Phospho-AKT pThr308 Polyclonal Antibody | Invitrogen PA1-540 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon

product type :

antibody

product name :

Phospho-AKT pThr308 Polyclonal Antibody

catalog :

PA1-540

quantity :

200 µg

price :

US 324

clonality :

polyclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, fruit fly

application :

western blot

product information

Product Type :

PA1-540

Product Name :

Phospho-AKT pThr308 Polyclonal Antibody

Catalog # :

PA1-540

Quantity :

200 µg

Price :

US 324

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Drosophila, Human, Mouse, Rat

Applications :

Western Blot

Species :

Dm, Hu, Ms, Rt

Gene Identification :

Entrez: 41957, 207, 11651, 24185; Uniprot: Q8INB9, P31749, P31750, P47196

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Protein kinase B (PKB), also known as Akt, is an oncogenic serine-threonine kinase originally cloned from the retrovirus AKT8. PKB is a direct target of phosphatidylinositol 3-kinase (PI3-kinase) and is activated in response to a variety of growth factors including insulin and platelet-derived growth factor (PDGF). PKB also plays an important role in many PI3-kinase dependent cellular functions including inhibition of apoptosis. Activity of PKB has been associated with the phosphorylation of two sites: T308, in the activation loop of the kinase, and S473, at the carboxyl terminus. Phosphorylation of both sites contributes to PKB activity, however phosphorylation of T308 has been shown to be absolutely essential for PKB activation.

Immunogen :

Synthetic phosphopeptide corresponding to residues D(302) G A T M K T(p) F C G T P E(314) of mouse PKB.

Format :

Liquid; PBS with 1 mg/ml BSA, 0.05 % sodium azide

Applications w/Dilutions :

WB 10 µg/ml

Aliases :

PKB, AKT

PubMed References :

8978681