151361
  26. Inmaculada Hernández-Muñoz et al. (2005). "Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase".PMID 15897469