product summary
request information :
company name :
Thermo Scientific Pierce Products
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Arcturus, Perseptive Biosystems
product type :
product name :
Estrogen Receptor Monoclonal Antibody (AER311)
catalog :
quantity :
100 µg
price :
US 255
clonality :
host :
reactivity :
human, mouse
application :
publications citing this reagent :
total: 11
  1. IHC(1:200)
    Rantala M, Mutikainen M, Schuler G, Katila T, Taponen J. Endometrial expression of progesterone, estrogen, and oxytocin receptors and of 20α-hydroxysteroid dehydrogenase and cyclooxygenase II 2 and 5 days after ovulation in induced short and normal estrous cycles in dairy cows. Theriogenology. 2014;81:1181-8 pubmed publisher
  2. WB(1:100)
    Choudhuri R, DeGraff W, Gamson J, Mitchell J, Cook J. Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines. Front Oncol. 2011;1:19 pubmed
  3. IC
    Larson J, Goodman L, Tan Y, Defazio-Eli L, Paquet A, Cook J, et al. Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens. Patholog Res Int. 2010;2010:814176 pubmed
  4. IHC
    Peng X, Li T, Xia E, Xia C, Liu Y, Yu D. A comparison of oestrogen receptor and progesterone receptor expression in endometrial polyps and endometrium of premenopausal women. J Obstet Gynaecol. 2009;29:340-6 pubmed
  5. IHC
    Abd-Elnaeim M, Derar I, Wilsher S, Allen W, Leiser R, Schuler G. Immunohistochemical localization of oestrogen receptors alpha and beta, progesterone receptor and aromatase in the equine placenta. Reprod Domest Anim. 2009;44:312-9 pubmed publisher
  6. : human (WB(1:100))
    Setlur S, Mertz K, Hoshida Y, Demichelis F, Lupien M, Perner S, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst. 2008;100:815-25 pubmed publisher
  7. WB
    Tekmal R, Nair H, Perla R, Kirma N. HER-2/neu x aromatase double transgenic mice model: the effects of aromatase overexpression on mammary tumorigenesis. J Steroid Biochem Mol Biol. 2007;106:111-8 pubmed
  8. : mouse (WB)
    Min C, Kirsch K, Zhao Y, Jeay S, Palamakumbura A, Trackman P, et al. The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res. 2007;67:1105-12 pubmed
  9. WB
    York B, Lou D, Noonan D. Tuberin nuclear localization can be regulated by phosphorylation of its carboxyl terminus. Mol Cancer Res. 2006;4:885-97 pubmed
  10. : mouse (IHC(1:100))
    Mehra R, Sharma K, Nyakas C, Vij U. Estrogen receptor alpha and beta immunoreactive neurons in normal adult and aged female rat hippocampus: a qualitative and quantitative study. Brain Res. 2005;1056:22-35 pubmed
product information
Product Type :
Product Name :
Estrogen Receptor Monoclonal Antibody (AER311)
Catalog # :
Quantity :
100 µg
Price :
US 255
Clonality :
Purity :
Protein A/G
Host :
Reactivity :
Human, Mouse
Applications :
ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot
Species :
Hu, Ms
Clone :
Gene Identification :
Entrez: 2099, 13982; Uniprot: P03372, P19785
Isotype :
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The Estrogen Receptor (ER) is a 67 kDa protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
Immunogen :
Estrogen receptors from calf uterus.
Format :
Liquid; PBS with 0.08 % sodium azide
Applications w/Dilutions :
IP Assay Dependent, WB Assay Dependent, IHC Assay Dependent, ELISA Assay Dependent
Aliases :
PubMed References :
19835506, 18992099, 22649756, 9137105, 14988466, 15655247, 16122717, 17283144, 18505969, 10480241, 11906916
publications citing this reagent :
  1. : human (WB)
    Bourguignon L, Gilad E, Rothman K, Peyrollier K. Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression. J Biol Chem. 2005;280:11961-72 pubmed
company information
Thermo Scientific Pierce Products
PO Box 117
Rockford, IL 61105
headquarters: USA