AKT1 antibody | antibody review based on formal publications
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| This is a review about AKT1 antibodies, based on 297 published articles using AKT1 antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help Labome/ExactAntigen visitors find the most suited AKT1 antibody. |
Cell Signaling TechnologyCell Signaling Technology AKT1 products | |
| wb | Cell Signaling anti-phospho-Akt and anti-total-Akt antibodies were used in western blot to study the role of Pink1 in combating cell death. to the paper |
| wb | Cell Signaling Technology rabbit anti-Akt and anti-phospho-Akt antibodies were used in western blot to study the role for IGF-1 in the growth of myeloma cell lines and the association of the expression of its receptor with prognosis. to the paper |
| wb | Cell Signaling Technology anti-Akt polyclonal antibodies were used in western blot in order to study the role for proepithelin in stimulating the migration, proliferation, and anchorage-independent growth of prostate cancer cells. to the paper |
| wb | Cell Signaling anti-pAKT and anti-total AKT were used to perform western blot in order to find out the consequences of expression of activated PIK3CA in ovarian surface epithelium. to the paper |
| ih | Cell Signaling Technology p-Akt antibody was used in immunohistochemistry in order to study the preeminence of Ptch1 as a tumor suppressor in cerebellar granule cells and the role of other genomic events central to the genesis of medulloblastoma. to the paper |
| ip | Cell Signaling Technology rabbit polyclonal anti-Akt and phospho-Akt antibodies were used in immunoprecipitation in order to demonstrate that embryonic lethality can be caused by mitochondrial degeneration rather than apoptosis in ceramide transfer protein mutant mice. to the paper |
| ip, wb | Cell Signaling rabbit polyclonal anti-Akt antibody and anti-Akt-pSer473 antibody were respectively used in immunoprecipitation,western blot and western blot to evaluate the potential relevance of ApoER2 for APC cell signaling mechanisms. to the paper |
| wb | Cell Signaling monoclonal anti-Akt(pan), anti-phospho-Akt (Ser-473) and anti-phospho-Akt (Thr-308) antibodies were used in western blot to study the role for PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. to the paper |
| ip, wb | Cell Signaling mouse anti phospho-Akt Ser473 antibody was used in immunoblots to detect cell lysate in order to conform that autophagy can sensitize apoptosis during deprivation of growth factors. to the paper |
| wb | Cell Signaling anti-PKB antibody and anti-phospho-PKB (Ser473) antibody were used in western blot to investigate whether the PI3K/PTEN pathway may be important in regulating Fas-induced apoptosis in type I and type II cells. to the paper |
| wb | Cell Signaling anti-Akt antibody was used in western blot to study the role for PERK in ER stress. to the paper |
| wb | Cell Signaling anti-p-Ser473 Akt antibody was used in western blot to study the role for Hsp72 in suppression of the oncogene-induced senescence. to the paper |
| wb | Cell Signaling Technology anti-total Akt and anti-phospho-Akt (S473) antibodies were used in western blot to investigate potential links between decreased BRCA1 levels and responses to Tam in ER-positive human breast cancer cell lines (T47D and ZR-75-1). to the paper |
| wb | Cell Signaling anti-Akt antibody was used in western blot in order to research dual functions of Dab1 during brain development. to the paper |
| wb | Cell Signaling antibody against total Akt was used in western blot to detect Akt in mouse embryo fibroblasts (MEFs). to the paper |
| wb | Cell Signaling Technology anti-AKT antibody(1:1000) was used in western blot in order to study the the efficacy of lapatinib for preventing the outgrowth of breast cancer cells in the brain in a mouse xenograft model of brain metastasis. to the paper |
| wb | Cell Signal anti-phospho-Akt antibody was used in western blot to study the role for human AQP5 in the progression of chronic myelogenous leukemia. to the paper |
| wb | Cell Signaling Technology PKB Ser473 antibody was used in western blot in order to demonstrate that increased AA and insulin availability causes changes in anabolic signaling and amounts of enzymes of the ubiquitin-proteasome pathway. to the paper |
| wb | Cell Signaling polyclonal anti-Akt and anti-pAkt antibodies were used in western blot to study the role of IGF-1R in photoreceptor function. to the paper |
| wb | Cell Signaling anti-AKT antibody was used in western blot in order to study the role of acetylation and extra-cellular location of heat shock protein 90α in tumor cell invasion. to the paper |
| wb | Cell Signal phospho-AKT antibody was used in western blot in order to study the role of MMP-2 inhibition in tumor cells by targeting angiogenic components of tumor growth. to the paper |
| wb | Cell Signaling rabbit anti-AKT antibody was used in western blot in order to examine the subcellular signaling pathways activated by heat stress. to the paper |
| ip, wb | Cell Signaling Technology AKT antibody was used in western blot and immunoprecipitation in order to study the role of Jab1 in mediating EGFR signaling. to the paper |
| ih | Cell Signaling Technology rabbit monoclonal anti-pAkt(Thr308) antibody(244F9, #4056) was used in immunohistochemistry to investigate the expressions of EGFR and pEGFR and their correlation with overall and disease-free survival, clinicopathological parameters and biological markers of invasion and angiogenesis. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt (Ser473) antibody and anti-Akt antibody were used in western blot to test the hypothesis that HGF suppresses renal inflammation by inhibiting proinflammatory cytokine expression. to the paper |
| wb | Cell Signaling anti-phospho-Akt (Ser473) and anti-Akt antibodies were used in western blot to study the role for Chagas disease parasite-derived neurotrophic factor in cholinergic gene expression in neuronal PC12 cells. to the paper |
| wb | Cell Signaling Technologies anti-phospho S-473 PKB,anti-phospho T308 PKB and anti-PKB antibodies were used in western blot to identify the pathway and mechanism by which AAs signal to hVps34 to stimulate mTOR complex1 signaling. to the paper |
| ih | Cell Signaling Technology anti-total Akt and anti-pAkt (Ser473) antibodies were used in immunohistochemistry to study the effect of low-dose spironolactone on reactive oxygen species generation and insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat. to the paper |
| wb | Cell Signaling Technology anti-phospho-AKT (Ser473) antibody was used in western blot to study the effect of human herpesvirus 8 chemokines on endothelial survival and virus replication. to the paper |
| wb | Cell Signaling anti-Akt-Ser473 and anti-Akt (total) antibodies were used in western blot to study the role for endocytosis in the regulation of signaling by the Kaposi's sarcoma-associated herpesvirus K1 protein. to the paper |
| wb | Cell Signaling Technology phospho-Akt(Ser473) antibody was used in western blot in order to study the regulation and the role of NAG-1 expression in VES-treated PC-3 human prostate carcinoma cells. to the paper |
| wb | Cell Signaling Technology phospho-anti-AKT antibody(1:1,000) was used in western blot in order to study the mechanisms by which GH and/or IGF-1 regulate sodium and water balance remain. to the paper |
| ip, wb | Cell Signaling Technology anti-total Akt and anti-phosphorylated Akt (Ser473) antibodies were used in immunoprecipitation and western blot to study which of them, oxidative stress and mitochondrial protein phosphorylation , may be responsible for IP-mediated inhibition of MPTP at the start of reperfusion. to the paper |
| wb | Cell Signaling Technology phosphorylated S473 AKT antibody(1:500 dilution) was used in western blot in order to study molecular mechanisms underlying TSH-secreting pituitary tumors (TSHomas). to the paper |
| ih | Cell Signaling Technology anti-phospho-Akt antibody was used in immunohistochemistry in order to study the role of decreased endothelial GSH in the age-related loss of vascular endothelial function. to the paper |
| wb | Cell Signaling antibody to total Akt was used in western blot in order to study the role of Gsk-3β in control of β-cell mass in insulin-resistant diabetic models. to the paper |
| wb | Cell Signaling anti-Akt(1:1000) antibody was used in western blot in order to study the role of trefoil factor 3 (TFF3) in β-cell replication. to the paper |
| ih, wb | Cell Signaling Technology anti-AKT antibody and anti-phospho-AKT antibody were respectively used in western blot and western blot,immunohistochemistry to study the role for expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in mediating uterine leiomyoma growth in sections from human tissue. to the paper |
| wb | Cell Signaling Akt antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-κB activation in a mouse model of skin inflammation. to the paper |
| wb | Cell Signaling Akt antibdoy was used in western blot in order to demonstrate that PM cholesterol influences PIP2-regulated cytoskeletal structure essential for insulin-regulated GLUT4 translocation and glucose transport. to the paper |
| wb | Cell Signaling Technology AKT antibody was used in western blot in order to demonstrate that lithium suppresses Smad3/4-dependent TGF-β-responsive gene transactivation. to the paper |
| wb | Cell Signaling Technology Akt antibody was used in western blot in order to study the role of the VLDLR in inhibiting cell division. to the paper |
| wb | Cell Signaling Technology antihuman rabbit Akt(Ser 473) antibody was used in western blot in order to investigate the effects of CB2 receptor agonists on TNF-α-induced proliferation, migration and signal transduction. to the paper |
| wb | Cell Signalling phosphorilated AKT antibody was used in western blot in order to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt Ser473 antibody(clone 587F11) was used in western blot to study the roles for IL-22 and IL-17 in providing protection to hepatocytes during acute liver inflammation in mices. to the paper |
| wb | Cell Signaling rabbit polyclonal anti-Akt(1:1000) antibody was used in western blot to study the role of birc1 in suppressing apoptosis in the uterus. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt (Ser-473) and anti-Akt antibody was used in western blot to study the role of acetylation, one of the main post-translational regulatory mechanisms, in regulating Fli1 activity in human dermal fibroblast. to the paper |
| ih | Cell Signaling anti-Akt1 antibody was used in immunohistochemistry to determine the incidence of patients with thyroid cancer and associated HT. to the paper |
| wb | Cell Signaling Technology Akt (1:1000) antibody was used in western blot to assesse the effects of cryptotanshinone on macrophage chemotaxis. to the paper |
| wb | Cell Signaling Technology anti-phosphorylated Akt antibody was used in western blot to demonstrate that Ulk1/2 proteins regulate filopodia extension and neurite branching during sensory axon outgrowth. to the paper |
| ic, wb | Cell Signaling Technology anti-pPKB (S-473) antibody was used in western blot and immunocytochemistry to study the role of PDE3B and its interaction with PKB for regulation of specific cAMP pools and signalling pathways by insulin. to the paper |
| wb | Cell Signaling Technologies Akt antibody was used in western blot to demonstrate enhanced DcR3 expression upon EBV reactivation in P3HR1 cells and in EBV-infected 293 cells. to the paper |
| wb | Cell Signaling Technology Akt antibody was used in western blot to study the role of PDCD4 in retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells. to the paper |
| wb | Cell Signaling Technology mouse monoclonal phospho-AKT antibody was used in western blot to examine whether the malignant potential of endometrial cancer enhanced by P-LAP/IRAP is due to increased glucose uptake via the P-LAP/IRAP-mediated activation of insulin signaling. to the paper |
| wb | Cell Signaling Technology phospho-Akt antibody was used in western blot to study the expression and role of Nrdp1 in cancer. to the paper |
| ip, wb | Cell Signaling Technology polyclonal phospho-PKB (Ser-473), monoclonal phospho-PKB (Thr-308) antibodies and mouse monoclonal anti-PKB antibody were respectively used in western blot and western blot, immunoprecipitation to study the role for PKB and megalin in the survival or death of renal proximal tubule cells. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt/protein kinase B (PKB) antibody was used in western blot to study the role for the effect of H-REV107-1 on mitogenic signaling in growth in human non-small cell lung carcinomas. to the paper |
| wb | Cell Signaling Technology rabbit polyclonal anti-Akt and anti-phospho-Akt (Ser473) antibodies were used in western blot to investigate the activation of Akt by FGF19 promoter in human CE cells. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt (Ser-473) and anti-Akt antibodies were used in human HT29 tumors and in western blot to study the role for the effect of receptor tyrosine kinase on lymphatic endothelial cells in the therapy of colon cancer lymph node metastasis. to the paper |
| wb | Cell Signaling anti-phospho-(Ser) Akt substrate antibody was used in western blot to study the interaction of ADAM22 with all 14-3-3 protein family members expressed in the brain in HEK 293T cells. to the paper |
| wb | Cell Signaling Technology anti-phosphorylated AKT (Ser473) antibody was used in human HEK293T cells and in western blot to study the antagonizing of the receptor-type protein tyrosine phosphatase J for effects of RET-derived oncoproteins. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody(phosphorylated) was used in western blot to study the mechanism of protein synthesis inhibition by hypoxia in human breast cancer cells. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to verify that CA-Akt can selectively induce GLT-1 expression. to the paper |
| wb | Cell Signaling Technology anti-total and phospho-Akt antibody was used in western blot to study the inhibition of PI3K reduces MMP expression in Comma-1D mouse mammary epithelial cells retrovirally transduced with PDK1. to the paper |
| wb | Cell Signaling Inc. rabbit polyclonal anti-Akt and anti-phospho-Akt (Ser 473) antibodies were used in primary mouse keratinocytes and in western blot to study the effect of insulin-like growth factor 1 receptor signaling on skin development and skin keratinocyte differentiation. to the paper |
| wb | Cell Signaling Technology polyclonal rabbit antisera to Akt was used in western blot to analyze biology and drug responsiveness of human breast cancer. to the paper |
| wb | Cell Signaling Technology anti-Akt and anti-phospho-Akt (Ser473) antibodies were used in human 1HAEo cell line and in western blot to study the link between the PI3K-Akt pathway and the cigarette smoke (CS) -stimulated epidermal growth factor receptor-mediated FRA-1 induction in non-oncogenic HBE cells. to the paper |
| wb | Cell Signaling anti-total and phospho-Akt antibody was used in western blot to detect total and phospho-Akt in mouse rhabdomyosarcoma cell and Swiss3T3 fibroblasts stably overexpressing Six1. to the paper |
| wb | Cell Signaling Technology anti-Akt and anti-phospho-Akt (Ser473) antibodies were used in human HEK293 cells and in western blot to study the identification and characterization of a novel regulatory subunit of PI3K. to the paper |
| ih, wb | Cell Signaling rabbit anti-phospho-Akt (Ser473) and anti-Akt antibodies were used in tissues sections from mouse and used in western blot, immunohistochemistry to study the functional significance of AP-2alpha in postnatal skin development. to the paper |
| wb | Cell Signaling Technology phospho-Akt (T308) antibody was used in western blot to AKT phosphrylation in chick embryonic fibroblast prepared from White Leghorn embryos. to the paper |
| wb | Cell Signaling AKT antibody was used in western blot to characterize the antiangiogenic and antitumor activity of the hydroxamic derivative LBH589. to the paper |
| wb | Cell Signaling Technology anti-Akt and anti-phospho-Akt (Ser473) antibodies were used in western blot to detect Akt and phosphorylated Akt levels in human renal carcinoma ACHN cells. to the paper |
| wb | Cell Signaling anti-Akt and anti-phospho-Ser473 Akt were used in western blot to detect Akt expression and Akt phosphorylation status, respectively, in human A549 lung adenocarcinoma cells. to the paper |
| wb | Cell Signaling anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in cell extracts of L6 myotubes stimulated with rat recombinant IL-6. to the paper |
| wb | Cell Signaling monoclonal anti-phospho (Ser-473) Akt antibody and anti-Akt antibody were used in primary human aortic endothelial cells (HAECs) and in western blot to study the effect of up-regulation of PTEN on p38 MAPK stress signal-induced inhibition of insulin signaling. to the paper |
| wb | New England Biolabs anti-phospho-AKT antibody was used in mouse B104-1-1 cells and in western blot to study the role for the effect of HER-2/neu on RECK expression in promoting cell invasion. to the paper |
| wb | Cell Signaling polyclonal anti-phospho-Akt (Thr-380) was used in western blot to detect the phosphorylation of AKT in PMEFs derived from 14-day-old embryos of PtenloxP/loxP-mice. to the paper |
| wb | Cell Signaling Technology rabbit anti-Akt antibody was used in western blot to investigate the regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation (EMT). to the paper |
| wb | Cell Signaling Technology rabbit anti-Akt, anti-Ser473-phosphospecific Akt antibodies were used in hamster HIT-T15 cells and in western blot to study the role for the forkhead transcription factor Foxo1 in the interaction between the JNK pathway and PDX-1. to the paper |
| ip, wb | Cell Signaling Technology rabbit anti-total Akt was used in immunoprecipitation to isolate Akt from mouse Ba/F3 cell lysate and in western blot to detect the amount of Akt in mouse Ba/F3 cells, the rabbit anti-phospho-Akt (Ser-473) was used in western blot to detect the amount of phospho-Akt in mouse Ba/F3 cells and human Hep3B cells. to the paper |
| wb | Cell Signaling anti-p-Akt (Ser473) antibody was used in western blot to study the role of CCN in ovarian carcinomas. to the paper |
| ip, wb | Cell Signaling polyclonal AKT and phospho-AKT (Ser473) antibodies were used in western blot and immunoprecipitation to study the effect of SLAM-associated protein in Trk signaling. to the paper |
| ic, wb | Cell Signaling Technology rabbit anti-Akt and anti-phospho-Thr308-Akt antibodies and anti-phospho-Ser473-Akt antibody were respectively used in western blot and western blot,immunocytochemistry to study the effect of the interaction between histone deacetylase inhibitors and protein phosphatase 1 complexes on Akt in human U87MG cells and PC-3 cells. to the paper |
