product summary
request information :
company name :
Santa Cruz Biotechnology
product type :
antibody
product name :
Akt1 (B-1)
catalog :
sc-5298
quantity :
200 µg/ml
price :
279 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, rat, mouse
application :
western blot, ELISA, immunoprecipitation, immunocytochemistry, flow cytometry
publications citing this reagent :
total: 22
  1. Son Y, Wang L, Poyil P, Budhraja A, Hitron J, Zhang Z, et al. Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling. Toxicol Appl Pharmacol. 2012;264:153-60 PMID 22884995
  2. Song S, Lee M, Lee J, Jeong H, Kim H, Kim W, et al. Genetic modification of human adipose-derived stem cells for promoting wound healing. J Dermatol Sci. 2012;66:98-107 PMID 22472356
  3. Hung S, Chiang H, Wu C, Hsu M, Chen Y. Effects of herpes simplex virus type 1 infection on immune functions of human neutrophils. J Periodontal Res. 2012;47:635-44 PMID 22471246
  4. Zhang L, Sun S, Zhou J, Liu J, Lv J, Yu X, et al. Knockdown of Akt1 promotes Akt2 upregulation and resistance to oxidative-stress-induced apoptosis through control of multiple signaling pathways. Antioxid Redox Signal. 2011;15:1-17 PMID 21303257
  5. Mukherjee A, Badal Y, Nguyen X, Miller J, Chenna A, Tahir H, et al. Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins. PLoS ONE. 2011;6:e16443 PMID 21297994
  6. Motegi H, Shimo Y, Akiyama T, Inoue J. TRAF6 negatively regulates the Jak1-Erk pathway in interleukin-2 signaling. Genes Cells. 2011;16:179-89 PMID 21155952
  7. Zhang W, Lee J, Kim I, Kim Y, Park J, Myung C. 7-O-methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro. Biol Pharm Bull. 2010;33:1494-9 PMID 20823563
  8. Voutsadakis I, Patrikidou A, Tsapakidis K, Karagiannaki A, Hatzidaki E, Stathakis N, et al. Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. Int J Colorectal Dis. 2010;25:795-804 PMID 20397022
  9. Kalous J, Kubelka M, Solc P, Susor A, Motlik J. AKT (protein kinase B) is implicated in meiotic maturation of porcine oocytes. Reproduction. 2009;138:645-54 PMID 19633130
  10. Yellaturu C, Deng X, Cagen L, Wilcox H, Mansbach C, Siddiqi S, et al. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. J Biol Chem. 2009;284:7518-32 PMID 19158095
product information
product name :
Akt1 (B-1)
Gene Name :
AKT1, AKT2, AKT3
Size :
200 µg/ml
price :
279 USD
catalog number :
sc-5298
type :
monoclonal
host :
mouse monoclonal
Antigen :
Akt1
reactive species :
m, r, h
application :
WB, IP, IF, FCM, ELISA
Epitope :
345-480 (h)
Delivery Time :
Next day delivery in US for orders placed by 3:00 PM; Two day delivery for orders shipped internationally from our US office; Next day delivery to European customers placing orders from our European office
publications citing this reagent :
  1. Sundstrom J, Sundstrom C, Sundstrom S, Fort P, Rauscher R, Gardner T, et al. Phosphorylation site mapping of endogenous proteins: a combined MS and bioinformatics approach. J Proteome Res. 2009;8:798-807 PMID 19125583
  2. Cohen-Kaplan V, Doweck I, Naroditsky I, Vlodavsky I, Ilan N. Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression. Cancer Res. 2008;68:10077-85 PMID 19074873
  3. Hayata K, Sakano K, Nishinaka S. Establishment of new highly insulin-sensitive cell lines and screening of compounds to facilitate glucose consumption. J Pharmacol Sci. 2008;108:348-54 PMID 19008648
  4. Palozza P, Sestito R, Picci N, Lanza P, Monego G, Ranelletti F. The sensitivity to beta-carotene growth-inhibitory and proapoptotic effects is regulated by caveolin-1 expression in human colon and prostate cancer cells. Carcinogenesis. 2008;29:2153-61 PMID 18635524
  5. Casanova J, Carel J, Mention J, Eidenschenk C, Jouanguy E, Alcais A, et al. Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes. J Immunol. 2006;177:8835-43 PMID 17142786
  6. Redondo-Muñoz J, Escobar-Díaz E, Samaniego R, Terol M, García-Marco J, Garcia-Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood. 2006;108:3143-51 PMID 16840734
  7. Saji M, Ringel M, Cheng S, Kato Y, Vasko V, Kruhlak M, et al. AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma. Endocrinology. 2005;146:4456-63 PMID 16002527
  8. Kalous J, Solc P, Baran V, Kubelka M, Schultz R, Motlik J. PKB/AKT is involved in resumption of meiosis in mouse oocytes. Biol Cell. 2006;98:111-23 PMID 15842198
  9. Gingis-Velitski S, Zetser A, Flugelman M, Vlodavsky I, Ilan N. Heparanase induces endothelial cell migration via protein kinase B/Akt activation. J Biol Chem. 2004;279:23536-41 PMID 15044433
  10. Miao H, Zetser A, Bashenko Y, Miao H, Vlodavsky I, Ilan N. Heparanase affects adhesive and tumorigenic potential of human glioma cells. Cancer Res. 2003;63:7733-41 PMID 14633698
  11. Clark R, Miskimins W, Miskimins R. Phosphatidylinositol-3 kinase p85 enhances expression from the myelin basic protein promoter in oligodendrocytes. J Neurochem. 2002;83:565-73 PMID 12390518
  12. Yellaturu C, Bhanoori M, Neeli I, Rao G. N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A. J Biol Chem. 2002;277:40148-55 PMID 12171932
company information
Santa Cruz Biotechnology
2145 Delaware Avenue
Santa Cruz, CA 95060
scbt@scbt.com
www.scbt.com
1.800.457.3801
Headquarters: USA