SMAD4 Monoclonal Antibody (SMD46 (DCS-46)), Biotin | Invitrogen MA5-14297 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SMAD4 Monoclonal Antibody (SMD46 (DCS-46)), Biotin

catalog :

MA5-14297

quantity :

500µL

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

SMD46 (DCS-46)

reactivity :

human, common platanna

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human western blot; human	Xiao D, Wen J, Li J, Wang K, Hu Z, Zhou J, et al. Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cells. Acta Biochim Biophys Sin (Shanghai). 2006;38:883-92 pubmed
immunoprecipitation; common platanna western blot; common platanna	Abe T, Furue M, Kondow A, Matsuzaki K, Asashima M. Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A. Mech Dev. 2005;122:671-80 pubmed

product information

Product Type :

Antibody

Product Name :

SMAD4 Monoclonal Antibody (SMD46 (DCS-46)), Biotin

Catalog # :

MA5-14297

Quantity :

500µL

Price :

US 399.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunofluorescence: Assay Dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Species :

Human

Clone :

SMD46 (DCS-46)

Isotype :

IgG1

Storage :

4° C

Description :

DPC4 (also named SMAD4; small mothers against decapentaplegic deleted in pancreatic carcinoma). The family of SMAD molecules comprises essential mediators of transforming growth factor beta (TGF-beta) signaling. To date, seven members of this family have been identified, each of which plays a specific and separate role in mediating TGF-beta superfamily gene transcription. At least two different members, Smad2 and Smad4/DPC4, have been implicated in human cancer and appear to have tumor-suppressor functions whose inactivation may play an important role in the histogenesis of pancreatic and colorectal malignancy and possibly other human cancers as well.

Immunogen :

Purified recombinant DPC4 protein

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: Assay Dependent, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

MAD homolog 4, MAD, mothers against decapentaplegic homolog 4,SMAD 4, SMAD, mothers against DPP homolog 4, deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, hSMAD4, mothers against DPP homolog 4, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4