product summary
request information :
company name :
R and D Systems
product type :
ELISA/assay
product name :
Human IL-6 Quantikine ELISA Kit
catalog :
D6050
quantity :
1 Kit
price :
495 USD
more info or order :
citations: 180
Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, et al. A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism. Mol Autism. 2015;6:18 pubmed publisher
Osei-Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M. The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses. Infect Immun. 2015;83:1507-22 pubmed publisher
McElvaney O, O'Reilly N, White M, Lacey N, Pohl K, Gerlza T, et al. The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis. Mol Immunol. 2015;63:550-8 pubmed publisher
Kant P, Perry S, Dexter S, Race A, Loadman P, Hull M. Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass. Obesity (Silver Spring). 2014;22:202-10 pubmed publisher
Portilla J, Moreno-Pérez Ó, Serna-Candel C, Escoín C, Alfayate R, Reus S, et al. Vitamin D insufficiency and subclinical atherosclerosis in non-diabetic males living with HIV. J Int AIDS Soc. 2014;17:18945 pubmed publisher
Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, et al. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy. Br J Cancer. 2014;110:26-33 pubmed publisher
Campbell M, Walker M, Trenell M, Luzio S, Dunseath G, Tuner D, et al. Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in type 1 diabetes patients: a randomised clinical trial. PLoS ONE. 2014;9:e97143 pubmed publisher
Ekström E, Bergenfelz C, von Bulow V, Serifler F, Carlemalm E, Jonsson G, et al. WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells. Mol Cancer. 2014;13:88 pubmed publisher
Tu B, Peng Z, Fan Q, Du L, Yan W, Tang T. Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-β/Smad2/3 pathway. Exp Cell Res. 2014;320:164-73 pubmed publisher
Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, et al. Cleaved/associated TLR3 represents the primary form of the signaling receptor. J Immunol. 2013;190:764-73 pubmed publisher
Lepiller Q, Abbas W, Kumar A, Tripathy M, Herbein G. HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes. PLoS ONE. 2013;8:e59591 pubmed publisher
Todd J, Simpson P, Estis J, Torres V, Wub A. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. Cytokine. 2013;64:660-5 pubmed publisher
Saadat H, Ziai S, Ghanemnia M, Namazi M, Safi M, Vakili H, et al. Opium addiction increases interleukin 1 receptor antagonist (IL-1Ra) in the coronary artery disease patients. PLoS ONE. 2012;7:e44939 pubmed publisher
Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, et al. Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model. Am J Pathol. 2012;181:1540-59 pubmed publisher
Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, et al. TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity. J Biol Chem. 2012;287:32216-21 pubmed publisher
Suzuki M, Mihara M. Adiponectin induces CCL20 expression synergistically with IL-6 and TNF-α in THP-1 macrophages. Cytokine. 2012;58:344-50 pubmed publisher
Silverman A, Nakata R, Shimada H, Sposto R, DeClerck Y. A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma. Cancer Res. 2012;72:2228-38 pubmed publisher
Petrovas C, Yamamoto T, Gerner M, Boswell K, Wloka K, Smith E, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122:3281-94 pubmed publisher
Ekström M, Liska J, Eriksson P, Sverremark-Ekström E, Tornvall P. Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue. Thromb Haemost. 2012;108:485-92 pubmed publisher
Paine R, Standiford T, Dechert R, Moss M, Martin G, Rosenberg A, et al. A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury. Crit Care Med. 2012;40:90-7 pubmed publisher
Wang J, Shih K, Liou J, Wu Y, Chang A, Wang K, et al. Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model. PLoS ONE. 2012;7:e31368 pubmed publisher
