product summary
request information :
company name :
Spring Bioscience Corp.
product type :
antibody
product name :
Anti AKT-1/AKT-2 Antibody
catalog :
E10840
quantity :
0.1 ml
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human, rat, mouse
application :
western blot, immunohistochemistry
image
image 1 :
Spring Bioscience Corp. E10840 image 1
product information
# :
49
Spring Catalog Number :
E10840
Spring Root Cat# :
E1084
Antibody Target :
AKT-1/AKT-2
Antibody Name :
Anti AKT-1/AKT-2 Antibody
Product Description :
Two serine/threonine kinases, designated AKT-1 and AKT-2 (alternatively referred to as PKB or RacPK), exhibit sequence homology with the protein kinase A and C families and are encoded by the c-akt proto-oncogene. AKT-1 and AKT-2 contain a Pleckstrin homology (PH) domain and are activated by PDGF stimulation. This activation is dependent on PDGFR-beta tyrosine residues 740 and 751, which bind the 85kDa subunit of the phosphatidylinositol 3-kinase (PI-3 kinase) complex. The protein may signal downstream of the PI kinases.
Quantity/Pack Size :
0.1 ml
IHC Dilution :
1:50
Host Species :
Rabbit
Validated Applications :
Immunohistochemistry
Species Reactivity :
Human
Pathway :
AKT/PKB Signaling
Regulatory Status :
Research Use Only (RUO)
Antibody Type :
Polyclonal
Conjugate :
Unconjugated
IHC Image File Name :
E1084 W (Akt 1 2) Lung Carcinoma.jpg
Primary or Secondary Antibody :
Primary Antibody
Immunigen :
Synthetic peptide from N-terminus of human AKT-1.
Isotype :
Rabbit IgG
Form/Presentation :
Concentrate
company information
Spring Bioscience Corp.
6920 Koll Center Pkwy, Ste. 211
Pleasanton, CA 94566
info@springbio.com
www.springbio.com
800 787-6896
headquarters: USA

Founded in 2001, Spring Bioscience was acquired by Ventana Medical Systems who is now a part of the Roche Group. Through our role as a leading antibody development center for Roche, Spring Bioscience is well-positioned to deliver a focused product portfolio to the research market representing the highest value targets for the future diagnosis and prognosis of cancer.

Spring’s products are optimized to help you deliver consistent and high quality results in your laboratory. Our in house rabbit monoclonal technology improves upon traditional hybridoma approaches, allowing us to accelerate the delivery of a broader menu of highly specific and sensitive monoclonal antibodies (SP clones) to the research market. Having developed the SP1 clone, the current gold standard Estrogen Receptor (ER) marker, SP clones continue to emerge as best-in-class cancer markers for your immunohistochemistry (IHC) research.

Spring’s antibody technologies include rabbit monoclonal (SP clones), mouse monoclonal (SPM clones) and rabbit polyclonal. We offer these in four configurations, validated in multiple species, and often optimized for not just IHC but other applications including Western Blot. In addition to our line of antibodies we also sell a complete line of complementary IHC reagents and detection systems as well as an Antibody Microarray to assist in early stage research studies.