This is a review about APP, based on 226 published articles (read how Labome selects the articles), using APP antibody in all methods. It is aimed to help Labome visitors find the most suited APP antibody.
APP synonym: AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid precursor protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II

BioLegend
rabbit monoclonal (BA3-9)
  • ELISA; human
In order to investigate how glimepiride protects neurons against synapse damage induced by Abeta, BioLegend APP antibody (Covance, BA3-9) was used in ELISA on human samples. Neuropharmacology (2016) ncbi
mouse monoclonal (4G8)
  • IP; mouse
BioLegend APP antibody (Covance, 4G8) was used in immunoprecipitation on mouse samples. Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (M3.2)
  • WB; rat; 1:1000
In order to localize ADAM10 and BACE1 in synaptic vesicles, BioLegend APP antibody (BioLegend, SIG-39155) was used in western blot on rat samples at 1:1000. J Neurochem (2015) ncbi
mouse monoclonal (4G8)
  • IHC; mouse; 1:100
BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry on mouse samples at 1:100. Mol Neurodegener (2015) ncbi
rabbit polyclonal (Poly8134)
  • WB; mouse; 1:500
BioLegend APP antibody (BioLegend, 813401) was used in western blot on mouse samples at 1:500. Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (M3.2)
  • IP; mouse; 1:300
  • WB; mouse; 1:800
BioLegend APP antibody (BioLegend, 805701) was used in immunoprecipitation on mouse samples at 1:300 and in western blot on mouse samples at 1:800. Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (C1/6.1)
  • WB; mouse; 1:1000
BioLegend APP antibody (BioLegend, 802802) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (4G8)
  • IHC; human; 1:500
In order to characterize the neuropathological features of dystonias, BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry on human samples at 1:500. Tremor Other Hyperkinet Mov (N Y) (2015) ncbi
mouse monoclonal (6E10)
  • WB; fruit fly
BioLegend APP antibody (Signet Laboratories, 6E-10) was used in western blot on fruit fly samples. Amyloid (2015) ncbi
mouse monoclonal (6E10)
  • IHC-Free; mouse; 1:200
BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - free floating section on mouse samples at 1:200. Brain (2015) ncbi
mouse monoclonal (4G8)
  • IHC-F; human
BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - frozen section on human samples. Nucl Med Biol (2015) ncbi
mouse monoclonal (6E10)
  • WB; human
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples. Biochemistry (2015) ncbi
mouse monoclonal (6E10)
  • IP; human
BioLegend APP antibody (Covance, 6E10) was used in immunoprecipitation on human samples. J Biol Chem (2015) ncbi
mouse monoclonal (6E10)
  • IHC; mouse; 1:500
BioLegend APP antibody (Signet, SIG-39300) was used in immunohistochemistry on mouse samples at 1:500. Brain Struct Funct (2015) ncbi
mouse monoclonal (6E10)
  • WB; rat
BioLegend APP antibody (Covance, 6E10) was used in western blot on rat samples. Biomed Res Int (2015) ncbi
mouse monoclonal (4G8)
  • IHC-Free; mouse
In order to explore a nonpharmacological approach, repeated scanning ultrasound treatments, for removing Abeta and restoring memory function in a mouse model of Alzheimer's disease, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry - free floating section on mouse samples. Sci Transl Med (2015) ncbi
mouse monoclonal (4G8)
  • WB; human; 1:500
In order to study neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease in mice, BioLegend APP antibody (Covance, 4G8) was used in western blot on human samples at 1:500. J Neuropathol Exp Neurol (2015) ncbi
mouse monoclonal (4G8)
  • IHC; human; 1:400
BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:400. Neurobiol Aging (2015) ncbi
mouse monoclonal (4G8)
  • IHC; human; 1:1000
BioLegend APP antibody (Covance, SIG39220) was used in immunohistochemistry on human samples at 1:1000. F1000Res (2014) ncbi
mouse monoclonal (6E10)
  • IHC; mouse; 1:500
In order to assess the neuroprotective effect of quercetin administration in the triple transgenic Alzheimer's disease model mice, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:500. Neuropharmacology (2015) ncbi
mouse monoclonal (C1/6.1)
  • WB; mouse; 1:1000; fig 8
In order to characterize cognitive and neuropathological Alzheimer's disease markers in a novel mouse model, BioLegend APP antibody (Covance, SIG-39152) was used in western blot on mouse samples at 1:1000 (fig 8). Age (Dordr) (2015) ncbi
mouse monoclonal (6E10)
  • IHC-P; mouse; 1:600
BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - paraffin section on mouse samples at 1:600. Alzheimer Dis Assoc Disord (2015) ncbi
mouse monoclonal (6E10)
  • WB; rat; 1:1000
  • IHC; rat
BioLegend APP antibody (Covance, SIG-39320) was used in western blot on rat samples at 1:1000 and in immunohistochemistry on rat samples. J Exerc Nutrition Biochem (2014) ncbi
mouse monoclonal (6E10)
  • ELISA; human; 1:1000
  • IHC-P; human; 1:300
BioLegend APP antibody (Covance, 6E10) was used in ELISA on human samples at 1:1000 and in immunohistochemistry - paraffin section on human samples at 1:300. Neuropathol Appl Neurobiol (2015) ncbi
mouse monoclonal (6E10)
  • IHC; mouse; 1:1000
In order to investigate hypercholesterolemia at various stages of Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39300) was used in immunohistochemistry on mouse samples at 1:1000. Mol Cell Neurosci (2014) ncbi
mouse monoclonal (4G8)
  • IHC; mouse; 1:150
BioLegend APP antibody (Covance, Sig-39220) was used in immunohistochemistry on mouse samples at 1:150. Neurosci Lett (2015) ncbi
mouse monoclonal (6E10)
  • WB; human; 1:1000
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (4G8)
  • IHC-F; rat; 1:4000
BioLegend APP antibody (Signet, #39240) was used in immunohistochemistry - frozen section on rat samples at 1:4000. Adv Alzheimer Dis (2014) ncbi
mouse monoclonal (4G8)
  • WB; human; 1:1000
In order to discuss decontaminating medical devices of pathological amyloid-beta-, tau- and alpha-synuclein aggregates, BioLegend APP antibody (Covance, SIG-39220) was used in western blot on human samples at 1:1000. Acta Neuropathol Commun (2014) ncbi
mouse monoclonal (4G8)
  • IC; mouse; 1:1000
BioLegend APP antibody (Covance, 4G8) was used in immunocytochemistry on mouse samples at 1:1000. Neurobiol Aging (2015) ncbi
mouse monoclonal (4G8)
  • IHC-Free; rat; 1:200
In order to study the impact of amyloid-beta oligomers in the brains of rats and adult cynomolgus macaques, BioLegend APP antibody (Covance, SIG-39220-200) was used in immunohistochemistry - free floating section on rat samples at 1:200. J Neurosci (2014) ncbi
mouse monoclonal (6E10)
  • WB; Rhesus monkey; 1:1000
In order to study the impact of amyloid-beta oligomers in the brains of rats and adult cynomolgus macaques, BioLegend APP antibody (Covance, SIG-39300-200) was used in western blot on Rhesus monkey samples at 1:1000. J Neurosci (2014) ncbi
mouse monoclonal (6E10)
  • WB; human
  • IC; human
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples and in immunocytochemistry on human samples. J Biol Chem (2014) ncbi
mouse monoclonal (4G8)
  • IHC-Free; mouse; 1:250
In order to investigate the role of membrane-anchored versus soluble CX3CL1 in regulating the microglia-mediated amelioration of Abeta pathology, BioLegend APP antibody (Signet Laboratories, SIG-39200-1000) was used in immunohistochemistry - free floating section on mouse samples at 1:250. J Neurosci (2014) ncbi
mouse monoclonal (6E10)
  • IHC-Free; human; 1:2500
  • WB; human; 1:2500
In order to correlate TREM2 expression with neurodegenerative markers in Alzheimer's disease, BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - free floating section on human samples at 1:2500 and in western blot on human samples at 1:2500. Brain Pathol (2015) ncbi
mouse monoclonal (4G8)
  • ELISA; mouse
  • IHC; mouse; 1 ng/ ul
BioLegend APP antibody (Covance, 4G8) was used in ELISA on mouse samples and in immunohistochemistry on mouse samples at 1 ng/ ul. J Biol Chem (2014) ncbi
mouse monoclonal (4G8)
  • IHC-P; human; 1:1000
In order to investigate the relationship between ZnT3 and PSD95, cognition and pathology, BioLegend APP antibody (Covance, SIG-39220-200) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Neurobiol Aging (2014) ncbi
mouse monoclonal (4G8)
  • ELISA; human
  • IP; human
  • WB; human
In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, BioLegend APP antibody (Covance, 4G8) was used in ELISA on human samples, in immunoprecipitation on human samples, and in western blot on human samples. Int J Alzheimers Dis (2014) ncbi