Grote V, Kaaks R, Nieters A, Tjønneland A, Halkjær J, Overvad K, et al. Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort. Br J Cancer. 2012;106:1866-74 pubmed publisher
Bianchetti L, Marini M, Isgrò M, Bellini A, Schmidt M, Mattoli S. IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma. Biochem Biophys Res Commun. 2012;426:116-21 pubmed publisher
Jaedicke K, Taylor J, Preshaw P. Validation and quality control of ELISAs for the use with human saliva samples. J Immunol Methods. 2012;377:62-5 pubmed publisher
Kulbe H, Chakravarty P, Leinster D, Charles K, Kwong J, Thompson R, et al. A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment. Cancer Res. 2012;72:66-75 pubmed publisher
Shimizu M, Yachie A. Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages. Cytokine. 2012;60:226-32 pubmed publisher
Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G. Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses. Innate Immun. 2012;18:531-40 pubmed publisher
Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, et al. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis. Blood. 2012;120:4058-67 pubmed publisher
Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, et al. Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis. Atherosclerosis. 2009;203:503-8 pubmed publisher
Madden L, Zandonatti M, Flynn C, Taffe M, Marcondes M, Schmitz J, et al. CD8+ cell depletion amplifies the acute retroviral syndrome. J Neurovirol. 2004;10:58-66 pubmed
Sheu J, Chen M, Lue K, Cheng S, Lee I, Chen S, et al. Serum and urine levels of interleukin-6 and interleukin-8 in children with acute pyelonephritis. Cytokine. 2006;36:276-82 pubmed
Wilkinson T, Donaldson G, Johnston S, Openshaw P, Wedzicha J. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2006;173:871-6 pubmed
Solheim S, Pettersen A, Arnesen H, Seljeflot I. No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease. Thromb Haemost. 2006;96:660-4 pubmed
Shariat S, Karam J, Walz J, Roehrborn C, Montorsi F, Margulis V, et al. Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Clin Cancer Res. 2008;14:3785-91 pubmed publisher
Holt H, Wild S, Wood P, Zhang J, Darekar A, Dewbury K, et al. Non-esterified fatty acid concentrations are independently associated with hepatic steatosis in obese subjects. Diabetologia. 2006;49:141-8 pubmed
Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, et al. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria. Transplantation. 2009;88:1109-16 pubmed publisher
Poulsen T, Andersen L, Steinbruchel D, Gøtze J, Jørgensen O, Olsen N. Two large preoperative doses of erythropoietin do not reduce the systemic inflammatory response to cardiac surgery. J Cardiothorac Vasc Anesth. 2009;23:316-23 pubmed publisher
Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M. Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls. Atherosclerosis. 2006;189:458-63 pubmed
Ichiyama T, Isumi H, Yoshitomi T, Nishikawa M, Matsubara T, Furukawa S. NF-kappaB activation in cerebrospinal fluid cells from patients with meningitis. Neurol Res. 2002;24:709-12 pubmed
Dossus L, Becker S, Achaintre D, Kaaks R, Rinaldi S. Validity of multiplex-based assays for cytokine measurements in serum and plasma from "non-diseased" subjects: comparison with ELISA. J Immunol Methods. 2009;350:125-32 pubmed publisher
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, et al. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood. 2008;111:3155-62 pubmed publisher
Tousoulis D, Antoniades C, Nikolopoulou A, Koniari K, Vasiliadou C, Marinou K, et al. Interaction between cytokines and sCD40L in patients with stable and unstable coronary syndromes. Eur J Clin Invest. 2007;37:623-8 pubmed
Ogawa J, Sasahara A, Yoshida T, Sira M, Futatani T, Kanegane H, et al. Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants. Early Hum Dev. 2004;77:67-75 pubmed
Kaneyama K, Segami N, Nishimura M, Sato J, Fujimura K, Yoshimura H. The ideal lavage volume for removing bradykinin, interleukin-6, and protein from the temporomandibular joint by arthrocentesis. J Oral Maxillofac Surg. 2004;62:657-61 pubmed
