APP antibody | antibody review based on formal publications
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| This is a review about APP antibodies, based on 31 published articles using APP antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help Labome/ExactAntigen visitors find the most suited APP antibody. |
Cell Signaling TechnologyCell Signaling Technology APP products | |
| wb | Cell Signaling Technology rabbit anti-APP antibody was used in western blot to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. to the paper |
| ic, wb | Cell Signaling Technology rabbit anti-phospho-APP antibody was used in western blot and immunocytochemistry to detect phospho-APP in CAD cells and mouse cortical neurons, COS-1, MDCK, and bovine aortic endothelial (BAEC) cells. to the paper |
Sigma-AldrichSigma-Aldrich APP products | |
| ih | Sigma mouse anti-human Aβ antibody(clone 4G8) was used in immunohistochemistry to study the role for lactadherin in Alzheimer s disease in sections from human. to the paper |
| wb | Sigma-Aldrich polyclonal anti-APP C-terminal antibody(1/4,000) was used in western blot to detect the early phenotypic modifications of Alzheimer's disease (AD) models. to the paper |
| ip, wb | Sigma anti-APP-CTF antibody (A8717) was used in human cells and in western blot, immunoprecipitation to study the role for ubiquilin 1 in modulating amyloid precursor protein trafficking and Abeta secretion. to the paper |
| ih | Sigma rabbit polyclonal anti-Amyloid Peptide β antibody (A1976) was used in tissue sections from human brain and in immunohistochemistry to study the expression of serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. to the paper |
| wb | Sigma rabbit polyclonal anti-APP antibody (alphaAPP/C) was used in western blot to study the interaction of AICD with FE65 and 14-3-3 modulate FE65-dependent gene transactivation. to the paper |
| wb | Sigma anti-APP C-terminal antibody against the residues 676 695 of APP695 was used in western blot to study intermolecular interactions and function of presenilin complexes. to the paper |
| wb | Sigma anti-APP 6E10 antibody was used in western blot to study the pathway for platelet-derived growth factor to induce the beta-gamma-secretase-mediated cleavage of alzheimer's amyloid precursor protein. to the paper |
| wb | Sigma polyclonal anti-C terminus of APP antibody was used in human embryonic kidney 293 cells and in western blot to study the effect of presenilin 1 mutations on gamma42-secretase and epsilon-secretase cleavage of amyloid precursor protein (APP) and s3-cleavage of notch. to the paper |
InvitrogenInvitrogen APP products | |
| ih | Zymed Lab. anti-?-amyloid Precursor Protein (?-APP) antibody was used in immunohistochemistry to investigate the role of FGF receptor (Fgfr) signaling in Schwann cells and the consequent regulation of normal Schwann cell-axon interactions. to the paper |
| ih | BioSource rabbit pan-Abeta antibody was used in immunohistochemistry to investigate the immunoreactivity of Abeta in mouse brain hemisphere. to the paper |
| ip | BioSource International mouse anti APP monoclonal antibody was used in immunoprecipitation to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. to the paper |
| ip, wb | Zymed APP ZMD.316 polyclonal antibody was used in western blot and immunoprecipitation to investigate the binding of BRI2 to APP precursor protein. to the paper |
| elisa | BioSource International human Abeta 40 colorimetric ELISA kit was used to study amyloid precursor protein cleavage through a JNK-dependent MAPK pathway. to the paper |
| ic | Zymed anti-APP antibody was used in immunocytochemistry to detect APP in CAD cells to further characterize the nature of the speckle-associated pAPP antigen. to the paper |
| wb | Zymed Laboratories anti-Amyloid beta Protein Precursor antibody was used in western blot to detect AbetaPP in HEK 293 cells transfected with various combinations of JIP-1, JNK, and MLK3. to the paper |
| wb | Zymed Laboratories Inc anti-APP CT695 antibody was used in western blot to study the pathway for platelet-derived growth factor to induce the beta-gamma-secretase-mediated cleavage of alzheimer's amyloid precursor protein. to the paper |