mouse monoclonal (6E10)
  • IC; human; 1:50
In order to assess the presence of granulovacuolar degeneration and the activated unfolded protein response in two mouse models of Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in immunocytochemistry on human samples at 1:50. Neurobiol Dis (2014) ncbi
mouse monoclonal (6E10)
  • WB; human
In order to study the relationship of an Alzheimer's disease-linked SNP in the CLU gene and Tau, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples. PLoS ONE (2014) ncbi
mouse monoclonal (6E10)
  • WB; mouse; 1:2000
  • WB; rat; 1:2000
In order to investigate the mechanism for the neuroprotective effect of Klotho, BioLegend APP antibody (Covance, SIG-39300) was used in western blot on mouse samples at 1:2000 and on rat samples at 1:2000. J Biol Chem (2014) ncbi
mouse monoclonal (6E10)
  • WB; human; 1:5000
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:5000. PLoS ONE (2014) ncbi
mouse monoclonal (6E10)
  • WB; mouse; 1:2500
In order to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on mouse samples at 1:2500. J Neurosci (2014) ncbi
mouse monoclonal (6E10)
  • WB; mouse; 1:500
In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in western blot on mouse samples at 1:500. J Neurosci (2014) ncbi
mouse monoclonal (4G8)
  • IHC-F; mouse; 1:500
BioLegend APP antibody (Covance, SIG-39220) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Alzheimers Dis (2014) ncbi
mouse monoclonal (6E10)
  • IHC; human; 1 ug/ml
BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on human samples at 1 ug/ml. J Alzheimers Dis (2014) ncbi
mouse monoclonal (6E10)
  • WB; human; 1:1000
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples at 1:1000. Nanomedicine (2014) ncbi
mouse monoclonal (6E10)
  • IHC-Free; mouse
  • WB; mouse
BioLegend APP antibody (Covance Research Products, 6E10) was used in immunohistochemistry - free floating section on mouse samples and in western blot on mouse samples. Am J Pathol (2014) ncbi
mouse monoclonal (6E10)
  • WB; human
In order to evaluate a novel insulin/IGF signaling pathway inhibitor for its protective effect on age-onset, neurodegeneration-linked proteotoxicity, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on human samples. Aging Cell (2014) ncbi
mouse monoclonal (6E10)
  • IHC-F; mouse; 1:1500
BioLegend APP antibody (Covance Inc., 6E10) was used in immunohistochemistry - frozen section on mouse samples at 1:1500. Acta Neuropathol Commun (2013) ncbi
mouse monoclonal (6E10)
  • IHC-Free; mouse; 1:2000
BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry - free floating section on mouse samples at 1:2000. J Alzheimers Dis (2014) ncbi
mouse monoclonal (6E10)
  • IP; mouse
In order to investigate the role of microglial derived tumor necrosis factor alpha in neuronal cell cycle progression, BioLegend APP antibody (Covance, SIG-39300) was used in immunoprecipitation on mouse samples. Neurobiol Dis (2014) ncbi
mouse monoclonal (6E10)
  • WB; mouse; 1:1000
In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, BioLegend APP antibody (Covance, SIG-39320) was used in western blot on mouse samples at 1:1000. J Neurotrauma (2014) ncbi
mouse monoclonal (6E10)
  • WB; human; 1:1000
In order to study the role of NG2 oligodendroglial precursor cells in the autophagic removal of Abeta peptides, BioLegend APP antibody (Signet, sig-39320) was used in western blot on human samples at 1:1000. Mol Neurodegener (2013) ncbi
rabbit polyclonal (Poly18058)
  • WB; mouse; 1:1000
BioLegend APP antibody (Signet, SIG-39153) was used in western blot on mouse samples at 1:1000. J Neurosci (2013) ncbi
mouse monoclonal (6E10)
  • IHC-P; mouse; 1:300
  • WB; mouse; 1:1000
BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 and in western blot on mouse samples at 1:1000. Apoptosis (2013) ncbi
mouse monoclonal (6E10)
  • IHC; mouse; 1:200
BioLegend APP antibody (Signet, 6E10) was used in immunohistochemistry on mouse samples at 1:200. Transl Psychiatry (2013) ncbi
mouse monoclonal (6E10)
  • IHC; human
In order to study the formation of amylin amyloid deposits in the cerebrovascular system and the implications for Alzheimer's disease, BioLegend APP antibody (Covance, 6E10) was used in immunohistochemistry on human samples. Ann Neurol (2013) ncbi
mouse monoclonal (6E10)
  • IHC-F; human; 2 ug/ml
BioLegend APP antibody (Covance, SIG-39320) was used in immunohistochemistry - frozen section on human samples at 2 ug/ml. Neuropathol Appl Neurobiol (2014) ncbi
mouse monoclonal (4G8)
  • IHC; human; 1:200
In order to study changes in autophagy and the roles of Tau hyperphosphorylation and fractalkine in an animal model of Abeta42-induced Tau hyperphosphorylation, BioLegend APP antibody (Covance, 4G8) was used in immunohistochemistry on human samples at 1:200. Exp Neurol (2014) ncbi
mouse monoclonal (6E10)
  • IHC; mouse; 1:200
BioLegend APP antibody (Convance, SIG-39320) was used in immunohistochemistry on mouse samples at 1:200. J Alzheimers Dis (2013) ncbi
not indicated
  • WB; human
Covance anti-beta Amyloid was used in 1:1,000 to perform western blot in order to show that yeast could be used to model Abeta toxicity for potential modifier screen.Science (2011) ncbi
mouse monoclonal (6E10)
  • WB; human
In order to investigate the role of growth arrest-specific 1 in Alzheimer's disease, BioLegend APP antibody (Signet, 6E10) was used in western blot on human samples. Hum Mol Genet (2011) ncbi
mouse monoclonal (6E10)
  • WB; human
BioLegend APP antibody (Covance, 6E10) was used in western blot on human samples. Neurobiol Aging (2012) ncbi
not indicated
  • IHC; human
Covance anti-Amyloid beta monoclonal antibody (6E10, 1:2,000 dilution) was used to perform immunohistochemistry and western blot in order to clarify that Amyloid beta is an antimicrobial peptide that may normally function in the innate immune system.PLoS ONE (2010) ncbi
not indicated
  • WB; human
Covance antibody 6E10 was used to detect APP in western blot in order to find out the different regulation of E22Q-mutant A beta peptide towards vascular amyloid and parenchymal A beta depositionAm J Pathol (2009) ncbi
not indicated
  • IP; human
Signet Laboratories monoclonal anti-Abeta antibody 6E10 was used in immunoprecipitation to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cellsAm J Pathol (2009) ncbi
not indicated
  • Neut; human
Signet monoclonal anti-Abeta antibody (1 ug/ml) was used in cell culture in order to study the role of NGF or BDNF signaling in neuronal apoptotic deathProc Natl Acad Sci U S A (2008) ncbi
not indicated
  • IHC; human
Senetek anti-amyloid-beta peptide (Abeta) antibody (4G8) was used in immunohistochemistry to study whether PGRN genetic variability contributed to other common neurodegenerative brain diseases, such as Alzheimer disease (AD) or Parkinson disease (PD) in sections from human.Arch Neurol (2007) ncbi
not indicated
  • IHC; human
Signet amyloid beta-protein antibody was used in immunohistochemistry to study the muscle protein dysferlin accumulates in the Alzheimer brain.Acta Neuropathol (2006) ncbi
not indicated
  • WB; human
Signet Laboratories anti-sAPP alpha antibody (6E10) was used in human cells and in western blot to study the role for ubiquilin 1 in modulating amyloid precursor protein trafficking and Abeta secretion.J Biol Chem (2006) ncbi
not indicated
  • IHC; human
  • IC; human
Signet Laboratories mouse anti amyloid-beta protein antibody was used in immunohistochemistry and immunocytochemistry to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.J Cell Biol (2005) ncbi
not indicated
  • WB; human
  • IP; human
Signet APP monoclonal antibody 6E10 was used in western blot and immunoprecipitation to investigate the binding of the BRI2 to APP precursor proteinJ Biol Chem (2005) ncbi
not indicated
  • WB; human
Signet APP monoclonal antibody 6E10 was used in western blot to study the reduced secretion of APP and Abeta through the inhibition of glycosphingolipid biosynthesisJ Biol Chem (2005) ncbi
not indicated
  • WB; human
Senetek monoclonal 6E10 antibody that recognizes residues 1 17 of the Abeta domain of soluble APP alpha was used in western blot to study the effect of P2Y2 nucleotide receptors on alpha-secretase-dependent amyloid precursor protein processingJ Biol Chem (2005) ncbi
not indicated
  • IP; human
Senetek monoclonal amyloid beta antibody 4G8 was used in immunoprecipitation to study the biological function of presenilin-1 maturation.J Biol Chem (2005) ncbi