Choo-Wing R, Nedrelow J, Homer R, Elias J, Bhandari V. Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007;293:L142-50 pubmed
Bellinghausen I, Brand P, Böttcher I, Klostermann B, Knop J, Saloga J. Production of interleukin-13 by human dendritic cells after stimulation with protein allergens is a key factor for induction of T helper 2 cytokines and is associated with activation of signal transducer and activator of transcription-6. Immunology. 2003;108:167-76 pubmed
Fichorova R, Richardson-Harman N, Alfano M, Belec L, Carbonneil C, Chen S, et al. Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study. Anal Chem. 2008;80:4741-51 pubmed publisher
Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S. Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients. Arch Dermatol Res. 2011;303:451-5 pubmed publisher
Sandberg W, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad F, et al. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Circ Res. 2009;104:60-8 pubmed publisher
Bronte-Tinkew D, Terebiznik M, Franco A, Ang M, Ahn D, Mimuro H, et al. Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. Cancer Res. 2009;69:632-9 pubmed publisher
Ziesché E, Scheiermann P, Bachmann M, Sadik C, Hofstetter C, Zwissler B, et al. Dexamethasone suppresses interleukin-22 associated with bacterial infection in vitro and in vivo. Clin Exp Immunol. 2009;157:370-6 pubmed publisher
Attur M, Dave M, Clancy R, Patel I, Abramson S, Amin A. Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins. J Immunol. 2000;164:2684-91 pubmed
Song W, Tai Y, Tian Z, Hideshima T, Chauhan D, Nanjappa P, et al. HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia. 2011;25:161-8 pubmed publisher
Messmer D, Jacque J, Santisteban C, Bristow C, Han S, Villamide-Herrera L, et al. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. J Immunol. 2002;169:4172-82 pubmed
Kim P, Woods C, Dutcher L, Georgoff P, Rosenberg A, Mican J, et al. Increased prevalence of albuminuria in HIV-infected adults with diabetes. PLoS ONE. 2011;6:e24610 pubmed publisher
Richards P, Nowell M, Horiuchi S, McLoughlin R, Fielding C, Grau S, et al. Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis Rheum. 2006;54:1662-72 pubmed
Sadeghi M, Süsal C, Daniel V, Naujokat C, Zimmermann R, Huth-Kühne A, et al. Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy. AIDS Res Hum Retroviruses. 2007;23:886-90 pubmed
Petrucci M, Ricciardi M, Gregorj C, Ciapponi L, Savino R, Ciliberto G, et al. Effects of IL-6 variants in multiple myeloma: growth inhibition and induction of apoptosis in primary cells. Leuk Lymphoma. 2002;43:2369-75 pubmed
Stubner S, Schön T, Padberg F, Teipel S, Schwarz M, Haslinger A, et al. Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130. Neurosci Lett. 1999;259:145-8 pubmed
López-Karpovitch X, Barrales-Benitez O, Flores M, Piedras J. Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia. Cytokine. 2002;20:154-62 pubmed
Khan K, Masuzaki H, Fujishita A, Hamasaki T, Kitajima M, Hasuo A, et al. Association of interleukin-6 and estradiol with hepatocyte growth factor in peritoneal fluid of women with endometriosis. Acta Obstet Gynecol Scand. 2002;81:764-71 pubmed
Kurooka M, Kaneda Y. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res. 2007;67:227-36 pubmed
Miyamae T, Marinov A, Sowders D, Wilson D, Devlin J, Boudreau R, et al. Follistatin-like protein-1 is a novel proinflammatory molecule. J Immunol. 2006;177:4758-62 pubmed
Yagami A, Orihara K, Morita H, Futamura K, Hashimoto N, Matsumoto K, et al. IL-33 mediates inflammatory responses in human lung tissue cells. J Immunol. 2010;185:5743-50 pubmed publisher
Wang Z, Yang D, Chen Q, Leifer C, Segal D, Su S, et al. Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways. Exp Hematol. 2006;34:1115-24 pubmed
