product summary
request information :
company name :
Santa Cruz Biotechnology
product type :
product name :
ERalpha (MC-20) Antibody
catalog :
quantity :
200 µg/ml
price :
279 USD
clonality :
host :
reactivity :
human, mouse, rat, pig
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 229
  • western blot (knockout validation); mouse; 1:200; fig s3
Yuchi Y, Cai Y, Legein B, De Groef S, Leuckx G, Coppens V, et al. Estrogen Receptor α Regulates β-Cell Formation During Pancreas Development and Following Injury. Diabetes. 2015;64:3218-28 pubmed publisher
  • immunohistochemistry (knockout validation); mouse; fig 3c
Hsu I, Yeh C, Slavin S, Miyamoto H, Netto G, Tsai Y, et al. Estrogen receptor alpha prevents bladder cancer via INPP4B inhibited akt pathway in vitro and in vivo. Oncotarget. 2014;5:7917-35 pubmed
  • western blot; mouse; 1:1000
Koren S, Reavie L, Couto J, De Silva D, Stadler M, Roloff T, et al. PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours. Nature. 2015;525:114-8 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1 ug/ml; fig 1
Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed publisher
  • immunohistochemistry; mouse; 1:750
Dabydeen S, Kang K, Diaz-Cruz E, Alamri A, Axelrod M, Bouker K, et al. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 2015;36:122-32 pubmed publisher
  • immunohistochemistry - frozen section; pig; 1:1000
Jana B, Całka J, Rytel L, Czarzasta J. Morphological and neurochemical characterization of the ovarian sympathetic chain ganglia perikarya in testosterone-treated sexually matured pigs. Ann Anat. 2015;202:28-35 pubmed publisher
  • immunohistochemistry - frozen section; rat
Stamatakis A, Kalpachidou T, Raftogianni A, Zografou E, Tzanou A, Pondiki S, et al. Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain. Psychoneuroendocrinology. 2015;52:212-28 pubmed publisher
  • western blot; mouse
Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells. 2015;33:742-50 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • chromatin immunoprecipitation; human
Guertin M, Zhang X, Anguish L, Kim S, Varticovski L, Lis J, et al. Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure. PLoS Genet. 2014;10:e1004613 pubmed publisher
  • western blot; mouse
Rohringer S, Holnthoner W, Hackl M, Weihs A, Rünzler D, Skalicky S, et al. Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells. PLoS ONE. 2014;9:e114806 pubmed publisher
  • western blot; rat; 1:500
Sase S, Meyer K, Lubec G, Korz V. Different expression of membrane-bound and cytosolic hippocampal steroid receptor complexes during spatial training in young male rats. Eur Neuropsychopharmacol. 2014;24:1819-27 pubmed publisher
  • immunocytochemistry; human; 1:250
Burns K, Li Y, Liu L, Korach K. Research resource: comparison of gene profiles from wild-type ERα and ERα hinge region mutants. Mol Endocrinol. 2014;28:1352-61 pubmed publisher
  • immunohistochemistry - paraffin section; human
Sato M, Kadota M, Tang B, Yang H, Yang Y, Shan M, et al. An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-beta in human breast cancer. Breast Cancer Res. 2014;16:R57 pubmed
  • chromatin immunoprecipitation; human
Coomans de Brachène A, Bollaert E, Eijkelenboom A, de Rocca Serra A, van der Vos K, Burgering B, et al. The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway. Biochem J. 2014;460:25-34 pubmed publisher
  • western blot; mouse; 1:200
Spruiell K, Jones D, Cullen J, Awumey E, Gonzalez F, Gyamfi M. Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice. Biochem Pharmacol. 2014;89:399-412 pubmed publisher
  • immunohistochemistry; mouse; fig 7
Cicchini M, Chakrabarti R, Kongara S, Price S, Nahar R, Lozy F, et al. Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. Autophagy. 2014;10:2036-52 pubmed publisher
  • immunohistochemistry; mouse; 1:750
Assefnia S, Kang K, Groeneveld S, Yamaji D, Dabydeen S, Alamri A, et al. Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer. Endocr Relat Cancer. 2014;21:443-57 pubmed publisher
  • western blot; mouse
