| Articles Reviewed |
| 1: | Caterina Nardella et al. Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. 2008 |
| 2: | Fabián Arenas et al. Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. 2008 |
| 3: | Young Kwang Chae et al. Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML). 2008 |
| 4: | Yanlin Yu et al. The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis. 2006 |
| 5: | Noriyuki Uemura et al. TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. 2006 |
| 6: | Jie Zhao et al. IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. 2006 |
| 7: | Hui Wang et al. Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer. 2006 |
| 8: | Bryan D Griffin et al. Persistent interleukin-1beta signaling causes long term activation of NFkappaB in a promoter-specific manner in human glial cells. 2006 |
| 9: | Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006 |
| 10: | Anja Persson et al. A human protein atlas based on antibody proteomics. 2006 |
| 11: | Soon-Young Choi et al. Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells. 2006 |
| 12: | Annett Hahn-Windgassen et al. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity. 2005 |
| 13: | Hu Xu et al. Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells. 2005 |
| 14: | Christopher C Valley et al. Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus. 2005 |
| 15: | Tomoya S Kitajima et al. Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. 2005 |
| 16: | Charles E Ducker et al. Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. 2005 |
| 17: | Andrew V Samuelson et al. p400 is required for E1A to promote apoptosis. 2005 |
| 18: | Shravanti Rampalli et al. Tumor suppressor SMAR1 mediates cyclin D1 repression by recruitment of the SIN3/histone deacetylase 1 complex. 2005 |
| 19: | Xinbo Liao et al. Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer. 2005 |
| 20: | Kabsun Kim et al. Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. 2005 |
| 21: | Jean M Camden et al. P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing. 2005 |
| 22: | Cheng Zhang et al. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. 2005 |
| 23: | Sima Salahshor et al. Differential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis. 2005 |
| 24: | Kohsuke Kanekura et al. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. 2005 |
| 25: | Scott K Kuwada et al. Integrin alpha5/beta1 expression mediates HER-2 down-regulation in colon cancer cells. 2005 |
| 26: | Sheng Cao et al. KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. 2005 |
| 27: | Nikos Tapinos et al. Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli. 2005 |
| 28: | Laura Lynch et al. Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells. 2005 |
| 29: | Zsuzsanna Orbán-Németh et al. Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family. 2005 |
| 30: | Laura V Gonzalez Bosc et al. Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer. 2005 |
| 31: | Rachana Agarwal et al. Phosphorylation of claudin-3 at threonine 192 by cAMP-dependent protein kinase regulates tight junction barrier function in ovarian cancer cells. 2005 |
| 32: | Manabu Fujita et al. Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. 2005 |
| 33: | Juan Wang et al. Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway. 2005 |
| 34: | Karim Kaabeche et al. Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation. 2005 |
| 35: | Sang-Gu Hwang et al. Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin. 2005 |
| 36: | Andrew B West et al. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. 2005 |
| 37: | Kiven Erique Lukong et al. Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. 2005 |
| 38: | Bysani Chandrasekar et al. Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes. 2005 |
| 39: | CĂ©line Charvet et al. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. 2005 |
| 40: | An-Sheng Zhang et al. Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells. 2005 |
| 41: | Manish K Tripathi et al. Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells. 2005 |
| 42: | Kristi L Williams et al. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. 2005 |
| 43: | Mark W Jackson et al. p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2. 2005 |
| 44: | Yun Li et al. Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling. 2005 |
| 45: | Jing-Xu Zhu et al. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. 2005 |
| 46: | Bernard Dublet et al. Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site. 2005 |
| 47: | N A C S Wong et al. CDX1 is an important molecular mediator of Barrett's metaplasia. 2005 |
| 48: | Sophie Bonnal et al. Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA. 2005 |
| 49: | Lakita G Cavin et al. Transforming growth factor-alpha inhibits the intrinsic pathway of c-Myc-induced apoptosis through activation of nuclear factor-kappaB in murine hepatocellular carcinomas. 2005 |
| 50: | Jianmin Zhang et al. Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages. 2005 |
| 51: | Jing Li et al. Myristoylated alanine-rich C kinase substrate-mediated neurotensin release via protein kinase C-delta downstream of the Rho/ROK pathway. 2005 |
| 52: | Alessandra Alberghini et al. Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells. 2005 |
| 53: | James G Burchfield et al. Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta. 2004 |
| 54: | Brian A Pierchala et al. Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways. 2004 |