MilliporeMillipore APP products | |
| wb | Chemicon monoclonal anti-Aβ(4GB) antibody was used in western blot in oder to study the role of NGF or BDNF signaling in neuronal apoptotic death. to the paper |
| wb | Chemicon mouse monoclonal anti-AβPPs antibody (cat. no. Mab348) was used in western blot to study the expressions of BI-associated biomarkers and the pathogenesis during acute brain injury caused by Toxocara canis in mice. to the paper |
| wb | Chemicon International anti-sAPP beta antibody (APP-WT) and anti-total sAPP antibody (22C11) were used in human cells and in western blot to study the role for ubiquilin 1 in modulating amyloid precursor protein trafficking and Abeta secretion. to the paper |
| ic, ih | CHEMICON International mouse anti Alzheimer precursor protein A4 antibody was used in immunohistochemistry and immunocytochemistry to study the coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. to the paper |
| ip, wb | Chemicon 22C11 APP monoclonal antibody was used in western blot and immunoprecipitation to investigate the binding of the BRI2 to APP precursor protein. to the paper |
| wb | Chemicon monoclonal anti-APP antibody was used in western blot to detect APP in CHO-APP695 Cells. to the paper |
| ip, wb | Chemicon International monoclonal APP NTF (22C11) antibody and polyclonal APP CTF antibody was used in Western blot and immunoprecipitation to study the biological function of presenilin-1 maturation. to the paper |
| wb | Chemicon anti-APP monoclonal antibody was used in western blot to study Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. to the paper |
| wb | Chemicon anti-APP N-terminal antibody against the residues 99 126 of APP695 was used in western blot to study intermolecular interactions and function of presenilin complexes. to the paper |
| ic, wb | Chemicon International rabbit anti-APP antibody was used in western blot and immunocytochemistry to detect APP in CAD cells with APP transfection. to the paper |
| ic | Upstate Biotechnology anti-APP antibody 22C11 was used in immunocytochemistry to study the effect of APP-BP1 on APP-induced apoptosis and DNA synthesis in Alzheimer's disease brain. to the paper |
| wb | Chemicon anti-Amyloid beta Protein Precursor antibody was used in western blot to detect AbetaPP in HEK 293 cells transfected with various combinations of JIP-1, JNK, and MLK3. to the paper |
| wb | Chemicon rabbit polyclonal APP antibody was used in western blot to study the linking of amyloid protein precursor to the kinesin light chain through the scaffold protein JNK-interacting protein 1. to the paper |
| wb | Chemicon anti-APP (Alz-90) antibody was used in Western blot to study the function of presenilin 1 mutations in kinesin-based axonal transport. to the paper |
| wb | Chemicon anti-APP monoclonal antibody 22C11 was used in western blot in the study of the tyrosine-phosphorylation of the beta-amyloid precursor protein APP in cells expressing a constitutively active form of the Abl protoncogene. to the paper |
| BOEHRINGER | |
| ic, ih | Boehringer anti-APP antibody was used in immunohistochemistry and immunocytochemistry to study the distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis. to the paper |
| ELAN PHARMACEUTICALS | |
| ic | Elan Pharmaceuticals monoclonal antibody against Abeta- (1 5) was used in immunocytochemistry to study hypoxic augmentation of Ca2+ channel currents. to the paper |
| ih | Elan Pharmaceuticals Aβ antibody was used in immunohistochemistry to study the association of the cholesterol 24-hydroxylase (CYP46) intron 2 polymorphism with Alzheimer's disease. to the paper |
| SENETEK PLC | |
| ip, wb | Senetek PLC anti-APP 369 monoclonal antibody was used in immunoprecipitation and western blot in the study of the tyrosine-phosphorylation of the beta-amyloid precursor protein APP in cells expressing a constitutively active form of the Abl protoncogene. to the paper |
| SYNETEK | |
