| gene | reagent | sample publication | sample review |
IL1A
interleukin 1, alpha | | total:15
CD28 co-stimulation down regulates th17 development. 2009 to the paper
| R&D Systems recombinant mouse IL-1 was used to treat the cells in order to identify the importance of B7 co-stimulatory molecules in the negative regulation of Th17 development more |
IL-1β
interleukin 1, beta | | total:66
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function. 2009 to the paper
| R&D Systems ELISA kit for IL-1? was used to detect IL-1? level in order to study the role for interferon-? induced enhancement of toll-like receptor expression and function in malaria primes the innate immune response. more |
IL1F5
interleukin 1 family, member 5 (delta) | | | |
IL1F6
interleukin 1 family, member 6 (epsilon) | | | |
IL1F7
interleukin 1 family, member 7 (zeta) | | total:1
Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. 2003 to the paper
| GlaxoSmithKline rabbit anti-IL-1H4 polyclonal antibody was used in western blot to study the role played by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) in the link between innate and adaptive immunity.
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IL1F8
interleukin 1 family, member 8 (eta) | | | |
IL1F9
interleukin 1 family, member 9 | | | |
IL1F10
interleukin 1 family, member 10 (theta) | | | |
IL1R1
interleukin 1 receptor, type I | | total:6
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
| R&D Systems polyclonal goat anti-human IL1R1 antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more |
IL1R2
interleukin 1 receptor, type II | | total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
| R&D Systems polyclonal goat anti-human IL1R2 antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more |
IL1RAP
interleukin 1 receptor accessory protein | | total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
| R&D Systems polyclonal goat anti-human IL1RAcP antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more |
IL1RAPL1
interleukin 1 receptor accessory protein-like 1 | | total:1
A human protein atlas based on antibody proteomics. 2006 to the paper
| Sigma IL1RAPL1 antibody was tested in immunohistochemistry by Human Protein Atlas
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IL1RAPL2
interleukin 1 receptor accessory protein-like 2 | | | |
ST2
interleukin 1 receptor-like 1 | | total:4
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. 2009 to the paper
| Sigma IL1RL1 antibody was used in immunohistochemistry to study the distinctive differences at the molecular level between deceased donor (DD) and living donor (LD) liver grafts more |
IL1RL2
interleukin 1 receptor-like 2 | | | |
IL1RN
interleukin 1 receptor antagonist | | total:3
A human protein atlas based on antibody proteomics. 2006 to the paper
| Sigma IL1RN antibody was tested in immunohistochemistry by Human Protein Atlas more |
| interleukin 2 | | total:36
Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses. 2009 to the paper
| R&D Systems ELISA kit for IL-2 was used to measure IL2 level in order to define the role of DPP-IV in the immune system more |
CD25
interleukin 2 receptor, alpha | | total:78
Characterization of the thymic IL-7 niche in vivo. 2009 to the paper
| eBiosciences anti-CD25 antibody was used to perform flow cytometry in order to show thymic IL-7 levels in vivo is regulated by the physiological conditions. more |
IL2RB
interleukin 2 receptor, beta | | total:6
CCR2 receptor is essential to activate microbicidal mechanisms to control Toxoplasma gondii infection in the central nervous system. 2008 to the paper
| BD Bioscience OpTEIA ELISA kit for IL-12p70 was used to measure the concentration of IL-12p70 in the serum samples and intestinal homogenates in order to study the role of the chemokine receptor CCR2 in T. gondii infection. more |
IL2RG
interleukin 2 receptor, gamma (severe combined immunodeficiency) | | total:3
Characterization of the interleukin-4 receptor complex in human corneal fibroblasts. 2002 to the paper
| Sumitomo Electric rat monoclonal anti-IL-2Rgammac antibody was used in western blot to study the role of the interleukin (IL) -4 receptor (IL-4R) complex in human corneal fibroblasts. more |
IL3
interleukin 3 (colony-stimulating factor, multiple) | | total:3
Evidence for a lectin activity for human interleukin 3 and modeling of its carbohydrate recognition domain. 2002 to the paper
| Chemicon polyclonal antibody to IL-3 was used in western blot to study the specific binding of human interleukin 3 to a chondroitin sulfate proteoglycan isolated from adult rat brain and the modeling of its carbohydrate recognition domain (CRD) .
