This is a review about ATM, based on 38 published articles (read how Labome selects the articles), using ATM antibody in all methods. It is aimed to help Labome visitors find the most suited ATM antibody.
ATM synonym: AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1; A-T mutated; AT mutated; TEL1, telomere maintenance 1, homolog; serine-protein kinase ATM

GeneTexGeneTex ATM product
  • immunocytochemistryIn 2005, Norvin Fernandes et al. applied GeneTex ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ]. In 2004, Joshua Silverman et al. used GeneTex ATM antibody to study the regulation of human Rif1, ortholog of a yeast telomeric protein by ATM and 53BP1 and functions in the S-phase checkpoint [ncbi , more ].
  • immunoprecipitationIn 2005, Norvin Fernandes et al. applied GeneTex ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ].
  • western blotIn 2010, Zhi Guo et al. used GeneTex ATM antibody to perform western blot in order to study the activation of ATM under conditions of oxidative stress (catalog: GTX70103) [ncbi , more ]. In 2009, Jennifer Hein et al. employed GeneTex ATM antibody to study the effect of simian virus 40 large T antigen on genome integrity and DNA damage response [ncbi , more ]. GeneTex ATM antibody was applied in 2005 to study DNA Damage-induced ATM association with its target proteins [ncbi , more ], to study the effect of Epstein-Barr virus lytic replication on ATM checkpoint signal transduction [ncbi , more ]and to identify ATM domains for nuclear localization and chromatin association [ncbi , more ]. Heather Beamish et al. employed GeneTex ATM antibody to to determine the protein expression patterns of EpCAM in renal cell carcinoma (RCC) [ncbi , more ] in 2002 and Shaun P Scott et al. used GeneTex ATM antibody to detect the dominant interfering effect of missense mutations in regions of the ATM protein on the activation of normal ATM kinase in patients with breast cancer [ncbi , more ].
Cell Signaling TechnologyCell Signaling Technology ATM product
  • immunocytochemistryIn 2011, Aniek Janssen et al. utilized Cell Signaling Technology ATM antibody to perform immunocytochemistry in order to show that chromosomal structural aberrations could be caused by chromosome segregation errors [ncbi , more ]. Noriko Shirata et al. applied Cell Signaling Technology ATM antibody to investigate the induction of DNA damage checkpoint signal transduction by herpes simplex virus [ncbi , more ] in 2005 and Ayumi Kudoh et al. used Cell Signaling Technology ATM antibody to study the effect of Epstein-Barr virus lytic replication on ATM checkpoint signal transduction [ncbi , more ]. In 2003, Zhenkun Lou et al. used Cell Signaling Technology ATM antibody to study the regulation of BRCA1 localization and phosphorylation in DNA damage checkpoint control by the mediator of DNA damage checkpoint protein 1 [ncbi , more ].
  • immunohistochemistryIn 2008, Suchismita Panda et al. employed Cell Signaling Technology ATM antibody to show in vivo accumulation of cells without extremes in enrichment or modification of many of the DDR proteins related to senescence

    Feedback from the author: ATM ANTIBODY WAS FOR PHOSPHOYLRATEDTARGET SEQUENCE FOR ATM KINASE. -CELL SIGNALLING [ncbi , more ].

  • western blotIn 2009, Stéphanie Solier et al. used Cell Signaling Technology ATM antibody to study the role of TRAIL for activation of DNA damage response pathways with histone H2AX and Chk2 phosphorylations [ncbi , more ]. Cell Signaling Technology ATM antibody was applied in 2005 to study the benzo[a]pyrene-dihydrodiol epoxide (BPDE) induced S-phase checkpoint [ncbi , more ], to study the effect of Epstein-Barr virus lytic replication on ATM checkpoint signal transduction [ncbi , more ]and to investigate the induction of DNA damage checkpoint signal transduction by herpes simplex virus [ncbi , more ].
