This is a review about ASK1, based on 9 published articles (read how Labome selects the articles), using ASK1 antibody in all methods. It is aimed to help Labome visitors find the most suited ASK1 antibody.
ASK1 synonym: ASK1; MAPKKK5; MEKK5; ASK-1; MAP/ERK kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1

Santa Cruz Biotechnology
rabbit polyclonal (H-300)
  • WB; human
Santa Cruz Biotechnology ASK1 antibody (Santa Cruz, sc-7931) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal (H-300)
  • WB; mouse
Santa Cruz Biotechnology ASK1 antibody (Santa Cruz, sc7931) was used in western blot on mouse samples. Basic Res Cardiol (2015) ncbi
rabbit polyclonal (Ser 966)
  • WB; mouse
Santa Cruz Biotechnology ASK1 antibody (Santa Cruz, sc101634) was used in western blot on mouse samples. Basic Res Cardiol (2015) ncbi
rabbit polyclonal (H-300)
  • WB; human; 1:5.00
In order to study the effect of caffeic acid phenethyl ester on CD133+ melanoma, Santa Cruz Biotechnology ASK1 antibody (Santa Cruz Biotechnology, Sc-7931) was used in western blot on human samples at 1:5.00. Cancer Lett (2015) ncbi
rabbit polyclonal (H-300)
  • IP; mouse; 1:100; fig 1g
Santa Cruz Biotechnology ASK1 antibody (Santa, sc-7931) was used in immunoprecipitation on mouse samples at 1:100 (fig 1g). Sci Signal (2013) ncbi
not indicated
  • WB; human
  • IHC; human
Santa Cruz Biotechnology ASK1 antibody was used in western blot and immunohistochemistry to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth.Mol Cell Biol (2006) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-ASK1 antibody was used in HCT116, IMR90, and U2OS cells and in western blot to study the apoptotic transcriptional network affected by HDAC inhibitor suberoylanilide hydroxamic acid (SAHA) in cancer cells with inducible E2F1.J Biol Chem (2006) ncbi
not indicated
  • IP; human
Santa Cruz Biotechnology anti-ASK1 (H300) antibody was used in immunoprecipitation to study JNK activation by H2O2J Biol Chem (2005) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology anti-ASK1 (H300) antibody was used in western blot to study tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1J Biol Chem (2005) ncbi
Cell Signaling Technology
rabbit monoclonal (D11C9)
  • WB; human
Cell Signaling Technology ASK1 antibody (Cell Signaling Technology, 8662) was used in western blot on human samples. Biochim Biophys Acta (2014) ncbi
rabbit polyclonal
  • WB; human
Cell Signaling Technology ASK1 antibody (Cell Signaling Technology, 3765) was used in western blot on human samples. Biochim Biophys Acta (2014) ncbi
not indicated
  • WB; human
Cell Signaling phospho-ASK1 (Ser967) antibody was used in western blot to demonstrate direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth.Mol Cell Biol (2006) ncbi
not indicated
  • WB; human
Cell Signaling rabbit polyclonal phopsho-ASK1 (pSer-967 and pThr-845) antibodies were used in western blot to study JNK activation by H2O2J Biol Chem (2005) ncbi
not indicated
  • WB; human
Cell Signaling rabbit polyclonal phospho-ASK1 (Ser (P) 967 and Thr (P) 845) antibody was used in western blot to study tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1J Biol Chem (2005) ncbi
Articles Reviewed
  1. Jing Pan et al. (2015). "Small peptide inhibitor of JNK3 protects dopaminergic neurons from MPTP induced injury via inhibiting the ASK1-JNK3 signaling pathway".PMID 25856433
  2. Ming wei Bao et al. (2015). "Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction".PMID 25840773
  3. Abdelouahid El-Khattouti et al. (2015). "CD133⁺ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: significance for melanoma treatment".PMID 25449786
  4. Musarat Ishaq et al. (2014). "Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system".PMID 25173814
  5. Peixin Yang et al. (2013). "Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects".PMID 23982205
  6. Qinghang Liu et al. (2006). "Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth".PMID 16648474
  7. Jing Tan et al. (2006). "Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity".PMID 16476732
  8. Wei Zhang et al. (2005). "Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor".PMID 15755722
  9. Xianghong Li et al. (2005). "Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation".PMID 15701637