TCR beta Monoclonal Antibody (H57-597) | Invitrogen MA1-10456 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCR beta Monoclonal Antibody (H57-597)

catalog :

MA1-10456

quantity :

100 ug

price :

US 99

clonality :

monoclonal

host :

hamsters

clone name :

H57-597

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

citations: 17

Published Application/Species/Dilution	Reference
immunocytochemistry; mouse; fig 1	Lin W, Fan Z, Suo Y, Deng Y, Zhang M, Wang J, et al. The bullseye synapse formed between CD4+ T-cell and staphylococcal enterotoxin B-pulsed dendritic cell is a suppressive synapse in T-cell response. Immunol Cell Biol. 2015;93:99-110 pubmed publisher
flow cytometry; mouse	Ohteki T, MacDonald H. Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice. J Exp Med. 1994;180:699-704 pubmed
flow cytometry; mouse	Ohteki T, Iwamoto M, Izui S, MacDonald H. Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur J Immunol. 1995;25:37-41 pubmed
flow cytometry; mouse	Kretz-Rommel A, Rubin R. Persistence of autoreactive T cell drive is required to elicit anti-chromatin antibodies in a murine model of drug-induced lupus. J Immunol. 1999;162:813-20 pubmed
flow cytometry; mouse	Walker C, Hautefort I, Dalton J, Overweg K, Egan C, Bongaerts R, et al. Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge. PLoS ONE. 2013;8:e84553 pubmed publisher
flow cytometry; mouse	Pear W, Aster J, Scott M, Hasserjian R, Soffer B, Sklar J, et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med. 1996;183:2283-91 pubmed
flow cytometry; mouse; fig 5	Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard G. Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin. Cell Tissue Res. 2008;334:227-42 pubmed publisher
flow cytometry; mouse; fig 3	Flano E, Kim I, Moore J, Woodland D, Blackman M. Differential gamma-herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice. J Immunol. 2003;170:3828-34 pubmed
other; mouse	Koneru M, Schaer D, Monu N, Ayala A, Frey A. Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function. J Immunol. 2005;174:1830-40 pubmed
flow cytometry; mouse	Fucs R, Jesus J, Souza Junior P, Franco L, Verícimo M, Bellio M, et al. Frequency of natural regulatory CD4+CD25+ T lymphocytes determines the outcome of tolerance across fully mismatched MHC barrier through linked recognition of self and allogeneic stimuli. J Immunol. 2006;176:2324-9 pubmed
flow cytometry; mouse	Ikawa T, Kawamoto H, Fujimoto S, Katsura Y. Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med. 1999;190:1617-26 pubmed
flow cytometry; mouse; tbl 2	Mandal M, Donnelly R, Elkabes S, Zhang P, Davini D, David B, et al. Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring. Brain Behav Immun. 2013;33:33-45 pubmed publisher
flow cytometry; mouse	Reading P, Smith G. A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J Gen Virol. 2003;84:1973-83 pubmed
flow cytometry; mouse	Zhang T, He X, Tsang T, Harris D. Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function. Cancer Gene Ther. 2004;11:487-96 pubmed
flow cytometry; mouse; fig 1	Germeraad W, Kawamoto H, Itoi M, Jiang Y, Amagai T, Katsura Y, et al. Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors. J Histochem Cytochem. 2003;51:1225-35 pubmed
flow cytometry; mouse	Petrie H, Livak F, Burtrum D, Mazel S. T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production. J Exp Med. 1995;182:121-7 pubmed
flow cytometry; mouse; fig 1	Radoja S, Saio M, Frey A. CD8+ tumor-infiltrating lymphocytes are primed for Fas-mediated activation-induced cell death but are not apoptotic in situ. J Immunol. 2001;166:6074-83 pubmed

product information

Product Type :

MA1-10456

Product Name :

TCR beta Monoclonal Antibody (H57-597)

Catalog # :

MA1-10456

Quantity :

100 ug

Price :

US 99

Clonality :

Monoclonal

Purity :

protein A

Host :

Armenian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) and Immunoprecipitation

Species :

Clone :

H57-597

Gene Identification :

Entrez: 21577

Isotype :

IgG

Storage :

4° C, do not freeze

Description :

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the beta locus are known to be incapable of encoding a protein and are considered pseudogenes. The beta locus also includes several trypsinogen genes. [provided by RefSeq, Jul 2008]

Immunogen :

Affinity purified TCR from DO-11.10 T cell hybridoma

Format :

Liquid; PBS with 15 mM sodium azide

Applications w/Dilutions :

FACS 1-2 ug/ml, IP 1-2 ug/ml, FN Assay Dependent, IHC (P) Assay-Dependent, IHC (F) Assay-Dependent, ICC Assay-Dependent

Aliases :

TCRbeta, Tib