EMD MilliporeEMD Millipore ATM product
  • immunocytochemistryIn 2009, Bettina Gruhne et al. employed EMD Millipore ATM antibody to carry out immunofluorescence assays in order to investigate the role of EBNA-1 in inducing chromosomal aberrations by production of reactive oxygen species [ncbi , more ]. EMD Millipore ATM antibody was employed in 2008 to show the synergistic cytotoxicity of VPA and cisplatin in ovarian cancer cells [ncbi , more ], to perform immunocytochemistry in order to show that in A549 cells the molecular machinery such as the recruitment of Mre11 and phosphorylation of ATM, Chk2, and H2AX (gammaH2AX) induced under oxidative stress [ncbi , more ]and to identify ataxia-telangiectasia mutated (ATM) as a further component of the complex signalling network of radiation-induced DNA damage in non-targeted bystander cells downstream of ataxia-telangiectasia and Rad3-related (ATR) [ncbi , more ]. Rekha Rai et al. employed EMD Millipore ATM antibody to perform immunocytochemistry in order to show that BRIT1 can regulate DNA damage as a tumor suppressor [ncbi , more ] in 2006 and Xuan Huang et al. used EMD Millipore ATM antibody to reveal the status of histone H3 and H2AX phosphorylation on Ser-10 and Ser-139 as well as ATM activation through phosphorylation on Ser-1981 during PCC [ncbi , more ].
  • immunoprecipitationIn 2005, Norvin Fernandes et al. applied EMD Millipore ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ].
  • western blotWen Hsing Cheng et al. utilized EMD Millipore ATM antibody to carry out western blot analysis in order to investigate the role for WRN in ATM pathway activation and the S-phase checkpoint in cells exposed to DNA interstrand cross-link-induced double-strand breaks [ncbi , more ] in 2008 and Jean Luc Perfettini et al. used EMD Millipore ATM antibody to demonstrate that ATM undergoes an activating phosphorylation in syncytia elicited by the envelope glycoprotein complex (Env) of human immunodeficiency virus-1 (HIV-1) in vitro [ncbi , more ]. In 2005, Norvin Fernandes et al. applied EMD Millipore ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ]. In 2001, S A Lee et al. applied EMD Millipore ATM antibody to study oxidative stress-mediated c-Jun phosphorylation [ncbi , more ].
Novus BiologicalsNovus Biologicals ATM product
  • immunocytochemistryIn 2006, Rekha Rai et al. employed Novus Biologicals ATM antibody to perform immunocytochemistry in order to show that BRIT1 can regulate DNA damage as a tumor suppressor [ncbi , more ]. In 2003, Zhi Xiang Xu et al. applied Novus Biologicals ATM antibody to detect the localization of ATM in human SiHa cells [ncbi , more ].
Santa Cruz BiotechnologySanta Cruz Biotechnology ATM product
  • immunohistochemistryIn 2009, Julia Leemput et al. applied Santa Cruz Biotechnology ATM antibody to incubate with the sections in order to determine the ATM expression patterns and studied its localization [ncbi , more ].
  • western blotIn 2008, Lei Li et al. used Santa Cruz Biotechnology ATM antibody to study the role for DEAD Box 1 in the repair of transcriptionally active regions of the genome [ncbi , more ]. In 2005, Wei Zhang et al. utilized Santa Cruz Biotechnology ATM antibody to detect ATM in GFP-centrin HeLa cells treated with caffeine, siRNA against ATM, Chk1 or Chk2 [ncbi , more ].
R and D SystemsR and D Systems ATM product
  • western blotIn 2010, Zhi Guo et al. employed R and D Systems ATM antibody to perform western blot in order to study the activation of ATM under conditions of oxidative stress [ncbi , more ].
