product summary
request information :
company name :
US Biological
product type :
antibody
product name :
Survivin, NT (TIAP, API4)
catalog :
S8500-05
quantity :
100 ug
price :
395.64 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
more info or order :
product information
Catalog Number :
S8500-05
Product wo Prefix :
Survivin, NT (TIAP, API4)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
100 ug
Size1 List :
395.64 USD
Isotype :
IgG
Desc1 :
Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1). Applications: This polyclonal antibody can be used for detection of survivin by Western blot. MOLT4 cell lysate can be used as positive control and an approximate 16kDa band should be detected. Other applications have not been tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Calc Crossreactivity :
Hu
Immunogen :
Peptide corresponding to amino acids 1 to 12 of human origin (1).
Specificity :
Recognizes human Survivin (NT) TIAP/API4
Purity :
Purified by Immunoaffinity chromatography
Form :
Supplied as a liquid in PBS, 0.02% sodium azide.
Concentration :
0.5mg/ml
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: 0.5mg/ml Form: Supplied as a liquid in PBS, 0.02% sodium azide. Purity: Purified by Immunoaffinity chromatography. Immunogen: Peptide corresponding to amino acids 1 to 12 of human origin (1). Specificity: Recognizes human Survivin (NT) TIAP/API4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
WB
Storage Temperature :
4°C (-20°C Glycerol)
Reference :
1. Ambrosini, G., Adida, C., Altieri, D.C., Nat. Med. 3: 917-921, 1997. 2. Li, F., et al., Nature 396: 580-584, 1998. 3. Kobayashi, K., et al., Proc. Natl. Acad. Sci. USA 96: 1,457- 1,462, 1999
more info or order :
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
www.usbio.net
800-520-3011
headquarters: USA
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