Marttinen M, Pajari A, Paivarinta E, Storvik M, Marttinen P, Nurmi T, et al. Plant sterol feeding induces tumor formation and alters sterol metabolism in the intestine of Apc(Min) mice. Nutr Cancer. 2014;66:259-69 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Sizemore G, Sizemore S, Pal B, Booth C, Seachrist D, Abdul-Karim F, et al. FOXC1 is enriched in the mammary luminal progenitor population, but is not necessary for mouse mammary ductal morphogenesis. Biol Reprod. 2013;89:10 pubmed publisher
  • chromatin immunoprecipitation; mouse
  • western blot; mouse
van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos K, Nieuwenhuis E, et al. FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis. Cell Death Differ. 2013;20:1219-29 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5000
Liu N, Chakrabarti S, Schnell S, Wessendorf M, Gintzler A. Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal morphine antinociception. J Neurosci. 2011;31:11836-45 pubmed publisher
  • chromatin immunoprecipitation; human
Nayak A, Glöckner-Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed publisher
Wei J, Yuen E, Liu W, Li X, Zhong P, Karatsoreos I, et al. Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition. Mol Psychiatry. 2014;19:588-98 pubmed publisher
Liu Q, Wong-Riley M. Postnatal development of brain-derived neurotrophic factor (BDNF) and tyrosine protein kinase B (TrkB) receptor immunoreactivity in multiple brain stem respiratory-related nuclei of the rat. J Comp Neurol. 2013;521:109-29 pubmed publisher
Nakles R, Kallakury B, Furth P. The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. Am J Pathol. 2013;182:1976-85 pubmed publisher
Naville D, Pinteur C, Vega N, Menade Y, Vigier M, Le Bourdais A, et al. Low-dose food contaminants trigger sex-specific, hepatic metabolic changes in the progeny of obese mice. FASEB J. 2013;27:3860-70 pubmed publisher
Zhao J, Imbrie G, Baur W, Iyer L, Aronovitz M, Kershaw T, et al. Estrogen receptor-mediated regulation of microRNA inhibits proliferation of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2013;33:257-65 pubmed publisher
Meitzen J, Luoma J, Boulware M, Hedges V, Peterson B, Tuomela K, et al. Palmitoylation of estrogen receptors is essential for neuronal membrane signaling. Endocrinology. 2013;154:4293-304 pubmed publisher
Nautiyal J, Steel J, Mane M, Oduwole O, Poliandri A, Alexi X, et al. The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development. 2013;140:1079-89 pubmed publisher
Meier-Abt F, Milani E, Roloff T, Brinkhaus H, Duss S, Meyer D, et al. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Res. 2013;15:R36 pubmed
Yeh W, Shioda K, Coser K, Rivizzigno D, McSweeney K, Shioda T. Fulvestrant-induced cell death and proteasomal degradation of estrogen receptor α protein in MCF-7 cells require the CSK c-Src tyrosine kinase. PLoS ONE. 2013;8:e60889 pubmed publisher
Yu C, Tai F, Zeng S, Zhang X. Effects of perinatal daidzein exposure on subsequent behavior and central estrogen receptor α expression in the adult male mouse. Prog Neuropsychopharmacol Biol Psychiatry. 2013;43:157-67 pubmed publisher
Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
Hodgson M, Vanostran G, Alghamdi S, Poppiti R, Agoulnik A, Agoulnik I. Reduced androgen receptor expression accelerates the onset of ERBB2 induced breast tumors in female mice. PLoS ONE. 2013;8:e60455 pubmed publisher
Cardiff R, Hubbard N, Engelberg J, Munn R, Miller C, Walls J, et al. Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers. Lab Invest. 2013;93:480-97 pubmed publisher
Quaynor S, Stradtman E, Kim H, Shen Y, Chorich L, Schreihofer D, et al. Delayed puberty and estrogen resistance in a woman with estrogen receptor α variant. N Engl J Med. 2013;369:164-71 pubmed publisher
Tomasicchio M, Avenant C, Du Toit A, Ray R, Hapgood J. The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor. PLoS ONE. 2013;8:e62895 pubmed publisher
Xiong J, Zeng P, Cheng X, Miao S, Wu L, Zhou S, et al. Lipoxin A4 blocks embryo implantation by controlling estrogen receptor α activity. Reproduction. 2013;145:411-20 pubmed publisher
