This is a review about B-Raf, based on 21 published articles (read how Labome selects the articles), using B-Raf antibody in all methods. It is aimed to help Labome visitors find the most suited B-Raf antibody.
B-Raf synonym: B-RAF1; BRAF1; NS7; RAFB1; 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); murine sarcoma viral (v-raf) oncogene homolog B1; proto-oncogene B-Raf; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1

Santa Cruz Biotechnology
rabbit polyclonal (H-145)
  • WB; mouse; fig s4e
Santa Cruz Biotechnology B-Raf antibody (Santa, sc-9002) was used in western blot on mouse samples (fig s4e). Nature (2015) ncbi
mouse monoclonal (F-7)
  • WB; human; fig 1
Santa Cruz Biotechnology B-Raf antibody (santa cruz, sc-5284) was used in western blot on human samples (fig 1). Carcinogenesis (2015) ncbi
rabbit polyclonal (C-19)
  • WB; mouse; 1:500
In order to assess if BRAF-KD is sufficient to induce gliomas or if Ink4a/Arf loss is also needed, Santa Cruz Biotechnology B-Raf antibody (Santa Cruz Biotechnology, SC166) was used in western blot on mouse samples at 1:500. Genes Cancer (2015) ncbi
mouse monoclonal (F-3)
  • WB; mouse; 1:200; fig 2
In order to investigate how BRAF/MAPK activity regulates intestinal stem cell populations and contributes to colon cancer, Santa Cruz Biotechnology B-Raf antibody (Santa Cruz, 55522) was used in western blot on mouse samples at 1:200 (fig 2). Oncogene (2015) ncbi
mouse monoclonal (F-7)
  • WB; human
Santa Cruz Biotechnology B-Raf antibody (Santa Cruz Biotechnology, sc-5284) was used in western blot on human samples. Cancer Res (2014) ncbi
rabbit polyclonal (C-19)
  • WB; human
Santa Cruz Biotechnology B-Raf antibody (Santa Cruz, sc-166) was used in western blot on human samples. Pigment Cell Melanoma Res (2014) ncbi
mouse monoclonal (F-7)
  • WB; hamsters
Santa Cruz Biotechnology B-Raf antibody (Santa Cruz Biotechnology, sc-5284) was used in western blot on hamsters samples. Mol Cell Biol (2013) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-Braf antibody was used to perform western blot in order to study the role of Raf-1 in glioma formation.Neoplasia (2008) ncbi
Spring Bioscience Corp.
mouse monoclonal (VE1)
  • IHC-P; human; 1:50
Spring Bioscience Corp. B-Raf antibody (Spring Bioscience, clone VE1) was used in immunohistochemistry - paraffin section on human samples at 1:50. Histopathology (2016) ncbi
mouse monoclonal (VE1)
  • WB; mouse; 1:2000
In order to assess if BRAF-KD is sufficient to induce gliomas or if Ink4a/Arf loss is also needed, Spring Bioscience Corp. B-Raf antibody (Spring Bioscience, E1929) was used in western blot on mouse samples at 1:2000. Genes Cancer (2015) ncbi
mouse monoclonal (VE1)
  • IHC; human; 1:50
Spring Bioscience Corp. B-Raf antibody (Spring Bioscience, VE1) was used in immunohistochemistry on human samples at 1:50. Pathol Res Pract (2014) ncbi
Abcam
not indicated
  • WB; human
Abcam anti-BRAF antibody was used to perform western blot in order to study the novel BRAF fusion gene in 7q34 duplication of pediatric low-grade astrocytomas detected by high density SNP-based genotype array analysis.Brain Pathol (2009) ncbi
Cell Signaling Technology
rabbit polyclonal
  • WB; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology B-Raf antibody (Cell Signaling, 9431) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal
  • WB; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology B-Raf antibody (Cell Signaling, 9421) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology B-Raf antibody (CST, 9421) was used in western blot on human samples. Cell Signal (2015) ncbi
rabbit monoclonal (55C6)
  • WB; human; 1:1000
In order to test if NBDHEX and MC3181 have antitumor activity against melanoma cells resistant to vemurafenib, Cell Signaling Technology B-Raf antibody (Cell Signaling Technology, 9433) was used in western blot on human samples at 1:1000. Biochem Pharmacol (2015) ncbi
