This is a review about ABCB1, based on 33 published articles (read how Labome selects the articles), using ABCB1 antibody in all methods. It is aimed to help Labome visitors find the most suited ABCB1 antibody.
ABCB1 synonym: ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance

Santa Cruz Biotechnology
mouse monoclonal (G-1)
  • WB; human; 1:1000; fig 2
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz Biotechnology, sc-13131) was used in western blot on human samples at 1:1000 (fig 2). Cancer Gene Ther (2015) ncbi
mouse monoclonal (G-1)
  • WB; human
In order to study the role of Wnt5A signaling in cancer drug resistance, Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz Biotechnology, sc-13131) was used in western blot on human samples. Oncotarget (2014) ncbi
mouse monoclonal (D-11)
  • WB; human; fig 4
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz, sc-55510) was used in western blot on human samples (fig 4). Oncol Rep (2015) ncbi
rabbit polyclonal (H-241)
  • WB; human
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz, sc-8313) was used in western blot on human samples. Lab Chip (2014) ncbi
mouse monoclonal (D-11)
  • IC; human; 1:500
  • WB; human; 1:100
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz, sc-55510) was used in immunocytochemistry on human samples at 1:500 and in western blot on human samples at 1:100. Mol Pharm (2014) ncbi
mouse monoclonal (G-1)
  • WB; human
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz, sc-13131) was used in western blot on human samples. Anat Rec (Hoboken) (2014) ncbi
rabbit polyclonal (H-241)
  • IP; human
In order to investigate the relationship between PP5/PPP2R3C and P-gp, Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz Biotechnology, H-241) was used in immunoprecipitation on human samples. Cancer Lett (2014) ncbi
rabbit polyclonal (H-241)
  • IHC-F; mouse
Santa Cruz Biotechnology ABCB1 antibody (Santa Cruz Biotechnology, sc-8313) was used in immunohistochemistry - frozen section on mouse samples. BMC Gastroenterol (2013) ncbi
not indicated
  • WB; human
Santa Cruz Biotechnology MDR1 antibody (1:500) was used to perform western blot in order to clarify that YB-1, GST, ABCB5, and ERK3 could be potential targets against drug resistant breast cancer cells.BMC Cancer (2010) ncbi
not indicated
  • IHC; human
Santa Cruz rabbit anti-human Dkk-4 antibody was used to perform immunohistochemistry in order to investigate the expression alteration of dickkopfs (Dkks) and kremen2 (Krm2) in gastrointestinal cancer.World J Gastroenterol (2008) ncbi
EMD Millipore
mouse monoclonal (UIC2)
  • IC; human
EMD Millipore ABCB1 antibody (Millipore, UIC2) was used in immunocytochemistry on human samples. Cell Oncol (Dordr) (2014) ncbi
mouse monoclonal (JSB-1)
  • IHC; human; 1:200
EMD Millipore ABCB1 antibody (Millipore, MAB4120) was used in immunohistochemistry on human samples at 1:200. PLoS ONE (2014) ncbi
mouse monoclonal (MM4.17)
  • FC; human
EMD Millipore ABCB1 antibody (Millipore, MAB4162) was used in flow cytometry on human samples. Sci Rep (2014) ncbi
mouse monoclonal (5A12.2)
  • WB; human; 1:5000
EMD Millipore ABCB1 antibody (EMD Millipore, 5A12.2) was used in western blot on human samples at 1:5000. Placenta (2014) ncbi
mouse monoclonal (JSB-1)
  • IHC-P; human; 1:20
  • WB; human; 1:50
EMD Millipore ABCB1 antibody (Chemicon, mab4120) was used in immunohistochemistry - paraffin section on human samples at 1:20 and in western blot on human samples at 1:50. PLoS ONE (2013) ncbi
not indicated
  • WB; human
Chemicon mouse monoclonal MDR1 antibody was used to carry out western blot analysis in order to investigate the transcriptional regulatory function of APE1 and its association with drug resistance in tumor cells.Mol Cell Biol (2008) ncbi
not indicated
  • WB; human
Calbiochem mouse monoclonal anti-MDR1 antibody (C219, which recognizes an internal epitope of human MDR1) was used in western blot to study dynamic regulation of MDR1 transport capacity.Br J Pharmacol (2008) ncbi
not indicated
  • IC; human
Chemicon mouse anti-MDR1 antibody (UIC2, which recognizes an extracellular conformational epitope of MDR1) was used to amplify DNA of primers for CAR in real-time quantitative PCR to study dynamic regulation of MDR1 transport capacity.Br J Pharmacol (2008) ncbi