| wb | Cell Signaling Technology anti-phospho--S473-PKB antibody was used in western blot to study amino acids mediate mTOR activation by signaling through class 3 PI3K, hVps34. to the paper |
| wb | Cell Signaling Technology anti-phos-akt antibody was used in western blot to domenstrate that proline 326 in the c terminus of murine cx3cr1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of akt and extracellular signal-regulated kinase in Chinese hamster ovary cells. to the paper |
| wb | Cell Signaling Technology rabbit polyclonal phosphorylated Akt(Ser473) antibody(1:1000) was used in western blot to study whether SCH66336 inhibits angiogenesis of aerodigestive tract cancer cells. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody (which recognizes phosphorylated proteins of Akt) was used in western blot to study the function of protein phosphatase subunit G5PR in B cell receptor induced apoptosis. to the paper |
| wb | Cell Signaling Technology anti-phosphorylated AKT at Ser 473 antibody was used in western blot to study the mechanisms by which RANKL and BSP two factors might induce osteoclastogenesis and bone resorption synergistically under pathological conditions in mouse cells. to the paper |
| wb | Cell Signaling phospho-AKT antibody was used in western blot to investigate regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation. to the paper |
| wb | Cell Signaling phospho-Akt (Thr308) and total Akt antibodies were used in western blot to investigate the repression of RNA polymerase I transcription by PTEN. to the paper |
| wb | Cell Signaling Akt and phospho-Akt (Thr308 and Ser 473) antibodies were used in western blot to investigate the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway by semaphorin 4D/plexin-B1. to the paper |
| ih, wb | Cell Signaling phospho-Akt (Ser-473) and total Akt antibodies, and an IHC-specific anti-phospho-Akt (Ser-473) antibody (1:150) (number 9277S) were used in western blot and immunohistochemistry to investigate the activation of phosphatidylinositol 3-kinase/Akt and transformation by NBS1. to the paper |
| wb | Cell Signaling anti-Akt and anti-phospho-Akt-S473 antibodies were used in western blot to investigate the interaction among Akt, mTOR, and AMPK. to the paper |
| wb | Cell signaling anti-phosphorylated Akt (Thr-308) antibody was used in western blot to study the role of akt in the subcellular localization of JFC1. to the paper |
| wb | New England Biolabs rabbit anti-human Akt was used in western blot to study the changes of retinal gene expression in proliferative vitreoretinopathy. to the paper |
| wb | Cell Signaling anti-phospho Akt phosphorylated serine 473 antibody and anti-pan Akt antibody were used in western blot to study the induction of neuroblastoma cell apoptosis by TrkA. to the paper |
| wb | Cell Signaling Technology rabbit anti-AKT, anti-phospho-Akt (Ser-473), and anti-phospho-Akt (Thr-308) antibodies were used in western blot to study regulation of the integrin-linked kinase (ILK) level, cell shape, and survival signaling through the LIM1-mediated interaction with ILK. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt antibody and anti-Akt antibody were used in western blot to study the relationship between FPR expression and the biologic behavior of glioma cells. to the paper |
| wb | Cell Signaling rabbit polyclonal AKt and Ser473-phosphorylated Akt antibodies were used in western blot to investigate the down-regulation of phospholipase D2 in the EWS-Fli1-knocked down TC-135 cells. to the paper |
| wb | Cell Signaling polyclonal Akt antibody and anti-phosphorylated Akt antibody were used to investigate the role of integrin-linked kinase in Akt phosphorylation and fibroblast survival. to the paper |
| wb | Cell Signaling anti-Akt and anti-phospho-Akt antibodies were used in western blot to identify S6 Kinase 1 as a mTOR-phosphorylating Kinase. to the paper |
| wb | Cell Signaling Technology rabbit anti-Akt and anti-phospho-Akt (Ser) antibodies were used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection. to the paper |
| ih | Cell Signaling Technology rabbit anti mouse P-Akt (Ser 473) polyclonal antibody was used in immunohistochemistry to study epidermal growth factor receptor gene and protein and gefitinib sensitivity in non small-cell lung cancer. to the paper |
| wb | Cell Signaling Technology anti-phospho Akt antibody(9271) and anti-Akt antibody(9272) were used in western blot to study the contribution of Insr signaling in extrahepatic tissues to the control of hepatic glucose fluxes in Insr knockout mice. to the paper |
| wb | Cell Signaling Technology phospho-Akt (Ser-473) antibody was used in western blot to demonstrate that Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. to the paper |
| wb | Cell signaling Technology anti-phospho-Akt (Ser473, 9271) and anti-Akt (9272) antibodies were used in western blot to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3, beta-1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. to the paper |
| wb | Cell Signaling Technology rabbit anti-human phospho-AKT antibody was used in western blot to study CXC chemokine receptor 4 expression in non-small cell lung cancer cells. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt and anti-Akt antibodies were used in New Zealand white rabbits renal proximal tubular cell (RPTCs, which were infected with recombinant adenovirus expressing kinase inactive form of human p38) and in western blot to study the role for the effect of p38 kinase on transactivation of the epidermal growth factor receptor in dedifferentiation of renal epithelial cells after oxidant injury. to the paper |
| wb | Cell Signaling Technology Akt antibody and phospho-Akt antibody was used in Western blot to study the biological function of NAG-1 expression in LNCaP cells. to the paper |
| wb | Cell Signaling anti-p-Akt-Ser473 (no.9271S) antibody was used in Western blot to study the biological function of TRAIL induced apoptosis in human colon cells. to the paper |
| wb | New England BioLabs polyclonal phospho-specific (Ser-473) PKB antibody was used in western blot to study galectin-8 signalling pathway. to the paper |
| wb | Cell Signaling Technology antibody against p-Akt was used in western blot to study the inhibition effect of sphingosine-1-phosphate on nuclear factor kappa B activation and germ cell apoptosis in the human testis independently of its receptors. to the paper |
| wb | Cell Signaling rabbit anti-human phospho Akt (Ser-473) (9271) and Akt (9272) were used in western blot to study the role for phosphoinositide 3-kinase in accelerating postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to study the inducing of platelet-derived growth factor C to liver fibrosis, steatosis, and hepatocellular carcinoma. to the paper |
| wb | New England Biolabs phospho-specific Akt antibody (Ser-473) antibody was used in western blot to study the interaction of Grb10 with 14-3-3. to the paper |
| wb | Cell Signaling rabbit anti-human Akt and phospho-Akt antibodies were used in western blot to the angiogenic phenotype regulation by mitochondrial H2O2 via PTEN oxidation. to the paper |
| wb | Cell Signaling Technology anti-Akt and antiphosphorylated Akt antibodies were used in Western blot to study the biological function of Rac-MKK3/6-p38 pathway. to the paper |
| wb | Cell Signaling Technology antibody against phospho-Akt was used in western blot to detect the activation of Akt in rat PC12 cells. to the paper |
| wb | Cell Signaling Technologies anti-phospho-Akt antibody (Ser-473) and anti-Akt antibodies were used in western blot to study the effect of flow shear stress on Gab1, protein kinase B, and endothelial nitric-oxide synthase in endothelial cells. to the paper |
| ih, wb | Cell Signaling anti-pAkt/Akt antibody was used in western blot and immunohistochemistry to study the activation of the PI3K/Akt signal transduction pathway and increased levels of insulin receptor in protein repair-deficient mice. to the paper |
| wb | Cell Signaling Technology AKT Ser473 antibody was used in western blot to study VEGF mRNA stability in DU145 prostate carcinoma. to the paper |
| wb | Cell Signaling anti-Akt antibody was used in western blot to study the negative regulation of the mammalian target of rapamycin pathway by the stress-inducted proteins RTP801 and RTP801L. to the paper |
| wb | Cell Signaling Technology Phospho-Akt Pathway Sampler Kit (total and phospho-Akt included) was used to study Ciglitazone induced cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to study that kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via akt-glycogen synthase kinase-3 and akt-bad 14-3-3 signaling pathways. to the paper |
| ip, wb | Cell Signaling Technologies rabbit polyclonal Akt antibody was used in immunoprecipitation to isolate Akt from human Ishikawa cells, in western blot to determine the total amount of Akt in Ishikawa cells, Cell Signaling Technologies rabbit polyclonal phospho-Akt antibody was used in western blot to detect the phosphorylation of Akt in Ishikawa cells. to the paper |
| wb | Cell Signaling rabbit anti-phosphorylated-Akt (Ser-473) antibody was used in western blot to study Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. to the paper |
| wb | Cell Signaling Technology polyclonal anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in the nuclear protein extracts isolated from the murine cardiomyocytes treated with various concentrations of IL-18. to the paper |
| wb | Cell Signaling anti-AKT and anti-phospho-AKT (Ser473) antibodies were used in human NK92 cells and in western blot to study the role for the interleukins 2 and 15 in regulating Ets1 expression in human natural killer cells. to the paper |
| wb | Cell Signaling Technology anti-phosphorylated PKB/Akt (serine 473 and threonine 308) and anti-total PKB/Akt antibodies were used in Western blot to study the biological function of protein kinase B/Akt phosphorylation. to the paper |
| wb | Cell Signaling Technology Akt antibody was used in western blot to study the role of KSR1 in regulating intestinal cell fate during cytokine-mediated inflammation. to the paper |
| wb | Cell Signaling Technology antibodies reactive with phospho-Ser-473 AKT, phospho-Thr-308 AKT, and total AKT were used in western blot to study gene regulation by anti-HER2 antibody. to the paper |
| wb | New England Biolabs polyclonal anti-phospho-AKT antibody was used in western blot to study the physiological role of ER palmitoylation in the receptor localization to the cell membrane and in the regulation of the E2-induced cell proliferation. to the paper |
| wb | Cell Signaling Technology pAkt antibody was used in western blot to evaluate the therapeutic potential of the combination of IGFBP-3 and SCH66336. to the paper |
| wb | New England Biolabs antibodies against protein kinase B and phospho-Ser473 protein kinase B were used in western blot to study the interaction of CD98hc (SLC3A2) with beta1 integrins required for transformation. to the paper |
| wb | Cell Signaling Technology anti-total Akt antibody and anti-phospho-Akt (Ser473) polyclonal antibody were used in western blot to study the mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. to the paper |
| ic, ih, wb | Cell Signaling anti-Akt antibody (9272), anti-phospho-Ser-473 Akt antibody (9271), anti-phospho-Ser-308 Akt antibody (9275) and monoclonal anti-phospho-Akt (Ser-473) antibody (587F11) were used in cells and tissue from human cells, and which were respectively used in western blot and immunocytochemistry, immunohistochemistry to study the effect of peptide spanning the A strand of the proto-oncogene TCL1 on Akt kinase activity. to the paper |
| ic | Cell Signaling Technology rabbit polyclonal anti-phospho-Akt antibody was used in immunocytochemistry to detect phospho-Akt in human corneal epithelial (HCE) stimulated with HGF for different times. to the paper |
| ih | Cell Signaling Technology rabbit anti-phospho-protein kinase B (Akt) antibody was used in paraffin sections from mouse and in immunohistochemistry to study the in vivo activities of stromelysin-2 in epithelial repair. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to study that Akt/protein kinase B and endothelial nitric Oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer. to the paper |
| ip, wb | Cell Signaling Technology phospho-Akt (S473) and Akt antibodies were used in western blot and immunoprecipitation to study interleukin 7 effects on T cell acute lymphoblastic leukemia cells. to the paper |
| wb | New England Biolabs monoclonal anti-phospho Akt antibody was used in human cells and in western blot to study the role for Sp1 in Akt-mediated induction of VEGF expression. to the paper |
| wb | Cell Signaling Technology anti-pAkt(Ser 473) antibody and anti-Akt antibody was used in western blot to study the role for Lnk in Tpo mpl signaling and Tpo-mediated megakaryocytopoiesis in mice. to the paper |
| wb | Cell Signaling anti phosphorylated serine 473 of Akt kinase antibody and anti-Akt kinase antibody were used in western blot to study the role for small GTP binding proteins in the growth-promoting and antiapoptotic actions of gastrin in rat exocrine pancreatic cell line AR4 2J. to the paper |
| wb | Cell Signaling anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in human coronary artery endothelial cells (HCAEC) treated with or without VEGF. to the paper |
| wb | Cell Signaling Technology phospho-Akt antibody was used in western blot to demonstrate that IGF-1 and its receptor in regulate post-translational changes in RUNX2 to activate DNA binding in proliferating EC. to the paper |
| wb | Cell Signaling Technology monoclonal anti-phosphorylated Akt (Ser473) antibody(clone 587F11) was used in western blot to study GCP in vitro and in vivo for potential utility as a prostate cancer chemopreventative agent in human prostate cancer cell line. to the paper |
| wb | Cell Signalling Technology anti-phospho-PKB antibody was used in western blot to detect phospho-PKB in HeLa cells with FTI treatment. to the paper |
| wb | Cell Signaling anti-S(P)475 AKT antibody was used in western blot to study the role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. to the paper |
| ih | New England Biolabs rabbit polyclonal anti-phospho-Akt (T308) antibody was used in immunohistochemistry to study HER2/neu overexpression in breast cancer patients. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody and anti-phosphorylated Akt (p-Akt-ser473) antibodies were used in western blot to study the levels of phosphorylated Akt (p-Akt-ser473) and total Akt in response to upstream signals in the beta 1 integrin/PI3K/Akt signal pathway. to the paper |
| ip, wb | Cell Signaling Akt antibody was used in western blot and immunoprecipitation to study the molecular mechanisms downstream of BTC involved in mediating vascular remodeling. to the paper |
| wb | Cell Signaling pAkt antibody was used in western blot to study the coordination between apoptotic and Ub-P'some systems. to the paper |
| wb | Cell Signaling anti-Akt and anti-phospho-Akt antibodies were used in western blot to study interaction between thioredoxin and Txnip as an important mechanism for vascular oxidative stress in diabetes mellitus. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in dissociated sympathetic neurons from postnatal day 1 Sprague-Dawley rats. to the paper |
| ih, wb | Cell Signaling Technology polyclonal anti-phosphorylated Akt (p-Akt; Thr308) antibody was used in human Jurkat cells, paraffin sections from human tumors and were respectively used in western blot and immunohistochemistry to study the role of activated Akt expression in prognosis of pancreatic ductal adenocarcinoma. to the paper |
| wb | Cell Signaling anti-phospho-AKT antibody was used in western blot to detect phospho-AKT in Panc-1 cells. to the paper |
| wb | Cell Signaling Technologies anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in bone marrow neutrophils isolated from male BALB/c mice. to the paper |
| wb | Cell Signaling Technology anti-phospho (Ser473) -Akt antibody was used in western blot to study akt-dependent cell survival by the regulating of ezrin/radixin/moesin Proteins. to the paper |
| wb | Cell Signaling Technology anti-total and phosphorylated Akt antibody was used in western blot to study tumor invasion activity in PANC-1, P/ARK, DLD-1, D/ARK, and SW480 cells. to the paper |
| wb | Cell Signaling anti-Akt antibody was used in mouse osteoblast 2T3 cells and in western blot to study the direct effects of changes in free ionized extracellular calcium concentrations ([Ca2+]o) on osteoblast function and the involvement of the calcium-sensing receptor (CaR) in mediating these responses. to the paper |
| wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in ET-1-treated lung fibroblasts from open lung biopsy specimens from SSc patients. to the paper |
| wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in extract prepared from the striatum of DAT-KO mice with LiCl, vehicle or alphaMPT injection. to the paper |
| wb | New England Biolabs Anti-phospho-Akt Thr308 and anti-phospho-Akt Ser473 antibodies were used in western blot to identify PP2C as a new positive regulator of insulin sensitivity that acts through a direct activation of PI3K in 3T3-L1 adipocytes. to the paper |
| ip, wb | Cell Signaling rabbit anti-phospho-Akt1 antibody was used in western blot and immunoprecipitation to detect phospho-Akt1 in human ejaculate spermatozoa. to the paper |
| wb | Cell Signaling anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in rat pancreatic RIN beta-cell. to the paper |
| wb | Cell Signaling Technology anti-total Akt and phospho-AKT antibody was used in western blot to detect total Akt and phospho-AKT in LKB1-deficient murine embryonic fibroblasts (MEFs). to the paper |
| wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in mouse C2C12 myoblasts transiently transfected with a cDNA construct encoding FLAG-tagged Ndrg2 or infected with adenovirus for the expression of FLAG-tagged Ndrg2. to the paper |
| wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in U251 human glioma cells treated in normoxic or hypoxic conditions in the presence or absence of TPT, LY294002, and rapamycin. to the paper |
| wb | Cell Signaling Technology monoclonal anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in splenic B lymphocytes from p85-deficient mice and the corresponding wild-type mice. to the paper |
| wb | Cell Signaling Technology rabbit polyclonal antibody against Akt and phosphorylated Akt were used in western blot to study neuroprotective role of PRAS and NGF in apoptotic neuronal cell death after stroke. to the paper |