Mabilleau G, Sabokbar A. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE. 2009;4:e4173 pubmed publisher
Pagura S, Thomas S, Woodhouse L, Ezzat S, Marks P. Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men. J Orthop Res. 2005;23:397-405 pubmed
Verma S, Kumar M, Nerurkar V. Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. J Gen Virol. 2011;92:507-15 pubmed publisher
Chan D, Watts G, Ng T, Uchida Y, Sakai N, Yamashita S, et al. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism. Clin Chem. 2005;51:578-85 pubmed
Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U. Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts. Eur J Appl Physiol. 2001;86:48-52 pubmed
Samnegard A, Hulthe J, Silveira A, Ericsson C, Hamsten A, Eriksson P. Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients. Atherosclerosis. 2009;202:550-6 pubmed publisher
Cotler S, Reddy K, McCone J, Wolfe D, Liu A, Craft T, et al. An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon. J Interferon Cytokine Res. 2001;21:1011-9 pubmed
Johannsen A, Rylander G, Söder B, Asberg M. Dental plaque, gingival inflammation, and elevated levels of interleukin-6 and cortisol in gingival crevicular fluid from women with stress-related depression and exhaustion. J Periodontol. 2006;77:1403-9 pubmed
Quint J, Donaldson G, Goldring J, Baghai-Ravary R, Hurst J, Wedzicha J. Serum IP-10 as a biomarker of human rhinovirus infection at exacerbation of COPD. Chest. 2010;137:812-22 pubmed publisher
Rampino T, Collesi C, Gregorini M, Maggio M, Soccio G, Guallini P, et al. Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells. J Am Soc Nephrol. 2002;13:649-57 pubmed
McGuire T, Brusnahan S, Bilek L, Jackson J, KESSINGER M, Berger A, et al. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells. Obesity (Silver Spring). 2011;19:2130-6 pubmed publisher
Caine G, Stonelake P, Lip G, Blann A. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007;248:131-6 pubmed
Bateman A, McArdle F, Walsh T. Time course of anemia during six months follow up following intensive care discharge and factors associated with impaired recovery of erythropoiesis. Crit Care Med. 2009;37:1906-12 pubmed publisher
Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, et al. Gene expression profiling of human skeletal muscle in response to stabilized weight loss. Am J Clin Nutr. 2008;88:125-32 pubmed
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson P, et al. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood. 2006;108:947-55 pubmed
Rodier F, Coppe J, Patil C, Hoeijmakers W, Muñoz D, Raza S, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009;11:973-9 pubmed publisher
Ehling A, Schaffler A, Herfarth H, Tarner I, Anders S, Distler O, et al. The potential of adiponectin in driving arthritis. J Immunol. 2006;176:4468-78 pubmed
Makis A, Hatzimichael E, Stebbing J, Bourantas K. C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease. Arch Intern Med. 2006;166:366-8 pubmed
Jacobsson B, Mattsby-Baltzer I, Hagberg H. Interleukin-6 and interleukin-8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes. BJOG. 2005;112:719-24 pubmed
Bertho J, Prat M, Frick J, Demarquay C, Gaugler M, Dudoignon N, et al. Application of autologous hematopoietic cell therapy to a nonhuman primate model of heterogeneous high-dose irradiation. Radiat Res. 2005;163:557-70 pubmed
Aranha C, Gupta S, Reddy K. Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits. Cytokine. 2008;43:63-70 pubmed publisher
Anderson S, Williams A, Brown J, Newton S, Simsova M, Nicol M, et al. Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing. Am J Respir Crit Care Med. 2006;173:1038-42 pubmed
Gómez-Torres M, Acién P, Campos A, Velasco I. Embryotoxicity of peritoneal fluid in women with endometriosis. Its relation with cytokines and lymphocyte populations. Hum Reprod. 2002;17:777-81 pubmed