| wb | Synetek anti-Abeta antibody 6E10 that recognizes residues 1-16 of Abeta was used in western blot to study BACE2 functions as an alternative alpha-secretase in cells. to the paper |
| SIGNET LABS | |
| ih | Signet Labs A beta peptide (6E10, 1 : 400) antibody was used in immunohistochemistry to study a novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology. to the paper |
| EVOTEC | |
| elisa, ih | Evotec mouse monoclonal Abeta antibody 6H1 (against amino acids 1-17) was used in immunohistochemistry and ELISA to study Abeta 42-induced neprilysin increase. to the paper |
| SENETEK | |
| ih | Senetek anti-amyloid-β peptide(Aβ) antibody(4G8) was used in immunohistochemistry to study whether PGRN genetic variability contributed to other common neurodegenerative brain diseases, such as Alzheimer disease (AD) or Parkinson disease (PD) in sections from human. to the paper |
Articles Reviewed | |
| 1: | Miki Furusho et al. Disruption of fibroblast growth factor receptor signaling in nonmyelinating Schwann cells causes sensory axonal neuropathy and impairment of thermal pain sensitivity. 2009 |
| 2: | Chien-Wei Liao et al. Brain injury-associated biomarkers of TGF-beta1, S100B, GFAP, NF-L, tTG, AbetaPP, and tau were concomitantly enhanced and the UPS was impaired during acute brain injury caused by Toxocara canis in mice. 2008 Reagent reviews based on this publication are available for hydrogen peroxide, avidin/biotin blocking kit, normal goat serum, DAB, Gill's hematoxylin, mounting medium, and protease inhibitor cocktail. |
| 3: | Carmela Matrone et al. NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons. 2008 This publication discusses NTRK1, NGF, brain derived neurotrophic factor, BACE1, TUBB1, and PSEN1. Reagent reviews based on this publication are available for TrK A, NGF, BDNF, BACE, α-tubulin, and PS1. |
| 4: | Cristina Caballero et al. Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice. 2007 |
| 5: | J B Leverenz et al. A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology. 2007 This publication discusses TDP 43, alpha synuclein, APP, and UBB. Reagent reviews based on this publication are available for TDP-43, alpha-synuclein, A beta peptide, and ubiquitin. |
| 6: | Jacques Boddaert et al. Evidence of a role for lactadherin in Alzheimer's disease. 2007 This publication discusses LAMP2, TSG101, HLA-C, and APP. Reagent reviews based on this publication are available for Lamp-2, tsg101, MHC class I, and Aβ. |
| 7: | Nathalie Brouwers et al. Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. 2007 This publication discusses APP, MAPT, UBC, alpha synuclein, and TDP 43. Reagent reviews based on this publication are available for Aβ, tau, ubiquitin, alpha-synuclein, and TAR DNA-binding protein 43. |
| 8: | Tarja Malm et al. beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits. 2006 |
| 9: | Dietrich E Lorke et al. Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. 2006 This publication discusses HTR2A and HTR6. Reagent reviews based on this publication are available for serotonin 2A receptor and serotonin 6 receptor. |
| 10: | Mikko Hiltunen et al. Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion. 2006 This publication discusses UBQLN1, ADAM10, BACE1, APBB2, APP, and transferrin receptor 2. Reagent reviews based on this publication are available for Ubiquilin, ADAM10, BACE1, FE65, APP, Transferrin receptor, UBQLN1, and sAPP. |
| 11: | Kohsuke Kanekura et al. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. 2005 This publication discusses Cu Zn superoxide dismutase, RAC1, CDC42, RHOA, ACTB, APP, PSEN1, PSEN2, and AKT1. Reagent reviews based on this publication are available for SOD1, Rac1, Cdc42, RhoA, actin, APP, PS1, PS2, and phosphorylated-Akt (Ser-473). |
| 12: | Stephen T Brown et al. Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain. 2005 |
| 13: | Shuxia Zhou et al. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production. 2005 This publication discusses nicastrin, APP, and PSEN1. Reagent reviews based on this publication are available for Nct, APP, and Psn-1. |