| wb | Cell Signaling Technology rabbit polyclonal anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in NR6 WT cells and NR6 c'973 cells. to the paper |
| wb | Cell Signaling phospho-Akt(Ser473) antibody was used in western blot to study the role of PTEN in PDGF-induced DNA synthesis. to the paper |
| wb | Cell Signaling anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in rat cardiac myocytes infected with recombinant adenoviruses containing human wild type or mutant cDNA of RasGAP, Akt or ILK. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to study the functional expression of the interleukin-11 receptor alpha-Chain and evidence of antiapoptotic effects in human colonic epithelial cells. to the paper |
| wb | Cell Signaling Technology anti-pAkt antibody was used in western blot to detect pAkt in U373 cells with human MEKK3 stable transfection. to the paper |
| wb | Cell Signaling Tech anti-AKT antibody was used in western blot to study the role of Hu1D10 in human chronic lymphocytic leukemia cells. to the paper |
| ip, wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot and immunoprecipitation to detect Akt and phospho-Akt in platelets from Galpha q-deficient or P2Y1-deficient mice. to the paper |
| wb | New England BioLabs polyclonal rabbit anti-AKT kinase and phospho-AKT kinase antibody was used in western blot to detect AKT kinase and phospho-AKT kinase in neutrophils isolated from citrated blood of healthy single donors. to the paper |
| wb | New England Biolabs anti-pAKT antibody was used in western blot to study the production of interleukin 15 by human colon cancer cells associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. to the paper |
| wb | Cell Signalling Tech anti-Akt antibody was used in western blot to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells. to the paper |
| wb | Cell Signaling Technology anti-total AKT1 antibody was used in western blot to detect total Akt1 in P388D1 cells stably transfected with a vector expressing Myc-His-tagged mouse AKT1 (activated) under the control of the cytomegalovirus promoter. to the paper |
| wb | Cell Signaling Technology Akt antibody was used in western blot to study the role of tyrosine phosphorylation in Reelin-stimulated activation of Akt and Src family kinases. to the paper |
| wb | Cell Signaling Technology anti-Phospho-Akt (Ser-473) and anti-Akt antibodies were used in western blot to study the role of adiponectin in angiogenesis. to the paper |
| wb | Cell Signaling Technology anti-Akt and phopho-Akt antibody was used in western blot to detect Akt and phopho-Akt in SK-LMS-1 cells and MDA-MB-231 cells with human TSP1 transfection. to the paper |
| wb | Cell Signaling Technology rabbit anti-AKT and phospho-Akt antibody was used in western blot to detect AKT and phospho-Akt in Hela cells transfected with pUSEamp (+) /myr-Akt1 or pFLAG-PINCH-2. to the paper |
| ip, wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot and immunoprecipitation to detect Akt and phospho-Akt in embryonic rat heart H9c2 cells with GRX transfection. to the paper |
| wb | Cell Signaling Technology anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in CHO cell expressing the IR and IRS-1 transfected with MOR. to the paper |
| wb | Cell Signaling Technology anti-Akt and anti phospho-Akt (Ser-473) antibodies were used in western blot to study the inhibitory effect of the angiotensin II type 2 receptor on VEGF-induced migration and in vitro tube formation of human endothelial cells. to the paper |
| ih | Cell Signaling anti-phospho-Akt for Ser-473 antibody was used in immunohistochemistry to study the role of AGF in epidermal keratinocytes. to the paper |
| ip, wb | New England Biolabs antiphospho Akt and anti-Akt antibodies were used in immunoprecipitation and western blot to study the different antiapoptotic pathways between wild-type and mutated FLT3. to the paper |
| wb | New England BioLabs polyclonal anti-phosphorylated (Ser473) Akt and anti-Akt antibodies were used in rat L6 myoblasts and in western blot to study the role for S100B in inhibiting myogenic differentiation and myotube formation. to the paper |
| wb | Cell Signaling Technology anti-AKT and anti-phospho-AKT antibodies were used in western blot to study the role for Gab1 in oxidative stress in mouse MEF cells. to the paper |
| wb | New England Biolabs anti-phospho-thr308PKB and anti-PKB antibodies were used in mouse cells and in western blot to study the distinct signalling mechanisms that regulate lipopolysaccharide (LPS) -mediated induction of IL-12 p40 and p35 in macrophages. to the paper |
| wb | Cell Signaling anti-Akt and anti-phospho-Akt antibodies were used in western blot to study the effect of adrenomedullin on myocardial infarction and apoptosis after ischemia and reperfusion. to the paper |
| wb | New England Biolabs anti-phosph-Akt and anti-Akt antibodies were used in western blot to study the expression, function, and signaling pathways of PCDGF in human MM. to the paper |
| wb | Cell Signaling Technologies polyclonal anti-phospho-Akt (Thr-308) antibody and polyclonal anti-phospho-Akt (Ser-473) antibody were used in western blot to study Akt1 activation. to the paper |
| wb | Cell Signaling Technology anti-pan-Akt antibody was used in western blot to detect pan-Akt in the embryonic fibroblasts from E14.5 mouse embryos. to the paper |
| wb | Cell Signaling Technology anti-total and phospho-AKT antibody was used in western blot to detect total and phospho-AKT in HeLa Tet-on cells, HeLa Tet-on-inducible FOXO4 stable cells (15-14), and BJAB cells or RCC4 cell stably transfected with a wild-type human VHL expression plasmid. to the paper |
| wb | Cell Signaling Technology phospho-specific Akt and Akt antibody was used in western blot to study Zinc-induced PTEN protein degradation. to the paper |
| ip, wb | Cell Signaling anti-Akt antibody was used in immunoprecipitation to isolate Akt from human neutrophils and in western blot to detect Akt expression in the neutrophils isolated from venous blood obtained from healthy volunteers, Cell Signaling anti-phospho-Ser-473-Akt was used in western blot to detect the phosphorylation of Akt in neutrophils. to the paper |
| ih, wb | Cell Signaling rabbit polyclonal phospho-Akt (serine-473) and Akt antibodies were used in western blot and immunohistochemistry to study copper-zinc superoxide dismutase during transient mouse focal cerebral ischemia. to the paper |
| wb | Cell Signaling Technology rabbit anti-human Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in LNCaP and PC-3 cells. to the paper |
| wb | Cell Signaling Technology anti-phospho-Ser473 Akt antibody was used in rat-1 cells, HEK 293 cells and in western blot to study the effects of activated G q on p110 phosphatidylinositol 3-kinase and Akt. to the paper |
| wb | Cell Signaling anti-phospho-Akt antibody was used in western blot to study that transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. to the paper |
| wb | Cell Signaling Technology anti-AKt and phospho-Akt (Ser473) antibody was used in western blot to study that resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. to the paper |
| ip, wb | New England Biolabs anti-Akt antibody(no. 9272) and anti-Akt-Ser473P antibody(no. 9271) were used in western blot and agarose-conjugated anti-Akt antibody was used in immunoprecipitation to study the role for the effects of LO on NF-kappaB activity in inhibiting Ras-mediated transformation in mouse NIH 3T3 cells. to the paper |
| wb | Cell Signaling anti-phospho-Akt and anti-Akt antibodies were used in western blot to study the effect of resistin on insulin-stimulated glucose uptake and the upstream insulin-signaling components in L6 rat skeletal muscle cells. to the paper |
| wb | Cell Signaling Technology phospho-Akt (Ser-473) antibody was used in western blot to study interleukin-6-dependent insulin resistance in hepatocytes by suppressor of cytokine signaling-3 (SOCS-3). to the paper |
| wb | New England Biolabs anti-Akt antibody was used in western blot to study that extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus. to the paper |
| wb | New England Biolabs rabbit polyclonal antibody which recognizes phospho-Akt-1 (Ser473) was used in western blot to study the role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite. to the paper |
| wb | Cell Signaling against phospho-Akt antibody was used in western blot to study the expression of Akt in the Eker renal tumors. to the paper |
| wb | New England BioLabs anti-Phospho-Akt antibody (Ser-473) was used in western blot to study induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt antibody was used in western blot to study the role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. to the paper |
| wb | Cell Signaling Tech anti-ERK and anti-phospho-ERK antibody were used in western blot to study the role of c-maf in promoting the production of Th2 cytokines mediated by CD25. to the paper |
| wb | Cell Signaling phospho-PKB/Akt (serine 473) antibody was used in western blot to investigate Akt phosphorylation in human microvascular endothelial cells isolated by enzymatic digestion of blood vessels taken from the mesentery of the small bowel (designated MM1 cells). to the paper |
| wb | Cell Signaling Technology phosphorylated Akt/protein kinase B (PKB) (Ser473) antibody was used in western blot to determine if IGFBP-3 might enhance IGF action by influencing intracellular signaling events downstream of the IGF receptor. to the paper |
| wb | New England Biolabs anti-phospho PKB (serine 473) antibody was used in western blot to examine PKB phosphorylation in H69 human SCLC cells. to the paper |
| wb | Cell Signaling Technology Akt and phospho-Akt (Thr-308) antibodies were used in western blot to study 3-phosphoinositide-dependent protein kinase-1 activity regulation. to the paper |
| wb | Cell Signaling anti-phosphoserine Akt antibody was used in western blot to study the phosphorylation of Akt. to the paper |
| wb | New England Biolabs anti-phospho-Akt antibody was used in western blot to study the biological characteristics of insulin/insulin-like growth factor I hybrid receptors. to the paper |
| wb | Cell Signaling Akt and phospho-Akt (Thr308 or Ser473) antibodies were used in western blot to study the Akt activity and Akt phosphorylation. to the paper |
| wb | cell signalling anti-phospho-PKB/Akt1 antibody was used in western blot to study the phosphorylation state of EGFR, ERK, and PKB/Akt1. to the paper |
| wb | New England Biolabs anti-Akt and anti-phospho-Akt antibody were used in western blot to study the role of fibroblast growth factor 1 in signaling via the glycogen synthase kinase-3beta pathway. to the paper |
| wb | New England Biolabs anti-Akt and anti-phosphoAkt polyclonal antibodies were used in western blot to further elucidate the activation mechanism for intracellular signaling mediated by interaction between Dok1 and phosphorylated RET. to the paper |
| wb | New England Biolabs anti-PKB antibody was used in western blot to study the phosphorylation of PTEN. to the paper |
| wb | Cell Signaling polyclonal anti-phospho-AKT (Thr308) antibody was used in primary human keratinocytes and in western blot to study the role for IGF-1 in this delay of the onset of apoptosis through activation of the AKT signaling pathway. to the paper |
| wb | Cell Signaling Technology anti-Akt antibody was used in western blot to study the phosphorylation of Akt. to the paper |
| wb | Cell Signaling Technology AKT antibody was used in western blot to determine the actions of FSH and IGF-I on PI3K/AKT protein kinase signaling in immature rat Sertoli cells. to the paper |
| wb | Cell Signaling Technologies phospho-PKB Ser473 antibody was used in western blot to study the effect of VIIa/tissue factor interaction. to the paper |
| wb | Cell Signaling Technology anti-phosphorylated and unphosphorylated Akt antibodies were used in human SH-EP cells and in western blot to study the effect of insulin-like growth factor I on mannitol-induced degradation of focal adhesion kinase and Akt. to the paper |
| wb | Cell Signaling Technology rabbit anti-PKB, anti-phospho-Ser 473 PKB antibody was used in western blotting to study the survival of IL-2-dependent T cells IL-2 promoted via the PI3K/PKB pathway. to the paper |
| ip, wb | Cell Signaling Technology rabbit antibody referred as the PAS antibody (phospho Akt substrate), which is directed against the Akt phosphomotif RXRXXpS/T, where X is any amino acid, was used in immunoprecipitation to isolate proteins reacting with the PAS antibody from mouse 3T3-L1 adipocytes, and in western blot to detect Akt phosphomotif in 3T3-L1 adipocytes. to the paper |
| wb | Cell Signaling Technology anti-phospho-Akt (Ser473 or Thr308) antibody was used in western blot to study cell survival by GLP-2R signaling. to the paper |
| wb | New England BioLabs Akt antibody was used in western blot to study the characterization of beta-catenin signaling in CaP. to the paper |
| wb | Cell Signaling Technology polyclonal anti-phospho-Akt and anti-Akt antibodies were used in mouse R+ cells (which were ransfected with plasmids encoding HA-RACK1) and in western blot to study the role for the interaction between RACK1 and insulin-like growth factor 1 (IGF-1) receptor in regulating IGF-1-mediated Akt activation and protection from cell death. to the paper |
| ih | Cell Signaling Technology rabbit polyclonal anti-phospho-Akt (Ser 473) antibody was used in immunohistochemistry to study the expression of phospho-specific Akt in human prostate cancer. to the paper |
| ih | Cell Signaling Technology phospho-Akt antibody was used in immunohistochemistry to study endometrial tumorigenesis in Pten heterozygous mice. to the paper |
| wb | Cell Signaling polyclonal phosphoAkt/PKB (Ser-473) antibody was used in western blot to study the role of phosphoinositide 3-kinase beta lipid products in LPA-induced Ras activation. to the paper |
| wb | New England BioLabs anti-phospho-Akt antibody was used in western blot to detect phospho-Akt in D5 and vector HEK293 cells untreated or treated with insulin. to the paper |
| wb | New England BioLabs polyclonal anti-Akt and phospho-Akt antibody was used in western blot to detect Akt and phospho-Akt in A549 cells. to the paper |
| wb | New England BioLabs anti-phospho-AKT polyclonal antibody was used in western blot to investigate a novel mechanism for the regulation of Rac activity and lamellipodia formation by RET tyrosine kinase. to the paper |
| wb | New England Biolabs anti-phospho-Akt(pS473) and anti-Akt antibodies were used in western blot to study the role for ANGPTL3 in endothelial cell adhesion and migration and blood vessel formation in Vivo in human cells. to the paper |
| wb | Cell Signaling Technology PKB/Akt antibody was used in western blot to study the expression of FKHR, FKHRL1, and AFX genes in the rodent ovary. to the paper |
| wb | Cell Signalling Technology antibodies against Akt and p-Akt (Ser473) were used in western blot to study the lethality from liver hemangiomas in a mouse model of TSC1 and the regulation of p70S6 kinase activity in Tsc1 null cells. to the paper |
| wb | Cell Signaling Technology phosphospecific Akt rabbit polyclonal (Ser473) antibody was used in western blot to elucidate the mechanisms by which c-N-Ras promotes cell survival. to the paper |
| wb | New England Biolabs anti-Akt/PKB and anti-phosphorylated Akt/PKB-Ser 473 (pAkt/PKB) antibodies were used in human thyroid carcinoma cells and in western blot to study the role for vitamin D in arresting thyroid carcinoma cell growth and inducing p27 dephosphorylation and accumulation. to the paper |
| wb | New England Biolabs monoclonal anti-phospho-AKT antibody was used in western blot to study the inhibition of UVB-induced apoptosis of human keratinocytes by hepatocyte growth factor/satter factor. to the paper |
| ip | New England Biolabs anti-phospho-Akt (Ser473 and Thr308) antibody was used in Western blot to study the biological roles of Grb10 in the activation of Akt. to the paper |
| wb | New England BioLabs monoclonal Akt and phospho-Akt (Ser 473) 4E2 antibodies were used in western blot to study the mechanism by which WISP-1 promotes tumorigenicity. to the paper |
| wb | Cell Signaling Technology phospho-Akt (Ser 473) and Akt antibodies were used in western blot to study the effects of black tea polyphenols on IGF-I signal transduction pathways in normal prostate epithelial cells and Du145 prostate carcinoma cells. to the paper |
| wb | Cell Signaling antibody recognizing the phosphorylated form of Akt was used in western blot to study the effect of Akt on collagenase gene expression during replicative senescence in human fibroblasts. to the paper |
| wb | New England Biolabs phosphorylated Akt (Ser-473) antibody was used in western blot to study insulin receptor catalytic activity inhibition. to the paper |
| wb | Cell Signaling Technology phospho-AKT (Ser473) and AKT antibodies were used in western blot to study the effect of CCI-779 on the proliferation of a panel of breast cancer cell lines. to the paper |
| wb | New England Biolabs rabbit anti-phospho-Akt antibodies were used in western blot to detect phosphorylated Akt in MDCK cells and human SKBR-3 and BT20 cells. to the paper |
| wb | New England Biolabs phospho-specific polyclonal antibodies to Akt-Thr308 and Akt-Ser473 were used in western blot to study the immportant roles of IR-mediated tyrosine phosphorylation of p62dok for binding GAP and Nck and for inhibiting insulin-stimulated activation of Ras and Akt. to the paper |
| ip | New England Biolabs immobilized Akt antibody was used in immunoprecipitation to isolate Akt from mouse NIH-3T3 cells. to the paper |
| wb | Cell Signaling Technology polyclonal Akt and phospho-Akt (Ser473) antibodies were used in western blot to demonstrate the causal relationship between PTEN loss and overexpression of Bcl-2 in prostate cancer. to the paper |
| wb | New England Biolabs total c-Akt (9272) and phospho-Akt (Ser-473) (9271S) antibodies were used in western blot to study the HGF/SF-c-Met signaling pathways for cell survival and DNA repair regulated by Gab1. to the paper |
| ip, wb | New England Biolabs anti-phospho-Akt (Ser473) antibody that recognizes the phosphorylation site at Ser473 of AKT was used in western blot and immunoprecipition to study the role of Hgs/Hrs and its interacting proteins in signaling for cytokine-mediated c-fos induction. to the paper |
| wb | Cell Signaling antibody against Akt/PKB as well as the phospho-specific antibodies recognizing p-Akt/PKB (Ser473) and p-Akt/PKB (Thr308) were used in western blot to study the regulation of Ca2+/Calmodulin-dependent eNOS activity by the phosphorylation of eNOS Thr495. to the paper |
| wb | New England Biolabs pAkt (Ser473) antibody was used in western blot to study the MV interference with Akt activation during immunosuppression. to the paper |
