Interleukin and interleukin receptor
gene
reagent
sample publication
sample review
total:5
Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. 2006 to the paper
R & D Systems monoclonal anti-human IL-1alpha antibody was used in human SSc fibroblasts and in immunocytochemistry, immunoprecipitation to study the effect of intracellular IL-1alpha-binding proteins on biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts. more
total:28
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
R&D Systems anti-human IL-1 was used in western blot in order to study the role for IL-32 in the effect of IL-1 on endothelial cell functions. more
total:1
Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. 2003 to the paper
GlaxoSmithKline rabbit anti-IL-1H4 polyclonal antibody was used in western blot to study the role played by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) in the link between innate and adaptive immunity.
total:5
Control of chemokine gradients by the retinal pigment epithelium. 2008 to the paper
Abcam IL-1R1 antibody was used in western blot in order to examine the physiological responses of human fetal retinal pigment epithelia (hfRPE) after polarized activation of proinflammatory cytokine receptors in vitro more
total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
R&D Systems polyclonal goat anti-human IL1R2 antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more
total:2
Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology. 2007 to the paper
R&D Systems polyclonal goat anti-human IL1RAcP antibody was used in western blot and immunocytochemistry to evaluate the role of IL1R2 deficiency in endometriosis pathophysiology. more
total:3
IL-33 mediates inflammatory responses in human lung tissue cells. 2010 to the paper
R&D Systems anti-ST2/IL1R4 antibody was used in western blot to study the role of IL-33 in inflammatory responses in human lung tissue cells. more
total:1
Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. 2006 to the paper
R&D Systems IL-1RA ELISA ket was used to study inflammatory response induced by glucan
total:15
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. 2011 to the paper
BD Pharmingen anti-IL-2 was used to perform flow cytometry in order to show that Pf sporozoites specific CD8+ could be induced by live attenuated malaria vaccine. more
total:44
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. 2009 to the paper
eBioscience anti-CD25 antibody was used in flow cytometry in order to investigate the role of dendritic cells in the regulation of spontaneous fatal autoimmunity. more
total:3
Interleukin-2 and its receptor complex (alpha, beta and gamma chains) in in situ and infiltrative human breast cancer: an immunohistochemical comparative study. 2004 to the paper
Santa Cruz Biotechnology rabbit anti-human IL-2R beta antibody was used in immunohistochemistry to study its expression in human breast cancer more
total:5
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
BD Bioscience CD132 antibody was used to perform flow cytometry in order to identify that IL-13 is an effector cytokine and IL-4 is an immunoregulatory cytokine. more
total:4
Covering a broad dynamic range: information processing at the erythropoietin receptor. 2010 to the paper
R&D Systems anti-IL3 antibody was used to carry out immunoprecipitation assay and western blot analysis in order to determine the receptor property of erythropoietin receptor during receptor signaling activation. more
total:12
A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. 2010 to the paper
eBiosciences anti-CD123 antibody was
used to perform immunocytochemistry and flow cytometry in order to show that mesenchymal stem cell can be polarized by downstream TLR signaling into two distinctly acting phenotypes. more
total:18
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
R&D Systems anti-IL-4 was used in 5ug/ml to perform cell stimulation in order to show that blood-brain barrier integrity and CNS immune quiescence was promoted by Sonic hedgehog pathway. more
total:5
Characterization of the interleukin-4 receptor complex in human corneal fibroblasts. 2002 to the paper
R&D Systems neutralizing mouse monoclonal anti-IL4R antibody was used in ELISA to study the role of the interleukin (IL) 4 receptor (IL-4R) complex in human corneal fibroblasts. more
total:8
Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and FcepsilonRI. 2003 to the paper
R&D Systems IL-5 ELISA kit was used in immunocytochemistry to study TLR4- and Fc{epsilon}RI mediated gene expression in human mast cells more
total:2
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge. 2002 to the paper
