This is a review about APC, based on 10 published articles (read how Labome selects the articles), using APC antibody in experiments. It is aimed to help Labome visitors find the most suited APC antibody.
APC synonym: BTPS2; DP2; DP2.5; DP3; PPP1R46; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli protein; deleted in polyposis 2.5; protein phosphatase 1, regulatory subunit 46

  • Calbiochem anti-APC was used to perform immunocytochemistry in order to show that MRP protein plays an important role in adherens junction formation and tumorigenesisncbi, more , figure 1
  • Figure 1
    APC antibody immunocytochemistry EMD Millipore
    APC antibody immunocytochemistry EMD Millipore
    EpRas, C1, E13 or E14 cells were stained with primary antibodies specific to either E-cadherin (Becton Dickinson), APC (Calbiochem) or beta-catenin (Becton Dickinson)
    Alexander E Finlayson et al. (2009). "A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis".PMID 19924305
  • Oncogene mouse anti-APC antibody was used in immunocytochemistry to study the effect of truncating APC mutations on proliferation, spindle checkpoint control, survival and chromosome stabilityncbi, more
  • Oncogene Research Products anti-APC mouse monoclonal IgG (1:100) (Ab-1) was used in western blot to study the diversion of nuclear beta-Catenin from TCFncbi, more
  • Calbiochem mouse monoclonal anti-APC antibody (OP-44) was used in western blot to study the regulation of casein kinase 2 activity by adenomatous polyposis coli proteinncbi, more
Santa Cruz BiotechnologySanta Cruz Biotechnology APC product
  • Santa Cruz Biotechnology rabbit polyclonal antibody to the N-terminus of APC antibody was used for western blot in order to investigate the role Wnt/beta-catenin pathway in the regulation of both physiological and pathophysiological conditions.ncbi, more
  • Santa Cruz Biotechnology rabbit anti-human-APC antibody(N-15 1:200, C-20 1:20) was used to perform western blot and immunohistochemistry in order to study promoter methylation and protein expression of APC in HCC.ncbi, more
  • Santa Cruz anti-APC-C polyclonal (C-20) antibody was used in western blot and immunoprecipitation to study IQGAP1 and APC interaction during cell polarization and migrationncbi, more
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    Santa Cruz Biotechnology5APC antibody
    EMD Millipore2APC antibody
    Table 1. APC antibody western blot.
  • Santa Cruz Biotechnology anti-APC rabbit polyclonal IgG (1:50) (C-20) was used in immunoprecipitation to study the diversion of nuclear beta-Catenin from TCFncbi, more
  • Santa Cruz Biotechnology anti-APC monoclonal antibody was used in immunocytochemistry and anti-APC polyclonal antibody (APC (C-20) was used in western blot to study Adenomatous Polyposis Coli down-regulation by the ubiquitin-proteasome pathwayncbi, more
  • Santa Cruz Biotechnology rabbit polyclonal anti-APC COOH terminus (C-20) was used in western blot to detect APC in human HCT116 cells, rabbit polyclonal anti APC NH2 terminus (N-15) antibody was used in immunocytochemistry to determine where the membrane-associated fraction of APC localizes in human HCT116 cells, and in immunohistochemistry to determine the subcellular localization of APC in mouse colon.ncbi, more
  • Pharmingen anti-APC antibody was used to perform western blot in order to study the dependency on oxidative phosphorylation during transformation of human mesenchymal stem cells.ncbi, more
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EMD Millipore2APC antibody
Santa Cruz Biotechnology2APC antibody
Table 2. APC antibody immunocytochemistry.
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Santa Cruz Biotechnology2APC antibody
Table 3. APC antibody immunoprecipitation.
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Santa Cruz Biotechnology2APC antibody
Table 4. APC antibody immunohistochemistry.
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BD Biosciences1APC antibody
Table 5. APC antibody flow cytometry.
Articles Reviewed
  1. Michael Buchert et al. (2010). "Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo".PMID 20084116
  2. Alexander E Finlayson et al. (2009). "A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis".PMID 19924305
  3. Antal Csepregi et al. (2008). "APC promoter methylation and protein expression in hepatocellular carcinoma".PMID 17973119
  4. Juan M Funes et al. (2007). "Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production".PMID 17384149
  5. Takashi Watanabe et al. (2004). "Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration".PMID 15572129
  6. Anthony Tighe et al. (2004). "Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability".PMID 15561772
  7. Fumihiko Hamada et al. (2004). "The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF".PMID 15525529
  8. Jongkyu Choi et al. (2004). "Adenomatous polyposis coli is down-regulated by the ubiquitin-proteasome pathway in a process facilitated by Axin".PMID 15355978
  9. Miwako Kato Homma et al. (2002). "Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein".PMID 11972058
  10. A Reinacher-Schick et al. (2001). "Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells".PMID 11157977