Rockland Immunochemicals, Inc.Rockland Immunochemicals, Inc. ATM product
  • immunocytochemistryIn 2009, Rachel A Schwartz et al. applied Rockland Immunochemicals, Inc. ATM antibody to carry out immunofluorescence assays in order to investigate the effect of adeno-associated virus and adenovirus coinfection on inducing cellular DNA damage response [ncbi , more ]. In 2008, Lei Li et al. used Rockland Immunochemicals, Inc. ATM antibody to study the role for DEAD Box 1 in the repair of transcriptionally active regions of the genome [ncbi , more ]. David B Young et al. utilized Rockland Immunochemicals, Inc. ATM antibody to identify the ATM domains for nuclear localization and chromatin association [ncbi , more ] in 2005 and Norvin Fernandes et al. used Rockland Immunochemicals, Inc. ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ].
  • immunohistochemistryIn 2010, Jay P Reddy et al. applied Rockland Immunochemicals, Inc. ATM antibody to show the importance of protection of the ATM-mediated DDR-p53 signaling pathway for breast cancer prevention [ncbi , more ]. In 2008, Masahiro Nakashima et al. utilized Rockland Immunochemicals, Inc. ATM antibody to perform immunohistochemistry in order to study 53BP1 foci formation in thyroid carcinogenesis [ncbi , more ].
  • immunoprecipitationIn 2005, Norvin Fernandes et al. applied Rockland Immunochemicals, Inc. ATM antibody to study DNA Damage-induced ATM association with its target proteins [ncbi , more ].
  • western blotIn 2009, Yong Chul Kim et al. utilized Rockland Immunochemicals, Inc. ATM antibody to determine the effect of HMGN1 on ATM activation by regulating the levels of histone modifications [ncbi , more ]. Ali Jazayeri et al. used Rockland Immunochemicals, Inc. ATM antibody to perform western blot in order to investigate the relations between MRN and ATM [ncbi , more ] in 2008 and Han Li et al. used Rockland Immunochemicals, Inc. ATM antibody to investigate the role of Chk2 in the regulation of HSV-1 ICP0-mediated G2/M arrest and virus growth [ncbi , more ]. In 2006, Carlos E Irarrazabal et al. applied Rockland Immunochemicals, Inc. ATM antibody to investigate the mechanism of the PI3K-IA (phosphatidylinositol 3-kinase Class IA) lipid kinase activity was affected by high NaCl and ionizing radiation [ncbi , more ]. Rockland Immunochemicals, Inc. ATM antibody was employed in 2005 to study DNA Damage-induced ATM association with its target proteins [ncbi , more ], to study methylator-induced mismatch repair-dependent G2 arrest in human diploid foreskin fibroblasts [ncbi , more ], to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs) [ncbi , more ]and to identify the ATM domains for nuclear localization and chromatin association [ncbi , more ].
EpitomicsEpitomics ATM product
  • western blotIn 2009, Rachel A Schwartz et al. applied Epitomics ATM antibody to carry out western blot analysis in order to investigate the effect of adeno-associated virus and adenovirus coinfection on inducing cellular DNA damage response [ncbi , more ]. Wen Hsing Cheng et al. utilized Epitomics ATM antibody to carry out western blot analysis in order to investigate the role for WRN in ATM pathway activation and the S-phase checkpoint in cells exposed to DNA interstrand cross-link-induced double-strand breaks [ncbi , more ] in 2008 and Seema S Lakdawala et al. used Epitomics ATM antibody to perform western blot in order to identify that regions of Nbs1 are differentially required for concatemer formation and inhibition of Ad DNA replication [ncbi , more ].
Sigma-AldrichSigma-Aldrich ATM product
  • immunoprecipitationIn 2008, Lei Li et al. used Sigma-Aldrich ATM antibody to study the role for DEAD Box 1 in the repair of transcriptionally active regions of the genome [ncbi , more ].
NOVUS BIO
  • western blotIn 2009, Alejo Efeyan et al. employed ATM antibody to suggest that ATM plays a role in oncogene-induced senescence or in p53-dependent tumor suppression [ncbi , more ].