R&D Systems polyclonal biotinylated goat anti-human IL-5Ralpha antibody was used in ELISA to study the expression of membrane IL-5 receptor on human eosinophils. more
total:41
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL6 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and
anabolic machinery in facilitating the synthesis of secretory proteins. more
total:10
Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. 2009 to the paper
Santa Cruz Biotechnology anti-gp80 antibody was used in western blot in order to study the role of vIL-6 in the growth and survival of cells latently infected with HHV-8. more
total:11
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours. 2009 to the paper
Santa Cruz Biotechnology monoclonal anti-gp130 antibody (C-20) was used in western blot and immunohistochemistry to study the role for activated gp130 in inflammatory hepatocellular tumours. more
total:3
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors. 2009 to the paper
BD Pharmingen anti-IL7-R antibody was used in flow cytometry in order to investigate the role of MOZ in the regulation of the proliferation of hematopoietic precursors. more
total:5
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. 2011 to the paper
Immunotech anti-CDw127 was used to perform PCR in order to show that CFS patients do not have murine-like gammaretroviruses in their blood. more
total:46
Spatial coupling of mTOR and autophagy augments secretory phenotypes. 2011 to the paper
R&D systems anti-IL8 antibody was used to perform immunocytochemistry in order to study the role of spatial coupling of cells' catabolic and
anabolic machinery in facilitating the synthesis of secretory proteins. more
total:7
Short-term heat exposure inhibits inflammation by abrogating recruitment of and nuclear factor-{kappa}B activation in neutrophils exposed to chemotactic cytokines. 2008 to the paper
Santa Cruz IL-8-receptor antibody was used in western blot in order to test the hypothesis that exposure of mice to fever-like temperatures abrogates neutrophil recruitment and NF-kappaB activation in a mouse model of skin inflammation more
total:9
The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. 2008 to the paper
R&D Systems CXCR2 IgG2a antbody was used to inhibit cell adhesion in order to study the role of the chemokines MCP-1, GRO-alpha, IL-8, and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques more
total:20
Identification of IL-17-producing FOXP3+ regulatory T cells in humans. 2009 to the paper
R&D Systems IL-10 ELISA kit was used to perform ELISA in order to confirm that IL-17+FOXP3+ Treg cells were generated in the periphery. more
total:2
Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1. 2004 to the paper
BD Pharmingen monoclonal IL-10R1 antibody (3F9) was used in blocking experiment to block the binding of IL-10 to the IL-10 receptor in human pulmonary adenocarcinoma NCI-H441 cells. more
total:4
Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window. 2007 to the paper
Dr Lorraine Robb (the Walter and Eliza Hall Institute of Medical Research) mouse anti-huIL-11 (clone 5E3) antibody was used in immunohistochemistry to study the expression of phosphorylated STAT3, interleukin 11, and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window more
total:3
Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. 2006 to the paper
Santa Cruz Biotechnology IL-11R (1:10) antibody was used in immunohistochemistry to study the mechanisms that regulate oligodendrocyte survival and myelin formation. more
total:9
Immunologic testing of xeno-derived osteochondral grafts using peripheral blood mononuclear cells from healthy human donors. 2005 to the paper
BD Pharmingen anti-IL-12 and biotinylated anti-IL-12 antibodies were used in ELISPOT assay to evaluate the production of IL-12 by human monocytes in response to the antigens. more
total:2
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-12 (p40) antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:4
A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors. 2004 to the paper
R&D Systems anti-human IL-12Rbeta1 mAb (clone 69310 coupled to R-phycoerythrin) was used in flow cytometry to molecularly investigate a patient with a novel form of complete IL-12Rbeta1 deficiency despite the presence of IL-12Rbeta1 at the cell surface. more
total:1
Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells. 2004 to the paper
BD Biosciences mouse monoclonal anti-IL12Rbeta2 antibody was used in western blot to study the activation of STAT4 signaling in human vascular endothelial cells by interferon alpha.
