14-3-3 theta Monoclonal Antibody (3B9) | Invitrogen MA1-12431 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

14-3-3 theta Monoclonal Antibody (3B9)

catalog :

MA1-12431

quantity :

100µg

price :

330 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B9

reactivity :

human, mouse, rat, cow

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

14-3-3 theta Monoclonal Antibody (3B9)

Catalog # :

MA1-12431

Quantity :

100µg

Price :

330 USD

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

ELISA: Assay Dependent, Western Blot: 1:5000

Species :

Bovine, Human, Mouse, Rat

Clone :

3B9

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells. Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing. The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and, through interaction with Bad, prevents apoptosis. Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen, nitrate reductase, S-raf and the IGF-1 receptor. Detection of 14-3-3 proteins in cerebrospinal fluid has been shown to be quite useful in the differential diagnosis of Creutzfeldt-Jakob disease and other prion diseases.

Immunogen :

Recombinant 14-3-3-theta/tau protien.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Western Blot: 1:5000

Aliases :

14-3-3, 1C5, HS1