H-Ras Polyclonal Antibody | Invitrogen PA1-27524 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

H-Ras Polyclonal Antibody

catalog :

PA1-27524

quantity :

50µg

price :

US 425.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

H-Ras Polyclonal Antibody

Catalog # :

PA1-27524

Quantity :

50µg

Price :

US 425.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Chicken

Reactivity :

Mouse, Rat

Applications :

Western Blot: Assay Dependent

Species :

Mouse, Rat

Isotype :

IgY

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Immunogen :

Synthetic peptide corresponding to human GTPase HRas.

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay Dependent

Aliases :

Ha-Ras, Harvey-ras, Hras, H-Ras-1, Transforming protein p21, c-H-ras, p21ras, Ras, GTPase Hras, Hras1