| ip | Cell Signaling Technology monoclonal phospho-antibody to Akt was used in immunoprecipitation to study the correlation of oxidative preconditioning with apoptosis in L-cells. to the paper |
| wb | New England Biolabs Phospho-specific antibodies for AKT/PKB were used in western blot to demonstrate caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. to the paper |
| wb | New England Biolabs and Cell Signaling Technology rabbit anti-pAkt (Ser-473) antibody was used in western blot to study growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors. to the paper |
| wb | New England Biolabs PhosphoPlus Akt (Ser473) and Akt antibodies were used in western blot to study the effect of XIAP on Akt activity during cisplatin-induced apoptosis in human ovarian epithelial cancer cells. to the paper |
| wb | New England Biolabs Akt phospho-Thr473 and Akt antibodies were used in western blot to study the mechanisms of Raf-1 activation. to the paper |
| wb | New England Biolabs rabbit polyclonal anti-phospho-Akt/protein kinase-B (Ser-473) antibody was used in western blot to investigate erythropoietin effect on neuronal apoptosis after cerebral ischemia and metabolic stress. to the paper |
| wb | New England Biolabs polyclonal anti-Thr308 phospho-specific Akt antibody and polyclonal anti-Ser473 phospho-specific Akt antibody were used in western blot to study the effect of SH2-containing inositol phosphatase 2 in 3T3-L1 adipocytes. to the paper |
| ip, wb | New England Biolabs anti-AKT antibody was used in western blot and immunoprecipitation to study activation of ER by the PI 3-kinase/AKT survival pathways. to the paper |
| wb | New England BioLabs rabbit polyclonal anti-Akt antibody was used in western blot to study activation of endothelial nitric-oxide synthase induced by estrogen in vascular endothelial cells. to the paper |
| ip | New England Biolabs anti-phosho-Ser473-Akt, anti-phospho-Thr308-Akt and anti-Akt antibodies were used in immunoprecipitation to study activation of p38-dependent MK2 in human neutrophils. to the paper |
| wb | New England Biolabs rabbit anti-phospho Akt (Thr308 and Ser473) and rabbit anti-Akt antibodies were used in western blot to study cd19-dependent activation of Akt kinase in B-lymphocytes. to the paper |
R and D SystemsR and D Systems AKT1 products | |
| wb | R&D Systems polyclonal anti-phospho-Akt antibody was used in western blot to study the role of Rit in human neuroblastoma cells for MEK-independent neurite branching. to the paper |
Assay Designs/StressgenAssay Designs/Stressgen AKT1 products | |
| wb | Stressgen anti-Akt and anti-Akt-Ser473 antibody were used in western blot to study arterial eNOS and biosynthesis of tetrahydrobiopterin regulated by increased blood flow. to the paper |
Sigma-AldrichSigma-Aldrich AKT1 products | |
| wb | Sigma polyclonal PKB (Akt) antibody was used in western blot to study galectin-8 signalling pathway. to the paper |
| wb | Sigma anti-Akt(PKB-175) antibody was used in western blot to study GCP in vitro and in vivo for potential utility as a prostate cancer chemopreventative agent in human prostate cancer cell line. to the paper |
Santa Cruz BiotechnologySanta Cruz Biotechnology AKT1 products | |
| wb | Santa Cruz anti-Akt1 antibody was used to perform western blot in order to study the function of SIRT1 in fighting inflammatory and improving insulin sensitivity in adipocytes. to the paper |
| wb | Santa Cruz rabbit polyclonal anti-phospho-AKT antibody was used to detect phospho-AKT in western blot in order to demonstrate that the MAPK/CREB cascade and the STAT-3 signaling pathway mediate H-IL-6-activated neurogenesis and gliogenesis respectively. to the paper |
| ic | Santa Cruz Biotechnology anti-Rac antibody was used in immunocytochemistry in order to demonstrate that the phosphorylation of p130Cas initiates Rac activation and membrane ruffling. to the paper |
| ih | Santa Cruz Biotechnology rabbit polyclonal anti-phospho-Akt (Ser473) antibody was used in immunohistochemistry to study the role for paracrine overexpression of insulin-like growth factor-1 in mammary tumorigenesis in Vivo in formalin-fixed sections from mammary glands of BK5.IGF-1 transgenic mice. to the paper |
| wb | Santa Cruz Biotechnology rabbit polyclonal anti-Akt 1/2 and anti-p-Akt 1/2/3 (Thr 308) antibodies were used in western blot to study the role of the tumor suppressor genes, TSC1 and TSC2, and other members of this pathway in tumorigenesis of OSCC. to the paper |
| wb | Santa Cruz Biotechnology rabbit polyclonal phospho-Akt antibody was used in western blot in order to examine the effects of combining a proteasome inhibitor with an HDAC inhibitor in GBM cell lines. to the paper |
| wb | Santa Cruz Biotechnology anti-AKT antibody was used in western blot to study the effect of human herpesvirus 8 chemokines on endothelial survival and virus replication. to the paper |
| wb | Santa Cruz anti-Akt1/2 antibody(H136) was used in western blot to study the potential binding partners to Cot and their region of association by separating proteins that were pulled-down with various Cot constructs following immunoprecipiation in human HEK293 cells and Hela cells. to the paper |
| wb | Santa Cruz Biotechnology anti-phosphorylated Akt (p-Akt) and anti-nonphosphorylated Akt antibodies were used in western blot to study the role for PI3 kinase/Akt activation in estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of parkinson s disease. to the paper |
| wb | Santa Cruz Biotechnology rabbit anti-Akt (H-136) antibody was used in western blot to study the role of MNAR in 17beta-estradiol (E2)-induced activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. to the paper |
| wb | Santa Cruz Biotechnology polyclonal Akt1 antibody(1:1,000)was used in western blot to study the effect of antagonists of growth hormone-releasing hormone (GHRH) MZ-J-7-138 and JV-1-92 on H460 human non-small cell lung carcinoma (NSCLC) xenografted orthotopically into nude mice. to the paper |
| wb | Santa Cruz Biotechnology anti-AKT and phospho-AKT antibodies (catalogue nos. SC-8312 and SC-7985-R) were used in human cells and in western blot to study the role for anaplastic lymphoma kinase activity in proliferation and survival of anaplastic large-cell lymphoma cells. to the paper |
| wb | Santa Cruz Biotechnology polyclonal rabbit anti-phospho-AKT-Ser-473 antibody antibody was used in western blot to study the effect of down-regulation of BRCA2 expression by collagen type I. to the paper |
| wb | Santa Cruz Biotechnology goat anti-Akt C-20 antibody was used in western blot to study the interaction of Grb10 with 14-3-3. to the paper |
| wb | Santa Cruz Biotechnology monoclonal anti-AKT was used in western blot to study the physiological role of ER palmitoylation in the receptor localization to the cell membrane and in the regulation of the E2-induced cell proliferation. to the paper |
| wb | Santa Cruz Biotechnology Akt1 antibody was used in western blot to evaluate the therapeutic potential of the combination of IGFBP-3 and SCH66336. to the paper |
| wb | Santa Cruz Biotechnology mouse monoclonal anti-Akt antibody was used in western blot to detect Akt in human corneal epithelial (HCE) stimulated with HGF for different times. to the paper |
| ih, wb | Santa Cruz Biotechnology AKT1 antibody was used in western blot to study the role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. to the paper |
| wb | Santa Cruz Biotechnology anti-Akt-1 monoclonal antibody was used in western blot to study akt-dependent cell survival by the regulating of ezrin/radixin/moesin Proteins. to the paper |
| wb | Santa Cruz Biotechnology anti-Akt antibody was used in western blot to identify PP2C as a new positive regulator of insulin sensitivity that acts through a direct activation of PI3K in 3T3-L1 adipocytes. to the paper |
| wb | Santa Cruz Biotechnology anti-AKT antibody was used in western blot to study the production of interleukin 15 by human colon cancer cells associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. to the paper |
| wb | Santa Cruz Biotech anti-Akt antibody was used in western blot to study the inhibition of lysophosphatidic acid acyltransferase beta on proliferative and survival signals in normal cells and apoptosis of tumor cells. to the paper |
| wb | Santa Cruz Biotechnology goat polyclonal anti-Akt antibody (Akt) was used in western blot to demonstrate that p85 alpha and p85 beta modulate PI 3-kinase-dependent signaling by multiple mechanisms and transmit signals independent of PI 3-kinase activation. to the paper |
| wb | Santa Cruz Biotechnology mouse monoclonal anti-Akt and anti-phospho-threonine-308-Akt antibodies were used in thyroid TAD-2 cells and the hepatoma cell line Hep3B and in western blot to study the interaction of calcium/calmodulin-dependent protein kinase II with Raf-1 and the effect of it on integrin-stimulated ERK activation. to the paper |
| ip, wb | Santa Cruz Biotechnology rabbit polyclonal anti-Akt antibody was used in western blot and immunoprecipitation to study the phosphorylation of PED/PEA-15 by Akt in 293 cells were stimulated with insulin. to the paper |
| wb | Santa Cruz Biotechnology rabbit polyclonal anti-Akt (H-136) antibody was used in human HEK 293 cells and rat-1 cells cotransfected with Akt-Myc and in western blot to study the effects of activated G q on p110 phosphatidylinositol 3-kinase and Akt. to the paper |
| wb | Santa Cruz Biotechnology Akt antibody was used in western blot to study the role of Lipocalin-type prostaglandin D2 synthase (L-PGDS)in maintaining the proper equilibrium between proliferation and apoptosis. to the paper |
| wb | Santa Cruz anti-phosphoAkt antibody was used in western blot to study the pathway for platelet-derived growth factor to induce the beta-gamma-secretase-mediated cleavage of alzheimer's amyloid precursor protein. to the paper |
| wb | Santa Cruz Biotechnology polyclonal goat anti-Akt antibody was used in western blot to study the endothelial cell survival and in vitro angiogenesis mediating by CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway. to the paper |
| wb | Santa Cruz Biotechnology anti-Akt antibody was used in western blot to study the role of EWS/FLI-1 in the alteration of mesodermal cell differentiation. to the paper |
| wb | Santa Cruz Biotechnology anti-PKB/Akt1 antibody was used in western blot to study the phosphorylation state of EGFR, ERK, and PKB/Akt1. to the paper |
| wb | Santa Cruz Biotechnology PKB antibody was used in western blot to study the effect of VIIa/tissue factor interaction. to the paper |
| wb | Santa Cruz Biotechnology polyclonal goat anti-human AKT and phosphorylated AKT (P-AKT) antibodies were used in human Kaposi's sarcoma cells (KS cells) and in western blot to study the molecular mechanisms through which HIV-1-Tat protein inhibits vincristine-induced apoptosis of KS cells. to the paper |
| ih | Santa Cruz Biotechnology rabbit polyclonal anti-Akt antibody was used in immunohistochemistry to study the expression of phospho-specific Akt in human prostate cancer. to the paper |
| ip, wb | Santa Cruz Biotechnology anti-Akt1 antibody was used in western blot and immunoprecipitation to detect Akt1 in D5 and vector HEK293 cells untreated or treated with insulin. to the paper |
| ip | Santa Cruz Biotechnology polyclonal anti-Akt antibody was used in immunoprecipitation to study the biological roles of Grb10 in the activation of Akt. to the paper |
| wb | Santa Cruz Biotechnology Akt antibody was used in western blot to study insulin receptor catalytic activity inhibition. to the paper |
| flow, wb | Santa Cruz Biotechnology anti-Akt antibody was used in flow cytometry and western blot to study the role of oxidants and Lyn in SHIP regulation. to the paper |
| ic, ip, wb | Santa Cruz Biotechnology goat polyclonal anti-Akt antibody was used in human HaCaT keratinocytes cells and Rb-deficient human cervical carcinoma (C33A) cells, which were respectively used in immunocytochemistry and immunoprecipitation、western blot, to study the effects of inhibition of protein kinase B (PKB) and PKC zeta on keratin k10-induced cell cycle arrest. to the paper |
| wb | Santa Cruz Biotechnology Akt antibody was used in western blot to detect Akt in mouse NIH-3T3 cells. to the paper |
| ip, wb | Santa Cruz Biotechnologies Akt1 antibody (C-20) was used in western blot and immunoprecipitation to study the MV interference with Akt activation during immunosuppression. to the paper |
| ip, wb | Santa Cruz Biotechnology polyclonal anti-Akt antibody was used in western blot and immunoprecipitation to study the effect of SH2-containing inositol phosphatase 2 in 3T3-L1 adipocytes. to the paper |
Articles Reviewed | |
| 1: | Omedul Islam et al. Interleukin-6 and neural stem cells: more than gliogenesis. 2009 This publication discusses LIFR, CREB, MAPK1, GAD1, SCG10, tyrosine hydroxylase, TUBA1B, PRKACA, NES, STAT3, NTRK1, p53, AKT1, TUBB3, IL6ST, MAP2, IL6R, SLC17A7, and glial fibrillary acidic protein. Reagent reviews based on this publication are available for LIFR, CREB, ERK, GAD, phospho-CREB, pERK, STMN2, TH, tubulin, PKA??-cat, nestin, STAT-3, phospho-STAT-3, TRKA, p53, phospho-TRKA, AKT, III-tubulin, phospho-AKT, gp130, MAP2, IL-6R, VGLUT1, and GFAP. |
| 2: | James W Peacock et al. PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15. 2009 This publication discusses AKT1, NGFR, PTEN, CD3E, PARP1, CD28, FAS, vinculin, PEA 15, CASP8, CASP3, and FADD. Reagent reviews based on this publication are available for PKB, NGFR, PTEN, CD3, PARP, CD28, Geneticin, recombinant human IgG1 Fc and Fas-Fc fusion protein, vinculin, human PEA-15 cDNA clone, propidium iodide, LY294002, QuikChange site-directed mutagenesis kit, caspase-8, Superscript first-strand synthesis system, Lipofectamine 2000, CD95, Platinum Sybr green PCR supermix, caspase-3, Fas, FADD, and PEA-15. |
| 3: | Yang Mei et al. FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation. 2009 Reagent reviews based on this publication are available for SuperScript first-strand RT-PCR kit, Luciferase Assay System kit, TRIzol, and Rneasy kit. |
| 4: | Anna Dubrovska et al. The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. 2009 This publication discusses FGF4, FOXO1, GSK3B, CD44, PIK3CG, insulin, FOXO3, and PROM1. Reagent reviews based on this publication are available for basic FGF, Hepes, RNeasy kit, FoxO1, GSK-3beta, low-melting SeaPlaque CTG agarose, CD44v6, PI3K inhibitor LY294002, PI3K inhibitor NVP-BEZ235, insulin, FoxO3a, and CD133. |
| 5: | Anne Catherine Sprynski et al. The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. 2009 This publication discusses EGFR, IL6, hepatocyte growth factor, AKT1, HBEGF, MAPK1, TNFSF13, STAT3, BCMA, IGF1R, and CD45. Reagent reviews based on this publication are available for PD169540 pan-ErbB kinase inhibitor, RPMI1640, fetal bovine serum, human rIL-6, human rHGF, Akt, human rHB-EGF, MAPK, human rAPRIL, Stat3, HGF, ELISA kit for IL-6, BCMA-Fc, NVP-AEW541 IGF-1R inhibitor, CD45, and IGF-1R. |
| 6: | Brian J Altman et al. Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. 2009 This publication discusses FRAP1, BCL2L11, PUMA, BCL2L1, BAX, BECN1, and ACTA1. Reagent reviews based on this publication are available for DNAse, Dulbecco's modified Eagle's medium, ECL-Plus, SuperScript II Reverse Transcriptase system, protease inhibitor cocktail, Supersignal West Pico Chemiluminescent Substrate, IQ Sybr-Green Supermix, mTOR, Bim, Puma, propidium iodide, Bcl-xL, paraformaldehyde, FITC, Beclin-1, Trizol, Actin, and Bax. |
| 7: | Shun Liang et al. Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation. 2009 This publication discusses AKT1 and PIK3CA. Reagent reviews based on this publication are available for Sybr Green PCR Core reagents, DMEM medium, Vectastain ABC kit, AKT, Gill's hematoxylin, enhanced chemiluminescence detection system, Taq polymerase, LipofectamineTM2000, TRIzol reagent, the Superscript first-strand synthesis kit, and p110. |
| 8: | Takeshi Yoshizaki et al. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. 2009 Reagent reviews based on this publication are available for TRIzol and QIAquick PCR purification kit. |
| 9: | R B Hamanaka et al. PERK-dependent regulation of IAP translation during ER stress. 2009 This publication discusses AKT1. Reagent reviews based on this publication are available for RNase inhibitor, ProLong Gold antifade reagent with DAPI, fetal bovine serum, Penicillin/Streptomycin, nonessential amino acids, L-glutamine, LipofectAMINE Plus, Akt Inhibitor VIII, TRIzol, Superscript II RT, and methionine/cystine-free DMEM. |
| 10: | Giada Monami et al. Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth. 2009 This publication discusses ACTB, MAPK1, and GRN. Reagent reviews based on this publication are available for beta-actin, ERK1, enzyme-linked immunosorbent assay, and proepithelin. |
| 11: | Vladimir L Gabai et al. Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. 2009 This publication discusses MAP2K1, MAP2K2, RAF1, MAPK8, MAPK1, HSPA1A, p53, CDKN1A, and MAPK14. Reagent reviews based on this publication are available for MEK1, MEK2, PC-3, Raf, MCF-7, JNK, Lipofectamine 2000, ERK, Bio-Rad protein assay, Hsp72, p53, p21, and p38. |
| 12: | Xia V Yang et al. Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells. 2009 This publication discusses DAB1 and GSK3B. Reagent reviews based on this publication are available for Dab1, SuperSignal West Pico Chemiluminescent Substrate, LPS, and GSK3. |
| 13: | Xin Wang et al. Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice. 2009 This publication discusses myeloperoxidase and DDIT3. Reagent reviews based on this publication are available for BrdU, phenylenediamine, protein assay, chemiluminescence detection system, TRIZOL reagent, and GADD 153. |
| 14: | J Wen et al. Decreased BRCA1 confers tamoxifen resistance in breast cancer cells by altering estrogen receptor-coregulator interactions. 2009 This publication discusses MAPK1, AKT1, BRCA1, NCOA3, CREBBP, NCOA1, NCOR2, PHB2, and ERBB2. Reagent reviews based on this publication are available for MAPK, DMEM, Akt, RPMI-1640, penicillin/streptomycin, siRNA for BRCA1, BRCA1, Lipofectamine-2000, SRC3, polybrene, CBP, SRC1, protein G-agarose, SMRT, PCR purification kit, REA, and HER2. |
| 15: | Libing Feng et al. Dual functions of Dab1 during brain development. 2009 |
| 16: | Pierre Olivier Frappart et al. Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency. 2009 |
| 17: | Krisztina Kovács de Ostrovich et al. Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo. 2008 This publication discusses AKT1 and ESR1. Reagent reviews based on this publication are available for M-MLV reverse transcriptase, random primers, BCA assay, Vectashield mounting media, ECL Plus, Akt, VECTASTAIN Elite ABC kit, and ER. |