not indicated
  • WB; human
Signet Laboratories C99 antibody 6E10 was used in Western blot to study the biological function of Gamma-secretase.J Biol Chem (2005) ncbi
Invitrogen
mouse monoclonal (LN27)
  • WB; human; 1:400
In order to investigate the role of cholesterol in the pathogenesis of Alzheimer's disease, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples at 1:400. J Neurodegener Dis (2013) ncbi
rabbit polyclonal
  • WB; human
In order to show that IDN5706 promotes iAPP degradation by activating Atg5-dependent autophagy, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples. PLoS ONE (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:250
In order to demonstrate that liraglutide has prophylactic properties in Alzheimer's disease models, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry on mouse samples at 1:250. Behav Brain Res (2015) ncbi
rabbit polyclonal
  • IHC; human
In order to study the role of apolipoprotein E in cerebral amyloid angiopathy, Invitrogen APP antibody (Invitrogen, 715800) was used in immunohistochemistry on human samples. J Neurochem (2015) ncbi
rabbit polyclonal
  • IHC; mouse
In order to describe the development of a closed-body model of spinal cord injury in mice, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on mouse samples. Exp Neurol (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:400
In order to investigate butyrylcholinesterase activity in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry on mouse samples at 1:400. Neuroscience (2015) ncbi
rabbit monoclonal (H31L21)
  • IHC-F; mouse
Invitrogen APP antibody (Invitrogen, H31L21) was used in immunohistochemistry - frozen section on mouse samples. J Neurosci (2015) ncbi
mouse monoclonal (LN27)
  • IHC-P; mouse; 1:100
In order to investigate the spread of neuronal pathology, Invitrogen APP antibody (Life Technologies, 13-0200) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Neuropathol Appl Neurobiol (2015) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:1000; fig 6
  • IHC; mouse; 1:50; fig 5
In order to discuss the limitations assessing axonal injury by microscopy, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 6) and in immunohistochemistry on mouse samples at 1:50 (fig 5). J Neurosci Methods (2015) ncbi
rabbit polyclonal
  • IC; mouse; 1:100; fig 2
In order to investigate the contribution of TREM2 to microglia function in vivo, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunocytochemistry on mouse samples at 1:100 (fig 2). Acta Neuropathol (2015) ncbi
rabbit polyclonal
  • IHC-Free; mouse; 1:700
In order to characterize axonal injury over time, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples at 1:700. Acta Neuropathol (2015) ncbi
rabbit polyclonal
  • IHC-F; rat; 1:400
In order to examine the role of the monoaminergic system in mild blast-induced traumatic brain injury, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on rat samples at 1:400. J Neurotrauma (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:500
In order to identify the relation between fragile X mental retardation protein and Alzheimer disease, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples at 1:500. Front Genet (2014) ncbi
rabbit polyclonal
  • IHC; mouse; 1:200
In order to investigate hypercholesterolemia at various stages of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry on mouse samples at 1:200. Mol Cell Neurosci (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:250
In order to demonstrate that GLP-1 receptor agonists are therapeutic for Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:250. Neuropharmacology (2014) ncbi
rabbit polyclonal
  • WB; human
In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples. Int J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • IHC-Free; rat; 1:1000
In order to assess if subischemic levels of elevated intracranial pressure without hematoma/contusion contribute to increased morbidity/mortality, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - free floating section on rat samples at 1:1000. J Cereb Blood Flow Metab (2014) ncbi
rabbit monoclonal (H31L21)
  • IC; human; 1:2000
In order to investigate the contribution of GABA inhibition in the dentate gyrus in Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 700254) was used in immunocytochemistry on human samples at 1:2000. Nat Commun (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:500
In order to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure, Invitrogen APP antibody (Zymed/Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurosci (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:1000
In order to study the contribution of microglia to axon degeneration after repetitive closed-skull traumatic brain injury using CD11b-thymidine kinase mice, Invitrogen APP antibody (Invitrogen, 512700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Neurotrauma (2014) ncbi
mouse monoclonal (BAM01 (6F/3D))
  • IHC; human; 1:100
In order to investigate the protein expression of G-CSF and its receptor in the adult human brain, Invitrogen APP antibody (Pierce Biotechnology, Clone 6F/3D) was used in immunohistochemistry on human samples at 1:100. J Anat (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:2000; fig 6
In order to assess temporal and spatial onset of the reactive glia response in a clinically relevant form of Pelizaeus-Merzbacher disease, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:2000 (fig 6). J Neuroinflammation (2013) ncbi
mouse monoclonal (LN27)
  • IHC; Rhesus monkey; fig 4
In order to explain how CCR5 antagonists may attenuate central nervous system disease by modulating inflammatory signaling and by limiting HIV replication, Invitrogen APP antibody (Zymed, Clone LN27) was used in immunohistochemistry on Rhesus monkey samples (fig 4). AIDS (2013) ncbi
rabbit monoclonal (H31L21)
  • IHC-F; mouse; 1:500
In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, Invitrogen APP antibody (Invitrogen, 700254) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurotrauma (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:1000
In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Neurotrauma (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:250; fig 4
In order to test if Liraglutide has restorative effects in late-stage Alzheimer's disease in mice, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4). Neuropharmacology (2014) ncbi
rabbit monoclonal (H31L21)
  • IC; human
  • WB; human
In order to study the role of NG2 oligodendroglial precursor cells in the autophagic removal of Abeta peptides, Invitrogen APP antibody (Invitrogen, 700254) was used in immunocytochemistry on human samples and in western blot on human samples. Mol Neurodegener (2013) ncbi
rabbit monoclonal (H31L21)
  • WB; human; 1:2500
In order to study levels of BACE1 and Abeta42 in aged patients with cerebral atherosclerosis in the absence of dementia, Invitrogen APP antibody (Invitrogen, 700254) was used in western blot on human samples at 1:2500. Curr Alzheimer Res (2013) ncbi
rabbit polyclonal
  • IHC; domestic ferret; 1:5000
In order to characterize the behavioral, structural, and histological changes in juvenile ferrets following induction of hydrocephalus, Invitrogen APP antibody (Invitrogen, 36-6900) was used in immunohistochemistry on domestic ferret samples at 1:5000. Exp Neurol (2013) ncbi
mouse monoclonal (LN27)
  • WB; human; fig 1
In order to identify agents that can reduce Abeta levels in the brain, Invitrogen APP antibody (Invitrogen, LN27) was used in western blot on human samples (fig 1). J Biol Chem (2013) ncbi
rabbit polyclonal
  • IHC; mouse; 1:250; fig 6
In order to test if D-Ala2GIP protects mice with advanced staged Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry on mouse samples at 1:250 (fig 6). J Alzheimers Dis (2013) ncbi
rabbit monoclonal (MABP2 1)
  • WB; mouse; 1:2000; fig 2
In order to study the effects of the herbal medicine TongLuoJuiNao on levels of BACE1, gamma secretase components, and beta-amyloid production in a murine model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 44-100) was used in western blot on mouse samples at 1:2000 (fig 2). PLoS ONE (2013) ncbi
rabbit polyclonal
  • WB; rat; fig 3
In order to assess myelin loss and oligodendrocyte death following traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51 2700) was used in western blot on rat samples (fig 3). Eur J Neurosci (2013) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:200; fig 4
