product summary
request information :
company name :
Thermo Scientific Pierce Products
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, ABgene, Affinity BioReagents, Nunc
product type :
antibody
product name :
Estrogen Receptor Monoclonal Antibody (AER311)
catalog :
MA1-12600
quantity :
100 µg
price :
US 255
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry
publications citing this reagent :
total: 14
  1. WB(1:100)
    Choudhuri R, DeGraff W, Gamson J, Mitchell J, Cook J. Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines. Front Oncol. 2011;1:19 pubmed
  2. IC
    Larson J, Goodman L, Tan Y, Defazio-Eli L, Paquet A, Cook J, et al. Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens. Patholog Res Int. 2010;2010:814176 pubmed
  3. IHC
    Peng X, Li T, Xia E, Xia C, Liu Y, Yu D. A comparison of oestrogen receptor and progesterone receptor expression in endometrial polyps and endometrium of premenopausal women. J Obstet Gynaecol. 2009;29:340-6 pubmed
  4. IHC
    Abd-Elnaeim M, Derar I, Wilsher S, Allen W, Leiser R, Schuler G. Immunohistochemical localization of oestrogen receptors alpha and beta, progesterone receptor and aromatase in the equine placenta. Reprod Domest Anim. 2009;44:312-9 pubmed publisher
  5. WB(1:100) : human (WB(1:100))
    Setlur S, Mertz K, Hoshida Y, Demichelis F, Lupien M, Perner S, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst. 2008;100:815-25 pubmed publisher
  6. WB
    Tekmal R, Nair H, Perla R, Kirma N. HER-2/neu x aromatase double transgenic mice model: the effects of aromatase overexpression on mammary tumorigenesis. J Steroid Biochem Mol Biol. 2007;106:111-8 pubmed
  7. WB : mouse (WB)
    Min C, Kirsch K, Zhao Y, Jeay S, Palamakumbura A, Trackman P, et al. The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res. 2007;67:1105-12 pubmed
  8. WB
    York B, Lou D, Noonan D. Tuberin nuclear localization can be regulated by phosphorylation of its carboxyl terminus. Mol Cancer Res. 2006;4:885-97 pubmed
  9. IHC(1:100) : mouse (IHC(1:100))
    Mehra R, Sharma K, Nyakas C, Vij U. Estrogen receptor alpha and beta immunoreactive neurons in normal adult and aged female rat hippocampus: a qualitative and quantitative study. Brain Res. 2005;1056:22-35 pubmed
  10. WB : human (WB)
    Bourguignon L, Gilad E, Rothman K, Peyrollier K. Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression. J Biol Chem. 2005;280:11961-72 pubmed
product information
Product Type :
MA1-12600
Product Name :
Estrogen Receptor Monoclonal Antibody (AER311)
Catalog # :
MA1-12600
Quantity :
100 µg
Price :
US 255
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot
Species :
Hu, Ms
Clone :
AER311
Gene Identification :
Entrez: 13982, 2099; Uniprot: P19785, P03372
Isotype :
IgG2a
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The Estrogen Receptor (ER) is a 67 kDa protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
Immunogen :
Estrogen receptors from calf uterus.
Format :
Liquid; PBS with 0.08 % sodium azide
Applications w/Dilutions :
IP Assay Dependent, WB Assay Dependent, IHC Assay Dependent, ELISA Assay Dependent
Aliases :
ER
PubMed References :
9137105, 14988466, 15655247, 16122717, 17283144, 18505969
publications citing this reagent :
  1. WB : human (WB)
    Tanmahasamut P, Liu J, Hendry L, Sidell N. Conjugated linoleic acid blocks estrogen signaling in human breast cancer cells. J Nutr. 2004;134:674-80 pubmed
  2. IHC
    Schuler G, Wirth C, Teichmann U, Failing K, Leiser R, Thole H, et al. Occurrence of estrogen receptor alpha in bovine placentomes throughout mid and late gestation and at parturition. Biol Reprod. 2002;66:976-82 pubmed
  3. EMSA
    Feng W, Graumann K, Hahn R, Jungbauer A. Affinity chromatography of human estrogen receptor-alpha expressed in Saccharomyces cerevisiae. Combination of heparin- and 17beta-estradiol-affinity chromatography. J Chromatogr A. 1999;852:161-73 pubmed
  4. IHC : human (IHC)
    Huang A, Leygue E, Snell L, Murphy L, Watson P. Expression of estrogen receptor variant messenger RNAs and determination of estrogen receptor status in human breast cancer. Am J Pathol. 1997;150:1827-33 pubmed
company information
Thermo Scientific Pierce Products
PO Box 117
Rockford, IL 61105
www.pierce-antibodies.com
8008743723
headquarters: USA