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product summary
company name :
Rockland Immunochemicals
product type :
protein
product name :
IL-35 EBI3 Human Recombinant Protein
catalog :
009-001-B66
quantity :
20 µg
price :
244.00 USD
product information
Catalog Number :
009-001-B66
Name :
EBI-3 Human Recombinant Protein - 009-001-B66
Display Name :
IL-35 EBI3 Human Recombinant Protein
Application Note :
EBI-3 is suitable as a control for polyclonal or monoclonal anti-EBI-3 in immunological assays. The product is lyophilized from a sterile filtered aqueous solution of 0.1% TFA and 0.5% mannitol.
Buffer :
0.1% Trifluoroacetic acid
Concentration Value :
0.1 mg/mL
Concentration Definition :
by UV absorbance at 280 nm
Conjugation :
(None)
Size :
20 µg
Default Unit :
µg
Expiration :
Expiration date is six (6) months from date of opening.
Gene Name :
IL-27B
Host Animal :
Other - E.coli
General Disclaimer Note :
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
Other Performance Data :
Biological Activity: Assay data for Human recombinant EBI-3 is based upon qualitative binding to anti-EBI-3 antibody.
Endotoxin Level: Measured by LAL is <0.01ng/µg or <0.1EU/µg.
Packing Type :
Ambient
Physical State :
Lyophilized
Purity and Specificity :
Recombinant protein corresponds to amino acids 21 to 229 of mature human EBI3. Purity is greater than 90% as determined by reducing and non-reducing SDS-PAGE and by analytical HPLC.
Reconstitution Buffer :
Restore with deionized water (or equivalent)
Reconstitution Volume :
20µl (20-200µl)
Species of Origin :
Human
Species Reactivity :
Human
Stabilizer :
0.5% Mannitol
Storage :
Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
Synonyms :
Epstein-Barr virus induced 3 protein, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B cytokine, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI-3, EBI3, IL-35, IL35
Background :
Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant Human EBI is a non-glycosylated polypeptide chain consisting of 209 amino acids with a molecular weight of 23.3 kDa.
General Reference :
Kempe,S., Heinz,P., Kokai,E., Devergne,O., Marx,N. and Wirth,T. (2009) Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques . Am. J. Pathol. 175 (1), 440-447. PUBMED 19556516
Low Endotoxin :
Yes
PSC Format :
Recombinant Protein
PSC Type :
Cytokine, Interleukin or Growth Factor
Sample Size :
No
Other :
User Optimized
Category :
Proteins and Peptides
Conjugation Name :
Unconjugated
2019 Price :
244.00 USD
UniProt :
Q14213
Primary Image Name :
EBI-3 Human Recombinant Protein - SDS-PAGE
company information

Rockland Immunochemicals
321 Jones Blvd
Pottstown, PA 19464
Pottstown, PA 19464
Info@rockland-inc.com
https://rockland-inc.com484-791-3823
headquarters: USA
Rockland Immunochemicals, Inc. produces Phosho-Site Specific Antibodies and Antibody based tools for basic, applied and clinical research. Our laboratory is located west of Philadelphia, Pennsylvania, USA. The technology base of the organization is the experience of its staff scientists in the production and purification of a wide range of antibodies through monoclonal & polyclonal antibody techniques utilizing in vitro and in vivo methods. Rockland's antibodies are suited for individuals performing Western Blotting, ELISA, Immunohistochemistry, Fluorescent Microscopy, High Content Screening and diagnostic kit production. Primary antibodies include Akt Pathway, Apolipoproteins, Apoptosis/Cell Cycle, Cytokines, Cell Signaling, Enzymes, Extracellular Matrix, Transcription Factors (NFkB) and Ubiquitin.
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