Articles Reviewed
  1. Aniek Janssen et al. (2011). "Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations".PMID 21960636
  2. Zhi Guo et al. (2010). "ATM activation by oxidative stress".PMID 20966255
  3. Jay P Reddy et al. (2010). "Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation".PMID 20133707
  4. Alejo Efeyan et al. (2009). "Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression".PMID 19421407
  5. Rachel A Schwartz et al. (2009). "Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase".PMID 19339345
  6. Julia Leemput et al. (2009). "ATM localization and gene expression in the adult mouse eye".PMID 19234633
  7. Bettina Gruhne et al. (2009). "The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species".PMID 19139406
  8. Yong Chul Kim et al. (2009). "Activation of ATM depends on chromatin interactions occurring before induction of DNA damage".PMID 19079244
  9. Stéphanie Solier et al. (2009). "Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways".PMID 18955500
  10. Jennifer Hein et al. (2009). "Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding".PMID 18922873
  11. Susanne Burdak-Rothkamm et al. (2008). "ATM acts downstream of ATR in the DNA damage response signaling of bystander cells".PMID 18757420
  12. Lei Li et al. (2008). "A role for DEAD box 1 at DNA double-strand breaks".PMID 18710941
  13. Ali Jazayeri et al. (2008). "Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity".PMID 18596698
  14. Wen Hsing Cheng et al. (2008). "WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks".PMID 18596239
  15. Seema S Lakdawala et al. (2008). "Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation".PMID 18562516
  16. Jean Luc Perfettini et al. (2008). "Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia".PMID 18560558
  17. Suchismita Panda et al. (2008). "Modification of the ATM/ATR directed DNA damage response state with aging and long after hepatocyte senescence induction in vivo".PMID 18440596
  18. Ching Tai Lin et al. (2008). "Valproic acid resensitizes cisplatin-resistant ovarian cancer cells".PMID 18429963
  19. Hong Zhao et al. (2008). "Oxidative stress induces cell cycle-dependent Mre11 recruitment, ATM and Chk2 activation and histone H2AX phosphorylation".PMID 18418078
  20. Han Li et al. (2008). "Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth".PMID 18321553
  21. Masahiro Nakashima et al. (2008). "Foci formation of P53-binding protein 1 in thyroid tumors: activation of genomic instability during thyroid carcinogenesis".PMID 17985346
  22. Rekha Rai et al. (2006). "BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer".PMID 16872911
  23. Carlos E Irarrazabal et al. (2006). "Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation".PMID 16728507
  24. Xuan Huang et al. (2006). "Sequential phosphorylation of Ser-10 on histone H3 and ser-139 on histone H2AX and ATM activation during premature chromosome condensation: relationship to cell-cycle phase and apoptosis".PMID 16528736
  25. Wei Zhang et al. (2005). "The role of Polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation".PMID 16157594
  26. Noriko Shirata et al. (2005). "Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection".PMID 15964848
  27. David B Young et al. (2005). "Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association".PMID 15929992
  28. Xiaohui Bi et al. (2005). "DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint".PMID 15817457
  29. Norvin Fernandes et al. (2005). "DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM".PMID 15713674
  30. Aaron W Adamson et al. (2005). "Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2".PMID 15647386
  31. Masanori Terai et al. (2005). "Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway".PMID 15647378
  32. Ayumi Kudoh et al. (2005). "Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment".PMID 15611093
  33. Joshua Silverman et al. (2004). "Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint".PMID 15342490
  34. Zhi Xiang Xu et al. (2003). "PML colocalizes with and stabilizes the DNA damage response protein TopBP1".PMID 12773567
  35. Zhenkun Lou et al. (2003). "Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control".PMID 12611903
  36. Heather Beamish et al. (2002). "Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM".PMID 12034743
  37. Shaun P Scott et al. (2002). "Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer".PMID 11805335
  38. S A Lee et al. (2001). "Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2".PMID 11278277