In order to study the use of a retro-inverso peptide inhibitor to treat a murine model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4). PLoS ONE (2013) ncbi
mouse monoclonal (LN27)
  • IC; human
In order to describe the intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system, Invitrogen APP antibody (Zymed, LN27) was used in immunocytochemistry on human samples. Transl Neurodegener (2012) ncbi
rabbit polyclonal
  • ELISA; mouse; 1:500; fig 1
In order to study cholinergic dysfunction in a murine model of Alzheimer's disease, Invitrogen APP antibody (Zymed, 71-5800) was used in ELISA on mouse samples at 1:500 (fig 1). Behav Brain Res (2013) ncbi
rabbit polyclonal
  • IHC; human; 1:100; fig 1
In order to determine the distribution pattern, cellular source, and activity of tissue transglutaminase in cerebral amyloid angiopathy, Alzheimer's disease, and hereditary cerebral hemorrhage with amyloidosis of the Dutch type cases, Invitrogen APP antibody (Invitrogen, 715800) was used in immunohistochemistry on human samples at 1:100 (fig 1). Neurobiol Aging (2013) ncbi
rabbit polyclonal
  • IHC-Free; human; 1:10000; fig 6
In order to examine the effect on the anti-inflammatory, MW01-2-151SRM, in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 44338100) was used in immunohistochemistry - free floating section on human samples at 1:10000 (fig 6). J Neurosci (2012) ncbi
rabbit polyclonal
  • IHC; rat; 1:1000; fig 2
In order to study the neuronal somatic and axonal damage that occurs during elevated intracranial pressure, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on rat samples at 1:1000 (fig 2). J Cereb Blood Flow Metab (2012) ncbi
rabbit polyclonal
  • IHC; rat; fig 4
In order to investigate diffuse axonal injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on rat samples (fig 4). J Trauma Acute Care Surg (2012) ncbi
mouse monoclonal (LN27)
  • WB; human; 1:1000; fig 3, 4
In order to study the role of receptor tyrosine kinase Tyro3 in APP processing and beta amyloid deposition, Invitrogen APP antibody (ZYMED, 13-0200) was used in western blot on human samples at 1:1000 (fig 3, 4). PLoS ONE (2012) ncbi
rabbit polyclonal
  • IHC; rat; 1 ug/ml; fig 6
In order to perform a time course to study impaired axoplasmic transport and neurofilament compaction, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1 ug/ml (fig 6). Brain Res (2012) ncbi
rabbit polyclonal
  • IHC; mouse; 1:300; fig 2
In order to examine how changes in testosterone and luteinizing hormone contribute to Alzheimer's disease, Invitrogen APP antibody (Zymed, 71-5800) was used in immunohistochemistry on mouse samples at 1:300 (fig 2). Brain Res (2012) ncbi
rabbit polyclonal
  • WB; mouse; fig 2
In order to report that APP haploinsufficiency prevents memory dysfunctions seen in FBD(KI) mice, Invitrogen APP antibody (Invitrogen, 36-6900) was used in western blot on mouse samples (fig 2). J Neurosci (2012) ncbi
rabbit polyclonal
  • WB; mouse; fig 5
In order to elucidate the role of NADPH oxidase in traumatic brain injury, Invitrogen APP antibody (Invitrogen, 36-6900) was used in western blot on mouse samples (fig 5). PLoS ONE (2012) ncbi
rabbit polyclonal
  • IHC; mouse; 1:250; fig 8
In order to investigate dysregulated insulin signaling in Alzheimer's disease and diabetes, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry on mouse samples at 1:250 (fig 8). J Clin Invest (2012) ncbi
rabbit polyclonal
  • IHC-Free; mouse; 1:200; fig 1
In order to examine how ageing affects neurogenesis and oxidative stress in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (fig 1). Brain Res (2012) ncbi
mouse monoclonal (LN27)
  • WB; human; 1:250; fig 3
In order to elucidate the role of Kinesin-1 in Alzheimer disease pathogenesis, Invitrogen APP antibody (Invitrogen, LN27) was used in western blot on human samples at 1:250 (fig 3). PLoS ONE (2012) ncbi
rabbit polyclonal
  • IHC-P; mouse; 1:50; fig 8
In order to report the effects of NK-4 on the toxicity of Abeta, on cognitive function, and Abeta concentration in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Invitrogen, #71-5800) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 8). PLoS ONE (2012) ncbi
mouse monoclonal (LN27)
  • IHC; human; tbl 2
In order to investigate phagocytosis of neuronal antigens in a multiple sclerosis model, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry on human samples (tbl 2). Glia (2012) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:400; fig 1
In order to investigate the role of BuChE using the APPSWE/PSEN1dE9 transgenic mouse model, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:400 (fig 1). J Neuropathol Exp Neurol (2012) ncbi
mouse monoclonal (LN27)
  • IC; human; 1:100; fig 1
In order to study the contribution of macroautophagy to lysosomal Abeta accumulation, Invitrogen APP antibody (Zymed Laboratories, 13-0200) was used in immunocytochemistry on human samples at 1:100 (fig 1). Autophagy (2011) ncbi
mouse monoclonal (LN27)
  • WB; human; fig 1
In order to study the mechanism by which Gas1 blocks the intracellular trafficking of amyloid precursor protein, Invitrogen APP antibody (Zymed Laboratories, LN27) was used in western blot on human samples (fig 1). J Alzheimers Dis (2012) ncbi
rabbit polyclonal
  • IHC; mouse; 1:300; fig 1
In order to assess the effects of depleting both circulating and brain estrogen levels in a mouse model of Alzheimer's disease, Invitrogen APP antibody (Zymed, 71-5800) was used in immunohistochemistry on mouse samples at 1:300 (fig 1). Neurobiol Dis (2012) ncbi
rabbit polyclonal
  • IHC; rat; 1:200; fig 4
In order to discuss the use of helmets to prevent traumatic brain injury, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1:200 (fig 4). Neurosurgery (2012) ncbi
rabbit polyclonal
  • IHC; rat; 1 ug/ml; fig 7, 8
In order to study traumatic axonal injury in rats, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1 ug/ml (fig 7, 8). J Neurotrauma (2011) ncbi
rabbit polyclonal
  • WB; human; fig 4
In order to test if AbetaPP processing is altered in Familial Danish Dementia patients' brain samples, Invitrogen APP antibody (Invitrogen, 36-6900) was used in western blot on human samples (fig 4). J Alzheimers Dis (2011) ncbi
mouse monoclonal (LN27)
  • IC; mouse; fig 7
In order to identify and characterize LDL receptor class A domain containing 3, Invitrogen APP antibody (Zymed, clone LN27) was used in immunocytochemistry on mouse samples (fig 7). J Neurosci (2011) ncbi
rabbit polyclonal
  • IHC-F; rat; 1:200; fig 7
In order to characterize a rodent model of direct cranial blast injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 7). J Neurotrauma (2011) ncbi
rabbit polyclonal
  • WB; mouse; fig 2
In order to study APP/Bri2 complexes in a mouse model of familial Danish dementia, Invitrogen APP antibody (Invitrogen/Zymed, 36-6900) was used in western blot on mouse samples (fig 2). EMBO J (2011) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:250; fig 4
In order to examine the effects of peripherally injected liraglutide in an Alzheimer mouse model, Invitrogen APP antibody (Invitrogen, 71-5800) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4). J Neurosci (2011) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:200; fig 3
In order to investigate the effects of blast injury on the parenchymatous organs of mice, Invitrogen APP antibody (Zymed , 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3). J Neuropathol Exp Neurol (2011) ncbi
rabbit polyclonal
  • IHC; human; 1:100; fig 5
In order to examine the oligodendrogenic potential of different human fetal forebrain regions during the first trimester of gestation, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on human samples at 1:100 (fig 5). Brain (2011) ncbi
mouse monoclonal (LN27)
  • WB; human
  • IC; human
In order to investigate the role of growth arrest-specific 1 in Alzheimer's disease, Invitrogen APP antibody (Zymed Laboratories, LN27) was used in western blot on human samples and in immunocytochemistry on human samples. Hum Mol Genet (2011) ncbi
rabbit polyclonal
  • IHC-Free; mouse; 1:100
In order to investigate the effects of using either a rounded- or a flat-tip impactor to apply controlled cortical impact injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples at 1:100. J Neurotrauma (2011) ncbi
mouse monoclonal (LN27)
  • WB; human