Martis L, Patel M, Giertych J, Mongoven J, Taminne M, Perrier M, et al. Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution. Lancet. 2005;365:588-94 pubmed
Dadfar E, Jacobson S, Lundahl J. Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production. Clin Exp Immunol. 2007;148:573-82 pubmed
Basu S, Aballa T, Ferrell S, Lynne C, Brackett N. Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J Androl. 2004;25:250-4 pubmed
Erickson D, Xie S, Bhavanandan V, Wheeler M, Hurst R, Demers L, et al. A comparison of multiple urine markers for interstitial cystitis. J Urol. 2002;167:2461-9 pubmed
Zhu S, Su G, Meng Q. Inhibitory effects of micronized fenofibrate on carotid atherosclerosis in patients with essential hypertension. Clin Chem. 2006;52:2036-42 pubmed
Wang B, Wood I, Trayhurn P. Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes. J Endocrinol. 2008;198:127-34 pubmed publisher
Matsushima A, Ogura H, Koh T, Fujita K, Yoshiya K, Sumi Y, et al. Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome. J Trauma. 2004;56:259-64 pubmed
Claessens Y, Fontenay M, Pène F, Chiche J, Guesnu M, Hababou C, et al. Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock. Am J Respir Crit Care Med. 2006;174:51-7 pubmed
Auguet T, Quintero Y, Terra X, Martínez S, Lucas A, Pellitero S, et al. Upregulation of lipocalin 2 in adipose tissues of severely obese women: positive relationship with proinflammatory cytokines. Obesity (Silver Spring). 2011;19:2295-300 pubmed publisher
Rudack C, Sachse F, Albert N, Becker K, von Eiff C. Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases. J Immunol. 2009;183:7592-601 pubmed publisher
Orfanos S, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, et al. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Crit Care Med. 2007;35:199-206 pubmed
Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A. Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure. Eur Respir J. 2005;25:797-803 pubmed
Kabagambe E, Ordovas J, Tsai M, Borecki I, Hopkins P, Glasser S, et al. Smoking, inflammatory patterns and postprandial hypertriglyceridemia. Atherosclerosis. 2009;203:633-9 pubmed publisher
Bengtson S, Phagoo S, Norrby-Teglund A, Påhlman L, Morgelin M, Zuraw B, et al. Kinin receptor expression during Staphylococcus aureus infection. Blood. 2006;108:2055-63 pubmed
Vergne-Salle P, Leger D, Bertin P, Treves R, Beneytout J, Liagre B. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes. Cytokine. 2005;31:335-48 pubmed
Kim S, Veena M, Basak S, Han E, Tajima T, Gjertson D, et al. Curcumin treatment suppresses IKKβ kinase activity of salivary cells of patients with head and neck cancer: a pilot study. Clin Cancer Res. 2011;17:5953-61 pubmed publisher
Ara T, Song L, Shimada H, Keshelava N, Russell H, Metelitsa L, et al. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009;69:329-37 pubmed publisher
Heep A, Schaller C, Rittmann N, Himbert U, Marklein G, Bartmann P. Multiple brain abscesses in an extremely preterm infant: treatment surveillance with interleukin-6 in the CSF. Eur J Pediatr. 2004;163:44-5 pubmed
Yates S, Burgess L, Kocsis-Angle J, Antal J, Dority M, Embury P, et al. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J Neurochem. 2000;74:1017-25 pubmed
Doucet M, Russell A, Leger B, Debigare R, Joanisse D, Caron M, et al. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007;176:261-9 pubmed
Vidyarani M, Selvaraj P, Jawahar M, Narayanan P. 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine. 2007;40:128-34 pubmed
Armitage J, Lindsey N, Homer-Vanniasinkam S. The role of endothelial cell reactive antibodies in peripheral arterial disease. Eur J Vasc Endovasc Surg. 2006;31:170-5 pubmed
Marquez-Martin A, De La Puerta R, Fernandez-Arche A, Ruiz-Gutierrez V, Yaqoob P. Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells. Cytokine. 2006;36:211-7 pubmed
Yee L, Williams N, Wen P, Young D, Lester J, Johnson M, et al. Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers. Clin Cancer Res. 2007;13:246-52 pubmed