| 18: | Brunilde Gril et al. Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. 2008 This publication discusses ERBB3, ERBB2, CDKN1A, EGFR, MAPK1, MAPK14, and PLCG1. Reagent reviews based on this publication are available for HER3, HER2, phospho HER3, phospho HER2, p21, EGFR, phospho EGFR, p42/44, phospho p42/44 MAPK, p38 MAPK, PLCγ1, and phospho PLCγ1. |
| 19: | Christina Magkou et al. Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas. 2008 This publication discusses progesterone receptor, ERBB2, AKT1, PLAUR, MMP14, FLT1, and EGFR. Reagent reviews based on this publication are available for EDTA, Elite ABC, progesterone receptor, c-erbB-2, Akt, uPAR, MMP-14, Flt-1, and EGFR. |
| 20: | P L Greenhaff et al. Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle. 2008 This publication discusses RPS6KB1, insulin, EIF4EBP1, EEF2, GSK3B, PSMA1, and FRAP1. Reagent reviews based on this publication are available for p70S6k, Insulin, 4E-BP1, TRIzol, eEF2, GSK-3β, RNAse inhibitor, C2 proteasome, PCR universal mix, Western Lightning Chemiluminescence Reagent Plus, nitrocellulose membrane, and mTOR. |
| 21: | Jiaxu Wang et al. Jab1 is a target of EGFR signaling in ERalpha-negative breast cancer. 2008 This publication discusses COPS5, CDKN1B, LMNA, EGFR, and MAPK1. Reagent reviews based on this publication are available for Jab1, p27, Lamin A/C, EGFR, ERK, ERK inhibitor PD98059, protease inhibitor, 0.2 μm nitrocellulose, and Jab1-specific short interfering RNA. |
| 22: | Young Bong Choi et al. Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines. 2008 This publication discusses CANX, VEGFA, MAPK1, FOXO3, BCL2L11, HDAC1, MCL1, CCR8, and AKT1. Reagent reviews based on this publication are available for calnexin, Recombinant human VEGF165, ERK1/2, FOXO3a, Trizol, Bim, SuperScript II RT, HDAC1, RT2Real-Time SYBR green/ROX master mix, Mcl-1, CCR8, and AKT. |
| 23: | A R Smith et al. Lipoic acid significantly restores, in rats, the age-related decline in vasomotion. 2008 This publication discusses NOS3. Reagent reviews based on this publication are available for eNOS and phospho-eNOS. |
| 24: | Myrto Giannopoulou et al. Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-kappaB signaling. 2008 This publication discusses IL6, NFKB1, NFKBIB, AKT1, NFKBIA, RELA, GSK3B, RANTES, and hepatocyte growth factor. Reagent reviews based on this publication are available for human IL-1β, dithiothreitol, bromophenol blue, peptide NF-κB SN50, protease inhibitor, IκBβ, phosphatase inhibitor, IL-6, methanol, Akt, DMEM, NaCl, IκBα, Tween 20, p65 NF-κB, newborn calf serum, SuperSignal West Pico chemiluminescent substrate kit, GSK-3β, Tris-HCl, enzyme-linked immunosorbent assay kit for RANTES protein, human HGF, SDS, ChIP assay kit, glycerol, and RANTES. |
| 25: | Konstantinos J Mavrakis et al. Tumorigenic activity and therapeutic inhibition of Rheb GTPase. 2008 This publication discusses p53. Reagent reviews based on this publication are available for SuperScript III Reverse Transcriptase, doxorubicin, propidium iodide, TaqMan Universal PCR Master Mix, p53, TRIzol, and SuperScriptIII kit. |
| 26: | Anush Oganesian et al. Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells. 2008 This publication discusses VEGFA and MAPK3. Reagent reviews based on this publication are available for recombinant VEGF, protease inhibitor cocktail, BCA assay, and Erk1. |
| 27: | Linda Yu et al. Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas. 2008 This publication discusses IGF1R, insulin receptor, IRS1, MAPK3, SHC1, AKT1, PIK3CA, and GRB2. Reagent reviews based on this publication are available for non-essential amino acids, hydrogen peroxide, Fetal Bovine Serum, IGF-IR, IRβ, IR, IRS-I, MAPKp44/42, Shc, AKT, PI3K, Liquid DAB large volume substrate-chromogen system, Grb2, Mayer’s hematoxylin, Protein A- sepharose CL-4B Beads, and IGF-IRβ. |
| 28: | Christine C Tomlinson et al. Critical role for endocytosis in the regulation of signaling by the Kaposi's sarcoma-associated herpesvirus K1 protein. 2008 This publication discusses PIK3CG, SYK, CLTC, transferrin receptor, and EEA1. Reagent reviews based on this publication are available for LY294002, Piceatannol, clathrin-HC, TfR, and EEA1. |
| 29: | Sanjukta Chakraborty et al. Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. 2008 This publication discusses RPS6KB1. Reagent reviews based on this publication are available for Dulbecco's modified Eagle's medium, DNA isolation kit, Revertaid™ H Minus First Strand cDNA Synthesis Kit, p70S6K1, and Western Lightning Chemiluminescence Reagent kit. |
| 30: | Changxue Lu et al. Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors. 2008 This publication discusses FOXO3, BAD, cyclin D1, CDK4, FRAP1, BCL2L11, DCTN2, RPS6KB1, and GSK3B. Reagent reviews based on this publication are available for phosphorylated Fox-O3a, Complete mini-EDTA-free protease inhibitors, BAD, Bradford, phosphorylated BAD, Cyclin D1, CDK4, phosphorylated mTOR, Bim, mTOR, dynamitin, phosphorylated p70S6K, p70S6K, GSK-3β, and Fox-O3a. |
| 31: | Guido Lastra et al. Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat. 2008 |
| 32: | Emily M Horvath et al. Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance. 2008 This publication discusses tyrosinase, PTPN1, CAV1, GLUT4, AKT2, and TBC1D4. Reagent reviews based on this publication are available for phosphotyrosine, DMEM, protein tyrosine phosphatase-1B, Fetal bovine serum, bovine calf serum, caveolin-1, GLUT4, PIP2, phospho-Akt2, and AS160. |
| 33: | Pawan Gulati et al. Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. 2008 This publication discusses PIK3R4, BECN1, PIK3C3, RHEB, FRAP1, RPS6KB1, MAPK3, GSK3B, CALM1, and EIF4EBP1. Reagent reviews based on this publication are available for hVps15, QuikChange II Site-Directed Mutagenesis Kit, Tris, beclin, HEPES, hVps34, Rheb, NaCl, mTOR, EGTA, NaHCO3, S6K-1, wortmannin, KCl, KH2PO4, chemiluminescence kit, CaCl2, Erk, PreScission protease, glucose, GSK3, Protein A-Sepharose, BSA, FRAP, Protein G-Sepharose, Tween-20, raptor, MgCl2, CaM, and 4E-BP1. |
| 34: | Mira Choi et al. Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 This publication discusses PIK3CG, CSF2RA, CSF2RB, MAPK14, IL8RA, IL8, MAPK8, FN1, FPR1, NFKBIA, MAPK1, ITGB2, and ANXA1. Reagent reviews based on this publication are available for LY294002, GM-CSF-receptor, GM-CSF, SB202190, IL-8-receptor, IL-8, SP600125, Fibronectin, fmlp, PBS, RPMI, IκBα, DMEM, c-Jun kinase, fetal calf serum, p38 mitogen-activated protein kinase, glutamine, extracellular signal-regulated kinase (ERK), penicillin/streptomycin, CD18, and annexin I. |
| 35: | Mariana Varela et al. A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma. 2008 This publication discusses SRC, HSP90AA1, JAK1, PDGFA, KDR, and EGFR. Reagent reviews based on this publication are available for SRC (family) Damnacanthal, HSP 90 inhibitor 17-DMAG, JAK inhibitor I, PDGF Inhibitor I, VEGF receptor 2 kinase inhibitor III, PDGF Inhibitor II, PDGF Inhibitor III, Hsp90, SRC (family) PP1, PDGF inhibitor AG 1296, SRC (family) Genistein, PDGF inhibitor AG 2043, SRC (family) Inhibitor I, EGFR inhibitor PD 153035, SRC (family) Inhibitor II, EGFR inhibitor AG 1478, SRC (family) Emodin, HSP 90 inhibitor Herbimycin A, SRC (family) SU 6656, HSP 90 inhibitor Geldanamycin, SRC (family) Lavendustin C, and HSP 90 inhibitor Radicicol. |
| 36: | M Rajesh et al. CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration. 2008 This publication discusses MAPK1, MAPK8, CNR1, CB2, and MAPK14. Reagent reviews based on this publication are available for phosphor-ERK1/2, SAPK/JNK 1/2, CB1, phospho-SAPK/JNK 1/2, CB2, Trizol LS reagent, RNase-free DNase, chemiluminescence detection kit, RIPA lysis buffer, nitrocellulose membranes, p38 MAPK, phospho-p38 MAPK, and ERK1/2. |
| 37: | Chunrong Yu et al. Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 This publication discusses XIAP, SNRPE, MAPK1, p53, MAPK14, CDKN1B, cytochrome c, GSK3B, MCL1, UBASH3B, CDKN1A, CASP9, CASP8, CDKN1C, CASP3, BCL2L1, RB1, AKT1, PARP1, cyclin D1, RAF1, MAPK8, and BID. Reagent reviews based on this publication are available for XIAP, B-Raf, MEK1/2, p53, p38, p27, cytochrome c, MG132, GSK3β, Mcl-1, p70S60K, p21, caspase 9, caspase 8, p57, caspase 3, Bcl-xL, pRB, Akt, protease inhibitor cocktail, PARP, cyclin D1, protein G-agarose beads, Raf-1, JNK, and Bid. |
| 38: | Min-Huei Liang et al. Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling. 2008 This publication discusses SMAD2, MAPK1, BAX, AKT1, GSK3A, GSK3B, CREB, p300, SERPINE1, CREBBP, PLAT, BCL2L1, and CTNNB1. Reagent reviews based on this publication are available for pSmad2/3, ERK, trypsin, Bax, AKT, DNase I, pGSK3αSer21, ECL Plus Western blotting detection system, fetal bovine serum, pGSK3βSer9, dual luciferase reporter assay, L-glutamine, pGSK-3αβTyr279/216, Mercury Pathway Profiling Luciferase System, pCREBSer133, p300, PAI-1, pERK, CBP, tPA, pAKTSer476, agarose gel, GSK-3α, ethidium bromide, GSK -3β, Bcl-xL, β-catenin, and CREB. |
| 39: | Ashok K Dilly et al. Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors. 2008 Reagent reviews based on this publication are available for aprotinin, PMSF, chloroform, NaCl, methanol, Tris-HCl, Tween-20, BCA reagent, bovine serum albumin, Triton X-100, enhanced chemiluminescence, glycerol, DMEM, EGTA, HEPES, MgCl2, EDTA, Na3VO4, leupeptin, and SDS. |
| 40: | Binhui Wu et al. Proteomics analysis of immunoprecipitated proteins associated with the oncogenic kinase cot. 2008 This publication discusses MAP3K8, PDIA2, NFKB1, MAP2K1, HSP90AA1, HSPA1A, HSPA5, and ABIN 2. Reagent reviews based on this publication are available for Cot, PDI, p105/p50, MEK1/2, Hsp90, Hsp70, Grp78, and Abin2. |
| 41: | Alok Sharma et al. Phosphorylation of p130Cas initiates Rac activation and membrane ruffling. 2008 This publication discusses tyrosinase. Reagent reviews based on this publication are available for Tyr. |
| 42: | Arnulfo Quesada et al. PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. 2008 This publication discusses IGF1. Reagent reviews based on this publication are available for recombinant human IGF-1, 3,3-diaminobenzidine tetrahydrochloride, and Permount mounting medium. |
| 43: | Peter Kamenicky et al. Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly. 2008 This publication discusses STAT5B, IGF1, tyrosinase, TUBA1B, JAK2, IGF1R, and MAPK1. Reagent reviews based on this publication are available for STAT5, IGF-1, tyrosine, Ly294002, α tubulin, AG490, DNA polymerase, TRIZOL reagent, phospho-STAT5, IGF-IRa, phospho-p44/42 MAPK, p44/42 MAPK, and ECL+ detection kit. |
| 44: | Patrick T Fueger et al. Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function. 2008 This publication discusses EGF, EGFR, and TFF3. Reagent reviews based on this publication are available for EGF, AG1478, BrdU labeling reagent, protease inhibitor, phosphatase inhibitor, ECL Advance, and TFF3. |
| 45: | Young Kwang Chae et al. Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML). 2008 This publication discusses BCR, ABL1, ACTB, and AQP5. Reagent reviews based on this publication are available for leupeptin, Bcr, c-Abl, actin, RPMI medium, Opti-MEM I reduced serum medium, fetal bovine serum, TRIzol, probe for AQP5, aprotinin, and AQP5. |
| 46: | Minsub Shim et al. Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism. 2008 This publication discusses MAPK1, MAPK8, MAPK14, PARP1, and HSPB2. Reagent reviews based on this publication are available for gentamycin, DNase I, fetal bovine serum, SuperScript II reverse transcription system, BCA protein assay kit, Power SYBR Green PCR Master Mix, ERK, polybrene, phospho-ERK, enhanced chemiluminescence reagent, puromycin, JNK, SV total RNA isolation kit, phospho-JNK, mRNA isolation kit, phospho-p38, PARP, LipofectAMINE 2000, p38, dual luciferase assay kit, and Hsp27. |
| 47: | Chandramu Chetty et al. Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer. 2008 This publication discusses SP1, PIK3CG, AKT1, TIMP3, VEGFA, PECAM 1, KDR, and MAPK1. Reagent reviews based on this publication are available for RPMI-1640, Sp1, fetal bovine serum, PI3K, penicillin, AKT, streptomycin, phospho-AKT, MEM medium, TIMP-3, VEGF, CD31, VEGFR2, Protein A/G PLUS-Agarose, phospho-VEGFR2, TIMP-3 siRNA, ERK, and phospho-ERK. |
| 48: | Hongguang Wei et al. Heat stress activates AKT via focal adhesion kinase-mediated pathway in neonatal rat ventricular myocytes. 2008 This publication discusses PTK2, PIK3R1, PTK2B, and integrin linked kinase. Reagent reviews based on this publication are available for FAK, FAKpy397, PI3K p85, PYK2, and ILK. |
| 49: | Yonghua Yang et al. Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. 2008 This publication discusses HSP90AA1, CHIP, DNAJB1, CDK5R1, RAF1, and MMP2. Reagent reviews based on this publication are available for Ac-K69-hsp90α, HEK293T, Lipofectamine Plus, MDA-MB-468, MDA-MB-231, CHIP, hsp40, hsp90α, p23, cRaf, and MMP2. |
| 50: | Katsuya Tanabe et al. Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. 2008 This publication discusses GSK3B, insulin, GYS1, glucagon, IRS2, Ki 67, PDX1, and CDKN1B. Reagent reviews based on this publication are available for total Gsk-3α/β, insulin, glycogen synthase phosphorylated on Ser 641 and 645, glucagon, Irs2, Ki67, Pdx1, Pdx-1, ECL Advance Western Blot Detection kit, p27kip1, and Gsk-3β. |
| 51: | Samantha J Clarke et al. Inhibition of mitochondrial permeability transition pore opening by ischemic preconditioning is probably mediated by reduction of oxidative stress rather than mitochondrial protein phosphorylation. 2008 This publication discusses insulin. Reagent reviews based on this publication are available for insulin, Bicinchoninic acid-based (BCA) protein assay, and ECL/ECL+ detection. |
| 52: | Yan Yin et al. Estrogen suppresses uterine epithelial apoptosis by inducing birc1 expression. 2008 This publication discusses CASP9, NAIP, and AKT1. Reagent reviews based on this publication are available for caspase-9, NAIP, and Akt. |
| 53: | Nsikan Akpan et al. Chagas' disease parasite-derived neurotrophic factor activates cholinergic gene expression in neuronal PC12 cells. 2008 This publication discusses MAP2K1, NTRK1, and PIK3CG. Reagent reviews based on this publication are available for QuantiTect SYBR Green PCR kit, DMEM, fetal calf serum, MEK inhibitor U0126, DC protein assay, TrkA-tyrosine kinase inhibitor K252a, Western Lightning Chemiluminescence Reagent Plus, PI3-kinase inhibitor LY294002, Trizol reagent, chloroform, SuperScript III reverse transcription kit, and Platinum Taq DNA polymerase High Fidelity Kit. |
| 54: | Shawn D Larson et al. Increased incidence of well-differentiated thyroid cancer associated with Hashimoto thyroiditis and the role of the PI3k/Akt pathway. 2007 This publication discusses AKT2 and PTEN. Reagent reviews based on this publication are available for Akt2 and PTEN. |
| 55: | Lauren A Zenewicz et al. Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. 2007 |
| 56: | Cheng-Hsun Ho et al. Epstein-Barr virus transcription activator Rta upregulates decoy receptor 3 expression by binding to its promoter. 2007 This publication discusses TNFRSF6B. Reagent reviews based on this publication are available for DcR3. |
| 57: | Faiyaz Ahmad et al. Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. 2007 This publication discusses HSP90AA1, COX4I2, CAV1, HSPA5, GOLGA2, NUP62, ICAT, ADCY5, 14 3 3, and IRS1. Reagent reviews based on this publication are available for HSP-90, COX IV, caveolin-1, BiP, GM130, nucleoporin p62, β-catenin, adenylate cyclase, 14-3-3, and IRS-1. |
| 58: | Yoshihide Asano et al. Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation. 2007 This publication discusses TNK2, SMAD2, MAPK1, KAT2B, SP1, ETS1, CREBBP, and GAP43. Reagent reviews based on this publication are available for AcK, Smad2, ERK, PCAF, Sp1, Ets1, CBP, and calmodulin binding peptide. |
| 59: | Xiang Zhou et al. Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. 2007 This publication discusses NTRK1, ULK1, ULK2, and PICALM. Reagent reviews based on this publication are available for TrkA, Ulk1, Ulk2, and clathrin. |
| 60: | James G Greger et al. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. 2007 This publication discusses SRC, PTPRO, PIK3R1, MAPK1, GSK3A, PARP1, PELP1, and AKT1. Reagent reviews based on this publication are available for cSrc, phosphotyrosine, p85, Erk, GSK3, PARP, PELP/MNAR, and Akt. |
| 61: | Bulent Ozpolat et al. Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells. 2007 This publication discusses EIF4G2, CDKN1B, CDKN1A, WT1, and TGM2. Reagent reviews based on this publication are available for DAP5, p27Kip1, p21Waf1/Cip1, WT1, and Transglutaminase 2. |
| 62: | M-J Don et al. Cryptotanshinone inhibits chemotactic migration in macrophages through negative regulation of the PI3K signaling pathway. 2007 This publication discusses MAPK14, MAPK1, and MAPK8. Reagent reviews based on this publication are available for p38 MAPK, ERK1/2, and JNK. |
| 63: | Kiyosumi Shibata et al. P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling. 2007 This publication discusses insulin receptor, IRS1, GLUT4, oxytocinase, and PIK3R1. Reagent reviews based on this publication are available for insulin receptor, IRS-1, GLUT4, P-LAP/IRAP, and p85 PI-3 kinase. |
| 64: | Robert B Rebhun et al. Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. 2006 This publication discusses LYVE 1, podoplanin, PECAM 1, PROX1, MAPK3, KDR, EGFR, and FLT4. Reagent reviews based on this publication are available for LYVE-1, podoplanin, CD31, Prox-1, ERK1/2, VEGFR-2, EGFR, and VEGFR-3. |
| 65: | Yanlin Yu et al. The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis. 2006 |
| 66: | Chen-Fuh Lam et al. Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin. 2006 |
| 67: | Cora Weigert et al. Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells. 2006 This publication discusses IRS1, PRKCD, STAT3, and IL6R. Reagent reviews based on this publication are available for IRS-1, PKC-delta, STAT-3, and IL-6R. |
| 68: | F E Utama et al. Human prolactin receptors are insensitive to mouse prolactin: implications for xenotransplant modeling of human breast cancer in mice. 2006 This publication discusses STAT5A, STAT5B, MAPK3, and STAT3. Reagent reviews based on this publication are available for Stat5, Stat5b, ERK1, ERK, and Stat3. |
| 69: | Li-Bin Li et al. Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype. 2006 |
| 70: | Philipp Voigt et al. Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B. 2006 |
| 71: | Weihua Wan et al. Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells. 2006 This publication discusses MAPK3, STAT3, and ALK. Reagent reviews based on this publication are available for ERK1/2, STAT3, and ALK. |
