Mouse IL-10 Antibody | R&D Systems MAB417 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-10 Antibody

catalog :

MAB417

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

JES052A5

reactivity :

human, mouse

application :

western blot, ELISA, neutralization

citations: 37

Reference
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Zhao Y, Wang J, Min Z, Peng L, Qi S, Lin W. I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis. Mediators Inflamm. 2020;2020:6947482 pubmed publisher
Wang B, Wu S, Ma Z, Wang T, Yang C. BMSCs pre-treatment ameliorates inflammation-related tissue destruction in LPS-induced rat DIC model. Cell Death Dis. 2018;9:1024 pubmed publisher
Tian L, Song S, Zhu B, Liu S. Electroacupuncture at ST-36 Protects Interstitial Cells of Cajal via Sustaining Heme Oxygenase-1 Positive M2 Macrophages in the Stomach of Diabetic Mice. Oxid Med Cell Longev. 2018;2018:3987134 pubmed publisher
Dyck S, Kataria H, Alizadeh A, Santhosh K, Lang B, Silver J, et al. Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury. J Neuroinflammation. 2018;15:90 pubmed publisher
Foubert P, Kaneda M, Varner J. PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression. Cancer Immunol Res. 2017;5:957-968 pubmed publisher
Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed publisher
Nascimento D, Melo P, Piñeros A, Ferreira R, Cólon D, Donate P, et al. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nat Commun. 2017;8:14919 pubmed publisher
Dawicki W, Li C, Town J, Zhang X, Gordon J. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3+CD49b-Foxp3- regulatory T cells. J Allergy Clin Immunol. 2017;139:1608-1620.e3 pubmed publisher
Byrne A, Weiss M, Mathie S, Walker S, Eames H, Saliba D, et al. A critical role for IRF5 in regulating allergic airway inflammation. Mucosal Immunol. 2017;10:716-726 pubmed publisher
Hu Y, Qin C, Zheng G, Lai D, Tao H, Zhang Y, et al. Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response. Mediators Inflamm. 2016;2016:3735452 pubmed publisher
Lim J, Im K, Lee E, Kim N, Nam Y, Jeon Y, et al. Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis. Sci Rep. 2016;6:26851 pubmed publisher
Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, et al. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. PLoS Pathog. 2015;11:e1004607 pubmed publisher
McKelvey R, Berta T, Old E, Ji R, Fitzgerald M. Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. J Neurosci. 2015;35:457-66 pubmed publisher
Ohama H, Asai A, Ito I, Suzuki S, Kobayashi M, Higuchi K, et al. M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections. Am J Pathol. 2015;185:420-31 pubmed publisher
Lalani A, Moore C, Luo C, Kreider B, Liu Y, Morse H, et al. Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice. J Immunol. 2015;194:334-48 pubmed publisher
Hsu K, Chung Y, Endoh Y, Geczy C. TLR9 ligands induce S100A8 in macrophages via a STAT3-dependent pathway which requires IL-10 and PGE2. PLoS ONE. 2014;9:e103629 pubmed publisher
Kimura T, Sugaya M, Blauvelt A, Okochi H, Sato S. Delayed wound healing due to increased interleukin-10 expression in mice with lymphatic dysfunction. J Leukoc Biol. 2013;94:137-45 pubmed publisher
Wang Y, Sung W, Wu T, Wang L, Chien W, Cheng Y, et al. Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS ONE. 2012;7:e39525 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Lu H, Wagner W, Gad E, Yang Y, Duan H, Amon L, et al. Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade. J Immunol. 2010;184:5360-7 pubmed publisher
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product information

brand :

R&D Systems

master code :

MAB417

SKU :

MAB417-100

product name :

Mouse IL-10 Antibody

description :

The Mouse IL-10 Antibody from R&D Systems is a rat monoclonal antibody to IL-10. This antibody reacts with mouse. The Mouse IL-10 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

IL-10

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

JES052A5

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IL-10, Accession # P18893

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-10 in sandwich ELISAs and Western blots. In sandwich ELISAs, less than 8% cross-reactivity with recombinant rat IL-10 and 1% cross-reactivity with recombinant cotton rat IL-10 is observed. In sandwich ELISAs, no cross-reactivity with recombinant human (rh) IL-10, recombinant mouse IL-10 R, rhIL-10 R, recombinant canine IL-10, recombinant feline IL-10, or recombinant porcine IL-10 is observed.

gene symbol :

IL10

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB417

accessionNumbers :

P18893

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.