not indicated
  • WB; human
Calbiochem anti-ABCB1 antibody was used to perform western blot in order to find out the genes involved with cisplatin resistance in human oral squamous cell carcinoma cell line.BMC Cancer (2006) ncbi
Invitrogen
mouse monoclonal (C219)
  • WB; pig; 1:1000
Invitrogen ABCB1 antibody (Zymed Laboratories, C219) was used in western blot on pig samples at 1:1000. Biopharm Drug Dispos (2015) ncbi
mouse monoclonal (C494)
  • IHC-P; human
In order to use molecular profiling to assess expression of biomarkers of operable gastric adenocarcinoma being treated with epirubicin, cisplatin, and 5-fluorouracil, Invitrogen ABCB1 antibody (Invitrogen, C494) was used in immunohistochemistry - paraffin section on human samples. J Surg Oncol (2014) ncbi
mouse monoclonal (C219)
  • WB; human; 1:20
In order to study cord blood as a source of circulating endothelial progenitor cells that can be directed towards specialized endothelial phenotypes, Invitrogen ABCB1 antibody (Thermoscientific, MA1-26528) was used in western blot on human samples at 1:20. PLoS ONE (2014) ncbi
mouse monoclonal (C219)
  • WB; human
In order to investigate the relationship between PP5/PPP2R3C and P-gp, Invitrogen ABCB1 antibody (Invitrogen, C219) was used in western blot on human samples. Cancer Lett (2014) ncbi
Abcam
mouse monoclonal (JSB-1)
  • IHC-F; rat; 1:200
Abcam ABCB1 antibody (Abcam Lab, ab3366) was used in immunohistochemistry - frozen section on rat samples at 1:200. Pharmacol Rep (2014) ncbi
mouse monoclonal (JSB-1)
  • WB; human
Abcam ABCB1 antibody (Abcam, ab3366) was used in western blot on human samples. Mol Biol Rep (2013) ncbi
mouse monoclonal (JSB-1)
  • IHC-P; human; 1:40
  • WB; human; 1:200
Abcam ABCB1 antibody (Abcam, ab3366) was used in immunohistochemistry - paraffin section on human samples at 1:40 and in western blot on human samples at 1:200. Oncol Lett (2013) ncbi
LifeSpan Biosciences
rabbit polyclonal
  • WB; human; 1:200
In order to elucidate the contribution of microRNAs in resistance to BRAF inhibitor treatment, LifeSpan Biosciences ABCB1 antibody (LifeSpan Biosciences, LS-B1448) was used in western blot on human samples at 1:200. Pigment Cell Melanoma Res (2015) ncbi
rabbit polyclonal
  • WB; human; 1:200
LifeSpan Biosciences ABCB1 antibody (LifeSpan, LS-B1448;) was used in western blot on human samples at 1:200. Am J Pathol (2012) ncbi
OriGene
mouse monoclonal (Clone OTI2F7)
  • WB; human
OriGene ABCB1 antibody (OriGene, TA801056) was used in western blot on human samples. Mol Cancer Ther (2015) ncbi
GeneTex
rabbit polyclonal
  • WB; human; 1:500
GeneTex ABCB1 antibody (GeneTex, GTX108370) was used in western blot on human samples at 1:500. Mol Med Rep (2015) ncbi
BioLegend
mouse monoclonal (UIC2)
  • FC; human
BioLegend ABCB1 antibody (BioLegend, UIC2) was used in flow cytometry on human samples. Eur J Immunol (2014) ncbi
Enzo Life Sciences
not indicated
  • WB; human
ALEXIS anti-ABCB1 antibody was used in western blot in order to study the biology and function of methylation-controlled J protein (MCJ).Mol Cell Biol (2007) ncbi
Sigma-Aldrich
mouse monoclonal (F4)
  • IHC; human
  • WB; human
Sigma-Aldrich ABCB1 antibody (Sigma-Aldrich, P7965) was used in immunohistochemistry on human samples and in western blot on human samples. J Biol Chem (2015) ncbi
not indicated
  • WB; human
  • IHC; human
Sigma-Aldrich MDR1 antibody was used in western blot and immunohistochemistry to assess the effect of grapefruit juice consumption on OATP1A2 expression relative to cytochrome P450 3A4 and MDR1.Clin Pharmacol Ther (2007) ncbi
BD Biosciences
mouse monoclonal (17F9)
  • IC; human; 1:100
BD Biosciences ABCB1 antibody (BD Biosciences, 557002) was used in immunocytochemistry on human samples at 1:100. J Biol Chem (2015) ncbi
others
not indicated
  • WB; human
  • IP; human
Centocor anti-P-glycoprotein (P-gp) antibody C219 was used in western blot and immunoprecipitation to study inhibition of multidrug resistance 1 P-glycoprotein phosphorylationJ Biol Chem (2005) ncbi
Articles Reviewed
  1. T H Hung et al. (2015). "Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines".PMID 25908454
  2. Shujing Liu et al. (2015). "miR-200c/Bmi1 axis and epithelial-mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment".PMID 25903073