Gavin K, Cooper E, Hickner R. Estrogen receptor protein content is different in abdominal than gluteal subcutaneous adipose tissue of overweight-to-obese premenopausal women. Metabolism. 2013;62:1180-8 pubmed publisher
Baranda-Avila N, Mendoza-Rodríguez C, Morimoto S, Camacho-Arroyo I, Guerra-Araiza C, Langley E, et al. Agonistic activity of ICI 182 780 on activation of GSK 3β/AKT pathway in the rat uterus during the estrous cycle. Steroids. 2013;78:717-25 pubmed publisher
Matic M, Bryzgalova G, Gao H, Antonson P, Humire P, Omoto Y, et al. Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action. PLoS ONE. 2013;8:e57458 pubmed publisher
McCormick C, Green M, Cameron N, Nixon F, Levy M, Clark R. Deficits in male sexual behavior in adulthood after social instability stress in adolescence in rats. Horm Behav. 2013;63:5-12 pubmed publisher
Morán J, Garrido P, Alonso A, Cabello E, Gonzalez C. 17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats. Exp Gerontol. 2013;48:414-21 pubmed publisher
Medale-Giamarchi C, Lajoie-Mazenc I, Malissein E, Meunier E, Couderc B, Bergé Y, et al. RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor. Breast Cancer Res. 2013;15:R6 pubmed
Christante C, Taboga S, Pinto-Fochi M, Góes R. Maternal obesity disturbs the postnatal development of gonocytes in the rat without impairment of testis structure at prepubertal age. Reproduction. 2013;146:549-58 pubmed publisher
Pallarés M, Baier C, Adrover E, Monteleone M, Brocco M, Antonelli M. Age-dependent effects of prenatal stress on the corticolimbic dopaminergic system development in the rat male offspring. Neurochem Res. 2013;38:2323-35 pubmed publisher
Colitti M, Parillo F. Immunolocalization of estrogen and progesterone receptors in ewe mammary glands. Microsc Res Tech. 2013;76:955-62 pubmed publisher
Navarro A, Del Valle E, Ordóñez C, Martinez E, Perez C, Alonso A, et al. Aging and substitutive hormonal therapy influence in regional and subcellular distribution of ERα in female rat brain. Age (Dordr). 2013;35:821-37 pubmed publisher
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Cotrim C, Fabris V, Doria M, Lindberg K, Gustafsson J, Amado F, et al. Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells. Oncogene. 2013;32:2390-402 pubmed publisher
Pan W, Wong J, Fang E, Chan Y, Ye X, Ng T. Differential inhibitory potencies and mechanisms of the type I ribosome inactivating protein marmorin on estrogen receptor (ER)-positive and ER-negative breast cancer cells. Biochim Biophys Acta. 2013;1833:987-96 pubmed publisher
Signorile P, Baldi F, Bussani R, D'Armiento M, De Falco M, Boccellino M, et al. New evidence of the presence of endometriosis in the human fetus. Reprod Biomed Online. 2010;21:142-7 pubmed publisher
Martinez-Cerdeno V, Noctor S, Kriegstein A. Estradiol stimulates progenitor cell division in the ventricular and subventricular zones of the embryonic neocortex. Eur J Neurosci. 2006;24:3475-88 pubmed
Koszykowska M, Całka J, Gańko M, Jana B. Long-term estradiol-17β administration reduces population of neurons in the sympathetic chain ganglia supplying the ovary in adult gilts. Exp Mol Pathol. 2011;91:353-61 pubmed publisher
Gutierrez S, De Paul A, Petiti J, del Valle Sosa L, Palmeri C, Soaje M, et al. Estradiol interacts with insulin through membrane receptors to induce an antimitogenic effect on lactotroph cells. Steroids. 2008;73:515-27 pubmed publisher
Silberstein G, Van Horn K, Hrabeta-Robinson E, Compton J. Estrogen-triggered delays in mammary gland gene expression during the estrous cycle: evidence for a novel timing system. J Endocrinol. 2006;190:225-39 pubmed
Meyer D, Brinkhaus H, Müller U, Muller M, Cardiff R, Bentires-Alj M. Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors. Cancer Res. 2011;71:4344-51 pubmed publisher
Broberg A, Siddiqui A, Fischer H, Grinnemo K, Wärdell E, Andersson A, et al. Estrogen receptors do not influence angiogenesis after myocardial infarction. Scand Cardiovasc J. 2011;45:215-22 pubmed publisher