| 72: | Christopher N Davis et al. Proline 326 in the C terminus of murine CX3CR1 prevents G-protein and phosphatidylinositol 3-kinase-dependent stimulation of Akt and extracellular signal-regulated kinase in Chinese hamster ovary cells. 2006 This publication discusses MAPK1. Reagent reviews based on this publication are available for ERK. |
| 73: | Zhihui Xie et al. 3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases. 2006 This publication discusses PDPK1. Reagent reviews based on this publication are available for PDK1. |
| 74: | Nathan J Gödde et al. Efficient ADAM22 surface expression is mediated by phosphorylation-dependent interaction with 14-3-3 protein family members. 2006 This publication discusses AKT1 and CANX. Reagent reviews based on this publication are available for Akt and calnexin. |
| 75: | Seiji Ueno et al. Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility. 2006 This publication discusses AKT1, STAT3, MAPK1, MAPK3, IL6, and RHOD. Reagent reviews based on this publication are available for Akt and phospho-Akt, STAT3 and phospho-STAT3, p42 MAPK and phospho-p42 MAPK, p44 MAPK and phospho-p44 MAPK, IL-6, and Rho. |
| 76: | Xuan Wang et al. AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. 2006 |
| 77: | Marianna Sadagurski et al. Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. 2006 |
| 78: | Florian Hohla et al. Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel. 2006 This publication discusses PTGS2, HRAS, and GHRHR. Reagent reviews based on this publication are available for Cox-2, K-Ras, and GHRH-R. |
| 79: | Angela Iervolino et al. The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins. 2006 This publication discusses MAPK1. Reagent reviews based on this publication are available for ERK 1/2 and ERK. |
| 80: | Dan Kawamori et al. The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation. 2006 |
| 81: | David Z Qian et al. Targeting tumor angiogenesis with histone deacetylase inhibitors: the hydroxamic acid derivative LBH589. 2006 This publication discusses MAPK1, HIF1A, CXCR4, HIST2H3A, and TUBGCP5. Reagent reviews based on this publication are available for ERK1/2, HIF-1, CXCR4, histone H3, and tubulin. |
| 82: | Yahya Tamimi et al. FGF19 is a target for FOXC1 regulation in ciliary body-derived cells. 2006 This publication discusses FOXC1, MAPK14, MAPK3, MAPK1, AKT1, BAD, and MAPK8. Reagent reviews based on this publication are available for FOXC1, p38 and phospho-p38, ERK1 and phospho-ERK1, ERK2 and phospho-ERK2, Akt and phospho-Akt, BAD and phospho-BAD, and JNK and phospho-JNK. |
| 83: | Celso Caruso-Neves et al. PKB and megalin determine the survival or death of renal proximal tubule cells. 2006 This publication discusses BAD and ZO 1. Reagent reviews based on this publication are available for Bad and ZO-1. |
| 84: | Ying H Shen et al. Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cel. 2006 This publication discusses NOS3, PDK1, PTEN, MAPK14, MAPK8, MAP3K11, and MAP2K3. Reagent reviews based on this publication are available for eNOS, PDK1, PTEN, p38 MAPK, JNK, MLK3, and MKK3/MKK6. |
| 85: | Xiao-Jun Qi et al. Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. 2006 This publication discusses BCL2L11 and HSP90AA1. Reagent reviews based on this publication are available for Bim and Hsp-90. |
| 86: | Anna Moshnikova et al. The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway. 2006 This publication discusses MAPK1, MAP2K1, and MAP2K2. Reagent reviews based on this publication are available for ERK, phospho-ERK, MEK1 and phospho-MEK1, and MEK2. |
| 87: | Ming-Chuan Hsu et al. HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. 2006 This publication discusses MAPK1. Reagent reviews based on this publication are available for ERK. |
| 88: | Qin Zhang et al. A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression. 2006 This publication discusses PRKCZ, FOSL1, ELK1, PDK1, AKT1, EGFR, MAP2K1, RAF1, PAK1, and CREB. Reagent reviews based on this publication are available for PKC zeta, FRA-1, Elk1, PDK1, Akt, EGFR, MEK1, c-Raf, PAK1, and CREB. |
| 89: | Sohye Kang et al. Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase. 2006 This publication discusses PIK3CB. Reagent reviews based on this publication are available for p110beta. |
| 90: | Irina Nazarenko et al. H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling. 2006 This publication discusses HRAS, CAV1, MAPK3, GSTA1, PTK2, and EGFR. Reagent reviews based on this publication are available for RAS, caveolin-1, p44/42 MAP kinase, GST, FAK, and EGFR. |
| 91: | Lily Yen et al. Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth. 2006 This publication discusses ERBB3, ERBB2, MAPK1, and RNF41. Reagent reviews based on this publication are available for ErbB3, ErbB2, ERK, and FLRF/Nrdp1. |
| 92: | Eileen Connolly et al. Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. 2006 This publication discusses EEF2, EIF4E, RPS6KB1, TSC2, FRAP1, EIF4EBP1, and EIF2S1. Reagent reviews based on this publication are available for eEF2, eIF4E, p70S6k, TSC2, mTOR, 4E-BP1, and eIF2alpha. |
| 93: | Francis Edwin et al. The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. 2006 This publication discusses PTEN. Reagent reviews based on this publication are available for PTEN and phospho-PTEN. |
| 94: | Filippo Acconcia et al. Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol. 2005 This publication discusses MAPK1, CAV1, FLNB, and AKT1. Reagent reviews based on this publication are available for extracellular signal-regulated kinase (ERK), caveolin-1, β-actin, and AKT. |
| 95: | Annett Hahn-Windgassen et al. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity. 2005 This publication discusses ACACA, EIF4EBP1, RPS6KB1, TSC2, PRKAA1, RPS6, and ACTB. Reagent reviews based on this publication are available for phospho-ACC-S79, phospho-4E-BP-S65, S6K1, phospho-TSC2-T1462, AMPK, phospho-S6-S235/236, TSC2, and beta-actin. |
| 96: | Michael N Corradetti et al. The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. 2005 This publication discusses RPS6, EIF4EBP1, GSK3B, and TSC2. Reagent reviews based on this publication are available for S6, 4EBP1, GSK3beta, and TSC2. |
| 97: | Shougang Zhuang et al. p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. 2005 This publication discusses AKT1, SRC, MAPK14, EGFR, and MAPK3. Reagent reviews based on this publication are available for Akt, Src, p38, EGF receptor, and ERK1/2. |
| 98: | MinHee K Ko et al. Regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation. 2005 This publication discusses COL1A1, COL1A2, PDIA2, and SERPINH1. Reagent reviews based on this publication are available for type I collagen alpha1, type I collagen alpha2, PDI, and Hsp47. |
| 99: | Bo Chen et al. A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth. 2005 |
| 100: | Fei Chen et al. Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation. 2005 This publication discusses p300 and PTPRCAP. Reagent reviews based on this publication are available for p300 and p65. |
| 101: | Konstantinos G Drosopoulos et al. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. 2005 This publication discusses MAP2K1, TNFRSF10A, CFLAR, TNFRSF10B, TNFRSF10C, TNFRSF10D, FADD, FAS, AKT1, ITGB1, CASP8, PARP1, and MAPK1. Reagent reviews based on this publication are available for p-MEK1/2, DR4, Flip, DR5, TRAIL-R1, DcR1, TRAIL-R2, DcR2, FADD, Fas, p-Akt-Ser473, CD29, caspase-8, PARP, and p-ERK1/2,ERK-2. |
| 102: | Xuefeng Zhang et al. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005 This publication discusses FLT4, MAPK1, EGFR, VEGFC, and COL4A3. Reagent reviews based on this publication are available for Flt-4(VEGFR-3), ERK, EGFR, VEGF-C, α3, and VEGFR-3. |
| 103: | Paloma Valverde et al. BSP and RANKL induce osteoclastogenesis and bone resorption synergistically. 2005 |
| 104: | Jean-François Lavoie et al. TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism. 2005 This publication discusses CDKN1A, p53, BAX, MAPK1, MAPK8, AKT1, MAPK3, BCL2L1, CASP3, and PARP1. Reagent reviews based on this publication are available for p21WAF, p53, Bax, phospho-ERK, active JNK, phospho Akt, ERK-1, JNK-1, Bcl-XL, cleaved caspase-3, and cleaved-PARP. |
| 105: | Cheng Zhang et al. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. 2005 This publication discusses TBP, RPS6KB1, cyclin D1, CDKN1B, and ACTB. Reagent reviews based on this publication are available for TBP, phospho-S6K1, cyclin D1, p27, and actin. |
| 106: | Yan Xing et al. Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis. 2005 This publication discusses BCL2L11, CD45, CCND2, CD3D, NFKBIA, CD5, RB1, CD21, BCL2L1, CD23, IL2RA, CD69, CD43, MAPK14, AKT1, MAPK3, and MAPK8. Reagent reviews based on this publication are available for Bim, B220, cyclin D2, CD3, IκBα, CD5, Rb, CD21, Bcl-XL, CD23, CD25, CD69, CD43, p38, Akt, Erk1/2, and JNK1/2. |
| 107: | John R Basile et al. Semaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway. 2005 This publication discusses PIK3R1, PTK2B, and SRC. Reagent reviews based on this publication are available for p85, PYK2, phospho-PYK2, Src, and phospho-Src. |
| 108: | Hee Yun et al. Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma. 2005 This publication discusses ARNT, PRKAA2, ACTN1, PRKAA1, MAPK1, MAPK8, MAPK14, AKT1, ACACA, LKB1, and HIF1A. Reagent reviews based on this publication are available for HIF-1 beta, VEGF, alpha-actinin, AMPK alpha Thr172, AMPK alpha, ERK1 and -2 (Thr202/Tyr204), stress-activated protein kinase/JNK (Thr183/Tyr185), p38 (Thr180/Tyr182), AKT Ser473, acetyl-CoA carboxylase (ACC) Ser79, LKB1, and HIF-1 alpha. |
| 109: | Sigal Gery et al. Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells. 2005 This publication discusses CYR61, MAPK1, and HBXIP. Reagent reviews based on this publication are available for CCN1, ERK, and XIP. |
| 110: | Xiao-Feng Le et al. Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. 2005 This publication discusses PCNA, ERBB3, and ERBB2. Reagent reviews based on this publication are available for PCNA, HER3, and HER2. |
| 111: | Chang-Shi Chen et al. Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes. 2005 This publication discusses PIK3CA, H3F3A, PDK1, CTMP, MAPK3, TRB3, MAPK14, MAPK8, PPP1CA, PPP2R4, nucleolin, CDKN1A, and PIK3R1. Reagent reviews based on this publication are available for p110, histone H3, PDK-1, CTMP, ERK1/2, TRB3, p38, PI3K, JNK, PP1, PP2A, nucleolin, p21, and p85. |
| 112: | Laura Suomalainen et al. Sphingosine-1-phosphate inhibits nuclear factor kappaB activation and germ cell apoptosis in the human testis independently of its receptors. 2005 This publication discusses CHUK, S1PR1, S1PR2, and MAPK1. Reagent reviews based on this publication are available for I kappa B alpha, EDG-1, EDG-5, p-ERK, and ERK. |
| 113: | Zhen Xu et al. Molecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survival. 2005 |
| 114: | Kohsuke Kanekura et al. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. 2005 This publication discusses Cu Zn superoxide dismutase, RAC1, CDC42, RHOA, ACTB, APP, PSEN1, PSEN2, and AKT1. Reagent reviews based on this publication are available for SOD1, Rac1, Cdc42, RhoA, actin, APP, PS1, PS2, and phosphorylated-Akt (Ser-473). |
| 115: | Yen-Chung Chen et al. Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. 2005 This publication discusses NBN, GSK3B, and FRAP1. Reagent reviews based on this publication are available for NBS1, phospho-GSK3 beta, and phospho-mTOR. |
| 116: | Ji-Youn Han et al. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer. 2005 This publication discusses HIF1A, MAPK1, GSK3A, VHL, and HSP90AA1. Reagent reviews based on this publication are available for HIF-1, p44/42MAPK, GSK-3, VHL, and HSP90. |
| 117: | Hang Yin et al. Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways. 2005 This publication discusses SRC, AKT1, BAD, GSK3B, BCL2L1, and 14 3 3. Reagent reviews based on this publication are available for c-Src, Akt, Bad, GSK-3 beta, Bcl-xL, and 14-3-3. |
| 118: | Ilchung Shin et al. H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells. 2005 This publication discusses MAPK8, MAPK1, MAPK14, MAP2K3, RAF1, RAC1, PIK3CA, and MAP2K6. Reagent reviews based on this publication are available for JNK, phosphorylated JNK, ERK-1/2, phosphorylated ERK-1/2, p38, phosphorylated p38, MKK3, phosphorylated MKK3/MKK6, phosphorylated Raf-1, Rac1, PI3K, and MKK6. |
| 119: | Takahiro Nobukuni et al. Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. 2005 This publication discusses RHEB, RPS6KB1, TSC2, RPS6, EIF4EBP1, PIK3CA, and PIK3C3. Reagent reviews based on this publication are available for Rheb, phospho-T389-S6K, phospho-S939-TSC2, phospho-S240/244-S6, phospho-T70-4E-BP1, PI3K, and hVs34. |
| 120: | Jian-Bin Wang et al. Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. 2005 This publication discusses SOS1, HRAS, MAPK8, and MAPK1. Reagent reviews based on this publication are available for Sos1, H-Ras, JNK, and MAPK. |
| 121: | Loredana Moro et al. Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. 2005 This publication discusses TUBB1, AKT2, PIK3CA, PIK3R1, UBA52, BRCA2, and ITGB1. Reagent reviews based on this publication are available for beta-tubulin, AKT 1/2, p110, p85alpha, ubiquitin, BRCA2, and beta1 integrin. |
| 122: | Minsub Shim et al. Protein kinase C-dependent regulation of NAG-1/placental bone morphogenic protein/MIC-1 expression in LNCaP prostate carcinoma cells. 2005 This publication discusses GDF15. Reagent reviews based on this publication are available for NAG-1. |
| 123: | Ye Zhou et al. Formylpeptide receptor FPR and the rapid growth of malignant human gliomas. 2005 This publication discusses glial fibrillary acidic protein, FPR1, MAPK1, MAPK14, MAPK8, AKT1, STAT3, Bcl 2, BCL2L1, HIF1A, and VEGFA. Reagent reviews based on this publication are available for GFAP, FPR, ERK1/2, phospho-ERK1/2, p38 MAPK, phospho-p38 MAPK, JNK, phospho-JNK, Akt, phospho-Akt, STAT3, phospho-STAT3, Bcl-2, Bcl-xL, HIF-1alpha, and VEGF. |
| 124: | Federico Cappuzzo et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. 2005 This publication discusses EGFR. Reagent reviews based on this publication are available for EGFR. |
| 125: | Haruka Okamoto et al. Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. 2005 |
| 126: | J Calvin Coffey et al. Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy. 2005 This publication discusses PIK3R1 and PIK3CG. Reagent reviews based on this publication are available for p85alpha and p110gamma. |
| 127: | Bysani Chandrasekar et al. Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes. 2005 |
| 128: | Rinat Arbel-Goren et al. Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8. 2005 This publication discusses LGALS8, CDKN1A, MAPK1, PARP4, and MAPK8. Reagent reviews based on this publication are available for galectin-8, p21/Cip1, MAPK, PARP, and JNK. |
| 129: | Hitoshi Ogawa et al. Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. 2005 This publication discusses MADCAM1 and RELA. Reagent reviews based on this publication are available for MAdCAM-1 and p65 NF-kappaB subunit. |
| 130: | Christine Farrar et al. Activation of the PI3K/Akt signal transduction pathway and increased levels of insulin receptor in protein repair-deficient mice. 2005 |
| 131: | Richard Seonghun Nho et al. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. 2005 This publication discusses ITGB1, CASP9, GSK3B, and integrin linked kinase. Reagent reviews based on this publication are available for beta1 integrin, cleaved caspase-9, GSK3beta, ITGB1, and ILK. |
| 132: | Jennifer L Johnson et al. Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation. 2005 This publication discusses JFC1, STX7, PFKFB4, and RAB27A. Reagent reviews based on this publication are available for JFC1, syntaxin 7, phosphoglycerate kinase 1, and Rab27a. |
| 133: | Kip M Connor et al. Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation. 2005 This publication discusses GSK3B, HIF1A, PTEN, and VEGFA. Reagent reviews based on this publication are available for GSK3-beta, HIF-1alpha, PTEN, and VEGF. |
| 134: | Roderick J Phillips et al. Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia ind. 2005 This publication discusses HIF1A and CXCR4. Reagent reviews based on this publication are available for HIF1-alpha and CXCR4. |
| 135: | Jean S Campbell et al. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. 2005 This publication discusses ACTA2, PDGFRB, MAPK3, MAPK1, AKT1, and PDGFRA. Reagent reviews based on this publication are available for alpha-SMA, PDGF beta, PDGFR beta, ERK-1, ERK-2, Akt, and PDGFR alpha. |
| 136: | Margrit Hollborn et al. Changes in retinal gene expression in proliferative vitreoretinopathy: glial cell expression of HB-EGF. 2005 This publication discusses HBEGF, MAPK3, MAPK1, and AKT1. Reagent reviews based on this publication are available for HB-EGF, p44MAPK, p42MAPK, and Akt. |
| 137: | Guillaume Bossis et al. Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation. 2005 This publication discusses FOS, MAPK3, MAPKAPK2, and AKT1. Reagent reviews based on this publication are available for c-Fos, phospho-T232 c-Fos, p42/44 mitogen-activated protein kinase, phospho-MAPKAPK2, and phospho-AKT. |
| 138: | Susanne Urschel et al. Phosphorylation of grb10 regulates its interaction with 14-3-3. 2005 This publication discusses YWHAB and GRB10. Reagent reviews based on this publication are available for 14-3-3 beta and Grb10. |
| 139: | Ju-Eun Oh et al. Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. 2005 This publication discusses TGFBI, ITGA2, ITGA3, ITGA5, ITGA6, ITGB1, ITGB4, ITGAV, involucrin, TGFB1, and TGM1. Reagent reviews based on this publication are available for beta-ig-h3, integrin alpha-2, integrin alpha-3, integrin alpha-5, integrin alpha-6, integrin beta-1, integrin beta-4, integrin alpha-v, involucrin, TGF-beta-1, and transglutaminase. |
| 140: | Zheng-Gen Jin et al. Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells. 2005 This publication discusses NOS3, PIK3R1, and GAB1. Reagent reviews based on this publication are available for phospho eNOS, eNOS, PI3K p85, and Gab1. |
| 141: | Satoshi Nozawa et al. Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells. 2005 This publication discusses FLI1, MAPK3, RPS6KB1, CCND3, PDGFRB, and PIK3R1. Reagent reviews based on this publication are available for Fli-1, ERK1/2, Thr421/Ser424-phosphorylated p70S6K, cyclin D3, platelet-derived growth factor receptor (PDGFR), and PI3K p85. |
| 142: | Stefan Kippenberger et al. Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor. 2005 This publication discusses AKT1, CASP8, and EGFR. Reagent reviews based on this publication are available for PKB/Akt, caspase 8, and EGFR. |
| 143: | Marina K Holz et al. Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. 2005 This publication discusses RPS6KB1 and FRAP1. Reagent reviews based on this publication are available for S6K1 and mTOR. |