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CD123
interleukin 3 receptor, alpha (low affinity) | | total:9
A human protein atlas based on antibody proteomics. 2006 to the paper
| Sigma IL3RA antibody was tested in immunohistochemistry by Human Protein Atlas more |
IL-4
interleukin 4 | | total:54
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
| Invitrogen anti-IL-4 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more |
IL4R
interleukin 4 receptor | | total:8
IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis. 2009 to the paper
| BD anti-CD124 antibody was used to perform flow cytometry in order to study the role aaMph play in preventing uncontrolled cerebral cryptococcosis. more |
interleukin 5
interleukin 5 (colony-stimulating factor, eosinophil) | | total:18
IL-33 exacerbates antigen-induced arthritis by activating mast cells. 2008 to the paper
| BD PharMingen anti-IL-5 antibody was used in ELISA to study the role of the effect of IL-33 on mast cells in antigen-induced arthritis. more |
IL5RA
interleukin 5 receptor, alpha | | total:2
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge. 2002 to the paper
| R&D Systems polyclonal biotinylated goat anti-human IL-5Rα antibody was used in ELISA to study the expression of membrane IL-5 receptor on human eosinophils. more |
IL-6
interleukin 6 (interferon, beta 2) | | total:101
Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. 2010 to the paper
| BD Biosciences anti-IL-6 antibody was used in flow cytometry in order to study the role of conventional DCs (cDCs) in liver ischemia/reperfusion (I/R) injury in mice. more |
IL-6R
interleukin 6 receptor | | total:13
Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. 2009 to the paper
| BD Biosciences anti-IL-6R alpha antibody was used for flow cytometry in order to show that interleukin-6 controls lymphopoiesis and affects production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa mice. more |
gp130
interleukin 6 signal transducer (gp130, oncostatin M receptor) | | total:14
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
| BD Biosciences anti-gp130 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more |
IL-7
interleukin 7 | | total:9
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
| BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more |
IL7R
interleukin 7 receptor | | total:11
Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. 2009 to the paper
| BD PharMingen anti-CD127 antibody was used for flow cytometry in order to show that interleukin-6 controls lymphopoiesis and affects production of myeloid cells in systemic lupus erythematosus?Cprone B6.Sle1.Yaa mice. more |
IL-8
interleukin 8 | | total:56
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. 2009 to the paper
| Epitomics IL-8 antibody was used in immunohistochemistry to study the distinctive differences at the molecular level between deceased donor (DD) and living donor (LD) liver grafts more |
CXCR1
chemokine (C-X-C motif) receptor 1 | | total:7
CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis. 2005 to the paper
| R&D Systems CXCR1 antibody(1:100) was used in immunohistochemistry to study the expression of CXC chemokine receptors on human oligodendrocytes. more |
CXCR2
chemokine (C-X-C motif) receptor 2 | | total:10
Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1. 2009 to the paper
| R&D Systems anti-CXCR2 antibody was used for immunohistochemistry in order to suggest that CXCL1 can regulate autoimmune demyelination in mice. more |
IL9
interleukin 9 | | | |
IL9R
interleukin 9 receptor | | | |
IL-10
interleukin 10 | | total:49
Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. 2010 to the paper
| BD Biosciences anti-IL-10 antibody was used in flow cytometry in order to study the role of conventional DCs (cDCs) in liver ischemia/reperfusion (I/R) injury in mice. more |
IL10RA
interleukin 10 receptor, alpha | | total:5
Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion. 2010 to the paper
| BD Biosciences anti- IL-10R antibody was used in flow cytometry in order to study the role of conventional DCs (cDCs) in liver ischemia/reperfusion (I/R) injury in mice. more |
IL10RB
interleukin 10 receptor, beta | | | |
IL-11
interleukin 11 | | total:6
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. 2009 to the paper
| Genetics Institute IL-11 was used to activate the CD4+ T cells in order to demonstrate IL-6 promotes antibody production through increased IL-21 production. more |
IL11RA
interleukin 11 receptor, alpha | | total:4
A human protein atlas based on antibody proteomics. 2006 to the paper
| Sigma IL11RA antibody was tested in immunohistochemistry by Human Protein Atlas more |
IL11RB
interleukin 11 receptor, beta | | |
IL-12
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | | total:26
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function. 2009 to the paper
| Becton-Dickinson CBA inflammation kit for IL12p70 was used to detect IL12p70 level in order to study the role for interferon-? induced enhancement of toll-like receptor expression and function in malaria primes the innate immune response. more |
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | | total:16
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function. 2009 to the paper
| R&D Systems ELISA kit for IL12p40 was used to detect IL12p40 level in order to study the role for interferon-? induced enhancement of toll-like receptor expression and function in malaria primes the innate immune response. more |
IL12RB1
interleukin 12 receptor, beta 1 | | total:5
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. 2009 to the paper
| R&D Systems IL-12 was used to activate the CD4+ T cells in order to demonstrate IL-6 promotes antibody production through increased IL-21 production. more |
IL12RB2
interleukin 12 receptor, beta 2 | | total:1
Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells. 2004 to the paper
| BD Biosciences mouse monoclonal anti-IL12Rβ2 antibody was used in western blot to study the activation of STAT4 signaling in human vascular endothelial cells by interferon α .