| 55: | Stephan Kiessling et al. Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells. 2004 |
| 56: | Jinhu Yin et al. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. 2004 |
| 57: | Michael J Piatelli et al. Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells. 2004 |
| 58: | Soheil Naderi et al. cAMP-induced degradation of cyclin D3 through association with GSK-3beta. 2004 |
| 59: | Irene M Ward et al. UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress. 2004 |
| 60: | Costanza Emanueli et al. Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer. 2004 |
| 61: | Jun Zhang et al. Cystatin m: a novel candidate tumor suppressor gene for breast cancer. 2004 |
| 62: | Silvestre Vicent et al. Mitogen-activated protein kinase phosphatase-1 is overexpressed in non-small cell lung cancer and is an independent predictor of outcome in patients. 2004 |
| 63: | Ajoy K Samanta et al. Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB. 2004 |
| 64: | Yun Dai et al. A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2. 2004 |
| 65: | Lynne Cassimeris et al. TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. 2004 |
| 66: | Jules Lin et al. Melanoma-associated antigens in esophageal adenocarcinoma: identification of novel MAGE-A10 splice variants. 2004 |
| 67: | Gareth R John et al. Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. 2004 |
| 68: | Renaud Dentin et al. Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. 2004 |
| 69: | Aitor G Granja et al. The viral protein A238L inhibits cyclooxygenase-2 expression through a nuclear factor of activated T cell-dependent transactivation pathway. 2004 |
| 70: | Khandaker N Anwar et al. RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65. 2004 |
| 71: | Pedro A Ruiz et al. 15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity. 2004 |
| 72: | Alberto Ballestrero et al. Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 2004 |
| 73: | Eisuke Itakura et al. Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage. 2004 |
| 74: | Md Ruhul Abid et al. Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB. 2004 |
| 75: | Jean-Martin Beaulieu et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. 2004 |
| 76: | Hiroshi Nishihara et al. Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2. 2003 |
| 77: | Pierre-François Cartron et al. Nonredundant role of Bax and Bak in Bid-mediated apoptosis. 2003 |
| 78: | Weidong Wu et al. Zinc-induced PTEN protein degradation through the proteasome pathway in human airway epithelial cells. 2003 |
| 79: | Xiaoyan Jiang et al. Evidence for a positive role of SHIP in the BCR-ABL-mediated transformation of primitive murine hematopoietic cells and in human chronic myeloid leukemia. 2003 |
| 80: | Zubin Master et al. Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization. 2003 |
| 81: | Chengjiang Gao et al. Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. 2003 |
| 82: | Asha L Bhakar et al. Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. 2003 |
| 83: | Audrey Robinson-White et al. Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2. 2003 |
| 84: | Fuminori Umenishi et al. Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene. 2003 |
| 85: | Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 86: | Dirk Haller et al. Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. 2003 |
| 87: | Gary S Goldberg et al. Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells. 2003 |
| 88: | Atsushi Iwata et al. Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies. 2003 |
| 89: | Maoxiang Li et al. The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation. 2003 |
| 90: | Tiho Miralem et al. Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus. 2003 |
| 91: | Atsushi Saito et al. Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway. 2003 |
| 92: | Chih-Cheng Yang et al. Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells. 2003 |
| 93: | Jonathan P Aumais et al. Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. 2003 |
| 94: | Kenji Hata et al. Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis. 2003 |
| 95: | Stefanie Galbán et al. von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays. 2003 |
| 96: | Anne M Comi et al. Increased fibronectin expression in sturge-weber syndrome fibroblasts and brain tissue. 2003 |
| 97: | Philippe Garnier et al. Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1. 2003 |
| 98: | Roberto R Rosato et al. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. 2003 |
| 99: | Stefanie Galbán et al. Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. 2003 |
| 100: | Arlette B Werner et al. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax. 2002 |
| 101: | Tadashi Yoshii et al. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. 2002 |
| 102: | Jennifer A Benanti et al. Induction of extracellular matrix-remodeling genes by the senescence-associated protein APA-1. 2002 |
| 103: | Denise C Hocking et al. A cryptic fragment from fibronectin's III1 module localizes to lipid rafts and stimulates cell growth and contractility. 2002 |
| 104: | Eun Ran Suh et al. DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines. 2002 |
| 105: | M Torcia et al. Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release. 2001 |
| 106: | C Guégan et al. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. 2001 |
| 107: | S Nakamura et al. Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination. 2000 |