  3. Weipeng Zhang et al. (2015). "Paclitaxel resistance in MCF-7/PTX cells is reversed by paeonol through suppression of the SET/phosphatidylinositol 3-kinase/Akt pathway".PMID 25760096
  4. Patric J Jansson et al. (2015). "Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidrug resistance by a novel mechanism involving the hijacking of lysosomal P-glycoprotein (Pgp)".PMID 25720491
  5. Frank Loganzo et al. (2015). "Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments".PMID 25646013
  6. Ibrahim Hasibu et al. (2015). "The guinea-pig expresses functional CYP2C and P-glycoprotein: further validation of its usefulness in drug biotransformation/transport studies".PMID 25472529
  7. Silvana Alvariza et al. (2014). "Chronic administration of phenytoin induces efflux transporter overexpression in rats".PMID 25443719
  8. Marzena Szwed et al. (2014). "Relationship between therapeutic efficacy of doxorubicin-transferrin conjugate and expression of P-glycoprotein in chronic erythromyeloblastoid leukemia cells sensitive and resistant to doxorubicin".PMID 25410120
  9. Tsai Hsien Hung et al. (2014). "Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway".PMID 25401518
  10. Congfei Wang et al. (2015). "Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression".PMID 25394408
  11. Robert F Kudernatsch et al. (2014). "Human bone marrow contains a subset of quiescent early memory CD8(+) T cells characterized by high CD127 expression and efflux capacity".PMID 25231631
  12. Julio Finalet Ferreiro et al. (2014). "Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma".PMID 25057852
  13. John T Miura et al. (2014). "Molecular profiling in gastric cancer: examining potential targets for chemotherapy".PMID 24844210
  14. Masahiro Yasunaga et al. (2014). "Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer".PMID 24781822
  15. R Booth et al. (2014). "A multiple-channel, multiple-assay platform for characterization of full-range shear stress effects on vascular endothelial cells".PMID 24718713
  16. M Javam et al. (2014). "Effect of oxygen on multidrug resistance in term human placenta".PMID 24685282
  17. Johanna J Salomon et al. (2014). "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier".PMID 24524365
  18. Julie Boyer-Di Ponio et al. (2014). "Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes".PMID 24392113
  19. Xuebing Liu et al. (2014). "Reversing effect of sorcin in the drug resistance of human nasopharyngeal carcinoma".PMID 24376145
  20. Kazuhiro Katayama et al. (2014). "Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function".PMID 24333728
  21. Wen jing Li et al. (2013). "Systematic expression analysis of genes related to multidrug-resistance in isogenic docetaxel- and adriamycin-resistant breast cancer cell lines".PMID 24078162
  22. Jin Xie et al. (2013). "Expression and significance of hypoxia-inducible factor-1α and MDR1/P-glycoprotein in laryngeal carcinoma tissue and hypoxic Hep-2 cells".PMID 23946810
  23. Shinji Ito et al. (2013). "Cholestasis induces reversible accumulation of periplakin in mouse liver".PMID 23849208
  24. Susanna J E Veringa et al. (2013). "In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma".PMID 23637844
  25. Shujing Liu et al. (2012). "miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1".PMID 22982443
  26. Ji Yeon Yang et al. (2010). "p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance".PMID 20649952
  27. Ranajoy Chattopadhyay et al. (2008). "Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1".PMID 18809583
  28. Tadateru Maehata et al. (2008). "Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer".PMID 18461655
  29. I S Haslam et al. (2008). "Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells".PMID 18332862
  30. Ketki M Hatle et al. (2007). "Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression".PMID 17283040
  31. H Glaeser et al. (2007). "Intestinal drug transporter expression and the impact of grapefruit juice in humans".PMID 17215845
  32. Ping Zhang et al. (2006). "Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line".PMID 16978399
  33. Maocheng Zhan et al. (2005). "Transcriptional repression of protein kinase Calpha via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation".PMID 15563462