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IL-13
interleukin 13 | | total:17
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. 2010 to the paper
| R&D Systems Mouse recombinant IL-13 was used to treat peritoneal macrophages in order to investigate the effect of interleukin-4 treatment on phagocytosis of pathogens and cytokine secretion in macrophages. more |
IL13RA1
interleukin 13 receptor, alpha 1 | | total:3
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts. 2006 to the paper
| R&D Systems anti-PEDF antibody was used in immunohistochemistry to study the role for interleukin-13 in obstructive lesion development. more |
IL13RA2
interleukin 13 receptor, alpha 2 | | total:4
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. 2008 to the paper
| R&D goat anti-human IL-13Rα2 polyclonal antibody(15 μg/ml) was used in immunohistochemistry in order to investigate the protein expression of three glioma-associated antigens (GAAs) in pediatric brain stem glioma (BSG) and non-brain stem glioma (NBSG) cases more |
IL 15
interleukin 15 | | total:16
Interleukin-15 and NK1.1+ cells provide innate protection against acute Salmonella enterica serovar Typhimurium infection in the gut and in systemic tissues. 2009 to the paper
| R&D Systems anti-IL-15 antibody was used to perform ELISA in order to show that interleukin-15 and NK1.1+ Cells are critical components of the innate immune defense against acute salmonella enterica serovar typhimurium infection in the gut and in systemic tissues. more |
IL15RA
interleukin 15 receptor, alpha | | total:1
Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. 2003 to the paper
| Santa Cruz Biotechnology anti-IL-15R polyclonal antibody (clone H-107) was used in immunohistochemistry, blocking experiment and western blot to study the production of interleukin 15 by human colon cancer cells associated with induction of mucosal hyperplasia, angiogenesis, and metastasis.
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IL15RB
interleukin 15 receptor, beta | | |
IL16
interleukin 16 (lymphocyte chemoattractant factor) | | | |
IL-17
interleukin 17A | | total:30
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. 2009 to the paper
| R&D Systems anti?CIL-17A was used for neutralization in order to study the function of CD161+ cells that can be activated by IL-23 and mediate destructive tissue inflammation. more |
IL 17B
interleukin 17B | | | |
IL 17C
interleukin 17C | | | |
IL17D
interleukin 17D | | | |
IL 17F
interleukin 17F | | | |
IL17RA
interleukin 17 receptor A | | total:1
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. 2007 to the paper
| Santa Cruz Biotechnology IL-17RA antibody was used in western blot to study the essential involvement of the adaptor protein Act1 in IL-17 receptor (IL-17R) signaling and IL-17-dependent immune responses.
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IL17RB
interleukin 17 receptor B | | | |
interleukin 17 receptor like
interleukin 17 receptor C | | | |
IL17RD
interleukin 17 receptor D | | | |
IL17RE
interleukin 17 receptor E | | | |
interleukin 18
interleukin 18 (interferon-gamma-inducing factor) | | total:10
Anti-inflammatory effect of pigment epithelium-derived factor in DBA/2J mice. 2009 to the paper
| Millipore anti-IL-18 antibody was used to perform western blot in order to show that the pigment epithelium-derived factor can reduce inflammation. more |
IL18BP
interleukin 18 binding protein | | total:1
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
| Peprotech recombinant IL-18BP was used to treat cells in order to study the role for IL-32 in the effect of IL-1? on endothelial cell functions.