Townsend E, Sathish V, Thompson M, Pabelick C, Prakash Y. Estrogen effects on human airway smooth muscle involve cAMP and protein kinase A. Am J Physiol Lung Cell Mol Physiol. 2012;303:L923-8 pubmed publisher
Huang B, Qu Z, Ong C, Tsang Y, Xiao G, Shapiro D, et al. RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α. Oncogene. 2012;31:527-34 pubmed publisher
Signorile P, Campioni M, Vincenzi B, D'Avino A, Baldi A. Rectovaginal septum endometriosis: an immunohistochemical analysis of 62 cases. In Vivo. 2009;23:459-64 pubmed
Townsend E, Thompson M, Pabelick C, Prakash Y. Rapid effects of estrogen on intracellular Ca2+ regulation in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2010;298:L521-30 pubmed publisher
Mafuvadze B, Benakanakere I, López Pérez F, Besch-Williford C, Ellersieck M, Hyder S. Apigenin prevents development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats. Cancer Prev Res (Phila). 2011;4:1316-24 pubmed publisher
Webb M, Emberley E, Lizardo M, Alowami S, Qing G, Alfia'ar A, et al. Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis. BMC Cancer. 2005;5:17 pubmed
Uchida Y, Tokizawa K, Nakamura M, Mori H, Nagashima K. Estrogen in the medial preoptic nucleus of the hypothalamus modulates cold responses in female rats. Brain Res. 2010;1339:49-59 pubmed publisher
Baranda-Avila N, Mendoza-Rodríguez C, Morimoto S, Langley E, Cerbón M. Molecular mechanism of cell proliferation in rodent uterus during the estrous cycle. J Steroid Biochem Mol Biol. 2009;113:259-68 pubmed publisher
Lu H, Lei X, Klaassen C. Gender differences in renal nuclear receptors and aryl hydrocarbon receptor in 5/6 nephrectomized rats. Kidney Int. 2006;70:1920-8 pubmed
Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, et al. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell. 2009;36:340-7 pubmed publisher
Burns K, Li Y, Arao Y, Petrovich R, Korach K. Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms. J Biol Chem. 2011;286:12640-9 pubmed publisher
Muñoz L, Espinosa M, Quintanar-Jurado V, Hidalgo A, Melendez-Zajgla J, Maldonado V. Paradoxial changes in the expression of estrogen receptor alpha in breast cancer multicellular spheroids. Tissue Cell. 2010;42:334-7 pubmed publisher
He Y, Cai B, Yang Y, Liu X, Wan X. Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway. Cancer Sci. 2009;100:1051-61 pubmed publisher
Anesetti G, Lombide P, Chávez-Genaro R. Prepubertal estrogen exposure modifies neurotrophin receptor expression in celiac neurons and alters ovarian innervation. Auton Neurosci. 2009;145:35-43 pubmed publisher
Charitidi K, Frisina R, Vasilyeva O, Zhu X, Canlon B. Expression patterns of estrogen receptors in the central auditory system change in prepubertal and aged mice. Neuroscience. 2010;170:1270-81 pubmed publisher
Klein C, Scoggin K, Ealy A, Troedsson M. Transcriptional profiling of equine endometrium during the time of maternal recognition of pregnancy. Biol Reprod. 2010;83:102-13 pubmed publisher
Alvarez-Delgado C, Mendoza-Rodríguez C, Picazo O, Cerbón M. Different expression of alpha and beta mitochondrial estrogen receptors in the aging rat brain: interaction with respiratory complex V. Exp Gerontol. 2010;45:580-5 pubmed publisher
Schünemann H, Castelli M, Muti P. Systematic reviews for the Journal of Experimental & Clinical Cancer Research: going where the science takes us. J Exp Clin Cancer Res. 2007;26:169-74 pubmed
Visram H, Greer P. 17beta-estradiol and tamoxifen stimulate rapid and transient ERK activationin MCF-7 cells via distinct signaling mechanisms. Cancer Biol Ther. 2006;5:1677-82 pubmed
Jensen M, Schoepfer J, Radimerski T, Massey A, Guy C, Brueggen J, et al. NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Res. 2008;10:R33 pubmed publisher
Wu R, Yuan A, Yuan Q, Guo R, Tai F, Song Z, et al. Comparison of sociability, parental care and central estrogen receptor α expression between two populations of mandarin voles (Microtus mandarinus). J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2011;197:267-77 pubmed publisher