rabbit monoclonal (56A6)
  • WB; human
Cell Signaling Technology B-Raf antibody (Cell Signaling Technology, 9427) was used in western blot on human samples. Int J Oncol (2015) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology B-Raf antibody (Cell Signaling, # 2696) was used in western blot on human samples. Oncotarget (2015) ncbi
rabbit monoclonal (56A6)
  • WB; hamsters
Cell Signaling Technology B-Raf antibody (Cell Signaling technology, 9427) was used in western blot on hamsters samples. Med Microbiol Immunol (2014) ncbi
rabbit monoclonal (56A6)
  • WB; human
Cell Signaling Technology B-Raf antibody (Cell Signalling, 9427) was used in western blot on human samples. Cell Microbiol (2014) ncbi
rabbit monoclonal (56A6)
  • WB; human
In order to study the ERbB signaling network with a view to understanding the basis for context-specific signaling plasticity, Cell Signaling Technology B-Raf antibody (Cell Signaling, 9427) was used in western blot on human samples. Sci Signal (2013) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology B-Raf antibody (Cell Signaling, 9421) was used in western blot on human samples. J Biol Chem (2013) ncbi
rabbit monoclonal (56A6)
  • WB; human
Cell Signaling Technology B-Raf antibody (Cell Signaling, 9427) was used in western blot on human samples. Cancer Cell Int (2013) ncbi
Articles Reviewed
  1. Vijay K Ulaganathan et al. (2015). "Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site".PMID 26675719
  2. Christelle Lenain et al. (2015). "Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence".PMID 26354777
  3. Rodica P Bunaciu et al. (2015). "6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells".PMID 26287494
  4. Shi Yun Chen et al. (2016). "Glioneuronal tumours with features of rosette-forming glioneuronal tumours of the fourth ventricle and dysembryoplastic neuroepithelial tumours: a report of three cases".PMID 26040650
  5. Xun Tang et al. (2015). "CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells".PMID 26004137
  6. Clifford H Shin et al. (2015). "The BRAF kinase domain promotes the development of gliomas in vivo".PMID 25821557
  7. Grazia Graziani et al. (2015). "A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib".PMID 25795251
  8. Yifei Wang et al. (2015). "The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells".PMID 25776829
  9. Consalvo Petti et al. (2015). "Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells".PMID 25473895
  10. P Riemer et al. (2015). "Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity".PMID 25109331
  11. Curtis H Kugel et al. (2014). "Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor".PMID 25035390
  12. Naoki Oishi et al. (2014). "Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: case report and literature review".PMID 24893893
  13. Ge Meng et al. (2014). "Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss".PMID 24870058
  14. Tyson P Eucker et al. (2014). "The focal complex of epithelial cells provides a signalling platform for interleukin-8 induction in response to bacterial pathogens".PMID 24779413
  15. Christina Kiel et al. (2013). "Integration of protein abundance and structure data reveals competition in the ErbB signaling network".PMID 24345680
  16. Jaehyuk Choi et al. (2014). "Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors".PMID 24283590
  17. Yanping Li et al. (2013). "Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation".PMID 23893412
  18. Shibo Lin et al. (2013). "MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma".PMID 23320839
  19. Dharini van der Hoeven et al. (2013). "Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission".PMID 23129805
  20. Angela J Sievert et al. (2009). "Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene".PMID 19016743
  21. Yelena Lyustikman et al. (2008). "Constitutive activation of Raf-1 induces glioma formation in mice".PMID 18472967