DUSP10 Polyclonal Antibody | Invitrogen PA5-15559 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DUSP10 Polyclonal Antibody

catalog :

PA5-15559

quantity :

400µL

price :

US 330.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

DUSP10 Polyclonal Antibody

Catalog # :

PA5-15559

Quantity :

400µL

Price :

US 330.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. The protein is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli.

Immunogen :

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP10

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000

Aliases :

Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5;