product summary
request information :
company name :
Thermo Scientific Pierce Products
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Arcturus, Perseptive Biosystems
product type :
product name :
Integrin beta-3 / CD61 Monoclonal Antibody, FITC conjugate (43.PL)
catalog :
quantity :
100 Tests
price :
US 292
clonality :
host :
reactivity :
application :
flow cytometry
product information
Product Type :
Product Name :
Integrin beta-3 / CD61 Monoclonal Antibody, FITC conjugate (43.PL)
Catalog # :
Quantity :
100 Tests
Price :
US 292
Clonality :
Purity :
Protein A/G
Host :
Reactivity :
Applications :
Flow Cytometry
Species :
Clone :
Gene Identification :
Entrez: 3690; Uniprot: P05106
Isotype :
Storage :
4° C, do not freeze
Description :
CD61 recognizes an Mr 110-kdalton (kDa) protein, also known as gpIIIa, the common ßsubunit (integrin ß3-chain) of the gpIIb/IIIa complex and the vitronectin receptor (VNR). The gpIIb/IIIa complex and the VNR are integrins, ie, a/b-heterodimeric glycoprotein complexes that are involved in cell adhesion. With the CD41 antigen (gpIIb or aIIb), the CD61 antigen forms the gpIIb/IIIa complex, which acts as a receptor for fibrinogen, von Willebrand factor (vWf), fibronectin and vitronectin on activated platelets. With the CD51 antigen (VNR a-chain or av), the CD61 antigen forms the VNR, which mediates activation-independent cell adhesion to vitronectin, vWf, fibrinogen, and thrombospondin. The CD61 antigen is found on all normal resting and activated platelets. The CD61 antigen is also found on endothelial cells, megakaryocytes, on some myeloid, erythroid and T-lymphoid leukemic cell lines.
Immunogen :
purified platelet membrane glycoproteins
Format :
Liquid; PBS with 0.2 % carrier protein, 0.08 % sodium azide
Applications w/Dilutions :
FACS Assay Dependent
Aliases :
BDPLT2, CD61, GP3A, GPIIIa, GT, integrin beta-3, platelet glycoprotein IIIa, platelet membrane glycoprotein IIIa, ITGB3
company information
Thermo Scientific Pierce Products
PO Box 117
Rockford, IL 61105
headquarters: USA