product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Anti-Human HLA-DR, FITC, (Clone YE2/36 HLK) (rat IgG2a)
catalog :
MBS520342
quantity :
0.1 mg
price :
230 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
reactivity :
human
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS520342
products type :
Antibody
products full name :
Anti-Human HLA-DR, FITC, (Clone YE2/36 HLK) (rat IgG2a)
products short name :
HLA-DR
products name syn :
HLA-DR, FITC, (Clone YE2/36 HLK) (rat IgG2a); Purified Anti-Human HLA-DR Monoclonal Antibody
other names :
HLA-DR; HLA-DR; HLA class II histocompatibility antigen, DQ beta 1 chain; MHC DQ beta; MHC class2 antigen; lymphocyte antigen; MHC class II antigen DQB1; MHC class II DQ beta chain; MHC class II antigen HLA-DQ-beta-1; MHC class II HLA-DQ beta glycoprotein; major histocompatibility complex, class II, DQ beta 1; N/A
products gene name :
HLA-DR
other gene names :
HLA-DQB1; IDDM1; CELIAC1; HLA-DQB; N/A
uniprot entry name :
Q29900_HUMAN
clonality :
Monoclonal
isotype :
Rat IgG2a
clone :
YE2/36 HLK
host :
Rat
reactivity :
Human
sequence length :
42
specificity :
HLA-DR (HLA-DR Ia alpha chain, cross reactive with mouse H-2, I-A sub-region)
form :
FITC
concentration :
Antibody Concentration: 1.0 ug/106 cells
storage stability :
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugate. For long term storage (Ascites, Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
app notes :
flow cytometry, immunofluorescence1 and immunohistochemistry3 (frozen and paraffin sections).
other info1 :
Immunogen: EHR-B Ramos cells. Donor: immunized AO rat spleen cells. Fusion Partner: Y3 Ag1.2.3 rat myeloma
other info2 :
Presentation: conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
purified anti-human HLA-DR monoclonal antibody recognizes an epitope on the Ia alpha chain of the Human lymphocyte antigen. This antibody has also been shown to recognize the H-2, I-A region of the mouse.
ncbi gi num :
642238
ncbi acc num :
CAA23788.1
uniprot acc num :
Q29900
ncbi mol weight :
5,068 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Asthma Pathway 83120!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!Cell Adhesion Molecules (CAMs) Pathway 83069
ncbi summary :
HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
size :
0.1 mg
price :
230 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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