Mastroianni M, Kim S, Kim Y, Esch A, Wagner C, Alexander C. Wnt signaling can substitute for estrogen to induce division of ERalpha-positive cells in a mouse mammary tumor model. Cancer Lett. 2010;289:23-31 pubmed publisher
Baltgalvis K, Greising S, Warren G, Lowe D. Estrogen regulates estrogen receptors and antioxidant gene expression in mouse skeletal muscle. PLoS ONE. 2010;5:e10164 pubmed publisher
CARROLL C, Benakanakere I, Besch-Williford C, Ellersieck M, Hyder S. Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors. Menopause. 2010;17:178-84 pubmed publisher
Ray S, Hou X, Zhou H, Wang H, Das S. Bip is a molecular link between the phase I and phase II estrogenic responses in uterus. Mol Endocrinol. 2006;20:1825-37 pubmed
Jiang Q, Zhang H, Zhang P. ShRNA-mediated gene silencing of MTA1 influenced on protein expression of ER alpha, MMP-9, CyclinD1 and invasiveness, proliferation in breast cancer cell lines MDA-MB-231 and MCF-7 in vitro. J Exp Clin Cancer Res. 2011;30:60 pubmed publisher
Chang H, Balenci L, Okolowsky N, Muller W, Hamel P. Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1. Dev Biol. 2012;370:187-97 pubmed publisher
Alonso A, Moreno M, Ordóñez P, Fernández R, Perez C, Diaz F, et al. Chronic estradiol treatment improves brain homeostasis during aging in female rats. Endocrinology. 2008;149:57-72 pubmed
Manigrasso M, Sawyer R, Marbury D, Flynn E, Maric C. Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2011;301:F634-40 pubmed publisher
Wood C. Cerebral hypoperfusion increases estrogen receptor abundance in the ovine fetal brain and pituitary. Neuroendocrinology. 2008;87:216-22 pubmed
Marosi K, Felszeghy K, Mehra R, Radak Z, Nyakas C. Are the neuroprotective effects of estradiol and physical exercise comparable during ageing in female rats?. Biogerontology. 2012;13:413-27 pubmed publisher
Anderson L, Boulanger C, Smith G, Carmeliet P, Watson C. Stem cell marker prominin-1 regulates branching morphogenesis, but not regenerative capacity, in the mammary gland. Dev Dyn. 2011;240:674-81 pubmed publisher
Takumi K, Iijima N, Iwata K, Higo S, Ozawa H. The effects of gonadal steroid manipulation on the expression of Kiss1 mRNA in rat arcuate nucleus during postnatal development. J Physiol Sci. 2012;62:453-60 pubmed publisher
Alyea R, Watson C. Differential regulation of dopamine transporter function and location by low concentrations of environmental estrogens and 17beta-estradiol. Environ Health Perspect. 2009;117:778-83 pubmed publisher
Ramesh R, Pearl C, At-Taras E, Roser J, Berger T. Ontogeny of androgen and estrogen receptor expression in porcine testis: effect of reducing testicular estrogen synthesis. Anim Reprod Sci. 2007;102:286-99 pubmed
Zhao L, Yu Z, Li Y, Wen X, Ma W, Wang L, et al. Clinical implications of ERβ methylation on sporadic breast cancers in Chinese women. Med Oncol. 2012;29:1569-75 pubmed publisher
He B, Kim T, Kommagani R, Feng Q, Lanz R, Jeong J, et al. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011;152:1047-56 pubmed publisher
Brinckmann M, Kaschina E, Altarche-Xifró W, Curato C, Timm M, Grzesiak A, et al. Estrogen receptor alpha supports cardiomyocytes indirectly through post-infarct cardiac c-kit+ cells. J Mol Cell Cardiol. 2009;47:66-75 pubmed publisher
Asher J, O'Leary K, Rugowski D, Arendt L, Schuler L. Prolactin promotes mammary pathogenesis independently from cyclin D1. Am J Pathol. 2012;181:294-302 pubmed publisher
Alyea R, Watson C. Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux. BMC Neurosci. 2009;10:59 pubmed publisher
Chodankar R, Kwang S, Sangiorgi F, Hong H, Yen H, Deng C, et al. Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. Curr Biol. 2005;15:561-5 pubmed
Vegeto E, Cuzzocrea S, Crisafulli C, Mazzon E, Sala A, Krust A, et al. Estrogen receptor-alpha as a drug target candidate for preventing lung inflammation. Endocrinology. 2010;151:174-84 pubmed publisher
Ridgeway A, McMenamin J, Leder P. P53 levels determine outcome during beta-catenin tumor initiation and metastasis in the mammary gland and male germ cells. Oncogene. 2006;25:3518-27 pubmed
