product summary
request information :
company name :
Thermo Scientific Pierce Products
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, HyClone, ABgene, Open Biosystems, Dharmacon Research, Affinity BioReagents, Nunc
product type :
antibody
product name :
Estrogen Receptor
catalog :
MA1-12600
quantity :
100 µg
price :
246.00 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry
publications citing this reagent :
- WB(1:100) : human (WB(1:100)) Adami H, Andersson S, Johansson J, Setlur S, Mertz K, Hoshida Y, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst. 2008;100:815-25 PMID 18505969
- WB : mouse (WB) Min C, Kirsch K, Zhao Y, Jeay S, Palamakumbura A, Trackman P, et al. The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res. 2007;67:1105-12 PMID 17283144
- IHC(1:100) : mouse (IHC(1:100)) Mehra R, Sharma K, Nyakas C, Vij U. Estrogen receptor alpha and beta immunoreactive neurons in normal adult and aged female rat hippocampus: a qualitative and quantitative study. Brain Res. 2005;1056:22-35 PMID 16122717
- WB : human (WB) Bourguignon L, Gilad E, Rothman K, Peyrollier K. Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression. J Biol Chem. 2005;280:11961-72 PMID 15655247
- WB : human (WB) Sidell N, Liu J, Hendry L, Tanmahasamut P. Conjugated linoleic acid blocks estrogen signaling in human breast cancer cells. J Nutr. 2004;134:674-80 PMID 14988466
- IHC : human (IHC) Huang A, Leygue E, Snell L, Murphy L, Watson P. Expression of estrogen receptor variant messenger RNAs and determination of estrogen receptor status in human breast cancer. Am J Pathol. 1997;150:1827-33 PMID 9137105
more info or order :
product information
Catalog Number :
MA1-12600
product name :
Estrogen Receptor
Long Product Name :
Estrogen Receptor Antibody (AER311)
product type :
antibody
List Price :
246.00 USD
clonality :
monoclonal
Host Name :
mouse
Clone :
AER311
Isotype :
IgG2a
Product Description :
MA1-12600 detects Estrogen Receptor in human and mouse samples. MA1-12600 has been successfully used in ELISA, immunohistochemistry, western blot and immunoprecipitation procedures. The MA1-12600 immunogen is estrogen receptors from calf uterus.
CrossReactivity :
Hu, Ms
SpeciesSummary :
Human, Mouse
Background :
The Estrogen Receptor (ER) is a 67 kDa protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
ALTnames :
ER
Immunogen :
Estrogen receptors from calf uterus.
buffer :
100 µg of purified antibody (1 mg/ml) in PBS with 0.08% sodium azide.
Preservative :
0.08% Sodium azide
Packaging :
100 µg
PackageSize :
100
Concentration :
1 mg/ml
Uses :
IP (Assay Dependent), WB (Assay Dependent), IHC (Assay Dependent), ELISA (Assay Dependent)
Application Summary :
ELISA, IHC, IP, WB
Storage :
-20° C, Avoid Freeze/Thaw Cycles
more info or order :
company information
Thermo Scientific Pierce Products
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