| 14: | Akio Sumioka et al. Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment. 2005 This publication discusses SYT1. Reagent reviews based on this publication are available for synaptotagmin 1. |
| 15: | Yoshifumi Nakaya et al. Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides. 2005 This publication discusses PSEN1, nicastrin, and USO1. Reagent reviews based on this publication are available for PS1, nicastrin, and p115. |
| 16: | Zoia Muresan et al. Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. 2005 This publication discusses APP, MAPK8IP1, and MAPK8IP2. Reagent reviews based on this publication are available for amyloid-beta protein, Alzheimer precursor protein A4, JIP-1, JIP-2, and APP. |
| 17: | Shuji Matsuda et al. The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production. 2005 This publication discusses ITM2B, APLP1, APLP2, and APP. Reagent reviews based on this publication are available for BRI2, APLP1, APLP2, and APP. |
| 18: | Martin Ingelsson et al. Lack of association of the cholesterol 24-hydroxylase (CYP46) intron 2 polymorphism with Alzheimer's disease. 2004 |
| 19: | Hiroshi Hasegawa et al. Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. 2004 This publication discusses nicastrin and APP. Reagent reviews based on this publication are available for nicastrin and APP. |
| 20: | Zoia Muresan et al. A phosphorylated, carboxy-terminal fragment of beta-amyloid precursor protein localizes to the splicing factor compartment. 2004 This publication discusses SMN1 and APP. Reagent reviews based on this publication are available for SMN and APP. |
| 21: | Yung-Feng Liao et al. Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway. 2004 This publication discusses APP and MAPK8. Reagent reviews based on this publication are available for Abeta 40 and JNK. |
| 22: | Meir H Scheinfeld et al. Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1. 2003 This publication discusses MAP3K11, MAPK8, and APP. Reagent reviews based on this publication are available for MLK3, JNK1, and Amyloid beta Protein Precursor. |
| 23: | Gustavo Pigino et al. Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. 2003 This publication discusses APP, SNAP, STX1A, and GSK3B. Reagent reviews based on this publication are available for APP, SNAP25, syntaxin-1, and GSK3beta. |
| 24: | Davide Gianni et al. Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway. 2003 This publication discusses PDGFB, galectin 4, MAPK1, and APP. Reagent reviews based on this publication are available for PDGF, Gal4DBD, phosphoERK, and APP. |
| 25: | Shuji Matsuda et al. Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. 2003 This publication discusses APLP2. Reagent reviews based on this publication are available for alpha APLP2. |
| 26: | Yuzhi Chen et al. APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain. 2003 This publication discusses NEDD8. Reagent reviews based on this publication are available for BrdU and NEDD8. |
| 27: | M Hasan Mohajeri et al. Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo. 2002 This publication discusses APP and MME. Reagent reviews based on this publication are available for Abeta 1-17 and NEP. |
| 28: | Fusheng Chen et al. Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch. 2002 |
| 29: | R Yan et al. BACE2 functions as an alternative alpha-secretase in cells. 2001 This publication discusses APP, STX6, KIR2DL3, COPB1, and BACE1. Reagent reviews based on this publication are available for Abeta, APP, syntaxin 6, p58, beta-COP, and BACE1. |
| 30: | B Kornek et al. Distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis. 2001 This publication discusses myelin oligodendrocyte glycoprotein, PLP1, 2 3 cyclic nucleotide 3 phosphodiesterase, MBP, APP, and ADRA1B. Reagent reviews based on this publication are available for MOG, proteolipid protein, 2',3'-cyclic nucleotide phospho- diesterase, myelin basic protein, beta-amyloid precursor protein, and alpha1B. |
| 31: | N Zambrano et al. The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. 2001 This publication discusses APBB1 and APP. Reagent reviews based on this publication are available for Fe65 and APP. |