product summary
request information :
company name :
Thermo Scientific Pierce Products
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, HyClone, ABgene, Open Biosystems, Dharmacon Research, Affinity BioReagents, Nunc
product type :
antibody
product name :
Integrin beta-3
catalog :
MA1-12148
quantity :
100 Tests
price :
281.00 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
FACS
more info or order :
product information
Catalog Number :
MA1-12148
product name :
Integrin beta-3
Long Product Name :
Integrin beta-3 Antibody, FITC conjugate (43.PL)
product type :
antibody
List Price :
281.00 USD
clonality :
monoclonal
Host Name :
mouse
Clone :
43.PL
conjugate :
FITC
Isotype :
IgG1
Product Description :
MA1-12148 detects CD61 in human samples. MA1-12148 has been successfully used in FACS procedures. The MA1-12148 immunogen is white blood cells.
CrossReactivity :
Hu
SpeciesSummary :
human
Background :
CD61 recognizes an Mr 110-kdalton (kDa) protein, also known as gpIIIa, the common ßsubunit (integrin ß3-chain) of the gpIIb/IIIa complex and the vitronectin receptor (VNR). The gpIIb/IIIa complex and the VNR are integrins, ie, a/b-heterodimeric glycoprotein complexes that are involved in cell adhesion. With the CD41 antigen (gpIIb or aIIb), the CD61 antigen forms the gpIIb/IIIa complex, which acts as a receptor for fibrinogen, von Willebrand factor (vWf), fibronectin and vitronectin on activated platelets. With the CD51 antigen (VNR a-chain or av), the CD61 antigen forms the VNR, which mediates activation-independent cell adhesion to vitronectin, vWf, fibrinogen, and thrombospondin. The CD61 antigen is found on all normal resting and activated platelets. The CD61 antigen is also found on endothelial cells, megakaryocytes, on some myeloid, erythroid and T-lymphoid leukemic cell lines.
ALTnames :
Integrin beta-3, GP3A, HPA 1, HPA 4, ITGB3, NAIT , Platelet fibrinogen receptor beta subunit, platelet glycoprotein IIIa precursor, PTP
Immunogen :
White blood cells.
buffer :
100 tests in PBS with 0.08% sodium azide and 0.2% carrier protein.
Preservative :
0.08% Sodium azide
Packaging :
100 Tests
PackageSize :
100
Uses :
FACS (Assay Dependent)
Application Summary :
FACS
Storage :
4° C, do not freeze
more info or order :
company information
Thermo Scientific Pierce Products