| 144: | Kin Yip Lo et al. SLAM-associated protein as a potential negative regulator in Trk signaling. 2005 This publication discusses NTRK2, SH2B1, NTRK1, and PLCG1. Reagent reviews based on this publication are available for TrkB, SH2B, TrkA, phospho-TrkA (Tyr490), and phospho-TrkA (Tyr674/675), and PLC gamma-1. |
| 145: | Eric M Grund et al. Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. 2005 This publication discusses PIK3R1, ETS2, FLII, MAPK1, CCND3, MAPK10, MAPK14, MKNK1, EIF4E, and ETS1. Reagent reviews based on this publication are available for PI3K p85, Ets2, Fli1–1, ERK2, cyclin D3, MAP kinase, p38, MNK1, eIF4E, and Ets1. |
| 146: | James G Burchfield et al. Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta. 2004 This publication discusses PRKCQ and PRKCE. Reagent reviews based on this publication are available for PKC theta and PKC epsilon. |
| 147: | Shinji Yamamoto et al. Prognostic significance of activated Akt expression in pancreatic ductal adenocarcinoma. 2004 This publication discusses AKT1, AKT2, and MAPK1. Reagent reviews based on this publication are available for Akt, Akt2, and ERK1/2. |
| 148: | Azucena Kakazu et al. HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway. 2004 This publication discusses BAD and VDAC1. Reagent reviews based on this publication are available for Bad and VDAC1. |
| 149: | Francesco Andreozzi et al. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. 2004 |
| 150: | Vinzenz Stepan et al. Role of small GTP binding proteins in the growth-promoting and antiapoptotic actions of gastrin. 2004 |
| 151: | Yingzi Yue et al. Ras GTPase-activating protein binds to Akt and is required for its activation. 2004 This publication discusses integrin linked kinase, RPS6KA1, MAPK3, MAPK1, RPS6, EIF4E, SPTB, and RASA1. Reagent reviews based on this publication are available for ILK, p90RSK, p44 MAPK, p42 MAPK, S6 ribosomal protein, eIF4E, beta-spectrin, and RasGAP. |
| 152: | Reuben J Shaw et al. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. 2004 This publication discusses PRKAA1. Reagent reviews based on this publication are available for AMPK. |
| 153: | Brian A Pierchala et al. Nerve growth factor promotes the survival of sympathetic neurons through the cooperative function of the protein kinase C and phosphatidylinositol 3-kinase pathways. 2004 |
| 154: | Makoto Hiromura et al. Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. 2004 This publication discusses FOXO1, BAD, MAPK3, and MAPK14. Reagent reviews based on this publication are available for FKHR, BAD, p44/42 MAP kinase, and p38 MAP kinase. |
| 155: | Meng Qiao et al. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway. 2004 This publication discusses RUNX2 and MAPK1. Reagent reviews based on this publication are available for AML3 and ERK1/2. |
| 156: | Stephan Kiessling et al. Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells. 2004 This publication discusses NFKBIA, IL11RA, IL6ST, EP4, JAK1, STAT3, ACTB, and AKT1. Reagent reviews based on this publication are available for IkappaBalpha, IL-11Ralpha, gp130, EP-4, Jak1, phosphotyrosine Jak1, STAT3, phosphotyrosine STAT3, beta-actin, and Akt. |
| 157: | Michael J Piatelli et al. Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells. 2004 This publication discusses RB1. Reagent reviews based on this publication are available for pRb. |
| 158: | Akihiro Iwabu et al. Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway. 2004 This publication discusses PRKCA, MARCKS, MAPK3, MAPK1, AKT1, MYL1, and PRKCD. Reagent reviews based on this publication are available for PKC alpha, MARCKS, p44 ERK, p42 ERK, Akt, MLC, and PKC delta. |
| 159: | Julien Mazieres et al. Loss of RhoB expression in human lung cancer progression. 2004 This publication discusses RHOB, p53, Bcl 2, MAPK3, MAPK1, and AKT1. Reagent reviews based on this publication are available for RhoB, p53, BclII, extracellular signal-regulated kinase 1, extracellular signal-regulated kinase 2, and AKT. |
| 160: | Andrew P Mone et al. Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells. 2004 This publication discusses HLA-DRB1, EGFR, ZAP 70, SYK, CASP9, CASP8, COL11A2, and AKT1. Reagent reviews based on this publication are available for HLA-DR, HER2, ZAP-70, Syk, caspase-9, caspase-8, PARP, and AKT. |
| 161: | Weiya Xia et al. Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients. 2004 This publication discusses ERBB2 and CDKN1A. Reagent reviews based on this publication are available for HER2/neu and p21. |
| 162: | Atsushi Suzuki et al. ARK5 is a tumor invasion-associated factor downstream of Akt signaling. 2004 This publication discusses FRAP1, AKT1S1, and FOXO3. Reagent reviews based on this publication are available for mTOR, Akt substrate, and FKHRL1. |
| 163: | Costanza Emanueli et al. Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer. 2004 |
| 164: | Atsushi Saito et al. Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor. 2004 This publication discusses AKT1S1, 14 3 3, and BAD. Reagent reviews based on this publication are available for pPRAS, 14-3-3, and Bad. |
| 165: | Fang Yan et al. Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. 2004 This publication discusses MAPK3, RAF1, BIRC3, endothelin 1, PECAM 1, AKT1, MAPK1, NFKBIA, MAP2K2, and KSR1. Reagent reviews based on this publication are available for ERK1/2, Raf-1, cIAP2, endothelin, CD31, Akt, p38, IκBα, MEK1/2, and KSR1. |
| 166: | Ajoy K Samanta et al. Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB. 2004 This publication discusses MEKK3, PARP1, CASP3, CASP8, XIAP, AKT1, and ACTB. Reagent reviews based on this publication are available for MEKK3, PARP, caspase 3, caspase 8, xIAP, pAkt, and actin. |
| 167: | Mizuo Mifune et al. Signal transduction of betacellulin in growth and migration of vascular smooth muscle cells. 2004 This publication discusses PTPRO, MAPK3, MAPK1, EGFR, and ERBB2. Reagent reviews based on this publication are available for phosphotyrosine, ERK1, ERK2, p38 MAPK, EGFR, and ErbB2. |
| 168: | Joao T Barata et al. Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. 2004 This publication discusses MAPK1, CDKN1B, STAT5A, SLC2A1, ZAP 70, AKT1, GSK3B, FOXO1, and MAP2K1. Reagent reviews based on this publication are available for phospho-Erk1/2 (T202/Y204), p27kip1, STAT5, Glut1, ZAP-70, phospho-STAT5A/B (Y694/Y699), Akt, phospho-GSK-3 beta, phospho-FKHR(FOXO1) (T24)/phospho-FKHRL1(FOXO3a) (T32), and phospho-MEK1/2 (S217/S221). |
| 169: | Seoung Woo Lee et al. Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. 2004 This publication discusses LAMB1 and IRS1. Reagent reviews based on this publication are available for laminin and IRS. |
| 170: | Matthew Wherlock et al. Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase. 2004 This publication discusses RHOB, EGFR, EEA1, CD63, MAPK3, MAPK1, MAPK8, and MAPK14. Reagent reviews based on this publication are available for RhoB, EGF receptor, EEA1, CD63, Erk1, Erk2, JNK, and p38. |
| 171: | Xu Shi-Wen et al. Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. 2004 This publication discusses ACTA2, MAPK1, MAPK3, paxillin, ezrin, and moesin. Reagent reviews based on this publication are available for alpha-SMA, p42 MAPK, p44 MAPK, paxillin, ezrin, and moesin. |
| 172: | Debra L Bemis et al. A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo. 2004 This publication discusses PARP1, p53, CDKN1A, and CDKN1B. Reagent reviews based on this publication are available for poly(ADP-ribose) polymerase, p53, p21, and p27. |
| 173: | Melita M Dvorak et al. Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones. 2004 |
| 174: | Wei Tong et al. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. 2004 |
| 175: | Derek Strassheim et al. Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. 2004 |
| 176: | Saveria Aquila et al. Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway. 2004 This publication discusses AKT2, ESR1, AKT3, ESR2, PIK3R1, MAPK3, MAPK1, PDPK1, GSK3A, and AKT1. Reagent reviews based on this publication are available for Akt2, ERalpha, Akt3, ER-beta, ERbeta, p85, ERK1, ERK2, PDK1, GSK-3, and Akt1. |
| 177: | Karen L Wu et al. The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. 2004 This publication discusses Willin. Reagent reviews based on this publication are available for ERM. |
| 178: | Noriyuki Ouchi et al. Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. 2004 This publication discusses PRKAB1, MAPK1, and NOS3. Reagent reviews based on this publication are available for AMPK, ERK, and eNOS. |
| 179: | Neil C Henderson et al. CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. 2004 This publication discusses SLC3A2 and CD69. Reagent reviews based on this publication are available for CD98, CD98hc, and CD69. |
| 180: | Hong Xia et al. Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway. 2004 This publication discusses PIK3R1 and PTK2. Reagent reviews based on this publication are available for PI3K-p85 subunit and FAK. |
| 181: | Monika Krampert et al. Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. 2004 |
| 182: | P Christian Schulze et al. Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein. 2004 This publication discusses thioredoxin and MAPK14. Reagent reviews based on this publication are available for thioredoxin and p38 MAPK, phospho-p38 MAPK. |
| 183: | Ho-Young Lee et al. Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells. 2004 This publication discusses MAPK3, CASP3, AKT1, BAX, BCL2L1, PARP1, MAPK8, MAPK1, GSK3B, and IGF1R. Reagent reviews based on this publication are available for p44 MAPK, caspase-3, Akt1, Bax, Bcl-xL, PARP, JNK, p38 MAPK, Akt, GSK-3, and IGF-1R. |
| 184: | Annamaria Rapisarda et al. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. 2004 This publication discusses HIF1A, ARNT, RPS6KB1, and EIF4EBP1. Reagent reviews based on this publication are available for HIF-1 alpha, HIF-1 beta, p70S6K, and 4E-BP1. |
| 185: | Soochong Kim et al. Akt activation in platelets depends on Gi signaling pathways. 2004 |
| 186: | Brigitte Kasper et al. Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase. 2004 This publication discusses MAPK14, MAPK3, LYN, HCK, and FGR. Reagent reviews based on this publication are available for p38, Erk, Erk1, Lyn, Hck, and Fgr. |
| 187: | Lenin Mahimainathan et al. Inactivation of platelet-derived growth factor receptor by the tumor suppressor PTEN provides a novel mechanism of action of the phosphatase. 2004 This publication discusses PTEN, PDGFRB, CDKN1B, MAP2K2, EGFR, PTPN1, and MAPK3. Reagent reviews based on this publication are available for PTEN, PDGFR, p27kip1, Erk1/2 MAPK, EGFR, PTP1B, and Erk1/2. |
| 188: | Antonio E Rusiñol et al. AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis. 2004 This publication discusses BAD, HSPA1A, BCL2L11, and BCL2L1. Reagent reviews based on this publication are available for BAD, HSP70, BIM, and BCL-xL. |
| 189: | Takeshi Yoshizaki et al. Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. 2004 |
| 190: | Nabendu Pore et al. Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism. 2004 This publication discusses GTF3A, SP1, and SP3. Reagent reviews based on this publication are available for AP2, Sp1, and Sp3. |
| 191: | Md Ruhul Abid et al. Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB. 2004 This publication discusses NFKBIA, RELA, FOXO1, ACTB, MAPK3, MAPK1, MAPK8, and CREB. Reagent reviews based on this publication are available for IkappaB, p65 NF-kappaB, FKHR, beta-actin, Erk1, Erk2, JNK, and CREB. |
| 192: | Jean-Martin Beaulieu et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. 2004 |
| 193: | Kurt J Sales et al. Prostaglandin E2 mediates phosphorylation and down-regulation of the tuberous sclerosis-2 tumor suppressor (tuberin) in human endometrial adenocarcinoma cells via the Akt signaling pathway. 2004 This publication discusses TSC2. Reagent reviews based on this publication are available for Tuberin and phosphotuberin. |
| 194: | Mario Schiffer et al. A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. 2004 This publication discusses WT1, TGFB1, SMAD2, MAPK1, and MAPK14. Reagent reviews based on this publication are available for WT-1, TGF-1, Smad2, Erk, and p38. |
| 195: | Hiroaki Murata et al. Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. 2003 |
| 196: | Wengang Wang et al. PC cell-derived growth factor (granulin precursor) expression and action in human multiple myeloma. 2003 This publication discusses MAPK1 and STAT3. Reagent reviews based on this publication are available for MAP kinase and STAT3. |
| 197: | Yu-Wen Zhang et al. Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation. 2003 This publication discusses MET, thrombospondin 1, MAPK3, and MAPK1. Reagent reviews based on this publication are available for h-Met, thrombospondin 1, p44 MAPK, and p42 MAPK. |
| 198: | Susan Eliazer et al. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. 2003 This publication discusses MYOD1, MYOG, FLI1, EWS, MAPK1, and MAPK14. Reagent reviews based on this publication are available for MyoD, myogenin, FLI-1, EWS, ERK1/2, and p38 MAPK. |
| 199: | Weidong Wu et al. Zinc-induced PTEN protein degradation through the proteasome pathway in human airway epithelial cells. 2003 This publication discusses PTEN, UBA52, and ACTB. Reagent reviews based on this publication are available for PTEN, ubiquitin, and beta-actin. |
| 200: | DiAnna L Hynds et al. Rit promotes MEK-independent neurite branching in human neuroblastoma cells. 2003 This publication discusses RIT1, MAPK1, and MAPK3. Reagent reviews based on this publication are available for Rit, ERK, and ERK 1/2. |
| 201: | Hiroki Kuniyasu et al. Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. 2003 This publication discusses PDX1, TUBA4A, transforming growth factor alpha, IL15RA, NCAM1, CDKN1A, CCNE1, PCNA, VEGFA, IL2RB, and IL 15. Reagent reviews based on this publication are available for IL-2 receptor subunit gamma, tubulin, TGF-alpha, IL-15R, CD56, p21Waf1, cyclin E, PCNA, VEGF, IL-2 receptor subunit ß, and IL-15. |
| 202: | Alessandra Trencia et al. Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. 2003 |
| 203: | Davide Gianni et al. Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway. 2003 This publication discusses PDGFB, galectin 4, MAPK1, and APP. Reagent reviews based on this publication are available for PDGF, Gal4DBD, phosphoERK, and APP. |
| 204: | Yosuke Minami et al. Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia. 2003 This publication discusses FLT3. Reagent reviews based on this publication are available for FLT3. |
| 205: | Kazuo Kato et al. Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. 2003 This publication discusses AKT1, BAD, MAPK14, CASP3, and adrenomedullin. Reagent reviews based on this publication are available for Akt, Bad, p38 MAPK, cleaved caspase-3, and AM. |
| 206: | Nobuo Noshita et al. Copper-zinc superoxide dismutase affects Akt activation after transient focal cerebral ischemia in mice. 2003 |
| 207: | Yu Li et al. Morphine induces desensitization of insulin receptor signaling. 2003 This publication discusses MAPK3, RPS6KA1, GSK3A, GRB2, insulin receptor, SHC1, and IRS1. Reagent reviews based on this publication are available for ERK, p90rsk, gsk3, Grb2, IR, Shc, and IRS1. |
| 208: | Monique C A Duyndam et al. Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite. 2003 This publication discusses AKT1, MAPK13, MAPK8, MAPK9, MAPK14, HIF1A, RAF1, TOP1, and p53. Reagent reviews based on this publication are available for Akt-1, MAPK, phospho-Akt-1, JNK1, JNK2, p38, HIF-1 alpha, Raf-1, topoisomerase I, and p53. |
| 209: | Dirk Haller et al. Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. 2003 This publication discusses ACTB, RELA, MAPK14, SMAD3, SMAD4, NFKBIA, AKT1, HIST3H3, and SMAD2. Reagent reviews based on this publication are available for beta-actin, NF-kappaB p65, phospho-NF-kappaB p65 (RelA), p38, Smad3, Smad4/DPC4, IkappaBalpha, Akt, histone 3, and Smad2. |
| 210: | Kohjiro Ueki et al. Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling. 2003 This publication discusses RPS6KB1, GSK3A, CEBPE, GSK1, PPARA, MAPK8, SART3, MAPK14, BAD, MAP2K4, 14 3 3, PTPRO, IRS1, IRS2, RPS6KA2, and PIK3R2. Reagent reviews based on this publication are available for p70S6K, GSK3, C/EBP, glycogen synthase, PPAR, JNK, p110, p38 MAPK, Bad, SEK1, 14-3-3, phosphotyrosine, IRS-1, IRS-2, p90RSK, and p85. |
| 211: | Lisa M Ballou et al. Activated G alpha q inhibits p110 alpha phosphatidylinositol 3-kinase and Akt. 2003 This publication discusses GNAQ, PIK3CA, PIK3CB, and PIK3R1. Reagent reviews based on this publication are available for Gαq, p110alpha, p110beta, and p85alpha. |
| 212: | Xiao-Ding Peng et al. Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. 2003 |
| 213: | Maddalena Illario et al. Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation. 2003 This publication discusses RAF1, MAPK1, MAPK3, KRAS, PAK1, MAP2K1, and CAMK2A. Reagent reviews based on this publication are available for Raf-1, p42 MAPK, p44/p42 MAPK, Ras, Pak, Mek-1, and CaMKII. |
| 214: | Tiho Miralem et al. Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus. 2003 This publication discusses BRCA1, MAPK1, ITGB4, ERBB2, CDK4, and ACTB. Reagent reviews based on this publication are available for BRCA1, Erk-2, beta4 integrin, ErbB-2, Cdk4, and actin. |
| 215: | Tomohiko Fukuda et al. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. 2003 This publication discusses paxillin. Reagent reviews based on this publication are available for paxillin. |
| 216: | Guglielmo Sorci et al. S100B inhibits myogenic differentiation and myotube formation in a RAGE-independent manner. 2003 |
| 217: | Ralf Benndorf et al. Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells. 2003 This publication discusses NOS3, KDR, AGTR1, and AGTR2. Reagent reviews based on this publication are available for phospho-eNOS, eNOS, Flk-1, AT1, and AT2. |
| 218: | Louis Ragolia et al. Prostaglandin D2 synthase inhibits the exaggerated growth phenotype of spontaneously hypertensive rat vascular smooth muscle cells. 2003 This publication discusses PTGDS, GSK3B, and MAPK1. Reagent reviews based on this publication are available for L-PGDS, Gsk3beta, and ERK. |
| 219: | Michael Coon et al. Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells. 2003 This publication discusses RPS6KA2, CASP3, FRAP1, CASP8, CASP9, CASP10, ZNF17, TNFRSF10A, PIK3CG, TNFRSF10B, MAPK3, RPS6KB1, MAPK1, AKT1, and CDC2. Reagent reviews based on this publication are available for p90RSK, Caspase 3, FRAP, Caspase 8, Caspase 9, Caspase 10, Wee1, DR4/TRAILR-1, PI3K inhibitor, DR5/TRAILR-2, Erk1, p70S6K, mTOR, Erk2, Akt, and Cdc2. |
| 220: | Helen S Goodridge et al. Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses. 2003 |
| 221: | SĂ©bastien Jeay et al. Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. 2003 |