total:9
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. 2008 to the paper
R&D Systems anti-IL-13 antibody was used to perform immunocytochemistry in order to study the pathogenesis of chronic lung disease. more
total:3
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. 2008 to the paper
R&D Systems anti-IL-13Ralpha1 antibody was used for flow cytometry to elucidated the role of IL-4 and IL-13 in regulates relative cytokine sensitivity. more
total:5
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. 2008 to the paper
R&D goat anti-human IL-13Ralpha2 polyclonal antibody (15 ug/ml) was used in immunohistochemistry in order to investigate the protein expression of three glioma-associated antigens (GAAs) in pediatric brain stem glioma (BSG) and non-brain stem glioma (NBSG) cases more
total:6
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 to the paper
R&D Systems anti-human IL-15R antibody was used to perform enzyme-linked immunosorbent assays in order to investigate the relationship between IL-15R and specific immune response. more
total:2
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. 2009 to the paper
R&D Systems anti-human IL-15R antibody was used to perform ELISA in order to investigate the relations between IL-15R and Specific Immune Responses. more
total:16
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. 2011 to the paper
eBioscience anti-IL-17 was used to perform flow cytometry in order to show that blood-brain barrier integrity and CNS immune quiescence was promoted by Sonic hedgehog pathway. more
total:3
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems PE-anti-human IL-17RA was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD. more
total:1
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems APC-anti-human IL-17RC was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD.
total:6
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. 2005 to the paper
BioSource Europe SA anti-IL-18 antibody (which was in ELISA kit) was used in venous blood samples from human and in ELISA to study the association of serum levels of some proinflammatory cytokines in vivo and their correlation with severity of psoriasis. more
total:2
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. 2009 to the paper
R&D Systems anti-IL-18R-PE antibody was used to carry out flow cytometry analysis in order to investigate the mechanism for IL-33 in promoting allergic inflammation. more
total:2
Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma. 2008 to the paper
R&D Systems Cruz anti-IL-19 monoclonal antibody was used to perform western blot in order to study the expression of IL-19 in airway epithelia induced by IL-17A and IL-4/IL-13. more
total:1
Evidence for multiple B- and T-cell epitopes in Plasmodium falciparum liver-stage antigen 3. 2009 to the paper
Unipath mouse anti-IgG4 antibody (1:3000) was used in ELISA to demonstrate that there are several valuable T- and B-cell epitopes in human liver-stage antigen 3 (LSA-3) and to study their roles in inducing protection against Plasmodium falciparum.
total:1
The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. 2009 to the paper
EBioscience antibody against IL-21R was used for flow cytometry in order to demonstrate IL-6 promotes antibody production through increased IL-21 production.
total:3
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems PE-anti-human IL-22 was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD. more
total:1
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. 2011 to the paper
R&D Systems APC-anti-human IL-22RA1 was used to perform flow cytometry in order to show that IL-17 immunodeficiency could lead to CMCD.
total:1
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. 2009 to the paper
R&D Systems anti-IL-22BP was used for neutralization in order to study the function of CD161+ cells that can be activated by IL-23 and mediate destructive tissue inflammation.
total:4
The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells. 2004 to the paper
Invitrogen Therapeutics MDA-7 antibody was used in western blot and immunocytochemistry to study the role of MDA-7/IL-24 in UPR stress pathway and apoptosis. more
total:1
Cardiotrophin-1 stimulation of cardiac fibroblast growth: roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor. 2002 to the paper
Santa Cruz Biotechnology rabbit polyclonal gp130 antibody was used in western blot and immunocytochemistry to study cardiotrophin-1 effect on cardiac fibroblast growth
total:1
IL-32-dependent effects of IL-1beta on endothelial cell functions. 2009 to the paper
R&D Systems anti-human IL-32 was used in western blot in order to study the role for IL-32 in the effect of IL-1 on endothelial cell functions.