In order to compare the serum immunoglobulin G reactivity profiles obtained using the full spectrum of human myelin-associated proteins of multiple sclerosis patients and healthy control subjects, Invitrogen APP antibody (Zymed, clone LN27) was used in western blot on human samples. J Neuropathol Exp Neurol (2010) ncbi
rabbit polyclonal
  • WB; mouse; 0.5 ug/ml
In order to test if proprotein convertase subtilisin/kexin type 9 modulates the levels of low-density lipoprotein receptor and other membrane-bound proteins in the adult mouse brain, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples at 0.5 ug/ml. J Lipid Res (2010) ncbi
not indicated
  • IP; human
Invitrogen rabbit anti-amyloid beta peptide antibody was used to perform immunoprecipitation in order to clarify that amyloid beta is an antimicrobial peptide that may normally function in the innate immune system.PLoS ONE (2010) ncbi
rabbit polyclonal
  • ELISA; human
  • WB; human; fig 3a
In order to study the effect of an oleanolic-glycoside saponin on anti-oxidant activity and Abeta levels in the brain of Tg2576 mice, Invitrogen APP antibody (Zymed, 51-2700) was used in ELISA on human samples and in western blot on human samples (fig 3a). Brain Res (2009) ncbi
not indicated
  • ELISA; human
Invitrogen amyloid beta protein ELISA kit was used to determine the cellular amyloid beta level in order to investigate the association of HNE-mediated HNP inactivation with amyloid beta accumulation.J Neurochem (2009) ncbi
not indicated
  • ELISA; human
BioSource International A beta enzyme-linked immunosorbent assay was used to confirm that L-685, 458 sufficiently inhibited secretase activity in order to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cellsAm J Pathol (2009) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000; fig 5
In order to study the mechanism by which behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice, Invitrogen APP antibody (Zymed Laboratories, 51-2700) was used in western blot on mouse samples at 1:1000 (fig 5). J Neurochem (2009) ncbi
not indicated
  • WB; human
Zymed-Invitrogen Immunodetection rabbit amyloid precursor protein antibody was used in western blot in order to demonstrate that cycles of Ub binding and monoubiquitination regulate the association of Rabex-5 with endosomes.EMBO J (2008) ncbi
mouse monoclonal (LN27)
  • IC; human; fig 2
In order to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A in Down syndrome brains, Invitrogen APP antibody (Zymed Laboratories, 13-0200) was used in immunocytochemistry on human samples (fig 2). J Neurochem (2008) ncbi
rabbit polyclonal
  • WB; human; fig 1
In order to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A in Down syndrome brains, Invitrogen APP antibody (Zymed Laboratories, 51-2700) was used in western blot on human samples (fig 1). J Neurochem (2008) ncbi
not indicated
  • IP; human
BioSource International mouse anti APP monoclonal antibody was used in immunoprecipitation to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.J Cell Biol (2005) ncbi
not indicated
  • WB; human
  • IP; human
Zymed APP ZMD.316 polyclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein.J Biol Chem (2005) ncbi
not indicated
  • WB; human
  • IP; human
CBIOSOURCE p2-1 APP monoclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein.J Biol Chem (2005) ncbi
mouse monoclonal (LN27)
  • IHC; African green monkey; 1:10000; tbl 1
In order to investigate the role 14-3-3 proteins in the pathogenesis of central nervous system, Invitrogen APP antibody (Zymed, Clone LN27) was used in immunohistochemistry on African green monkey samples at 1:10000 (tbl 1). J Neuropathol Exp Neurol (2005) ncbi
mouse monoclonal (LN27)
  • WB; human; fig 3
In order to investigate the role of Alcadein in Alzheimer's disease, Invitrogen APP antibody (Zymed, LN27) was used in western blot on human samples (fig 3). J Biol Chem (2003) ncbi
mouse monoclonal (LN27)
  • IHC; human; tbl 2
In order to investigate HIV/SIV CNS infection and damage, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry on human samples (tbl 2). J Neurovirol (2003) ncbi
rabbit monoclonal (MABP2 1)
  • ELISA; human; 0.25 ug/ml
In order to investigate the role of the -YENP- motif of the amyloid precursor protein, Invitrogen APP antibody (Biosource, mAbP2-1) was used in ELISA on human samples at 0.25 ug/ml. Neuroscience (2003) ncbi
rabbit monoclonal (MABP2 1)
  • FC; human; 2.5 ug/ml; fig 5
In order to test if autosomal recessive hypercholesterolemia alters A beta PP internalization, transport, or processing, Invitrogen APP antibody (BIOSOURCE, 44-100) was used in flow cytometry on human samples at 2.5 ug/ml (fig 5). J Biol Chem (2003) ncbi
rabbit polyclonal
  • WB; human; 0.2 ug/ml; fig 5
In order to elucidate the mechanism of action of 22R-hydroxycholesterol on Abeta-mediated toxicity, Invitrogen APP antibody (Zymed Laboratories, 71-5800) was used in western blot on human samples at 0.2 ug/ml (fig 5). J Neurochem (2002) ncbi
rabbit polyclonal
  • WB; mouse; 1:500; fig 3
In order to develop a novel method for the rapid detection of beta-amyloid aggregates in Alzheimer's patients and transgenic mouse models, Invitrogen APP antibody (Zymed, 71-5800) was used in western blot on mouse samples at 1:500 (fig 3). Alzheimer Dis Assoc Disord (2002) ncbi
mouse monoclonal (LN27)
  • IHC; pig-tailed macaque; fig 1
In order to investigate the mechanisms of axonal damage associated with HIV central nervous system infection, Invitrogen APP antibody (Zymed Laboratories, Clone LN27) was used in immunohistochemistry on pig-tailed macaque samples (fig 1). J Neuropathol Exp Neurol (2002) ncbi
mouse monoclonal (LN27)
  • WB; human; fig 6
In order to determine the role of endocytic compartments in beta-secretase processing of amyloid precursor protein, Invitrogen APP antibody (Zymed, clone LN27) was used in western blot on human samples (fig 6). Traffic (2001) ncbi
mouse monoclonal (LN27)
  • ELISA; human
In order to examine MG132 inhibition of beta-secretase cleavage, Invitrogen APP antibody (Zymed, LN27) was used in ELISA on human samples. J Biol Chem (2001) ncbi
mouse monoclonal (LN27)
  • IP; human; fig 3
  • WB; human; fig 8
In order to elucidate the regulatory role of human bleomycin hydrolase in the amyloid precursor protein processing pathways, Invitrogen APP antibody (Zymed Laboratories, clone LN27) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig 8). FASEB J (2000) ncbi
mouse monoclonal (LN27)
  • IC; human; fig 8
In order to characterize human X11-like, Invitrogen APP antibody (Zymed, LN27) was used in immunocytochemistry on human samples (fig 8). J Biol Chem (1999) ncbi
mouse monoclonal (LN27)
  • IHC-P; rabbit; 1:200; fig 1
  • WB; rabbit; 1:1000; fig 2
In order to study aluminum maltolate-induced neurofibrillary degeneration in rabbits, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on rabbit samples at 1:200 (fig 1) and in western blot on rabbit samples at 1:1000 (fig 2). Brain Res (1997) ncbi
mouse monoclonal (AMY-33)
  • IP; human; fig 3
In order to examine beta-amyloid formation and its inhibition, Invitrogen APP antibody (Zymed, AMY-33) was used in immunoprecipitation on human samples (fig 3). Proc Natl Acad Sci U S A (1996) ncbi
mouse monoclonal (LN27)
  • IHC-P; human; 1:200
In order to investigate markers of axonal injury, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples at 1:200. Acta Neuropathol (1994) ncbi
mouse monoclonal (LN27)
  • IHC-P; human; 1:200
In order to study 3B11 immunoreactivity in the human brain, Invitrogen APP antibody (Zymed, LN27) was used in immunohistochemistry - paraffin section on human samples at 1:200. Biochem J (1995) ncbi
EMD Millipore
rabbit polyclonal
  • ELISA; human
EMD Millipore APP antibody (Millipore, AB5737) was used in ELISA on human samples. J Nutr Biochem (2015) ncbi
rabbit polyclonal
  • WB; human
EMD Millipore APP antibody (Millipore, AB5352) was used in western blot on human samples. Neurobiol Aging (2015) ncbi
mouse monoclonal (mC99(70-80))
  • WB; human; 1:1000; fig 7
EMD Millipore APP antibody (Millipore, MABN380) was used in western blot on human samples at 1:1000 (fig 7). J Pineal Res (2015) ncbi
goat polyclonal
  • IC; mouse; 1:500
EMD Millipore APP antibody (Millipore, AB1593) was used in immunocytochemistry on mouse samples at 1:500. Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:600
EMD Millipore APP antibody (Millipore, AB9234) was used in western blot on mouse samples at 1:600. Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:1000
EMD Millipore APP antibody (EMD Millipore, AB9234) was used in immunohistochemistry on mouse samples at 1:1000. PLoS ONE (2015) ncbi