Zama A, Uzumcu M. Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes. Endocrinology. 2009;150:4681-91 pubmed publisher
Ciarloni L, Mallepell S, Brisken C. Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proc Natl Acad Sci U S A. 2007;104:5455-60 pubmed
Quesada A, Romeo H, Micevych P. Distribution and localization patterns of estrogen receptor-beta and insulin-like growth factor-1 receptors in neurons and glial cells of the female rat substantia nigra: localization of ERbeta and IGF-1R in substantia nigra. J Comp Neurol. 2007;503:198-208 pubmed
Li Y, Burns K, Arao Y, Luh C, Korach K. Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro. Environ Health Perspect. 2012;120:1029-35 pubmed publisher
Hasan W, Smith H, Ting A, Smith P. Estrogen alters trkA and p75 neurotrophin receptor expression within sympathetic neurons. J Neurobiol. 2005;65:192-204 pubmed
Schneckenleithner C, Bago-Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, et al. Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget. 2011;2:1043-54 pubmed
Schaub C, Wood C. Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain. Neonatology. 2009;96:115-9 pubmed publisher
Feng Y, Manka D, Wagner K, Khan S. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc Natl Acad Sci U S A. 2007;104:14718-23 pubmed
Heron P, Turchan-Cholewo J, Bruce-Keller A, Wilson M. Estrogen receptor alpha inhibits the estrogen-mediated suppression of HIV transcription in astrocytes: implications for estrogen neuroprotection in HIV dementia. AIDS Res Hum Retroviruses. 2009;25:1071-81 pubmed publisher
Li X, Strauss L, Kaatrasalo A, Mayerhofer A, Huhtaniemi I, Santti R, et al. Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis. Endocrinology. 2006;147:1271-7 pubmed
Buono K, Robinson G, Martin C, Shi S, Stanley P, Tanigaki K, et al. The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy. Dev Biol. 2006;293:565-80 pubmed
Nedungadi T, Briski K. Site-specific effects of intracranial estradiol administration on recurrent insulin-induced hypoglycemia in the ovariectomized female rat. Neuroendocrinology. 2012;96:311-23 pubmed publisher
Chung D, Das S. Mouse primary uterine cell coculture system revisited: ovarian hormones mimic the aspects of in vivo uterine cell proliferation. Endocrinology. 2011;152:3246-58 pubmed publisher
Miermont A, Parrish A, Furth P. Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis. Carcinogenesis. 2010;31:1124-31 pubmed publisher
Kalesnykas G, Roschier U, Puoliväli J, Wang J, Miettinen R. The effect of aging on the subcellular distribution of estrogen receptor-alpha in the cholinergic neurons of transgenic and wild-type mice. Eur J Neurosci. 2005;21:1437-42 pubmed
Alonso A, Del Rey C, Navarro A, Tolivia J, González C. Effects of gestational diabetes mellitus on proteins implicated in insulin signaling in human placenta. Gynecol Endocrinol. 2006;22:526-35 pubmed
Cerliani J, Guillardoy T, Giulianelli S, Vaque J, Gutkind J, Vanzulli S, et al. Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer. Cancer Res. 2011;71:3720-31 pubmed publisher
Cristina C, Diaz-Torga G, Baldi A, Gongora A, Rubinstein M, Low M, et al. Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice. Endocrinology. 2005;146:2952-62 pubmed
Cristina C, Díaz-Torga G, Goya R, Kakar S, Perez-Millán M, Passos V, et al. PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes. Mol Cancer. 2007;6:4 pubmed
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Mazumdar A, Medina D, Kittrell F, Zhang Y, Hill J, Edwards D, et al. The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice. Cancer Prev Res (Phila). 2012;5:1195-202 pubmed publisher
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product information
product name :
ERalpha (MC-20) Antibody
gene name :
size :
200 µg/ml
price :
279 USD
catalog number :
type :
host :
rabbit polyclonal
antigen :
reactive species  :
m, r, h
applications :
epitope :
C-terminal (m)
delivery :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
headquarters: USA