Ciszek M, Paczek L, Bartłomiejczyk I, Mucha K. Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria. Transplantation. 2006;81:1653-7 pubmed
Chen C, Yang K, Chen M, Chen H, Lin M, Lee Y, et al. Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome. Am J Respir Crit Care Med. 2009;180:751-60 pubmed publisher
Mizutani K, Sud S, Pienta K. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. J Cell Biochem. 2009;106:563-9 pubmed publisher
Rhind S, Crnko N, Baker A, Morrison L, Shek P, Scarpelini S, et al. Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients. J Neuroinflammation. 2010;7:5 pubmed publisher
Chase J, Celli J, Bosio C. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect Immun. 2009;77:180-95 pubmed publisher
Lankford K, Mosunjac M, Hillyer C. Effects of UVB radiation on cytokine generation, cell adhesion molecules, and cell activation markers in T-lymphocytes and peripheral blood HPCs. Transfusion. 2000;40:361-7 pubmed
Chuang C, Hung C, Tsai M, Yeh T, Chuang Y. High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?. Crit Care Med. 2004;32:734-9 pubmed
Lachmann H, Lowe P, Felix S, Rordorf C, Leslie K, Madhoo S, et al. In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. J Exp Med. 2009;206:1029-36 pubmed publisher
Weigert J, Neumeier M, Wanninger J, Schober F, Sporrer D, Weber M, et al. Adiponectin upregulates monocytic activin A but systemic levels are not altered in obesity or type 2 diabetes. Cytokine. 2009;45:86-91 pubmed publisher
Liem-Moolenaar M, Cerneus D, Molloy C, End D, Brown K, de Kam M, et al. Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans. Clin Pharmacol Ther. 2008;84:481-7 pubmed
Kourea K, Parissis J, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, et al. Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure. Atherosclerosis. 2008;199:215-21 pubmed
Jacobs M, van Greevenbroek M, van der Kallen C, Ferreira I, Blaak E, Feskens E, et al. Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study. Eur J Clin Invest. 2009;39:437-44 pubmed publisher
Sheikine Y, Bang C, Nilsson L, Samnegard A, Hamsten A, Jonasson L, et al. Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease. Atherosclerosis. 2006;188:462-6 pubmed
Moseman E, Liang X, Dawson A, Panoskaltsis-Mortari A, Krieg A, Liu Y, et al. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J Immunol. 2004;173:4433-42 pubmed
Freund A, Patil C, Campisi J. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J. 2011;30:1536-48 pubmed publisher
Carstanjen D, Regenfus M, Muller C, Salama A. Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response. Exp Hematol. 2001;29:812-21 pubmed
Hsu Y, Li H, Hsieh M, Liu M, Huang K, Chin L, et al. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis Rheum. 2006;54:2722-33 pubmed
Marx N, Froehlich J, Siam L, Ittner J, Wierse G, Schmidt A, et al. Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease. Arterioscler Thromb Vasc Biol. 2003;23:283-8 pubmed
Ren Y, Lin C, Li Z, Chen X, Huang X, Lui V, et al. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Histopathology. 2005;46:659-67 pubmed
Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, et al. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial. AIDS. 2009;23:929-39 pubmed
Patel I, Vlahos I, Wilkinson T, Lloyd-Owen S, Donaldson G, Wilks M, et al. Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2004;170:400-7 pubmed
Bovolenta C, Pilotti E, Mauri M, Turci M, Ciancianaini P, Fisicaro P, et al. Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor. Blood. 2002;99:224-31 pubmed
Montero I, Orbe J, Varo N, Beloqui O, Monreal J, Rodriguez J, et al. C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis. J Am Coll Cardiol. 2006;47:1369-78 pubmed
Amiable N, Tat S, Lajeunesse D, Duval N, Pelletier J, Martel-Pelletier J, et al. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone. 2009;44:1143-50 pubmed publisher