mouse monoclonal (2.F2.19B4)
  • WB; mouse; 1:5000
EMD Millipore APP antibody (Millipore, 2.F2.19B4) was used in western blot on mouse samples at 1:5000. Brain (2015) ncbi
mouse monoclonal (6C3)
  • IHC-Free; mouse; 1:200
EMD Millipore APP antibody (Millipore, 6C3) was used in immunohistochemistry - free floating section on mouse samples at 1:200. Brain (2015) ncbi
mouse monoclonal (WO2)
  • WB; mouse; 1:2000
In order to explore a nonpharmacological approach, repeated scanning ultrasound treatments, for removing Abeta and restoring memory function in a mouse model of Alzheimer's disease, EMD Millipore APP antibody (Millipore, WO-2) was used in western blot on mouse samples at 1:2000. Sci Transl Med (2015) ncbi
rabbit polyclonal
  • IHC-P; rat; 1:2000
EMD Millipore APP antibody (Chemicon, AB9234) was used in immunohistochemistry - paraffin section on rat samples at 1:2000. Fluids Barriers CNS (2015) ncbi
rabbit polyclonal
  • IHC-P; human
In order to validate the European Alzheimer's Disease Consortium Alzheimer's Disease Neuroimaging Initiative Center Harmonized Hippocampal Segmentation Protocol (HarP)., EMD Millipore APP antibody (EMD Millipore, AB5074 P) was used in immunohistochemistry - paraffin section on human samples. Alzheimers Dement (2015) ncbi
mouse monoclonal (22C11)
  • WB; human; fig 1b
  • IP; human; fig 1b
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, EMD Millipore APP antibody (Millipore, 22C11) was used in western blot on human samples (fig 1b) and in immunoprecipitation on human samples (fig 1b). EMBO Mol Med (2015) ncbi
mouse monoclonal (22C11)
  • WB; mouse
In order to determine the effects of running on the neuronal structure and function of the hippocampus and amygdala in APP/PS1 transgenic mice, EMD Millipore APP antibody (Chemicon, 22C11) was used in western blot on mouse samples. Neurobiol Learn Mem (2015) ncbi
mouse monoclonal (22C11)
  • IHC-P; human; 1:1000
  • WB; human; 1:1000
In order to examine the importance of iron in relation to amyloid-beta production within the retina, EMD Millipore APP antibody (Millipore, 22c11) was used in immunohistochemistry - paraffin section on human samples at 1:1000 and in western blot on human samples at 1:1000. Exp Eye Res (2014) ncbi
rabbit polyclonal
  • IC; mouse; 1:100
EMD Millipore APP antibody (Millipore, AB5078P) was used in immunocytochemistry on mouse samples at 1:100. Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • IC; mouse; 1:100
EMD Millipore APP antibody (Millipore, AB5074P) was used in immunocytochemistry on mouse samples at 1:100. Neurobiol Aging (2015) ncbi
mouse monoclonal (22C11)
  • IC; mouse; 1:100
EMD Millipore APP antibody (Millipore, 22C11) was used in immunocytochemistry on mouse samples at 1:100. Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • IHC-P; human; 1:1000
EMD Millipore APP antibody (Chemicon International, AB1510) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Am J Neurodegener Dis (2014) ncbi
mouse monoclonal (22C11)
  • WB; mouse; 1:2000
EMD Millipore APP antibody (Millipore, 22C11) was used in western blot on mouse samples at 1:2000. PLoS ONE (2014) ncbi
mouse monoclonal (22C11)
  • WB; hamsters
EMD Millipore APP antibody (Chemicon, 22C11) was used in western blot on hamsters samples. Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (4.1)
  • WB; mouse; 1:1000
EMD Millipore APP antibody (Chemicon, MAB5354) was used in western blot on mouse samples at 1:1000. Neurobiol Aging (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1 ug/ml
  • IC; mouse
In order to study the role of the amyloid core of the acrosomal matrix in sperm-zona pellucida interactions, EMD Millipore APP antibody (EMD Millipore, AB9234) was used in western blot on mouse samples at 1 ug/ml and in immunocytochemistry on mouse samples. Mol Cell Biol (2014) ncbi
mouse monoclonal (WO2)
  • IHC-Free; human; fig 1
In order to present data that suggests that pathological Abeta species induce changes in Tau that contribute to cognitive deficits correlating with synaptic deficits and hippocampal atrophy in an Alzheimer's disease model, EMD Millipore APP antibody (Millipore, WO2) was used in immunohistochemistry - free floating section on human samples (fig 1). FASEB J (2014) ncbi
rabbit polyclonal
  • IC; mouse; 1:25
In order to study the role of the Reelin pathway in Alzheimer's disease pathogenesis, EMD Millipore APP antibody (Chemicon, AB5076) was used in immunocytochemistry on mouse samples at 1:25. Nat Commun (2014) ncbi
rabbit polyclonal
  • IHC-P; mouse
  • WB; mouse
In order to study the beneficial effects of S100A9 deletion on memory and beta-amyloid pathology in a murine model of Alzheimer's disease, EMD Millipore APP antibody (Millipore, AB9234) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples. PLoS ONE (2014) ncbi
mouse monoclonal (22C11)
  • WB; human
In order to study the role of CREB in the mechanism by which neurotrypsin expression and agarin proteolysis is modulated by presenilins, EMD Millipore APP antibody (Millipore, 22C11) was used in western blot on human samples. J Biol Chem (2013) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, EMD Millipore APP antibody (Millipore, AB9234) was used in western blot on mouse samples at 1:1000. J Neurotrauma (2014) ncbi
rabbit polyclonal
  • IC; mouse
EMD Millipore APP antibody (Millipore, AB5352) was used in immunocytochemistry on mouse samples. Neurodegener Dis (2014) ncbi
mouse monoclonal (22C11)
  • IC; mouse
EMD Millipore APP antibody (Millipore, 22C11) was used in immunocytochemistry on mouse samples. Neurodegener Dis (2014) ncbi
rabbit polyclonal
  • IHC-Free; lowland gorilla; 1:100
In order to study the pathology of Alzheimer's disease in the western lowland Gorilla, EMD Millipore APP antibody (Millipore, AB5074P) was used in immunohistochemistry - free floating section on lowland gorilla samples at 1:100. J Comp Neurol (2013) ncbi
mouse monoclonal (22C11)
  • IP; human
  • WB; human
EMD Millipore APP antibody (Millipore, 22C11) was used in immunoprecipitation on human samples and in western blot on human samples. Neurobiol Aging (2012) ncbi
not indicated
  • WB; human
Calbiochem anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics.PLoS ONE (2009) ncbi
not indicated
  • WB; human
Chemicon anti-APP was used in 1:1,000 dilution to perform western blot in order to show that new BACE1 substrates were identified by quantitative proteomics.PLoS ONE (2009) ncbi
not indicated
  • IHC; human
Millipore/Chemicon anti-amyloid precursor protein antibody was used for western blot to elucidated the role of white matter tauopathy in frontotemporal lobar degeneration.J Neuropathol Exp Neurol (2008) ncbi
not indicated
  • WB; human
Chemicon monoclonal anti-Abeta (4GB) antibody was used in western blot in order to study the role of NGF or BDNF signaling in neuronal apoptotic deathProc Natl Acad Sci U S A (2008) ncbi
not indicated
  • WB; human
Chemicon monoclonal anti-APP (22C11) antibody was used in western blot in order to study the role of NGF or BDNF signaling in neuronal apoptotic deathProc Natl Acad Sci U S A (2008) ncbi
not indicated
  • WB; human
Chemicon International anti-sAPP beta antibody (APP-WT) and anti-total sAPP antibody (22C11) were used in human cells and in western blot to study the role for ubiquilin 1 in modulating amyloid precursor protein trafficking and Abeta secretion.J Biol Chem (2006) ncbi
not indicated
  • IC; human
  • IHC; human
CHEMICON International mouse anti Alzheimer precursor protein A4 antibody was used in immunohistochemistry and immunocytochemistry to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.J Cell Biol (2005) ncbi
not indicated
  • WB; human
  • IP; human
Chemicon 22C11 APP monoclonal antibody was used in western blot and immunoprecipitation to investigate the binding of the BRI2 to APP precursor protein.J Biol Chem (2005) ncbi
mouse monoclonal (22C11)
  • WB; human
Chemicon monoclonal anti-APP antibody was used in western blot to detect APP in CHO-APP695 Cells.Proc Natl Acad Sci U S A (2005) ncbi
mouse monoclonal (DE2)
  • IHC; human
Millipore mouse mAb APP beta-amyloid 1-16 was used to perform immunohistochemistry in order to study the role of serine protease HtrA1 in amyloid precursor protein processing.Proc Natl Acad Sci U S A (2005) ncbi
not indicated
  • WB; human
  • IP; human
Chemicon International monoclonal APP NTF (22C11) antibody and polyclonal APP CTF antibody was used in Western blot and immunoprecipitation to study the biological function of presenilin-1 maturation.J Biol Chem (2005) ncbi