| 222: | Marina Holgado-Madruga et al. Gab1 is an integrator of cell death versus cell survival signals in oxidative stress. 2003 |
| 223: | Bryan A Ballif et al. Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases. 2003 This publication discusses SRC, PIK3R1, PTPRO, and MAPK3. Reagent reviews based on this publication are available for Src, PI 3-kinase p85, phosphotyrosine, and ERK1. |
| 224: | Chih-Cheng Yang et al. Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells. 2003 This publication discusses BCL2L1, CYC1, AKT1, ACTB, and BAD. Reagent reviews based on this publication are available for Bcl-xL, cytochrome c, Akt, actin, and BAD. |
| 225: | Albert H Kim et al. JNK-interacting protein 1 promotes Akt1 activation. 2003 This publication discusses BAD and PIK3R2. Reagent reviews based on this publication are available for BAD(Ser-136) and p85. |
| 226: | Maria Chiara Deregibus et al. CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis. 2003 This publication discusses TRAF2, TRAF3, TRAF6, CD40, CBL, and PIK3R1. Reagent reviews based on this publication are available for TRAF2, TRAF3, TRAF6, CD40, c-Cbl, and p85 subunit of PI3-K. |
| 227: | Joseph J Senn et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. 2003 This publication discusses insulin receptor, ERBB3, and SOCS3. Reagent reviews based on this publication are available for IRS-1, p85, and SOCS-3. |
| 228: | Tracy Tzu-Ling Tang et al. The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism. 2003 This publication discusses HIF1A, TUBB, and VHL. Reagent reviews based on this publication are available for HIF-1alpha, beta-tubulin, and pVHL. |
| 229: | Yuichi Oike et al. Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. 2003 This publication discusses H3F3B, AKT1, and MAPK1. Reagent reviews based on this publication are available for phospho-histone H3, phospho-Akt, and phospho-p44/42 MAPK. |
| 230: | Byoung Moon et al. Resistin inhibits glucose uptake in L6 cells independently of changes in insulin signaling and GLUT4 translocation. 2003 |
| 231: | Madhavi J Rane et al. Heat shock protein 27 controls apoptosis by regulating Akt activation. 2003 This publication discusses HSPB1. Reagent reviews based on this publication are available for Hsp27 and phospho-Hsp27. |
| 232: | Ursula G B Haider et al. Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. 2003 This publication discusses AKT1, MAPK3, MAPK1, RPS6KB1, MAPK14, p53, CDKN1B, CDKN1A, and RB1. Reagent reviews based on this publication are available for Akt, Erk 1, Erk 2, p70S6k, p38 MAPK, p53, p27, p21, and retinoblastoma protein. |
| 233: | Michael Mildner et al. Hepatocyte growth factor/scatter factor inhibits UVB-induced apoptosis of human keratinocytes but not of keratinocyte-derived cell lines via the phosphatidylinositol 3-kinase/AKT pathway. 2002 This publication discusses DUSP4 and MET. Reagent reviews based on this publication are available for MAP kinase and c-met. |
| 234: | David J Kwiatkowski et al. A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. 2002 |
| 235: | Giuseppe Pandini et al. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. 2002 This publication discusses IGF1R, MAPK3, and insulin receptor. Reagent reviews based on this publication are available for IGF-IR alpha-subunit, IGF-IR alpha subunit, phospho-ERK1/2, and INSR. |
| 236: | Bernardo Yusta et al. Glucagon-like peptide-2 receptor activation engages bad and glycogen synthase kinase-3 in a protein kinase A-dependent manner and prevents apoptosis following inhibition of phosphatidylinositol 3-kinase. 2002 This publication discusses RPS6KA2, AKT1, RPS6KB1, MAPK1, GSK3A, GSK3B, BAD, and NFKBIA. Reagent reviews based on this publication are available for phospho-p90Rsk, phospho-Akt, phosphorylated p70 S6 kinase, phosphorylated p44/42 mitogen-activated protein kinase, phosphorylated GSK-3 alpha, phosphorylated GSK-3 beta, phospho-Bad ,Bad, and IkappaBalpha. |
| 237: | Henri H Versteeg et al. VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation. 2002 This publication discusses RPS6KA1, RPS6KB1, GSK3A, EEF1A1, and EIF4E. Reagent reviews based on this publication are available for phospho-p90RSK-Ser381, p90RSK, p70S6K, phospho-p70S6K, phospho-GSK3alpha /beta Ser21, GSK3alpha /beta, eEF1 alpha, and eIF-4E. |
| 238: | Jena J Steinle et al. Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway. 2002 This publication discusses EPHB4, EFNB2, MAPK1, MAPK3, and SRC. Reagent reviews based on this publication are available for Eph B4 receptor, ephrin B2, phospho-p42, phospho-p44, and phospho-Src. |
| 239: | Armelle Yart et al. A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. 2002 This publication discusses MAPK1, GRB2, PTPN11, EGFR, and GAB1. Reagent reviews based on this publication are available for phospho-Erk, Grb2, SHP2, EGFR, and Gab1. |
| 240: | David Decraene et al. Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes. 2002 This publication discusses PARP1 and MAPK14. Reagent reviews based on this publication are available for PARP and p38. |
| 241: | Dirk Haller et al. IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines. 2002 |
| 242: | Shyra Gardai et al. Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils. 2002 This publication discusses HLA-A, ITGAM, INPP5D, LYN, FAS, and ITGB2. Reagent reviews based on this publication are available for HLA-ABC W6/32, alphaM VIM12, SHIP, Lyn, Fas, and CD18. |
| 243: | Madhu Mawal-Dewan et al. Regulation of collagenase expression during replicative senescence in human fibroblasts by Akt-forkhead signaling. 2002 |
| 244: | Makoto Hashimoto et al. Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection. 2002 |
| 245: | Christopher J Howe et al. Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytes. 2002 This publication discusses ATP8A2, EPHB1, and CHUK. Reagent reviews based on this publication are available for IkappaB, phospho-ERK, and phospho-IKK. |
| 246: | Thomas Jahn et al. Role for the adaptor protein Grb10 in the activation of Akt. 2002 This publication discusses KIT, PIK3CG, MAPK11, and GRB10. Reagent reviews based on this publication are available for c-kit, PI3-K, phospho p44/42 MAPK, and Grb10. |
| 247: | Veronique Béréziat et al. Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14. 2002 This publication discusses insulin receptor, MAPK3, MAPK1, and PTPN1. Reagent reviews based on this publication are available for IR beta-subunit, phosphorylated ERK1/2, ERK1/2, and PTP1B. |
| 248: | Robert C Rintoul et al. Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth. 2002 This publication discusses SLC3A2, transferrin receptor, PIK3R1, PTK2, and ITGB1. Reagent reviews based on this publication are available for 4F2, CD71, p85alpha PI 3-kinase, FAK and phospho FAK, CD98, and beta1 integrin. |
| 249: | Ming-Hui Zou et al. Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase. 2002 This publication discusses NOS3, NOSIP, PRKAA1, PRKAB1, and ACACA. Reagent reviews based on this publication are available for eNOS, phosphor-eNOS, phospho-AMPK, AMPK, and phospho-ACC. |
| 250: | Patrick A Kiely et al. RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death. 2002 This publication discusses insulin receptor, MAPK1, and IGF1R. Reagent reviews based on this publication are available for IR, Erk2, p42/44 MAP kinase, and IGF-1R. |
| 251: | Susan Kane et al. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. 2002 |
| 252: | Gieri Camenisch et al. ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo. 2002 This publication discusses ITGA5, ITGAV, ITGB5, MAPK3, and PTK2. Reagent reviews based on this publication are available for integrin alpha5beta1, integrin alphavbeta3, integrin alphavbeta5, p42/44 MAPK, and FAK. |
| 253: | C J Grill et al. Constitutive expression of IGF-binding protein-3 by mammary epithelial cells alters signaling through Akt and p70S6 kinase. 2002 This publication discusses RPS6KB1 and MAPK1. Reagent reviews based on this publication are available for p70S6K and ERK1/2. |
| 254: | Duncan Howie et al. The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. 2002 This publication discusses SLAMF1, MAPK1, and MAPK3. Reagent reviews based on this publication are available for CD150, ERK, and ERK1/2. |
| 255: | Dennis R Chesire et al. In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis. 2002 This publication discusses androgen receptor, CTNNBL1, prostate specific antigen, TCF4, CREBBP, and AKT1. Reagent reviews based on this publication are available for AR, beta-catenin, PSA, TCF4, CBP, and Akt. |
| 256: | Hideki Murakami et al. Role of Dok1 in cell signaling mediated by RET tyrosine kinase. 2002 This publication discusses AKT1, NCK1, RASA1, DOK1, MAPK3, MAPK1, MAPK8, and galectin 4. Reagent reviews based on this publication are available for Akt and phosphoAkt, Nck, Ras-GAP, Dok1, Erk1, Erk2, JNK, GAL4 DNA-binding domain, phosphoErk1, phosphoErk2, and stress-activated protein kinase/JNK. |
| 257: | Anjana Saxena et al. Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1. 2002 |
| 258: | Heidi L Kenerson et al. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. 2002 This publication discusses RPS6KB1, FRAP1, RPS6, EIF4EBP1, CDKN1B, cyclin D1, TSC2, and PCNA. Reagent reviews based on this publication are available for phospho-p70S6K, phospho-mTOR, phospho-S6, PHAS-I (4E-BP1), Kip1 (p27), cyclin D1, tuberin, and PCNA. |
| 259: | Eun Sook Hwang et al. An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines. 2002 |
| 260: | Shazli N Malik et al. Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. 2002 This publication discusses MAPK1 and MAPK3. Reagent reviews based on this publication are available for phospho-p44/42 MAP kinase and Erk1. |
| 261: | Diana Birle et al. Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation. 2002 This publication discusses PTEN. Reagent reviews based on this publication are available for phospho-PTEN. |
| 262: | Mihail S Iordanov et al. The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor. 2002 This publication discusses AMY 1, p53, SHC1, TP63, ECM1, MAPK8, GRB2, MAPK1, KRAS, EPHB1, SOS1, MAPK3, FOXO1, MAP2K2, cyclin D1, and EGFR. Reagent reviews based on this publication are available for c-Myc, p53, ShcA, p63, phospho-p85, phospho-JNK, Grb2, phospho-p38 MAPK, Ras, phospho-ERK, Sos1, ERK1/ERK2, phospho-FKHR, MEK2, cyclin D1, and EGFR. |
| 263: | Jianguo Gu et al. Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways. 2002 This publication discusses MAP2K1, MAPK3, MAPK1, and PTK2. Reagent reviews based on this publication are available for MEK1, ERK1, ERK2, and FAK. |
| 264: | Fei Su et al. WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. 2002 This publication discusses WISP1, p53, CASP3, PARP1, RAN, CDKN1A, GSK3B, AKT1, BCL2L1, and FAS. Reagent reviews based on this publication are available for WISP-1, p53, caspase-3, PARP, Ran, p21, GSK3beta, Akt, Bcl-XL, and Fas. |
| 265: | Hong Wang et al. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice. 2002 This publication discusses PTEN. Reagent reviews based on this publication are available for Pten. |
| 266: | Russell D Klein et al. Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. 2002 This publication discusses IGF1R, GSK3A, and cyclin D1. Reagent reviews based on this publication are available for IGFR-1, phosho-GSK-3, and Cyclin D1. |
| 267: | Hiroyuki Sano et al. Insulin receptor substrate 4 associates with the protein IRAS. 2002 This publication discusses PIK3CA, GRB2, AKT2, IRS1, MAPK3, MAPK1, and IRS2. Reagent reviews based on this publication are available for PI 3-kinase, Grb2, Akt2, IRS-1, ERK1, ERK2, and IRS-2. |
| 268: | Janice C Wolfman et al. Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38. 2002 |
| 269: | Marie Stahl et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. 2002 This publication discusses BCL2L11 and FOXO4. Reagent reviews based on this publication are available for Bim and FoxO4. |
| 270: | Maria Chiara Deregibus et al. HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells. 2002 This publication discusses AKT1, FLT1, BAD, KDR, IGF1, IGF1R, IL3, MCAM, desmin, and SMC1A. Reagent reviews based on this publication are available for AKT, VEGFR1, BAD, VEGFR2, AKT1, IGF-I, IGF-IR, IL-3, P1H12, desmin D33, and SMC. |
| 271: | JoAnne S Richards et al. Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins. 2002 This publication discusses FOXO1, PDGFRB, SLC2A1, IRS2, FOXO3, and SGK1. Reagent reviews based on this publication are available for FKHR, IGF-1Rbeta, Glut-1, IRS-2, FKHRL1, and Sgk. |
| 272: | Wei Liu et al. Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways. 2002 This publication discusses MIB1, thyroglobulin, PTEN, SKP2, and CDKN1B. Reagent reviews based on this publication are available for MIB-1, thyroglobulin, PTEN, Skp2, and p27. |
| 273: | Toshifumi Fukuda et al. Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase. 2002 This publication discusses MAPK1, PRKAR2A, and AKAP5. Reagent reviews based on this publication are available for phospho-ERK, PKA-RII, and AKAP79. |
| 274: | Saori Sato et al. Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3. 2002 This publication discusses PDK1, RAF1, YWHAZ, and SGK1. Reagent reviews based on this publication are available for PDK1, Raf-1, 14-3-3 theta, and phospho-SGK. |
| 275: | Shafiq A Khan et al. Follicle-stimulating hormone amplifies insulin-like growth factor I-mediated activation of AKT/protein kinase B signaling in immature rat Sertoli cells. 2002 This publication discusses CREB. Reagent reviews based on this publication are available for CREB. |
| 276: | Bhumsoo Kim et al. Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt. 2002 This publication discusses ITGB1, AKT1, MAP3K1, CASP9, and PTK2. Reagent reviews based on this publication are available for integrin beta1, Akt, MAPK, caspase-9, and FAK. |
| 277: | M J Wick et al. Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt. 2001 |
| 278: | H Han et al. Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases. 2001 |
| 279: | X Chen et al. Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase. 2001 This publication discusses RASA1, RAB5A, RABEP1, and EGFR. Reagent reviews based on this publication are available for p120 Ras GAP, Rab5, Rabaptin5, and EGFR. |
| 280: | S Fan et al. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair. 2001 This publication discusses PIK3R1, PIK3CA, AKT1, FOXO1, MET, and GAB1. Reagent reviews based on this publication are available for p85 (PI3K regulatory subunit), p110 (PI3K catalytic subunit), c-Akt, FKHR, c-Met, and Gab1. |
| 281: | M Zang et al. Microtubule integrity regulates Pak leading to Ras-independent activation of Raf-1. insights into mechanisms of Raf-1 activation. 2001 This publication discusses RAF1 and MAPK1. Reagent reviews based on this publication are available for Raf-1, Raf-1 phospho-Ser338, and phospho-MAPK (Erk1/2) and MAPK. |
| 282: | K Hisamoto et al. Estrogen induces the Akt-dependent activation of endothelial nitric-oxide synthase in vascular endothelial cells. 2001 |
| 283: | K Yu et al. mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer. 2001 This publication discusses AKT1, RPS6KB1, EIF4EBP1, CCND3, CDKN1B, and FOXO3. Reagent reviews based on this publication are available for AKT, p70 S6 kinase, phospho-4E-BP1 (Thr-37, Thr-46 and Ser-65), cyclin D3, 4E-BP1, p27kip1, and phospho-FKHRL-1 (Thr32). |
| 284: | Y Sasaki et al. Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1. 2001 This publication discusses MAP2K4 and MAP3K7. Reagent reviews based on this publication are available for MEK4/SEK1, TAK1, and phospho-SEK1 (Thr223). |
| 285: | E Avota et al. Disruption of Akt kinase activation is important for immunosuppression induced by measles virus. 2001 This publication discusses IL2RA, GSK3B, BAD, JAK1, JAK3, STAT3, and STAT5B. Reagent reviews based on this publication are available for IL-2R, GSK-3beta, BAD, JAK1, JAK3, STAT3, and STAT5b. |
| 286: | T Wada et al. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity. 2001 This publication discusses PIK3R1, IRS1, GSK3B, GLUT4, SLC2A1, and transferrin receptor. Reagent reviews based on this publication are available for PI 3-kinase p85 subunit, IRS1, Ser21 and Ser9 phospho-specific GSK3, Glut4, GSK3, Glut1, and transferrin receptor. |
| 287: | H Huang et al. PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression. 2001 This publication discusses PTEN, BCL2L1, MAPK1, AKT1, and CREB. Reagent reviews based on this publication are available for PTEN, Bcl-XL, extracellular signal-regulated kinase 2, Akt, and CREB. |
| 288: | C Sweeney et al. Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors. 2001 This publication discusses AKT1, EGFR, RPS6KB1, ERBB2, RPS6KA1, ERBB3, PRKCA, ERBB4, JUN, GRB2, CBL, CREB, SHC1, PTPN11, MAPK3, and MAPK1. Reagent reviews based on this publication are available for Akt, EGFR, p70S6k, ErbB2, p90Rsk, ErbB3, PKC, ErbB4, Jun, Grb2, Cbl, CREB, Shc, SHP2, Erk1, and Erk2. |
| 289: | M J Rane et al. p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. 2001 This publication discusses AKT2, AKT3, MAPK14, and MAPKAPK2. Reagent reviews based on this publication are available for Akt2, Akt3, p38, phospho-p38, and MK2. |
| 290: | I Fleming et al. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. 2001 This publication discusses NOS3, MAPK3, and MAPK1. Reagent reviews based on this publication are available for phospho-eNOS, Erk1 and phosphor-Erk1, Erk2 and phosphor-Erk2, and eNOS. |
| 291: | A L Sirén et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. 2001 This publication discusses erythropoietin receptor, MAPK3, and STAT5A. Reagent reviews based on this publication are available for EPOR, phospho-p44/42 MAPK (Thr-202/Tyr-204), phospho-Stat5 (Tyr-694), and Stat5. |
| 292: | R A Campbell et al. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. 2001 This publication discusses cyclin D1, PTEN, BCL2L1, BAX, BAK1, PIK3CG, PIK3R1, AKT1, and ESR1. Reagent reviews based on this publication are available for cyclin D1, PTEN, Bcl-XL, BAX, BAK, PI3K-p110, p85, AKT, and ER. |
| 293: | N J Hellyer et al. Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor. 2001 This publication discusses SHC1, PIK3R1, and PIK3CA. Reagent reviews based on this publication are available for Shc, p85, and p110. |
| 294: | E Asselin et al. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells. 2001 |
| 295: | D C Otero et al. Cd19-dependent activation of Akt kinase in B-lymphocytes. 2001 |
| 296: | J M Paramio et al. Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest. 2001 This publication discusses PRKCZ. Reagent reviews based on this publication are available for PKC zeta. |
| 297: | C Jiang et al. Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. 2001 This publication discusses PARP1, CASP1, MAPK8, MAPK14, and CYC1. Reagent reviews based on this publication are available for PARP, caspases, JNK, p38 MAPK, and cytochrome C. |