Mian M, Lauzon N, Stampfli M, Mossman K, Ashkar A. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J Leukoc Biol. 2008;83:774-84 pubmed
Nikasinovic L, Just J, Sahraoui F, Seta N, Grimfeld A, Momas I. Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children. J Allergy Clin Immunol. 2006;117:1382-8 pubmed
Lecube A, Hernandez C, Genesca J, Simo R. Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study. Diabetes Care. 2006;29:1096-101 pubmed
Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N. The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection. Fertil Steril. 2008;90:60-4 pubmed
Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, Holy X, et al. Mesenchymal stem cell abnormalities in patients with multiple myeloma. Leuk Lymphoma. 2007;48:2032-41 pubmed
Le Quement C, Guenon I, Gillon J, Lagente V, Boichot E. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2008;294:L1076-84 pubmed publisher
Seeber B, Sammel M, Fan X, Gerton G, Shaunik A, Chittams J, et al. Panel of markers can accurately predict endometriosis in a subset of patients. Fertil Steril. 2008;89:1073-81 pubmed
Keller E, Binkley N, Stebler B, Hall D, Johnston G, Zhang J, et al. Ovariectomy does not induce osteopenia through interleukin-6 in rhesus monkeys (Macaca mulatta). Bone. 2000;26:55-62 pubmed
Henkel J, Engelhardt J, Siklos L, Simpson E, Kim S, Pan T, et al. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol. 2004;55:221-35 pubmed
Lee M, Hooper L, Kump L, Hayashi K, Nussenblatt R, Hooks J, et al. Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling. Clin Exp Immunol. 2007;147:71-80 pubmed
Niu K, Huang W, Lin M, Huang K. Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits. Eur J Pharmacol. 2009;606:240-5 pubmed publisher
McNamara P, Flanagan B, Selby A, Hart C, Smyth R. Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis. Eur Respir J. 2004;23:106-12 pubmed
Oh J, Kim M, Shin M, Wee W, Lee J. Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells. Cytokine. 2009;46:100-3 pubmed publisher
Minetto M, Rainoldi A, Gazzoni M, Terzolo M, Borrione P, Termine A, et al. Differential responses of serum and salivary interleukin-6 to acute strenuous exercise. Eur J Appl Physiol. 2005;93:679-86 pubmed
Nathwani A, Gray J, Ng C, Zhou J, Spence Y, Waddington S, et al. Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver. Blood. 2006;107:2653-61 pubmed
Peterson M, Schlievert P. Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells. Biochemistry. 2006;45:2387-97 pubmed
Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol. 2010;126:962-8, 968.e1-6 pubmed publisher
Welty-Wolf K, Carraway M, Ghio A, Kantrow S, Huang Y, Piantadosi C. Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy. Shock. 2000;13:404-9 pubmed
Perez-Andres M, Almeida J, Martin-Ayuso M, de las Heras N, Moro M, Martín-Nuñez G, et al. Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease. Int J Cancer. 2009;124:367-75 pubmed publisher
Hsieh C, Lu J, Chen S, Lan C, Chow W, Tang R. Cerebrospinal fluid levels of interleukin-6 and interleukin-12 in children with meningitis. Childs Nerv Syst. 2009;25:461-5 pubmed publisher
Wilkinson T, Hurst J, Perera W, Wilks M, Donaldson G, Wedzicha J. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest. 2006;129:317-24 pubmed
Chen L, Tager I, Peden D, Christian D, Ferrando R, Welch B, et al. Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects. Chest. 2004;125:2328-35 pubmed
Ferrandina G, Ranelletti F, Legge F, Salutari V, Martinelli E, Fattorossi A, et al. Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer. Clin Cancer Res. 2006;12:2055-60 pubmed
Wang T, Chen W, Cheng W, Lin J, Chen M, Lee Y. Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome. Am J Cardiol. 2006;98:1057-62 pubmed
Paulsson J, Dadfar E, Held C, Jacobson S, Lundahl J. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b. Clin Exp Immunol. 2008;153:196-204 pubmed publisher