not indicated
  • WB; human
Chemicon anti-APP monoclonal antibody was used in western blot to study Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell deathJ Biol Chem (2005) ncbi
Abcam
rabbit monoclonal (Y188)
  • WB; rat; 1:5000
In order to localize ADAM10 and BACE1 in synaptic vesicles, Abcam APP antibody (Abcam, ab32136) was used in western blot on rat samples at 1:5000. J Neurochem (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:200
Abcam APP antibody (Abcam, AB10148) was used in immunohistochemistry on mouse samples at 1:200. Front Neurosci (2015) ncbi
mouse monoclonal (BDI350)
  • WB; mouse
Abcam APP antibody (Abcam, ab20068) was used in western blot on mouse samples. J Inorg Biochem (2015) ncbi
rabbit monoclonal (Y188)
  • IHC; mouse; 1:1000
Abcam APP antibody (Abcam, ab32136) was used in immunohistochemistry on mouse samples at 1:1000. J Neuroimmunol (2015) ncbi
rabbit monoclonal (Y188)
  • IHC-P; mouse
  • IP; mouse
  • WB; mouse
Abcam APP antibody (Abcam, Y188) was used in immunohistochemistry - paraffin section on mouse samples, in immunoprecipitation on mouse samples, and in western blot on mouse samples. Front Cell Neurosci (2015) ncbi
rabbit monoclonal (Y188)
  • WB; mouse; 1:1000
In order to assess the effect of CD11b-positive (+) monocytes on Alzheimer's disease using a mouse model, Abcam APP antibody (Abcam, ab32136) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
Abcam APP antibody (Abcam, ab15272) was used in western blot on rat samples at 1:1000. Mol Neurobiol (2016) ncbi
rabbit polyclonal
  • IHC-P; rat; 1:200
  • WB; rat; 1:1000
Abcam APP antibody (Abcam, ab10148) was used in immunohistochemistry - paraffin section on rat samples at 1:200 and in western blot on rat samples at 1:1000. Mol Neurobiol (2016) ncbi
rabbit polyclonal
  • IHC-P; human; 1:200
In order to examine the importance of iron in relation to amyloid-beta production within the retina, Abcam APP antibody (Abcam, Ab2539) was used in immunohistochemistry - paraffin section on human samples at 1:200. Exp Eye Res (2014) ncbi
rabbit polyclonal
  • WB; rat
  • IHC; rat
  • IC; rat; 1:100
Abcam APP antibody (Abcam, ab10148) was used in western blot on rat samples, in immunohistochemistry on rat samples, and in immunocytochemistry on rat samples at 1:100. Toxicol Sci (2015) ncbi
rabbit polyclonal
  • IC; rat; 1:100
  • WB; rat; 1:1000
Abcam APP antibody (Abcam, ab15272) was used in immunocytochemistry on rat samples at 1:100 and in western blot on rat samples at 1:1000. Toxicol Sci (2015) ncbi
rabbit monoclonal (Y188)
  • IC; human
Abcam APP antibody (Abcam, Y188) was used in immunocytochemistry on human samples. J Biol Chem (2014) ncbi
rabbit monoclonal (Y188)
  • WB; mouse
Abcam APP antibody (Abcam, Y188) was used in western blot on mouse samples. J Neurosci (2014) ncbi
rabbit polyclonal
  • IHC-F; mouse; 1:50
Abcam APP antibody (Abcam, ab10148) was used in immunohistochemistry - frozen section on mouse samples at 1:50. J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • WB; human
  • WB; rat
  • IHC; human; 1:50
  • IHC; rat; 1:50
Abcam APP antibody (Abcam, ab10148) was used in western blot on human samples and on rat samples and in immunohistochemistry on human samples at 1:50 and on rat samples at 1:50. Bone (2014) ncbi
mouse monoclonal (DE2B4)
  • IHC-Free; mouse
Abcam APP antibody (Abcam, AB11132) was used in immunohistochemistry - free floating section on mouse samples. Brain Behav (2013) ncbi
rabbit polyclonal
  • IHC-P; human; 1:500
In order to study the potential involvement of prolyl oligopeptidase in neurodegenerative diseases by monitoring its colocalization with pathological proteins in Parkinson's and Alzheimer's diseases, Abcam APP antibody (Abcam, ab10148) was used in immunohistochemistry - paraffin section on human samples at 1:500. Neuroscience (2013) ncbi
rabbit polyclonal
  • IHC-P; rat; 1:100
Abcam APP antibody (Abcam, ab10148) was used in immunohistochemistry - paraffin section on rat samples at 1:100. Behav Brain Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (20.1)
  • WB; human
Santa Cruz Biotechnology APP antibody (Santa Cruz Biotechnology, sc-53822) was used in western blot on human samples. Cell Mol Life Sci (2016) ncbi
mouse monoclonal (DE2B4)
  • WB; human; 1:1000; fig 7
Santa Cruz Biotechnology APP antibody (Santa Cruz, DE2B4) was used in western blot on human samples at 1:1000 (fig 7). J Pineal Res (2015) ncbi
mouse monoclonal (DE2B4)
  • WB; human; 1:500
Santa Cruz Biotechnology APP antibody (Santa Cruz Biotechnology, DE2B4) was used in western blot on human samples at 1:500. J Pineal Res (2015) ncbi
mouse monoclonal (NAB228)
  • IHC-P; human; 1:500
In order to determine the expression of abnormal serine phosphorylation of insulin receptor substrate 1 in healthy and diseased human brains, Santa Cruz Biotechnology APP antibody (Santa Cruz, 3227) was used in immunohistochemistry - paraffin section on human samples at 1:500. Acta Neuropathol (2014) ncbi
AbD Serotec (Bio-Rad)
rabbit polyclonal
  • WB; human; 1:500
AbD Serotec (Bio-Rad) APP antibody (AbD Serotec, AHP665) was used in western blot on human samples at 1:500. J Alzheimers Dis (2013) ncbi
rabbit polyclonal
  • WB; rat; 1:500
AbD Serotec (Bio-Rad) APP antibody (Serotec, AHP538) was used in western blot on rat samples at 1:500. BMC Complement Altern Med (2012) ncbi
rabbit polyclonal
  • WB; rat; 1:1000
AbD Serotec (Bio-Rad) APP antibody (Serotec, AHP538) was used in western blot on rat samples at 1:1000. J Comp Neurol (2007) ncbi
Novus Biologicals
mouse monoclonal (MOAB-2)
  • IHC-Free; mouse; 1:2000
In order to use the APP/PS1 (APPSWE, PSEN1dE9) transgenic model of Alzheimer's disease to study the role of localized damage on disease progression, Novus Biologicals APP antibody (Novus Biologicals, NBP2-13075) was used in immunohistochemistry - free floating section on mouse samples at 1:2000. Exp Neurol (2015) ncbi
Immuno-Biological Laboratories
mouse monoclonal (6A1)
  • WB; human; fig 3b
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, Immuno-Biological Laboratories APP antibody (Immuno-Biological Laboratories, 10321) was used in western blot on human samples (fig 3b). EMBO Mol Med (2015) ncbi
Hycult Biotech
not indicated
  • WB; human
  • IHC; human
Covance anti-Amyloid beta monoclonal antibody (4G8, 1:200 dilution) was used to perform western blot and immunoprecipitation in order to clarify that amyloid beta is an antimicrobial peptide that may normally function in the innate immune system.PLoS ONE (2010) ncbi
Epitomics
not indicated
  • WB; human
  • IHC; human
Epitomics anti-APP antibody was used to perform immunohistochemistry and western blot in order to study the roles of the amyloid precursor protein in peripheral and central synaptogenesis. .J Neurosci (2009) ncbi
Sigma-Aldrich
rabbit polyclonal
  • WB; mouse; 1:10000
Sigma-Aldrich APP antibody (Sigma, A8717) was used in western blot on mouse samples at 1:10000. Neurobiol Aging (2015) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000
In order to assess the neuroprotective effect of quercetin administration in the triple transgenic Alzheimer's disease model mice, Sigma-Aldrich APP antibody (Sigma, A8717) was used in western blot on mouse samples at 1:1000. Neuropharmacology (2015) ncbi
rabbit polyclonal
  • ELISA; rat
Sigma-Aldrich APP antibody (Sigma Chemical, A1976) was used in ELISA on rat samples. Mol Neurobiol (2016) ncbi
rabbit polyclonal
  • WB; rat
Sigma-Aldrich APP antibody (Sigma Chemical, A8717) was used in western blot on rat samples. Mol Neurobiol (2016) ncbi
rabbit polyclonal
  • WB; human
  • IC; human
Sigma-Aldrich APP antibody (Sigma-Aldrich, A8717) was used in western blot on human samples and in immunocytochemistry on human samples. J Cell Physiol (2015) ncbi
rabbit polyclonal
  • WB; human; 1:4000
Sigma-Aldrich APP antibody (Sigma, A8717) was used in western blot on human samples at 1:4000. J Pineal Res (2015) ncbi
mouse monoclonal (BAM90.1)
  • IHC; mouse; 1:250
In order to investigate hypercholesterolemia at various stages of Alzheimer's disease, Sigma-Aldrich APP antibody (Sigma, A8978) was used in immunohistochemistry on mouse samples at 1:250. Mol Cell Neurosci (2014) ncbi
rabbit polyclonal
  • IC; human
Sigma-Aldrich APP antibody (Sigma, A8717) was used in immunocytochemistry on human samples. J Biol Chem (2014) ncbi
rabbit polyclonal
  • WB; human; 1:1000
Sigma-Aldrich APP antibody (Sigma, A8717) was used in western blot on human samples at 1:1000. Mol Brain (2014) ncbi