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IL18R1
interleukin 18 receptor 1 | | total:1
Enhanced expression of interleukin-18 and its receptor in idiopathic pulmonary fibrosis. 2004 to the paper
| PharMingen anti human IL-18Ralpha mAb (H44) antibody was used in immunohistochemistry to study interleukin-18 and its receptor in idiopathic pulmonary fibrosis
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IL18RAP
interleukin 18 receptor accessory protein | | | |
IL19
interleukin 19 | | total:1
Expression and suppressive effects of interleukin-19 on vascular smooth muscle cell pathophysiology and development of intimal hyperplasia. 2008 to the paper
| R&D Systems anti-IL19 anibody was used in western blot in order to demonstrate that IL-19 can be induced by inflammatory cytokines and inflammatory stimuli
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IL20
interleukin 20 | | | |
IL20RA
interleukin 20 receptor, alpha | | | |
IL20RB
interleukin 20 receptor beta | | | |
IL 21
interleukin 21 | | total:7
Follicular helper T cells are required for systemic autoimmunity. 2009 to the paper
| R&D Systems goat anti-mouse IL-21 antibody was used to carry out ELISA assay in order to investigate the effect for aberrant positive selection of follicular helper T cell on systemic autoimmunity. more |
IL21R
interleukin 21 receptor | | total:2
Follicular helper T cells are required for systemic autoimmunity. 2009 to the paper
| R&D Systems recombinant mouse IL-21R Fc fusion protein was used to carry out ELISA assay in order to investigate the effect for aberrant positive selection of follicular helper T cell on systemic autoimmunity. more |
IL 22
interleukin 22 | | total:3
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. 2009 to the paper
| Antigenix America mouse IL-22 ELISA construction kit was used to perform ELISA in order to show that lymphoid tissue inducer?Clike cells can produce IL-17 and IL-22. more |
IL22RA1
interleukin 22 receptor, alpha 1 | | | |
IL22RA2
interleukin 22 receptor, alpha 2 | | total:1
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. 2009 to the paper
| R&D Systems anti?CIL-22BP was used for neutralization in order to study the function of CD161+ cells that can be activated by IL-23 and mediate destructive tissue inflammation.
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IL 23
interleukin 23, alpha subunit p19 | | total:9
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. 2009 to the paper
| Cell Signaling anti-p19 antibody was used to perform western blot in order to study the regulation of NANOG in G1 to S transition in human embryonic stem cells. more |
MDA-7
interleukin 24 | | total:5
A human protein atlas based on antibody proteomics. 2006 to the paper
| Sigma IL24 antibody was tested in immunohistochemistry by Human Protein Atlas more |
IL 17E
interleukin 25 | | | |
IL26
interleukin 26 | | | |
IL27
interleukin 27 | | total:1
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. 2008 to the paper
| R&D systems anti-IL-27p28 antibody(BAF1834) was used in ELISA to study the effect of engagement of the type-I interferon receptor on on dendritic cells on T helper 17 cell development.
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IL27RA
interleukin 27 receptor, alpha | | | |
IL28A
interleukin 28A (interferon, lambda 2) | | | |
IL28B
interleukin 28B (interferon, lambda 3) | | | |
IL28RA
interleukin 28 receptor, alpha (interferon, lambda receptor) | | | |
IL 29
interleukin 29 (interferon, lambda 1) | | | |
IL 31
interleukin 31 | | | |
IL31RA
interleukin 31 receptor A | | total:1
Cardiotrophin-1 stimulation of cardiac fibroblast growth: roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor. 2002 to the paper
| Santa Cruz Biotechnology rabbit polyclonal gp130 antibody was used in western blot and immunocytochemistry to study cardiotrophin-1 effect on cardiac fibroblast growth
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IL32
interleukin 32 | | total:2
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
| R&D Systems anti-human IL-32 was used in western blot in order to study the role for IL-32 in the effect of IL-1? on endothelial cell functions. more |