Marme A, Strauss G, Bastert G, Grischke E, Moldenhauer G. Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma. Int J Cancer. 2002;101:183-9 pubmed
Hatfield K, Ryningen A, Corbascio M, Bruserud O. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int J Cancer. 2006;119:2313-21 pubmed
Magne D, Palmer G, Barton J, Mezin F, Talabot-Ayer D, Bas S, et al. The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. Arthritis Res Ther. 2006;8:R80 pubmed
Hampel H, Teipel S, Padberg F, Haslinger A, Riemenschneider M, Schwarz M, et al. Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimer's disease. Brain Res. 1999;823:104-12 pubmed
Harrison M, Obermueller E, Maisey N, Hoare S, Edmonds K, Li N, et al. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. J Clin Oncol. 2007;25:4542-9 pubmed
Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, et al. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Cytokine. 2008;41:144-9 pubmed publisher
Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, et al. HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells. J Exp Med. 2009;206:169-81 pubmed publisher
Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, et al. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake. Am J Clin Nutr. 2007;86:661-71 pubmed
Bedaiwy M, Falcone T, Goldberg J, Attaran M, Sharma R, Miller K, et al. Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid. J Assist Reprod Genet. 2005;22:161-5 pubmed
Bunck M, Diamant M, Eliasson B, Cornér A, Shaginian R, Heine R, et al. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition. Diabetes Care. 2010;33:1734-7 pubmed publisher
Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, et al. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol. 2008;181:2772-80 pubmed
Nakao T, Kim S, Ohta K, Kawano H, Hino M, Miura K, et al. Role of mitogen-activated protein kinase family in serum-induced leukaemia inhibitory factor and interleukin-6 secretion by bone marrow stromal cells. Br J Pharmacol. 2002;136:975-84 pubmed
Mankowski J, Queen S, Clements J, Zink M. Cerebrospinal fluid markers that predict SIV CNS disease. J Neuroimmunol. 2004;157:66-70 pubmed
Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, et al. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury. Shock. 2004;22:102-7 pubmed
Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, et al. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. Int J Cancer. 2009;125:1092-101 pubmed publisher
Petitto J, Leserman J, Perkins D, Stern R, Silva S, Gettes D, et al. High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status. Behav Med. 2000;25:143-51 pubmed
Wang Z, Xing W, Fan H, Wang K, Zhang H, Wang Q, et al. The novel lipopolysaccharide-binding protein CRISPLD2 is a critical serum protein to regulate endotoxin function. J Immunol. 2009;183:6646-56 pubmed publisher
Tso G, Law H, Tu W, Chan G, Lau Y. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells. Stem Cells. 2010;28:939-54 pubmed publisher
Raffaghello L, Bianchi G, Bertolotto M, Montecucco F, Busca A, Dallegri F, et al. Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche. Stem Cells. 2008;26:151-62 pubmed
product information
Main Category :
ELISAs
SubCategory :
Quantikine Colorimetric Sandwich ELISAs
Molecule :
IL-6
Species :
Human
Catalog Number :
D6050
Long Description :
Human IL-6 Quantikine ELISA Kit
SIZE :
1 Kit
Price (USD) :
495 USD
GBP (Pound Sterling) :
350.00
EURO :
530.00
CHF (Swiss Franc) :
1050.00
SEK (Swedish Krone) :
4900.00
DKK (Danish Krone) :
4080.00
NOK (Norwegian Krone) :
4295.00
ELISA Sensitivity :
0.7 pg/mL
ELISA Range :
3.12-300 pg/mL
ELISA Sample Types :
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Protein Synonyms :
D6050, hIL-6 QKit
Keywords :
IL- 6
more info or order :
company information
R and D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
www.rndsystems.com
800 343-7475
headquarters: USA