rabbit polyclonal
  • WB; human
In order to elucidate the mechanisms that regulate UCHL1 levels in Alzheimer's disease AD, Sigma-Aldrich APP antibody (SIGMA, A8717) was used in western blot on human samples. Neuroscience (2014) ncbi
rabbit polyclonal
  • WB; mouse; 1:1000; fig 3
In order to investigate the contribution of IL-12/23 to disease using SAMP8 mice, Sigma-Aldrich APP antibody (Sigma-Aldrich, A8717) was used in western blot on mouse samples at 1:1000 (fig 3). J Alzheimers Dis (2014) ncbi
mouse monoclonal (4G8)
  • IHC-F; mouse
In order to study the composition of pathological granules that appear in degenerative brain diseases, Sigma-Aldrich APP antibody (Sigma, A1349) was used in immunohistochemistry - frozen section on mouse samples. Age (Dordr) (2014) ncbi
not indicated
  • IHC; human
Sigma mouse anti-human Abeta antibody (clone 4G8) was used in immunohistochemistry to study the role for lactadherin in Alzheimer s disease in sections from human.Am J Pathol (2007) ncbi
not indicated
  • WB; human
Sigma-Aldrich polyclonal anti-APP C-terminal antibody (1/4,000) was used in western blot to detect the early phenotypic modifications of Alzheimer's disease (AD) models.J Neurosci Res (2007) ncbi
not indicated
  • WB; human
  • IP; human
Sigma anti-APP-CTF antibody (A8717) was used in human cells and in western blot, immunoprecipitation to study the role for ubiquilin 1 in modulating amyloid precursor protein trafficking and Abeta secretion.J Biol Chem (2006) ncbi
not indicated
  • IHC; human
Sigma rabbit polyclonal anti-Amyloid Peptide beta antibody (A1976) was used in tissue sections from human brain and in immunohistochemistry to study the expression of serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients.BMC Neurosci (2006) ncbi
not indicated
  • WB; human
Sigma rabbit polyclonal anti-APP antibody (alphaAPP/C) was used in western blot to study the interaction of AICD with FE65 and 14-3-3 modulate FE65-dependent gene transactivation.J Biol Chem (2005) ncbi
not indicated
  • IHC; human
Sigma-Aldrich anti-dynamin 1 antibody was used in immunohistochemistry in order to investigate the molecular mechanism of beta-amyloid induced significant decrease of dynamin1.J Biol Chem (2005) ncbi
Cell Signaling Technology
rabbit monoclonal (D54D2)
  • WB; mouse; 1:1000
Cell Signaling Technology APP antibody (Cell Signaling, 8243) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2015) ncbi
rabbit monoclonal (D54D2)
  • WB; human; 1:200; fig 7
In order to determine the role of PICALM in Abeta transcytosis across the blood brain barrier, Cell Signaling Technology APP antibody (Cell Signaling Technology, 8243) was used in western blot on human samples at 1:200 (fig 7). Nat Neurosci (2015) ncbi
rabbit polyclonal
  • IHC; mouse; 1:250
In order to study epileptiform activity mouse models of Alzheimer's disease, Cell Signaling Technology APP antibody (Cell Signaling Technology, 2454) was used in immunohistochemistry on mouse samples at 1:250. Alzheimers Res Ther (2015) ncbi
rabbit polyclonal
  • IC; mouse
  • WB; mouse; 1:250
In order to investigate the effect of amyloid precursor protein on Nav1.6 sodium channel cell surface expression, Cell Signaling Technology APP antibody (Cell Signaling Technology, 3823) was used in immunocytochemistry on mouse samples and in western blot on mouse samples at 1:250. J Biol Chem (2015) ncbi
rabbit monoclonal (D54D2)
  • WB; human; 1:1000
In order to assess the effect of carnosic acid on apoptosis induced by Abeta42 or Abeta43 in human neuroblastoma cells, Cell Signaling Technology APP antibody (Cell Signaling, #8243) was used in western blot on human samples at 1:1000. Neurosci Res (2015) ncbi
rabbit monoclonal (D2A6H)
  • ELISA; human
  • WB; human
In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, Cell Signaling Technology APP antibody (Cell Signaling, 12356BF) was used in ELISA on human samples and in western blot on human samples. Int J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • WB; mouse
Cell Signaling Technology APP antibody (Cell Signalin, 2452S) was used in western blot on mouse samples. Cell Mol Neurobiol (2014) ncbi
not indicated
  • WB; human
Cell Signaling Technology rabbit anti-APP antibody was used in western blot to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.J Cell Biol (2005) ncbi
Dako
mouse monoclonal (6F/3D)
  • IHC-P; human; 1:100
In order to present data from the first donated Lothian Birth Cohort of 1936 and compare it with other aged and diseased samples, Dako APP antibody (Dako, M087201-2) was used in immunohistochemistry - paraffin section on human samples at 1:100. Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (6F/3D)
  • IHC-P; human; 1:50
In order to study neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease in mice, Dako APP antibody (Dako, 6 F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Neuropathol Exp Neurol (2015) ncbi
mouse monoclonal (6F/3D)
  • IHC-P; human; 1:500
In order to evaluate the role of DNA content in Lewy body diseases, Dako APP antibody (Dako, M0872) was used in immunohistochemistry - paraffin section on human samples at 1:500. Neurobiol Aging (2015) ncbi
mouse monoclonal (6F/3D)
  • IHC-Free; mouse; 1:100
In order to investigate the abnormalites in hippocampal energy metabolism in the pathogenesis of Alzheimer disease, Dako APP antibody (DakoCytomation, 6F/3D) was used in immunohistochemistry - free floating section on mouse samples at 1:100. Biochim Biophys Acta (2014) ncbi
mouse monoclonal (6F/3D)
  • IHC; human; 1:100
Dako APP antibody (Dako, M0872) was used in immunohistochemistry on human samples at 1:100. Neurobiol Aging (2014) ncbi
mouse monoclonal (6F/3D)
  • IHC-P; human; 1:200
Dako APP antibody (DAKO, 6F/3D) was used in immunohistochemistry - paraffin section on human samples at 1:200. Glia (2013) ncbi
mouse monoclonal (6F/3D)
  • IHC-Free; human; 1:50
Dako APP antibody (Dako, 6F/3D) was used in immunohistochemistry - free floating section on human samples at 1:50. Brain Res (2001) ncbi
AnaSpec
not indicatedAnaspec scrambled Abeta1-42 peptide was used to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands.Proc Natl Acad Sci U S A (2009) ncbi
American Peptide Company
not indicatedAmerican Peptide Company Abeta 1-42 was used to perform Abeta oligomer preparation in order to show that yeast could be used to model Abeta toxicity for potential modifier screen.Science (2011) ncbi
not indicatedAmerican Peptides synthetic Abeta1-42 peptide was used to test the hypothesis that insulin signaling provides a physiological defense mechanism against the synaptotoxicity of Abeta-derived diffusible ligands.Proc Natl Acad Sci U S A (2009) ncbi
Biocat
not indicated
  • IHC; human
BioCat anti-A beta antibody was used to perform immunohistochemistry in order to show that the existence of peptides targeted by NEP can improve learning and memory in aged mice.PLoS ONE (2009) ncbi
Peptide Institute
not indicatedPeptide Institute humanAbeta1-42 peptide was used as to determine the stress-inducing stimuli effects on AQP1 expression in human astrocytes in order to investigate the association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains.Acta Neuropathol (2008) ncbi
not indicatedPeptide Institute humanAbeta1-40 peptide was used as to determine its stress-inducing effect on AQP1 expression in human astrocytes in order to investigate the association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains.Acta Neuropathol (2008) ncbi
others
not indicated
  • ELISA; human
Agrisera AB polyclonal rabbit anti-Abeta was used in 1:2,000 to perform ELISA in order to show that yeast could be used to model Abeta toxicity for potential modifier screen.Science (2011) ncbi
not indicated
  • IHC; human
Signet Labs A beta peptide (6E10, 1 : 400) antibody was used in immunohistochemistry to study a novel progranulin mutation associated with variable clinical presentation and tau, TDP43, and alpha-synuclein pathologyBrain (2007) ncbi
not indicated
  • ELISA; human
Genetics Company Abeta40-specific ELISA was used to perform ELISA in order to study the role of serine protease HtrA1 in amyloid precursor protein processing.Proc Natl Acad Sci U S A (2005) ncbi
not indicated
  • IC; human
Elan Pharmaceuticals monoclonal antibody against Abeta- (1 5) was used in immunocytochemistry to study hypoxic augmentation of Ca2+ channel currentsJ Biol Chem (2005) ncbi
Articles Reviewed
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